当前位置： SCI文献检索 > BIOMATERIALS期刊下所有文献 > Remote and reversible control of in vivo bacteria clustering by NIR-driven multivalent upconverting nanosystems.

Remote and reversible control of in vivo bacteria clustering by NIR-driven multivalent upconverting nanosystems.

Abstract：

:Achieving remote and reversible control of bacterial cell-cell interactions associated with interference with pathological processes in living systems remains a challenge owing to the complexity of the in vivo microenvironment and the lack of regulation systems. We present, for the first time, the development of a versatile platform to achieve NIR-driven reversible bacterial clustering both in vitro and in vivo. This platform consisted of β-CD modified UCNP (UCNP-CD) and photochromic azobenzene glycoconjugates (azo-man), which could dynamically display d-mannose bioactive ligands. Specifically, by virtue of the noncovalent yet strong multivalent interactions between bacteria and nanosystems, robust bacterial clusters could be formed even in vivo within 1 h. Upon NIR stimulation, the upconverted emissions from UCNPs triggered the continuous isomerization of azo-man, leading to dissociation of the nanosystems and dispersion of bacterial clusters. Moreover, in vivo pathogenic infection process could be interfered with the NIR-switched bacterial agglutination. Most importantly, the noninvasive and deep-tissue-penetrating nature of NIR made it possible for dynamically regulation of cellular interactions with minimized influence to both normal cells and nature bacteria flora. This strategy would bring new perspectives for anti-virulence therapeutics and in-depth investigations of specific physiological phenomena.

journal_name

Biomaterials

journal_title

Biomaterials

authors

Li W,Dong K,Wang H,Zhang P,Sang Y,Ren J,Qu X

doi

10.1016/j.biomaterials.2019.119310

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

119310

eissn

0142-9612

issn

1878-5905

pii

S0142-9612(19)30409-0

journal_volume

217

pub_type

杂志文章

相关文献

BIOMATERIALS文献大全
  • Cross-linking of dermal sheep collagen using a water-soluble carbodiimide.

    abstract：:A cross-linking method for collagen-based biomaterials was developed using the water-soluble carbodiimide 1-ethyl-3-(3-dimethyl aminopropyl)carbodiimide hydrochloride (EDC). Cross-linking using EDC involves the activation of carboxylic acid groups to give O-acylisourea groups, which form cross-links after reaction wit...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/0142-9612(96)81413-x

    authors： Olde Damink LH,Dijkstra PJ,van Luyn MJ,van Wachem PB,Nieuwenhuis P,Feijen J

    更新日期：1996-04-01 00:00:00

  • Novel multimeric IL-1 receptor antagonist for the treatment of rheumatoid arthritis.

    abstract：:Protein therapeutics targeting inflammatory mediators have shown great promise for the treatment of autoimmunities such as rheumatoid arthritis (RA). However, a significant challenge in this area has been their low in vivo stability and consequently their severely compromised therapeutic efficacy. One such therapeutic...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2014.11.041

    authors： Pasi S,Kant R,Gupta S,Surolia A

    更新日期：2015-02-01 00:00:00

  • The promotion of chondrogenesis in adipose-derived adult stem cells by an RGD-chimeric protein in 3D alginate culture.

    abstract：:The dynamic regulation of integrin-binding peptides is crucial for chondrogenic differentiation. Here, we revealed the feasibility for flexible modification of RGD by embedding a large molecular weight and slightly charged (isoelectric point, 6-6.25) RGD-chimeric protein (CBD-RGD) with cellulose-binding domain (CBD) i...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2009.07.064

    authors： Chang JC,Hsu SH,Chen DC

    更新日期：2009-10-01 00:00:00

  • Synthetic high-density lipoprotein-like nanoparticles potently inhibit cell signaling and production of inflammatory mediators induced by lipopolysaccharide binding Toll-like receptor 4.

    abstract：:Toll-like receptor 4 (TLR4) plays a critical role in the innate immune system. Stimulation of TLR4 occurs upon binding lipopolysaccharide (LPS), a component of Gram-negative bacterial cell walls. Due to the potency of the induced inflammatory response, there is a growing interest in agents that can most proximally mod...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2016.05.021

    authors： Foit L,Thaxton CS

    更新日期：2016-09-01 00:00:00

  • Tumor-activatable ultrasmall nanozyme generator for enhanced penetration and deep catalytic therapy.

    abstract：:Tumor-activatable ultrasmall nanozyme generation is an unprecedented strategy to overcome intrinsically fatal defects of traditional reactive oxygen species (ROS)-based nanoagents for deep tumor penetration, including limited tissue-penetrating depth of external energy, heavy reliance on oxygen and nonspecific toxicit...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2020.120263

    authors： Liu X,Liu Z,Dong K,Wu S,Sang Y,Cui T,Zhou Y,Ren J,Qu X

    更新日期：2020-11-01 00:00:00

  • Long-term histological evaluation of hydroxyapatite ceramics in humans.

    abstract：:We have investigated the interface between bone and hydroxyapatite (HA) chronically implanted in man. By light microscopy, HA appeared to bind directly to bone without intervening fibrous tissue. By transmission electron microscopy, two patterns were noted: (1) HA either bound directly to bone; or (2) electron-dense m...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/0142-9612(95)91093-e

    authors： Oguchi H,Ishikawa K,Mizoue K,Seto K,Eguchi G

    更新日期：1995-01-01 00:00:00

  • Immobilization of proteins on poly(methyl methacrylate) films.

    abstract：:Polymethyl methacrylate (PMMA) films were treated by oxygen plasma discharge followed by acrylic acid (AA) grafting. The amount of carboxyl groups introduced by the grafting of AA on to the film surfaces was in the range 0.47-9.48 mumol/cm2, depending on the pressure of the plasma chamber during the discharge treatmen...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/0142-9612(93)90045-4

    authors： Kang IK,Kwon BK,Lee JH,Lee HB

    更新日期：1993-08-01 00:00:00

  • FT-IR study for hydroxyapatite/collagen nanocomposite cross-linked by glutaraldehyde.

    abstract：:FT-IR analysis was performed for the hydroxyapatite (HAp)/collagen (COL) nanocomposite cross-linked by glutaraldehyde (GA). The amide bands I, II and III from COL matrix, and phosphate and carbonate bands from HAp were identified. The amide B band arising from C-H stretching mode showed a sensitive conformation by the...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/s0142-9612(02)00232-6

    authors： Chang MC,Tanaka J

    更新日期：2002-12-01 00:00:00

  • Signalling pathways involved in the activation of dendritic cells by layered double hydroxide nanoparticles.

    abstract：:Layered double hydroxide (LDH) nanoparticles are attractive as potential drug vectors for the targeting not only of tissues, but also of intracellular organelles, and particularly the acidic endolysosomes created after cell endocytosis. The purpose of this study was to investigate the ability of LDH nanoparticles desi...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2009.09.095

    authors： Li A,Qin L,Zhu D,Zhu R,Sun J,Wang S

    更新日期：2010-02-01 00:00:00

  • A preliminary study on osteoinduction of two kinds of calcium phosphate ceramics.

    abstract：:With respect to the effect of material factors on calcium phosphate biomaterial-induced osteogenesis, the osteoinductive property of two kinds of porous hydroxyapatite ceramics, which were made by different producers, was investigated in dorsal muscles of dogs. One hydroxyapatite ceramic (S-HA), macroporous implants w...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/s0142-9612(99)00075-7

    authors： Yuan H,Kurashina K,de Bruijn JD,Li Y,de Groot K,Zhang X

    更新日期：1999-10-01 00:00:00

  • Temperature sensitive contact lenses for triggered ophthalmic drug delivery.

    abstract：:Ophthalmic drug delivery through eye drops is inefficient because of low corneal bioavailability and short residence time in tears. Contact lenses are ideally suited for extended and targeted drug delivery to cornea, but commercial contact lenses release ophthalmic drugs for only 1-2 h. This study focuses on dispersin...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2011.10.076

    authors： Jung HJ,Chauhan A

    更新日期：2012-03-01 00:00:00

  • Crystallization at the polymer/calcium-phosphate interface in a sterilized injectable bone substitute IBS.

    abstract：:Calcium phosphate (CaP) ceramics are the main raw materials used to elaborate blocks or granules for bone substitutes. In this study, injectable bone substitutes (IBS) were developed for applications in orthopedic or dental surgery. Sterile, ready-to-use composite containing CaP granules (biphasic calcium phosphate, B...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/s0142-9612(02)00015-7

    authors： Schmitt M,Weiss P,Bourges X,Amador del Valle G,Daculsi G

    更新日期：2002-07-01 00:00:00

  • Cancer therapy and fluorescence imaging using the active release of doxorubicin from MSPs/Ni-LDH folate targeting nanoparticles.

    abstract：:Hierarchical structured nanomaterials with diverse functionality, such as magnetic susceptibility, stimuli-responsiveness, environmental sensing and biocompatibility, are highly sought after for biomedicine and biodetection alike. In this study, we designed and fabricated a new kind of multifunctional core/shell nanos...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2013.06.046

    authors： Li D,Zhang YT,Yu M,Guo J,Chaudhary D,Wang CC

    更新日期：2013-10-01 00:00:00

  • Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy.

    abstract：:Cationic polymers are currently being studied as non-viral vectors to deliver therapeutic DNA into cells. In this study, a series of trehalose-based glycopolymers containing four secondary amines in the repeat unit were synthesized via the 'click reaction' [degrees of polymerization (n(w))=35, 53, 75, or 100] to eluci...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2007.01.037

    authors： Srinivasachari S,Liu Y,Prevette LE,Reineke TM

    更新日期：2007-06-01 00:00:00

  • The biocompatibility of dibutyryl chitin in the context of wound dressings.

    abstract：:Dibutyryl chitin (DBC) is a modified chitin carrying butyryl groups at 3 and 6 positions; its peculiarity is that it dissolves promptly in common solvents, while being insoluble in aqueous systems. The high biocompatibility of dibutyryl chitin in the form of films and non-wovens has been demonstrated for human, chick ...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2005.03.006

    authors： Muzzarelli RA,Guerrieri M,Goteri G,Muzzarelli C,Armeni T,Ghiselli R,Cornelissen M

    更新日期：2005-10-01 00:00:00

  • A microarray approach to the identification of polyurethanes for the isolation of human skeletal progenitor cells and augmentation of skeletal cell growth.

    abstract：:The present study has examined the efficacy of a polymer microarray platform to screen a library of polyurethanes for applications such as human skeletal progenitor cell isolation and surface modification of tissue engineering scaffolds to enhance skeletal cell growth and differentiation. Analysis of polyurethane micr...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2008.10.038

    authors： Tare RS,Khan F,Tourniaire G,Morgan SM,Bradley M,Oreffo RO

    更新日期：2009-02-01 00:00:00

  • A "room-temperature" injection molding/particulate leaching approach for fabrication of biodegradable three-dimensional porous scaffolds.

    abstract：:A "room-temperature" injection molding approach combined with particulate leaching (RTIM/PL) has been, for the first time, developed in this work to fabricate three-dimensional porous scaffolds composed of biodegradable polyesters for tissue engineering. In this approach, a "wet" composite of particulate/polymer/solve...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2005.05.105

    authors： Wu L,Jing D,Ding J

    更新日期：2006-01-01 00:00:00

  • Multifunctional mesoporous nanoparticles as pH-responsive Fe(2+) reservoirs and artemisinin vehicles for synergistic inhibition of tumor growth.

    abstract：:Artemisinin (ART) is an iron-dependent anti-cancer drug. However, simultaneous delivery of hydrophobic ART and Fe(2+) ions into cancer cells remains a major challenge. Herein, we reported Fe3O4@C/Ag@mSiO2 (FCA@mSiO2) multifunctional nanocarriers which can load ART as high as 484 mg/g. Moreover, FCA@mSiO2 nanoparticles...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2014.04.028

    authors： Chen J,Guo Z,Wang HB,Zhou JJ,Zhang WJ,Chen QW

    更新日期：2014-08-01 00:00:00

  • High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation.

    abstract：:Elasticity of cellular microenvironments strongly influences cell motility, phagocytosis, growth and differentiation. Currently, the relationship between the cell behaviour and matrix stiffness is being studied for cells seeded on planar substrates, however in three-dimensional (3D) microenvironments cells may experie...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2010.10.033

    authors： Kumachev A,Greener J,Tumarkin E,Eiser E,Zandstra PW,Kumacheva E

    更新日期：2011-02-01 00:00:00

  • Immunomodulatory properties of chitosan polymers.

    abstract：:The introduction of vaccines is regarded as one of the most successful medical interventions to date. However, there is a clear need for the development of new vaccines for diseases which require the induction of a potent cellular immune response. Advancements in the field of vaccine research have resulted in a move a...

    journal_title：Biomaterials

    pub_type： 杂志文章,评审

    doi：10.1016/j.biomaterials.2018.08.054

    authors： Moran HBT,Turley JL,Andersson M,Lavelle EC

    更新日期：2018-11-01 00:00:00

  • Hydroxyapatite formation on alkali-treated titanium with different content of Na+ in the surface layer.

    abstract：:Titanium can form a bone-like apatite layer on its surface in SBF when it is treated in NaOH. When pre-treated titanium is exposed to SBF, the alkali ions are released from the surface into the surrounding fluid. The Na+ ions increase the degree of supersaturation of the soaking solution with respect to apatite by inc...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/s0142-9612(02)00043-1

    authors： Jonásová L,Müller FA,Helebrant A,Strnad J,Greil P

    更新日期：2002-08-01 00:00:00

  • pH-sensitive degradable chimaeric polymersomes for the intracellular release of doxorubicin hydrochloride.

    abstract：:pH-sensitive degradable chimaeric polymersomes were developed based on asymmetric poly(ethylene glycol)-b-poly(2,4,6-trimethoxybenzylidene-1,1,1-tris(hydroxymethyl)ethane methacrylate)-b-poly(acrylic acid) (PEG-PTTMA-PAA) triblock copolymers for active loading as well as triggered intracellular release of hydrophilic ...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2012.06.034

    authors： Du Y,Chen W,Zheng M,Meng F,Zhong Z

    更新日期：2012-10-01 00:00:00

  • In vivo β-catenin attenuation by the integrin α5-targeting nano-delivery strategy suppresses triple negative breast cancer stemness and metastasis.

    abstract：:Cancer stem cells (CSCs) play pivotal roles in cancer metastasis, and strategies targeting cancer stemness may greatly reduce cancer metastasis and improve patients' survival. The canonical Wnt/β-catenin pathway plays critical roles in CSC generation and maintenance as well as in normal stem cells. Non-specifically su...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2018.10.019

    authors： Li Y,Xiao Y,Lin HP,Reichel D,Bae Y,Lee EY,Jiang Y,Huang X,Yang C,Wang Z

    更新日期：2019-01-01 00:00:00

  • Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics.

    abstract：:Natural particles ranging from various cell membranes to nascent proteins are highly optimized for their specific functions in vivo and possess features that are desired in drug delivery carriers. However, the current endeavor in research on bioparticles is still seeking the appropriate strategy to shield multiple age...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2019.119413

    authors： Wang R,Zhang C,Li J,Huang J,Opoku-Damoah Y,Sun B,Zhou J,Di L,Ding Y

    更新日期：2019-11-01 00:00:00

  • Preparation of poly(ethylene glycol)-polystyrene block copolymers using photochemistry of dithiocarbamate as a reduced cell-adhesive coating material.

    abstract：:This article reports a novel preparation method of poly(ethylene glycol) (PEG)-polystyrene (PST) amphiphilic block copolymers with well-defined block lengths by using photopolymerization of an iniferter, benzyl N,N-diethyldithiocarbamate. PEG macroiniferters, which were prepared by end-capping of PEG monomethyl ethers...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/s0142-9612(98)00252-x

    authors： Nakayama Y,Miyamura M,Hirano Y,Goto K,Matsuda T

    更新日期：1999-05-01 00:00:00

  • Evaluation of the effect of three surface treatments on the biocompatibility of 316L stainless steel using human differentiated cells.

    abstract：:AISI 316L stainless steel (SS) is widely used in orthopaedic implantology, although biological complications may result from its insufficient mechanical and tribological properties. In order to improve the wear and corrosion resistance as well as the hardness of 316L SS, three surface treatments, derived from those ap...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/0142-9612(96)82723-2

    authors： Bordji K,Jouzeau JY,Mainard D,Payan E,Delagoutte JP,Netter P

    更新日期：1996-03-01 00:00:00

  • The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro.

    abstract：:The effects of chitin [(1 --> 4)-2-acetamido-2-deoxy-beta-D-glucan] and its partially deacetylated derivatives, chitosans, on the proliferation of human dermal fibroblasts and keratinocytes were examined in vitro. Chitosans with relatively high degrees of deacetylation strongly stimulated fibroblast proliferation whil...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/s0142-9612(01)00042-4

    authors： Howling GI,Dettmar PW,Goddard PA,Hampson FC,Dornish M,Wood EJ

    更新日期：2001-11-01 00:00:00

  • Engineered skeletal muscle tissue networks with controllable architecture.

    abstract：:The engineering of functional skeletal muscle tissue substitutes holds promise for the treatment of various muscular diseases and injuries. However, no tissue fabrication technology currently exists for the generation of a relatively large and thick bioartificial muscle made of densely packed, uniformly aligned, and d...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2008.11.015

    authors： Bian W,Bursac N

    更新日期：2009-03-01 00:00:00

  • In situ polymerization of tropoelastin in the absence of chemical cross-linking.

    abstract：:Tropoelastin, the polypeptide monomer precursor of elastin, is covalently cross-linked to give stable elastic structures. We show here that elastic biomaterials can be generated from tropoelastin in the absence of the classically accepted cross-linking pathway. Under alkaline conditions tropoelastin proceeds through a...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2008.10.018

    authors： Mithieux SM,Tu Y,Korkmaz E,Braet F,Weiss AS

    更新日期：2009-02-01 00:00:00

  • Tumor microenvironment sensitive doxorubicin delivery and release to glioma using angiopep-2 decorated gold nanoparticles.

    abstract：:Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was loaded with doxorubicin (DOX) through hydrazone, an acid-responsive linker, and was functionalized with angiopep-2, a specific ligand of lo...

    journal_title：Biomaterials

    pub_type： 杂志文章

    doi：10.1016/j.biomaterials.2014.10.007

    authors： Ruan S,Yuan M,Zhang L,Hu G,Chen J,Cun X,Zhang Q,Yang Y,He Q,Gao H

    更新日期：2015-01-01 00:00:00