Pre- and Post-conditioning in Cardiovascular Surgery.

abstract：:The "pleiotropic" effects of statins have been the centre of a considerable research activity. Among the numerous experimental and clinical studies of this field, some focused on the effects of statins on blood pressure (BP), while others reported data on BP together with other parameters. Some of the animal or human ...

journal_title：Current vascular pharmacology

authors： Sarafidis PA,Kanaki AI,Lasaridis AN

更新日期：2007-04-01 00:00:00

abstract：:Chronic kidney disease (CKD), and particularly kidney failure, is associated with accelerated atherosclerosis and approximately a 20-fold increased risk of cardiovascular death. The majority of these patients die from complications directly attributed to atherosclerosis and their life expectancy is decreased. Establis...

journal_title：Current vascular pharmacology

authors： Efstratiadis G,Tziomalos K,Mikhailidis DP,Athyros VG,Hatzitolios A

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:Obstructive Sleep Apnoea (OSA) constitutes the most prevalent form of abnormal respiratory control during sleep in adults. Evidence linked OSA to cardiovascular disease, and the role of OSA in abnormal Blood Pressure (BP) control has been extensively studied. Although longitudinal trials suggest a causativ...

journal_title：Current vascular pharmacology

authors： Wolf J,Narkiewicz K

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Vitamin D is a fat soluble vitamin involved in calcium and bone metabolism; recently its deficiency has been related to cardiovascular disease. In cardiac tissue, vitamin D suppresses metalloproteinases (MMPs) expression, enzymes directly associated with vulnerable plaque. OBJECTIVE:To investigate whether t...

journal_title：Current vascular pharmacology

authors： Machulsky NF,Barchuk M,Gagliardi J,Gonzalez D,Lombardo M,Escudero AG,Gigena G,Blanco F,Schreier L,Fabre B,Berg G

更新日期：2018-01-01 00:00:00

abstract：:Obesity is a risk factor for complications of atherosclerotic vascular disease such as myocardial infarction and stroke. Recent studies have demonstrated that the vascular risk associated with obesity is correlated particularly with visceral adiposity. These clinical observations indicate that various adipose tissue d...

journal_title：Current vascular pharmacology

authors： Ohman MK,Wright AP,Wickenheiser KJ,Luo W,Eitzman DT

更新日期：2009-04-01 00:00:00

abstract：:Autoregulation is a vital homeostatic mechanism that helps maintain constant delivery of oxygen to organs despite fluctuations in arteriolar pressure. Autoregulation of blood flow to elevations in pressure is largely mediated by the myogenic response of small arteries and arterioles which constrict in response to elev...

journal_title：Current vascular pharmacology

authors： Roman RJ,Van Dokkum RP

更新日期：2014-01-01 00:00:00

abstract：:In patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), 25OH-vitamin D (calcidiol) deficiency or insufficiency is a common finding with high prevalence. Numerous epidemiological studies have found an independent association of low levels of calcidiol with increased morbidity and mortality. Wi...

journal_title：Current vascular pharmacology

authors： Brandenburg VM,Kruger T

更新日期：2014-03-01 00:00:00

abstract：:Revascularization procedures used for the treatment of cardiovascular disease can be associated with restenosis, although drug-coated stents have greatly reduced this complication. Both type 2 diabetes (T2DM) and metabolic syndrome (MetS) are associated with a high risk for atherosclerosis and restenosis. Insulin resi...

journal_title：Current vascular pharmacology

authors： Breen DM,Giacca A

更新日期：2011-05-01 00:00:00

abstract：:In this issue of Curr Vasc Pharmacol, Pfeiffer et al. [1] and Glorioso et al. [2] report the efficacy and tolerability of aliskiren/amlodipine single-pill combinations (SPCs) in patients with inadequate blood pressure (BP) response to amlodipine or aliskiren monotherapy, respectively. ...

journal_title：Current vascular pharmacology

authors： Katsiki N,Athyros VG,Mikhailidis DP,Karagiannis A

更新日期：2012-11-01 00:00:00

abstract：:Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of t...

journal_title：Current vascular pharmacology

authors： Haidara MA,Assiri AS,Yassin HZ,Ammar HI,Obradovic MM,Isenovic ER

更新日期：2015-01-01 00:00:00

abstract：:High density lipoprotein (HDL) is recognized as the major negative risk factor of cardiovascular disease and number of anti-atherogenic functions has been ascribed to HDL. HDL is an assembly of a neutral lipid core and an outer shell consisting of polar lipids and proteins. It has been defined many different ways base...

journal_title：Current vascular pharmacology

authors： Vaisar T

更新日期：2012-07-01 00:00:00

abstract：:Although hypertension, hypercholesterolemia and diabetes mellitus (DM) are recognized as major cardio-metabolic risk factors in primary Acute Coronary Syndrome (ACS) prevention, studies focusing on secondary ACS incidence are scarce. In the present study, the association between the aforementioned factors and 10-year ...

journal_title：Current vascular pharmacology

authors： Notara V,Panagiotakos DB,Michalopoulou M,Kouvari M,Tsompanaki E,Verdi M,Vassileiou N,Kalli E,Mantas Y,Kogias Y,Stravopodis P,Papanagnou G,Zombolos S,Pitsavos C,Greecs Study Investigators.

更新日期：2016-01-01 00:00:00

abstract：:Platelet adhesion on vascular wall is the first step following vascular injury. Differential platelet secretion supports angiogenesis and vascular homeostasis. Progenitor cells are pluripotent cells responsible for tissue regeneration and wound healing. Upon ischemia bone marrow-derived progenitor cells are mobilized ...

journal_title：Current vascular pharmacology

authors： Sopova K,Tatsidou P,Stellos K

更新日期：2012-09-01 00:00:00

abstract：:Several lines of evidence suggest a detrimental effect of aldosterone excess on the development of metabolic alterations. Glucose metabolism derangements due to aldosterone action are frequently observed not only in patients with primary aldosteronism but also in patients with obesity. A contribution to the hyperaldos...

journal_title：Current vascular pharmacology

authors： Ronconi V,Turchi F,Appolloni G,di Tizio V,Boscaro M,Giacchetti G

更新日期：2012-03-01 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a syndrome compromising the health of the mother and the fetus. Endothelial damage and reduced metabolism of the vasodilator adenosine occur and fetal hyperinsulinemia associated with deficient insulin response and a metabolic rather than mitogenic phenotype is characteristic of ...

journal_title：Current vascular pharmacology

authors： Guzmán-Gutiérrez E,Abarzúa F,Belmar C,Nien JK,Ramírez MA,Arroyo P,Salomón C,Westermeier F,Puebla C,Leiva A,Casanello P,Sobrevia L

更新日期：2011-11-01 00:00:00

abstract：:This review considers drug combinations and newer treatment strategies for patients with severe hypertriglyceridemia. Hypertriglyceridemia is associated with an atherogenic metabolic profile and in most studies with increased cardiovascular disease risk. Patients with severe hypertriglyceridemia also have increased in...

journal_title：Current vascular pharmacology

authors： Filippatos TD,Elisaf MS

更新日期：2014-01-01 00:00:00

abstract：:Cardiovascular failure in sepsis involves a combination of hypovolemia, decreased vascular tone, myocardial depression and microcirculatory alterations. Fluids represent the first line therapeutic intervention, with controversy regarding the type of fluid. Recent data indicate that albumin is safe and might even be be...

journal_title：Current vascular pharmacology

authors： De Backer D,Scolletta S

更新日期：2013-03-01 00:00:00

abstract：:Hypercoagulability is widely associated with sepsis, inflammation, diabetes, cancers, aging, and many pathological conditions, resulting in life-threatening disseminated intravascular coagulation (DIC), venous thrombosis, thromboembolism, cardiovascular complications, or even deadly multiple organ failure. Relieving c...

journal_title：Current vascular pharmacology

authors： Chu AJ

更新日期：2004-07-01 00:00:00

abstract：:The aim of this review is to present, critically appraise and qualitatively synthesize current evidence on the risk of type 2 diabetes mellitus (T2DM) development during menopause, the management of climacteric symptoms in women with T2DM and the management of T2DM in postmenopausal women. Menopause represents the end...

journal_title：Current vascular pharmacology

authors： Paschou SA,Anagnostis P,Pavlou DI,Vryonidou A,Goulis DG,Lambrinoudaki I

更新日期：2019-01-01 00:00:00

abstract：:Central arterial systolic blood pressure is a very important factor in the pathophysiology of cardiovascular diseases. Central arterial pressure is a better predictor of cardiovascular risk than peripheral brachial blood pressure. Measurement of central blood pressure is useful for a diagnosis of spurious systolic hyp...

journal_title：Current vascular pharmacology

authors： Stepień M,Banach M,Jankowski P,Rysz J

更新日期：2010-11-01 00:00:00

abstract：: ...

journal_title：Current vascular pharmacology

authors： Cortese F

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:In various cardiac diseases, thrombembolism constitutes a major risk, and in these patients clinically silent microembolic signals (MES) are detectable within the transcranial Doppler frequency spectrum (TCD) of the major brain arteries. MES are already an accepted surrogate parameter of the future risk of s...

journal_title：Current vascular pharmacology

authors： Dittrich R,Ringelstein EB

更新日期：2008-10-01 00:00:00

abstract：:In the last decade there have been considerable advances in the understanding of the pathophysiology of malignant ventricular tachyarrhythmias (VA) and Sudden Cardiac Death (SCD). Over 80% of SCD occurs in patients with organic heart disease. However, approximately 10-15% of SCD occurs in the presence of structurally ...

journal_title：Current vascular pharmacology

authors： El-Sherif N,Pedalino R,Himel H 4th

更新日期：2009-07-01 00:00:00

abstract：:Biomarkers are used in medicine to facilitate diagnosis, assess risk, direct therapy and determine efficacy of treatment. Sensitivity and specificity are essential in order for a biomarker to be useful. Brain natriuretic peptide (BNP) and C-reactive protein (CRP) are considered biomarkers of cardiovascular disease. Ho...

journal_title：Current vascular pharmacology

authors： Miller VM,Redfield MM,McConnell JP

更新日期：2007-01-01 00:00:00

abstract：:Aspirin plays a pivotal role in the management of patients with Coronary Artery Disease (CAD) with well-recognised benefits of reducing recurrent myocardial infarction and minimising the risk of stent thrombosis for those undergoing Percutaneous Coronary Intervention (PCI). Dual antiplatelet therapy is mandated for pa...

journal_title：Current vascular pharmacology

authors： Kassimis G,Raina T,Alexopoulos D

更新日期：2019-01-01 00:00:00

abstract：:Angiogenesis is central to cardiac repair following myocardial infarction (MI). Cardiac angiotensin converting enzyme (ACE)2 significantly increased postMI, which is coincident with activated angiogenesis. The function of ACE2 is to generate angiotensin (Ang)1-7, an active peptide with cellular actions mediated by Mas...

journal_title：Current vascular pharmacology

authors： Zhao W,Zhao T,Chen Y,Sun Y

更新日期：2015-01-01 00:00:00

abstract：:Obesity and Gestational Diabetes Mellitus (GDM) are the most frequent pathologies affecting mothers and offspring during pregnancy. Both conditions have shown a sustained increase in their prevalence in recent years, and they worsen the outcome of pregnancy and the long-term health of mothers. Obesity increases the ri...

journal_title：Current vascular pharmacology

authors： Poblete JA,Olmos P

更新日期：2021-01-01 00:00:00

abstract：:Postprandial hypertriglyceridaemia, defined as an increase in plasma triglyceride-containing lipoproteins following a fat meal, is a potential risk predictor of atherosclerotic cardiovascular disease and other chronic diseases. Several non-modifiable factors (genetics, age, sex and menopausal status) and lifestyle fac...

journal_title：Current vascular pharmacology

authors： Kolovou GD,Watts GF,Mikhailidis DP,Pérez-Martínez P,Mora S,Bilianou H,Panotopoulos G,Katsiki N,Ooi TC,Lopez-Miranda J,Tybjærg-Hansen A,Tentolouris N,Nordestgaard BG

更新日期：2019-01-01 00:00:00

abstract：:Both endothelin(ET)-1 and oxidative stress have been the subjects of intense investigation within the cardiovascular field over the past decade and a half, yet little is known about the precise relationship between these important modulators of vascular function. There is a firm evidence that ET-1 can stimulate the pr...

journal_title：Current vascular pharmacology

authors： Pollock DM,Pollock JS

更新日期：2005-10-01 00:00:00

abstract：:The vascular endothelium is a monolayer of cells between the vessel lumen and the vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized from the amino acid L-arginine in endothelial cells by the constitutive calcium-calmodulin-dependent enzyme nitric oxide synthase (NOS). This subst...

journal_title：Current vascular pharmacology

authors： Tousoulis D,Kampoli AM,Tentolouris C,Papageorgiou N,Stefanadis C

更新日期：2012-01-01 00:00:00