FOXE1 supports the tumor promotion of Gli2 on papillary thyroid carcinoma by the Wnt/β-catenin pathway.

abstract：:A number of different organs and tissues from untreated or endotoxin-injected mice were surveyed for their ability to produce conditioned medium that could induce differentiation of the myelomonocytic leukemic cell line WEHI-3B. All organs were able to do this but were much more effective from endotoxin-injected anima...

journal_title：Journal of cellular physiology

authors： Nicola NA,Metcalf D

更新日期：1981-11-01 00:00:00

abstract：:Liver fibrosis is a reversible wound-healing response that occurs after liver injury. NADPH oxidases (NOXs) and reactive oxygen species (ROS) which are expressed in hepatocytes (HCs), hepatic stellate cells (HSCs), and Kupffer cells (KCs) play an important role in the development of hepatic fibrosis. In in vitro studi...

journal_title：Journal of cellular physiology

authors： Gan D,Zhang W,Huang C,Chen J,He W,Wang A,Li B,Zhu X

更新日期：2018-10-01 00:00:00

abstract：:In vitro incubation of hepatocytes acutely isolated from adult male rats leads to a rapid conversion of the adrenergic activation of glycogenolysis from an alpha 1-receptor (alpha 1AR) to a beta 2-receptor (beta 2AR) mediated response within 4 h. In order to understand the underlying mechanism, we examined time-depend...

journal_title：Journal of cellular physiology

authors： Ishac EJ,Lazar-Wesley E,Kunos G

更新日期：1992-07-01 00:00:00

abstract：:Cell adhesion receptors, referred to as integrins, are recognized as key regulators of cellular processes including growth and differentiation. Integrins communicate with growth factor receptors (GFRs) to control specific cellular responses to stimuli originating in the extracellular environment. In this article, we r...

journal_title：Journal of cellular physiology

authors： Alam N,Goel HL,Zarif MJ,Butterfield JE,Perkins HM,Sansoucy BG,Sawyer TK,Languino LR

更新日期：2007-12-01 00:00:00

abstract：:The effects of kinin B1 receptor (B1 R) deletion were examined on femur bone regeneration in streptozotocin (STZ)-type 1 diabetes. Diabetes induction in wild-type C57/BL6 (WTC57BL6) mice led to decrease in body weight and hyperglycemia, compared to the non-diabetic group of the same strain. The lack of B1 R did not af...

journal_title：Journal of cellular physiology

authors： Cignachi NP,Pesquero JB,Oliveira RB,Etges A,Campos MM

更新日期：2015-12-01 00:00:00

abstract：:The cells responsible for the long-term in vitro generation of murine mast cells have been examined. Sequential analysis of all colony types obtained from cultures of spleen or bone marrow cells showed that only colonies derived from multipotential cells (mixed-erythroid colonies) or mast cell progenitors, contained c...

journal_title：Journal of cellular physiology

authors： Li CL,Johnson GR

更新日期：1984-10-01 00:00:00

abstract：:An in-depth understanding of circular RNAs (circRNAs) indicates that they are abundant in the eukaryotic transcriptome. Many circRNAs act as microRNA sponges; thus, they represent a new type of regulatory factor. However, the role of circRNA in colorectal cancer (CRC) remains largely unknown. Low circ_0021977 expressi...

journal_title：Journal of cellular physiology

authors： Lu C,Jiang W,Hui B,Rong D,Fu K,Dong C,Tang W,Cao H

更新日期：2020-03-01 00:00:00

abstract：:The extracellular matrix (ECM) physically supports cells and influences stem cell behaviour, modulating kinase-mediated signalling cascades. Cell-derived ECMs have emerged in bone regeneration as they reproduce physiological tissue-architecture and ameliorate mesenchymal stromal cell (MSC) properties. Titanium scaffol...

journal_title：Journal of cellular physiology

authors： Baroncelli M,Fuhler GM,van de Peppel J,Zambuzzi WF,van Leeuwen JP,van der Eerden BCJ,Peppelenbosch MP

更新日期：2019-03-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) cells are characterised by their extreme chemoresistance. The activity of multiple-drug resistance (MDR) transporters that extrude antitumor drugs from cells plays the most important role in this phenomenon. To date, the mechanism controlling the expression and activity of MDR transporter...

journal_title：Journal of cellular physiology

authors： Quezada C,Garrido W,Oyarzún C,Fernández K,Segura R,Melo R,Casanello P,Sobrevia L,San Martín R

更新日期：2013-03-01 00:00:00

abstract：:The temperature-sensitive (ts) Chinese hamster ovary (CHO) cell mutant tsH1 contains a thermolabile leucyl-tRNA synthetase. Upon incubation at the nonpermissive temperature of 39.5 degrees C, the enzyme became reversibly inhibited over a period of minutes, and the cells lost viability over a period of many hours. Howe...

journal_title：Journal of cellular physiology

authors： Vidair CA,Dewey WC

更新日期：1989-08-01 00:00:00

abstract：:Chick embryo fibroblasts were maintained at confluency for up to 35 days in medium containing 0.5% or 0.75% fetal bovine serum or 2.5% or 5.0% horse serum. At weekly intervals cells were subcultured and serially propagated in medium containing 10% FBS until their replicative lifespans were completed. The results showe...

journal_title：Journal of cellular physiology

authors： Nielsen PJ,Ryan JM

更新日期：1981-06-01 00:00:00

abstract：:Cultured bovine adrenocortical cells were previously shown to be functionally deficient in selenium and vitamin E when grown in medium supplemented with fetal bovine serum. In the present experiments, the lack of significant bioavailable amounts of selenium in the medium was demonstrated by the finding of only low lev...

journal_title：Journal of cellular physiology

authors： Hornsby PJ,Pearson DW,Autor AP,Aldern KA,Harris SE

更新日期：1985-04-01 00:00:00

abstract：:Experiments were conducted to determine the extent and variability of collagen degradation in human fetal lung fibroblasts. Cells were incubated with [14C]proline, and degradation was measured by determining the hydroxy[14C]proline in a low molecular weight fraction relative to total hydroxy[14C]proline. Average (basa...

journal_title：Journal of cellular physiology

authors： Bienkowski RS

更新日期：1984-10-01 00:00:00

abstract：:The beneficial effects of light-emitting diode (LED) irradiation have been reported in various pathologies, including cancer. However, its effect in pancreatic cancer cells remains unclear. Herein, we demonstrated that blue LED of 460 nm regulated pancreatic cancer cell proliferation and apoptosis by suppressing the e...

journal_title：Journal of cellular physiology

authors： Kim YM,Ko SH,Shin YI,Kim Y,Kim T,Jung J,Lee SY,Kim NG,Park KJ,Ryu JH

更新日期：2021-02-01 00:00:00

abstract：:Several proteases and their specific inhibitors modulate the interdependent processes of cell migration and matrix proteolysis as part of the global program of trauma repair. Expression of plasminogen activator inhibitor type-1 (PAI-1), a serine protease inhibitor (SERPIN) important in the control of barrier proteolys...

journal_title：Journal of cellular physiology

authors： Providence KM,Higgins PJ

更新日期：2004-08-01 00:00:00

abstract：:The signal transducer and activator of transcription (Stat5) funnels extracellular signals of cytokines, hormones, and growth factors into transcriptional activity in the mammary gland. Postnatal development and functionality of this tissue is synchronized with the reproductive cycle. Consequently, Stat5 involvement i...

journal_title：Journal of cellular physiology

authors： Barash I

更新日期：2006-11-01 00:00:00

abstract：:Ovarian cancer (OC) is a fatal cancer in women, mainly due to its aggressive nature and poor survival rate. The lncRNA-miRNA-mRNA (long noncoding RNA-microRNA-messenger RNA) interaction is promising biomarkers for the improving prognosis of OC. Therefore, we explored the regulatory mechanism of WDFY3-AS2/miR-18a/RORA ...

journal_title：Journal of cellular physiology

authors： Li W,Ma S,Bai X,Pan W,Ai L,Tan W

更新日期：2020-02-01 00:00:00

abstract：:Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to Clostridium perfringens enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detached. Nearly half of the cells were non...

journal_title：Journal of cellular physiology

authors： McClane BA,McDonel JL

更新日期：1979-05-01 00:00:00

abstract：:Acetylcholine (ACh) protected against cardiac injury via promoting autophagy and mitochondrial biogenesis, however, the involvement of mitophagy in ACh-elicited cardioprotection remains unknown. In the present study, H9c2 cardiomyocytes were subjected to hypoxia/reoxygenation (H/R) and ACh treatment during reoxygenati...

journal_title：Journal of cellular physiology

authors： Sun L,Zhao M,Yang Y,Xue RQ,Yu XJ,Liu JK,Zang WJ

更新日期：2016-05-01 00:00:00

abstract：:The poor prognosis of pancreatic cancer patients using currently available therapies mandates novel therapeutics that combine anti-neoplastic potency with toxicity-minimizing cancer specificity. Employing an overlapping pathway screen to identify genes exhibiting coordinated expression as a consequence of terminal cel...

journal_title：Journal of cellular physiology

authors： Chan I,Lebedeva IV,Su ZZ,Sarkar D,Valerie K,Fisher PB

更新日期：2008-05-01 00:00:00

abstract：:Indirect evidence for the presence of a growth inhibitor in normal human fibroblasts has been obtained previously; the inhibitory activity has been found associated with crude cell extracts, but the molecule responsible for the growth inhibition has never been isolated. We have isolated a glycopeptide fraction from hu...

journal_title：Journal of cellular physiology

authors： Macieira-Coelho A,Söderberg A

更新日期：1993-01-01 00:00:00

abstract：:The oxygen dependence of hepatic cellular respiration was studied by employing simultaneous organ spectrophotometry of cytochromes and hemoglobin, the latter used as an intrasinusoidal optical oxygen probe. The Km of cytochrome aa3 for oxygen was found to be 6.8 microM in the isolated perfused liver and 0.3 microM in ...

journal_title：Journal of cellular physiology

authors： Kekonen EM,Jauhonen VP,Hassinen IE

更新日期：1987-10-01 00:00:00

abstract：:Podocyte injury is a critical factor for the initiation and progression of diabetic kidney disease (DKD). However, the underlying mechanisms of podocyte injury in DKD have not been completely elucidated. Studies suggested that intracellular cholesterol accumulation was correlated with podocyte injury, but the cause of...

journal_title：Journal of cellular physiology

authors： Hu J,Yang Q,Chen Z,Liang W,Feng J,Ding G

更新日期：2019-12-01 00:00:00

abstract：:Overexpression of IGF-1 in C2C12 myoblasts causes hypertrophy when myoblasts fuse to form myotubes, a response that requires elevated intracellular calcium. We show that myoblasts contain a store-operated Ca2+ channel (SOCC) whose activity is enhanced with IGF-1 overexpression. A membrane protein, CD20, can cause Ca2+...

journal_title：Journal of cellular physiology

authors： Ju YK,Wu MJ,Chaulet H,Marciniec T,Graham RM,Allen DG

更新日期：2003-10-01 00:00:00

abstract：:We recently reported that the growth of normal rat pleural mesothelial cells (RPMCs) is inhibited by conditioned media from either in vivo or in vitro transformed RPMCs. In this study we report that the growth of normal RPMCs is inhibited by epidermal growth factor (EGF). This was demonstrated by using three methods o...

journal_title：Journal of cellular physiology

authors： Van der Meeren A,Levy F,Renier A,Katz A,Jaurand MC

更新日期：1990-07-01 00:00:00

abstract：:Somatic cell hybrids between either normal human fibroblasts, phenotypically normal mouse fibroblasts or mouse peritoneal macrophages and HT1080 human diploid fibrosarcoma cells were studied for their ability to form tumors in nude mice. The results of this study indicate that tumorigenic behavior is expressed as a do...

journal_title：Journal of cellular physiology

authors： Croce CM,Barrick J,Linnenbach A,Koprowski H

更新日期：1979-06-01 00:00:00

abstract：:Two transport systems for neutral amino acids have been characterised in LLC-PK, cells. The first, which transports alanine in a sodium-dependent manner, also mediates alanine exchange and is perferentially inhibited by serine, cysteine, and alpha-amino-n-butyric acid. This system resembles the ASC system in Ehrlich a...

journal_title：Journal of cellular physiology

authors： Sepúlveda FV,Pearson JD

更新日期：1982-08-01 00:00:00

abstract：:Our understanding of the mechanism of cell fate transition during the direct reprogramming of fibroblasts into various central nervous system (CNS) neural cell types has been limited by the lack of a comprehensive analysis on generated cells, independently and in comparison with other CNS neural cell types. Here, we a...

journal_title：Journal of cellular physiology

authors： Khazaei N,Rastegar-Pouyani S,O'Toole N,Wee P,Mohammadnia A,Yaqubi M

更新日期：2018-04-01 00:00:00

abstract：:Despite being densely packed with chromatin, nuclear bodies and a nucleoskeletal network, the nucleus is a remarkably dynamic organelle. Chromatin loops form and relax, RNA transcripts and transcription factors move diffusively, and nuclear bodies move. We show here that RNA splicing speckled domains (splicing speckle...

journal_title：Journal of cellular physiology

authors： Zhang Q,Kota KP,Alam SG,Nickerson JA,Dickinson RB,Lele TP

更新日期：2016-06-01 00:00:00

abstract：:Recently, ATP has gained much interest as an extracellular messenger involved in the communication of calcium signals between cells. The mechanism of ATP release is, however, still a matter of debate. In the present study we investigated the possible contribution of connexin hemichannels or ion channels in the release...

journal_title：Journal of cellular physiology

authors： Braet K,Aspeslagh S,Vandamme W,Willecke K,Martin PE,Evans WH,Leybaert L

更新日期：2003-11-01 00:00:00