Evaluation of the effect of three surface treatments on the biocompatibility of 316L stainless steel using human differentiated cells.

abstract：:A series of coumarin fluorophores (1-3), each bearing a double bond conjugated quinoline unit that can undergo a Michael-type reaction with thiol-containing compounds, is reported. These systems, designed to provide so-called turn-on changes in fluorescence response when exposed to thiols, act as fluorescent chemical ...

journal_title：Biomaterials

authors： Jung HS,Han JH,Pradhan T,Kim S,Lee SW,Sessler JL,Kim TW,Kang C,Kim JS

更新日期：2012-01-01 00:00:00

abstract：:Bioactive glasses are potentially useful as bone defect fillers, and vascular endothelial growth factor (VEGF) has demonstrated benefit in bone regeneration as well. We hypothesized that the specific combination of prolonged localized VEGF presentation from a matrix coated with a bioactive glass may enhance bone regen...

journal_title：Biomaterials

authors： Leach JK,Kaigler D,Wang Z,Krebsbach PH,Mooney DJ

更新日期：2006-06-01 00:00:00

abstract：:The design of peptide-based subunit vaccine formulations for the direct delivery of tumor antigen peptides (Aps) to dendritic cells (DCs) localized within draining lymph nodes (DLNs) is challenging. Mature DCs (mDCs) are abundantly distributed within DLNs but have dramatically reduced endocytic uptake and antigen-proc...

journal_title：Biomaterials

authors： Qian Y,Jin H,Qiao S,Dai Y,Huang C,Lu L,Luo Q,Zhang Z

更新日期：2016-08-01 00:00:00

abstract：:The study was to produce a novel hybrid poly-(lactic-co-glycolic acid) (PLGA)-gelatin/chondroitin/hyaluronate (PLGA-GCH) scaffold and evaluate its potentials in cartilage repair. The porous PLGA-GCH scaffold was developed to mimic the natural extra cellular matrix of cartilage. The differentiated mesenchymal stem cell...

journal_title：Biomaterials

authors： Fan H,Hu Y,Zhang C,Li X,Lv R,Qin L,Zhu R

更新日期：2006-09-01 00:00:00

abstract：:Specifically inhibiting the proliferation of activated macrophages and clearing the high levels of reactive oxygen species (ROS) secreted by macrophages is crucial for osteoarthritis (OA) treatment. Moreover, if the clearance of these high levels of ROS can be simultaneously used to induce oxidation-responsive release...

journal_title：Biomaterials

authors： Yang G,Fan M,Zhu J,Ling C,Wu L,Zhang X,Zhang M,Li J,Yao Q,Gu Z,Cai X

更新日期：2020-10-01 00:00:00

abstract：:Sol-gel derived porous silica carriers for the controlled release of proteins were synthesized using a room temperature process. The materials are intended to serve as both substrates for bone growth as well as to allow incorporated proteins such as growth factors to diffuse out and stimulate cell function and tissue ...

journal_title：Biomaterials

authors： Santos EM,Radin S,Ducheyne P

更新日期：1999-09-01 00:00:00

abstract：:This study was designed to develop a skin permeable recombinant low-molecular-weight protamine (LMWP) conjugated epidermal growth factor (EGF) (rLMWP-EGF) by linking a highly positive charged LMWP to the N-terminal of EGF through genetic recombination. We evaluated its biological activity, skin permeability, and wound...

journal_title：Biomaterials

authors： Choi JK,Jang JH,Jang WH,Kim J,Bae IH,Bae J,Park YH,Kim BJ,Lim KM,Park JW

更新日期：2012-11-01 00:00:00

abstract：:Scaffold design plays a crucial role in developing graft-based regenerative strategies, especially when intended to be used in a highly ordered nerve tissue. Here we describe a hybrid matrix approach, which combines the structural properties of collagen (type I) with the epitope-presenting ability of peptide amphiphil...

journal_title：Biomaterials

authors： Sur S,Pashuck ET,Guler MO,Ito M,Stupp SI,Launey T

更新日期：2012-01-01 00:00:00

abstract：:The limited intrinsic repair capacity of articular cartilage has stimulated continuing efforts to develop tissue engineered analogues. Matrices composed of type II collagen and chondroitin sulfate (CS), the major constituents of hyaline cartilage, may create an appropriate environment for the generation of cartilage-l...

journal_title：Biomaterials

authors： Pieper JS,van der Kraan PM,Hafmans T,Kamp J,Buma P,van Susante JL,van den Berg WB,Veerkamp JH,van Kuppevelt TH

更新日期：2002-08-01 00:00:00

abstract：:Renal regeneration approaches offer great potential for the treatment of chronic kidney disease, but their availability remains limited by the clinical challenges they pose. In the present study, we used continuous detergent perfusion to generate decellularized (DC) rat kidney scaffolds. The scaffolds retained intact ...

journal_title：Biomaterials

authors： Yu YL,Shao YK,Ding YQ,Lin KZ,Chen B,Zhang HZ,Zhao LN,Wang ZB,Zhang JS,Tang ML,Mei J

更新日期：2014-08-01 00:00:00

abstract：:Most urgent health problems are related to a blood vessel formation failure. The use of stem cells from different sources or species for both in vitro and in vivo engineering of endothelium does not necessarily imply their direct commitment towards a vascular phenotype. In the present study, we used human amniotic flu...

journal_title：Biomaterials

authors： Mirabella T,Cilli M,Carlone S,Cancedda R,Gentili C

更新日期：2011-05-01 00:00:00

abstract：:The removal of tenacious dental plaque is of paramount importance; however, early diagnosis can be a challenging task in dental clinics due to the limitations of current approaches, specifically X-ray-based techniques. We have approached this problem by integrating antibacterial properties and X-ray contrast enhanceme...

journal_title：Biomaterials

authors： Ostadhossein F,Misra SK,Tripathi I,Kravchuk V,Vulugundam G,LoBato D,Selmic LE,Pan D

更新日期：2018-10-01 00:00:00

abstract：:Reconstruction of the genitourinary tract, using engineered urological tissues, requires a mechanically stable biodegradable and biocompatible scaffold and cultured cells. Such engineered autologous tissue would have many clinical implications. In this study a highly porous biodegradable polyesterurethane-foam, DegraP...

journal_title：Biomaterials

authors： Danielsson C,Ruault S,Simonet M,Neuenschwander P,Frey P

更新日期：2006-03-01 00:00:00

abstract：:This study examined the nature of the surface presented by a machinable feldspathic porcelain and by a machinable glass-ceramic for bonding to conventional composite luting agents and measured the bond strengths which may be achieved with various surface treatments. There was no significant difference between the bond...

journal_title：Biomaterials

authors： Jedynakiewicz NM,Martin N

更新日期：2001-04-01 00:00:00

abstract：:We report here the development of a chitosan/beta-glycerophosphate(Ch/beta-GP) thermo-sensitive gel to deliver ellagic acid (EA) for cancer treatment. The properties of the Ch/beta-GP gels were characterized regarding chemical structure, surface morphology, and viscoelasticity. In vitro EA release rate from the EA loa...

journal_title：Biomaterials

authors： Kim S,Nishimoto SK,Bumgardner JD,Haggard WO,Gaber MW,Yang Y

更新日期：2010-05-01 00:00:00

abstract：:The aim of this in vitro study was to evaluate the antimicrobial activity, the substantivity, and surface effects of the inclusion compound tetracycline: beta-cyclodextrin on bovine roots. The antimicrobial activity was assessed by dentine slabs which had been immersed in the inclusion complex in concentrations 8.0%, ...

journal_title：Biomaterials

authors： Pataro AL,Franco CF,Santos VR,Cortés ME,Sinisterra RD

更新日期：2003-03-01 00:00:00

abstract：:The carboxymethylcellulose-gelatine carrier system was investigated for invertase immobilization. Chromium (III) acetate, chromium (III) sulphate and potassium chromium (III) sulphate were used as cross-linking agents. Effect of carboxymethylcellulose-gelatine ratio and cross-linker concentration on immobilized enzyme...

journal_title：Biomaterials

authors： Emregül E,Sungur S,Akbulut U

更新日期：1996-07-01 00:00:00

abstract：:Using the material technique recently developed by us, we prepared a micropattern on poly(ethylene glycol) (PEG) hydrogel to keep background resistant to cell adhesion for a long time, which made examination of differentiation of localized stem cells available. Our micropattern designed in this paper prevented or ensu...

journal_title：Biomaterials

authors： Tang J,Peng R,Ding J

更新日期：2010-03-01 00:00:00

abstract：:Material features proved to exert a potent influence on cell behaviour in terms of adhesion, migration and differentiation. In particular, biophysical and biochemical signals on material surfaces are able to affect focal adhesion distribution and cytoskeletal assemblies, which are known to regulate signalling pathways...

journal_title：Biomaterials

authors： Natale CF,Ventre M,Netti PA

更新日期：2014-03-01 00:00:00

abstract：:Expansion of hematopoietic stem cells (HSCs) from cord blood is highly desired for treatment and transplantation of adult patients for hematologic diseases. For efficient proliferation of HSCs, CD34(+) cells from cord blood were co-cultured with microencapsulated murine stromal cells (HESS-5) or immortalized human mes...

journal_title：Biomaterials

authors： Fujimoto N,Fujita S,Tsuji T,Toguchida J,Ida K,Suginami H,Iwata H

更新日期：2007-11-01 00:00:00

abstract：:A surface functionalization strategy that produces substrates with well-controlled ligand density is critical to investigating the role of cell-substrate interactions in regulating cell adhesion, viability, migration, proliferation and differentiation. Towards this end, we have designed and synthesized a triblock prot...

journal_title：Biomaterials

authors： Fischer SE,Liu X,Mao HQ,Harden JL

更新日期：2007-08-01 00:00:00

abstract：:Islet transplantation is a method for the treatment of type 1 diabetes mellitus (DM) and has been widely performed around the world. The long-term cryopreservation of islets shows many advantages in the field of islet transplantation. Previous studies have described the development of sheet-type polyvinyl alcohol (PVA...

journal_title：Biomaterials

authors： Qi Z,Shen Y,Yanai G,Yang K,Shirouzu Y,Hiura A,Sumi S

更新日期：2010-05-01 00:00:00

abstract：:The aim of this study was to develop an effective drug delivery system for the simultaneous topical delivery of two anti-inflammatory drugs, spantide II (SP) and ketoprofen (KP). To achieve this primary goal, we have developed a skin permeating nanogel system (SPN) containing surface modified polymeric bilayered nanop...

journal_title：Biomaterials

authors： Shah PP,Desai PR,Patel AR,Singh MS

更新日期：2012-02-01 00:00:00

abstract：:A major goal of bone tissue engineering is to design better scaffold configuration and materials to better control osteoblast behavior. Nanoporous architecture has been shown to significantly affect cellular response. In this work, nanoporous alumina membranes were fabricated by a two-step anodization method to invest...

journal_title：Biomaterials

authors： Popat KC,Leary Swan EE,Mukhatyar V,Chatvanichkul KI,Mor GK,Grimes CA,Desai TA

更新日期：2005-08-01 00:00:00

abstract：:Poly(vinyl alcohol)-heparin hydrogels with varying water content were synthesized for use as sensor catheter membranes. Films were cast from aqueous mixtures of poly(vinyl alcohol) (PVA), a photosensitive cross-linker p-diazonium diphenyl amine polymer (PA), glutaraldehyde (GA) and heparin. After drying, the films wer...

journal_title：Biomaterials

authors： Brinkman E,van der Does L,Bantjes A

更新日期：1991-01-01 00:00:00

abstract：:PVA-AA, an esterification product of poly(vinyl alcohol) and acryloyl chloride, was synthesized and tested for its dentine bonding ability as an additive to 2-hydroxyethyl methacrylate (HEMA). The dentine bonding strength increased significantly by increasing the concentration of PVA-AA in HEMA. The dentine tensile bo...

journal_title：Biomaterials

authors： Gung YW,Kuo SM,Wang YJ

更新日期：1997-02-01 00:00:00

abstract：:In spite of good prospects for bone morphogenetic proteins (BMP) applications, an ideal carrier system for BMPs has not yet been identified. The purpose of this study was to evaluate the osteogenic effect of a fibrin-fibronectin sealing system (FFSS) combined with beta-tricalcium phosphate (beta-TCP) as a carrier syst...

journal_title：Biomaterials

authors： Hong SJ,Kim CS,Han DK,Cho IH,Jung UW,Choi SH,Kim CK,Cho KS

更新日期：2006-07-01 00:00:00

abstract：:Construction of bio-mimetic well-organized three-dimensional (3D) tissue with various cells in vitro is one of the ultimate goals of tissue engineering. In particular, fabrication of vasculature in 3D tissue is one of the most important tasks in tissue engineering, because a vascular network is indispensable for almos...

journal_title：Biomaterials

authors： Muraoka M,Shimizu T,Itoga K,Takahashi H,Okano T

更新日期：2013-01-01 00:00:00

abstract：:The urgent needs of functional arterial replacements for curing the vascular system diseases have been proposed for many years. However, an ideal small-diameter vascular scaffold, which is nonthrombogenic, minimizes intimal hyperplasia, matches the mechanical properties of natural vessels, and supports neovascular tis...

journal_title：Biomaterials

authors： Han F,Jia X,Dai D,Yang X,Zhao J,Zhao Y,Fan Y,Yuan X

更新日期：2013-10-01 00:00:00

abstract：:Neural transplantation therapy using neural stem cells has received as potential treatments for neurodegenerative diseases. Indeed, this therapy is thought to be effective for replacement of degenerating neurons in restricted anatomical region. However, because injected neural stem cells integrate randomly into the ho...

journal_title：Biomaterials

authors： Kato-Negishi M,Tsuda Y,Onoe H,Takeuchi S

更新日期：2010-12-01 00:00:00