Abstract:
:TRPM family (Transient receptor potential channels, M for melastatin) is a group of intrinsic plasma membrane ion channels which are widely expressed throughout human body. It has been identified as a potent entry point of working desperate diseases out in a new way with newfangled ideas and safer technological means. In our review, we discussed the common and unique properties of TRPM family with the elaborate narrate in their overall structures, different states and the underlying activation mechanism. Thus, this review can help to consummate the limited work of TRPM family and provide novel therapeutic targets of certain diseases.
journal_name
Cell Calciumjournal_title
Cell calciumauthors
Chen Y,Zhang X,Yang T,Bi R,Huang Z,Ding H,Li J,Zhang Jdoi
10.1016/j.ceca.2019.02.011subject
Has Abstractpub_date
2019-05-01 00:00:00pages
75-79eissn
0143-4160issn
1532-1991pii
S0143-4160(19)30007-7journal_volume
79pub_type
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