One is Nothing without the Other: Theoretical and Empirical Analysis of Cell Growth and Cell Cycle Progression.

Abstract:

:Small, fast-growing bacteria make ideal subjects for genetic and quantitative analysis alike. Long the darling of theoreticians, efforts to understand the relationship between cell growth and cell cycle progression in bacterial systems have been propelled by modelers and empiricist in equal measure. Taking a historical approach, here we break down early work in this area, the impact it had on how the bacterial cell cycle is understood and interrogated, and changes brought by the advent of high-throughput techniques for the analysis of individual bacterial cells in culture.

journal_name

J Mol Biol

authors

Levin PA,Taheri-Araghi S

doi

10.1016/j.jmb.2019.04.004

subject

Has Abstract

pub_date

2019-05-17 00:00:00

pages

2061-2067

issue

11

eissn

0022-2836

issn

1089-8638

pii

S0022-2836(19)30186-X

journal_volume

431

pub_type

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