Abstract：
:FT-IR analysis was performed for the hydroxyapatite (HAp)/collagen (COL) nanocomposite cross-linked by glutaraldehyde (GA). The amide bands I, II and III from COL matrix, and phosphate and carbonate bands from HAp were identified. The amide B band arising from C-H stretching mode showed a sensitive conformation by the degree of cross-linking. The amide I band showed a complicate conformational change by the degree of cross-linking. The characteristic amide I band at 1685 cm(-1), which is known as an aging parameter in the biological bone, did not show a monotonous tendency by the degree of cross-linking. The relative contents of the organics in the cross-linked HAp/COL nanocomposite were evaluated as an integration ratio between the amide I band at 1600-1700 cm(-1) and PO(4)(3-) band at 900-1200 cm(-1). The increase of the organics content by the cross-linking is enabled by the further organization of Ca(2+) ions of HAp crystals in HAp/COL nanocomposite. The complicate conformational behavior in the amide I, II and III bands seems to be affected by the cross-linking induced directional arrangement of HAp/COL nanocomposite fibrils.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Chang MC,Tanaka Jdoi
10.1016/s0142-9612(02)00232-6keywords:
subject
Has Abstractpub_date
2002-12-01 00:00:00pages
4811-8issue
24eissn
0142-9612issn
1878-5905pii
S0142961202002326journal_volume
23pub_type
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