Abstract:
:Mid-infrared quantum cascade lasers operating under external optical feedback and external periodic bias forcing are shown to exhibit a deterministic chaotic pattern composed of frequencies which are linked to the one of the forcing. Results also show that both the amplitude and the frequency of the forcing play a key role in the number of retrieved spikes per modulation period. These findings are of paramount importance for chaotic operation of quantum cascade lasers in applications such as optical countermeasure systems and secure atmospheric transmission lines, as well as for simulating neuronal systems and the communication between neurons due to sudden bursts.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Spitz O,Wu J,Carras M,Wong CW,Grillot Fdoi
10.1038/s41598-019-40861-7subject
Has Abstractpub_date
2019-03-14 00:00:00pages
4451issue
1issn
2045-2322pii
10.1038/s41598-019-40861-7journal_volume
9pub_type
杂志文章abstract::Fibril formation implies the conversion of a protein's native secondary structure and is associated with several neurodegenerative diseases. A better understanding of fibrillation inhibition and fibril dissection requires nanoscale molecular characterization of amyloid structures involved. Tip-enhanced Raman scatterin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39622
更新日期:2016-12-23 00:00:00
abstract:ABSTARCT:The relationship between chronic kidney disease (CKD), which is defined by declined estimated glomerular filtration rate (eGFR) and/or proteinuria, and asymptomatic intracranial arterial stenosis (ICAS) is largely unknown. We conducted a population-based, cross-sectional study by recruiting 5209 participants f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04549-0
更新日期:2017-07-04 00:00:00
abstract::Inference of the biological roles of lncRNAs in breast cancer development remains a challenge. Here, we analyzed RNA-seq data in tumor and normal breast tissue samples from 18 breast cancer patients and 18 healthy controls and constructed a functional lncRNA-mRNA co-expression network. We revealed two distinctive co-e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32731
更新日期:2016-09-06 00:00:00
abstract::Equine athletes have a pattern of exercise which is analogous to human athletes and the cardiovascular risks in both species are similar. Both species have a propensity for atrial fibrillation (AF), which is challenging to detect by ECG analysis when in paroxysmal form. We hypothesised that the proarrhythmic backgroun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63343-7
更新日期:2020-04-22 00:00:00
abstract::Complex systems displaying recurrent spike patterns are ubiquitous in nature. Understanding the organization of these patterns is a challenging task. Here we study experimentally the spiking output of a semiconductor laser with feedback. By using symbolic analysis we unveil a nontrivial organization of patterns, revea...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04696
更新日期:2014-04-15 00:00:00
abstract::As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past decade. On the other hand, recent advances in deep learning and transfer learning have shown significant potential in the quantitative medical imaging field, raising the research question of whethe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-80998-y
更新日期:2021-01-14 00:00:00
abstract::This study was aimed to investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in patients with prostate cancer (PCa). A meta-analysis including 14 publications (15 cohorts) with 16,266 patients was performed to evaluate the association between NLR and overall survival (OS), progression-free survival...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析,评审
doi:10.1038/srep22089
更新日期:2016-02-25 00:00:00
abstract::The interaction of (quasi)particles with a periodic potential arises in various domains of science and engineering, such as solid-state physics, chemical physics, and communication theory. An attractive test ground to investigate this interaction is represented by superconductors with artificial pinning sites, where m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14232-z
更新日期:2017-10-23 00:00:00
abstract::In the course of sample preparation for Next Generation Sequencing (NGS), DNA is fragmented by various methods. Fragmentation shows a persistent bias with regard to the cleavage rates of various dinucleotides. With the exception of CpG dinucleotides the previously described biases were consistent with results of the D...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65406-1
更新日期:2020-05-25 00:00:00
abstract::rag1 -/- zebrafish have been employed in immunological research as a useful immunodeficient vertebrate model, but with only fragmentary evidence for the lack of functional adaptive immunity. rag1-null zebrafish exhibit differences from their human and murine counterparts in that they can be maintained without any spec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08000-2
更新日期:2017-08-08 00:00:00
abstract::Parental age is increasing rapidly in many countries. Analysis of this potentially important influence on offspring well-being is hampered by strong secular trends and socioeconomic patterning and by a shortage of follow-up data for adult offspring. We used Swedish national data on up to 3,653,938 offspring to conside...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45278
更新日期:2017-03-27 00:00:00
abstract::Multi-atlas-based segmentation (MAS) methods have demonstrated superior performance in the field of automatic image segmentation, and label fusion is an important part of MAS methods. In this paper, we propose a label fusion method that incorporates pixel greyscale probability information. The proposed method combines...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54527-x
更新日期:2019-11-29 00:00:00
abstract::ATP depletion and succinate accumulation during ischemia lead to oxidative damage to mammalian organs upon reperfusion. In contrast, freshwater turtles survive weeks of anoxia at low temperatures without suffering from oxidative damage upon reoxygenation, but the mechanisms are unclear. To determine how turtles surviv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39836-5
更新日期:2019-02-26 00:00:00
abstract::Short chain fatty acids (SCFAs) produced by intestinal microbes mediate anti-inflammatory effects, but whether they impact on antimicrobial host defenses remains largely unknown. This is of particular concern in light of the attractiveness of developing SCFA-mediated therapies and considering that SCFAs work as inhibi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37944
更新日期:2016-11-29 00:00:00
abstract::Bacterial infection and sepsis are common complications of chronic kidney disease (CKD). A vicious cycle of increased gut permeability, endotoxemia, inadequate activation of the innate immune system and resulting innate immune dysfunction is hypothesized. We assessed endotoxemia, neutrophil function and its relation t...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep34534
更新日期:2016-10-04 00:00:00
abstract::Cell-to-cell heterogeneity is driven by stochasticity in intracellular reactions and the population dynamics. While these sources are usually studied separately, we develop an agent-based framework that accounts for both factors while tracking every single cell of a growing population. Apart from the common intrinsic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35927-x
更新日期:2019-01-24 00:00:00
abstract::Hepatic fibrosis is caused by exaggerated wound healing response to chronic injury, which eventually leads to hepatic cirrhosis. Differentiation of hepatic stellate cells (HSCs) to myofibroblast-like cells by inflammatory cytokines is the critical step in fibrosis. This step is accompanied by enlargement of the endopl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08703-6
更新日期:2017-08-11 00:00:00
abstract::Solar thermoelectric generators (STEGs), which are used for various applications, (particularly small size electronic devices), have optical concentration systems for high energy conversion efficiency. In this study, a refraction-assisted STEG (R-STEG) is designed based on phase-change materials. As the phase-change m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27913
更新日期:2016-06-10 00:00:00
abstract::Theileria annulata is a haemoprotozoan parasite that causes a cancer-like illness known as tropical theileriosis in cattle. In the course of analyzing the genetic diversity of T. annulata in Sri Lanka, we observed that merozoite-piroplasm surface antigen (tams1) and surface protein (tasp)-like gene sequences obtained ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52512-y
更新日期:2019-11-06 00:00:00
abstract::Lipid droplet (LD)-associated hydrolase (LDAH) is a newly identified LD protein abundantly expressed in tissues that predominantly store triacylglycerol (TAG). However, how LDAH regulates TAG metabolism remains unknown. We found that upon oleic acid loading LDAH translocalizes from the ER to newly formed LDs, and indu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02963-y
更新日期:2017-06-02 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-76567-4
更新日期:2020-11-05 00:00:00
abstract::An obstacle for precision improvement in quantum metrology is the information loss causing by the unavoidable interaction between probe system and environment. Quantum fluctuations are environment no system can be isolated from and it will make the precision of initial parameter estimation of the probe atom decrease w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00544-7
更新日期:2017-03-24 00:00:00
abstract::Considering the significance of mast cells (MCs) in the course of various physiological and pathological processes, and the pivotal role of endogenous molecules, i.e., cathelicidins and defensins as multifunctional modulators, the study examines the constitutive and cathelicidin LL-37/defensin hBD-2-induced expression...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30289-w
更新日期:2018-08-06 00:00:00
abstract::Cyclophilin A (CyPA), secreted by vascular smooth muscle cells in response to oxidative stress, is important in the pathogenesis of progressive peripheral arterial occlusion disease (PAOD), which is common among chronic kidney disease. We explored the prevalence of PAOD in Taiwan's elderly (≥ 65 years old) population ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09937
更新日期:2015-04-24 00:00:00
abstract::Nanospheres of lead (Pb) have recently been identified in zircon (ZrSiO4) with the potential to compromise the veracity of U-Pb age determinations. The key assumption that the determined age is robust against the effects of Pb mobility, as long as Pb is not lost from the zircon during subsequent geological events, is ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49882-8
更新日期:2019-09-23 00:00:00
abstract::Microglia are the resident phagocytic cells with various functions in the central nervous system, and the morphologies of microglia imply the different stages and functions. In optical nerve transection (ONT) model in the retina, the retrograde degeneration of retinal ganglion cells (RGCs) induces microglial activatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10788
更新日期:2015-06-02 00:00:00
abstract::Exendin-4 is a long acting glucagon-like peptide 1 (GLP-1) analogue that is an agonist for the GLP-1 receptor, a G-protein coupled receptor (GPCR). Exendin-4 is used to clinically improve glucose tolerance in diabetic patients due to its ability to enhance insulin secretion. In rodents, and possibly in humans, exendin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09898-4
更新日期:2017-08-22 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-66186-4
更新日期:2020-06-16 00:00:00
abstract::This retrospective study was undertaken to identify predictors for the development of hypocalcaemia even with prophylactic administration of calcium and vitamin D, and to help guide future strategies to improve the safety, efficacy, and QOL of patients receiving denosumab. Between January 2016 and February 2020, a tot...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80243-y
更新日期:2021-01-13 00:00:00
abstract::Rhegmatogenous retinal detachment (RRD) is an ophthalmic emergency, which usually requires prompt surgery to prevent further detachment and restore sensory function. Although several individual factors have been suggested, a systems level understanding of molecular pathomechanisms underlying this severe eye disorder i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80005-w
更新日期:2021-01-13 00:00:00