Abstract：
:Microfluidic paper-based analytical devices (µPADs) have provided a breakthrough in portable and low-cost point-of-care diagnostics. Despite their significant scope, the complexity of fabrication and reliance on expensive and sophisticated tools, have limited their outreach and possibility of commercialization. Herein, we report for the first time, a facile method to fabricate µPADs using a commonly available laser printer which drastically reduces the cost and complexity of fabrication. Toner ink is used to pattern the µPADs by printing, without modifying any factory configuration of the laser printer. Hydrophobic barriers are created by heating the patterned paper which melts the toner ink, facilitating its wicking into the cross-section of the substrate. Further, we demonstrate the utilization of the fabricated device by performing two assays. The proposed technique provides a versatile platform for rapid prototyping of µPADs with significant prospect in both developed and resource constrained region.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ghosh R,Gopalakrishnan S,Savitha R,Renganathan T,Pushpavanam Sdoi
10.1038/s41598-019-44455-1subject
Has Abstractpub_date
2019-05-27 00:00:00pages
7896issue
1issn
2045-2322pii
10.1038/s41598-019-44455-1journal_volume
9pub_type
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