Evolution, Composition and Regulation of Supernumerary B Chromosomes.

abstract：:Small RNAs play an important role in regulating plant responses to abiotic stress. Depending on the method of salt application, whether sudden or gradual, plants may experience either salt shock or salt stress, respectively. In this study, small RNA expression in response to salt shock and long-term salt stress in par...

journal_title：Genes

authors： Yin Z,Han X,Li Y,Wang J,Wang D,Wang S,Fu X,Ye W

更新日期：2017-12-05 00:00:00

abstract：:Epigenetic modifications are a mechanism conveying environmental information to subsequent generations via parental germ lines. Research on epigenetic responses to environmental changes in wild mammals has been widely neglected, as well as studies that compare responses to changes in different environmental factors. H...

journal_title：Genes

authors： Weyrich A,Lenz D,Fickel J

更新日期：2018-12-21 00:00:00

abstract：:DNA damage leads to genome instability by interfering with DNA replication. Cells possess several damage bypass pathways that mitigate the effects of DNA damage during replication. These pathways include translesion synthesis and template switching. These pathways are regulated largely through post-translational modif...

journal_title：Genes

authors： Ripley BM,Gildenberg MS,Washington MT

更新日期：2020-01-29 00:00:00

abstract：:Spiders often produce multiple types of silk, each with unique properties suiting them to certain tasks and biological functions. Orb-weaver spiders can generate more than six types of silk fibroins, with pyriform silk used to form attachment discs, adhering silk to other surfaces and substances. The unique higher-ord...

journal_title：Genes

authors： Wang K,Wen R,Jia Q,Liu X,Xiao J,Meng Q

更新日期：2019-06-03 00:00:00

abstract：:(1) Background: Autoimmune thyroid diseases (AITDs) are female predominant and much attention has been focused on G protein-coupled receptor 174 (GPR174) and integral membrane protein 2A (ITM2A) on the X chromosome as Grave's disease (GD) susceptible locus. (2) Methods: We genotyped four single nucleotide polymorphism...

journal_title：Genes

authors： Cho WK,Shin HR,Lee NY,Kim SK,Ahn MB,Baek IC,Kim TG,Suh BK

更新日期：2020-07-27 00:00:00

abstract：:Small and isolated populations are subject to the loss of genetic variation as a consequence of inbreeding and genetic drift, which in turn, can affect the fitness and long-term viability of populations. Translocations can be used as an effective conservation tool to combat this loss of genetic diversity through estab...

journal_title：Genes

authors： Rick K,Ottewell K,Lohr C,Thavornkanlapachai R,Byrne M,Kennington WJ

更新日期：2019-10-28 00:00:00

abstract：:Xeroderma pigmentosum group C (XPC) is a key component of the nucleotide excision repair (NER) pathway. Dysfunctional XPC protein may impair NER-mediated DNA repair capacity and further lead to genomic instability and carcinogenesis. Two common nonsynonymous polymorphisms in the XPC gene, Lys939Gln (rs2228001 A > C) a...

journal_title：Genes

authors： Hua RX,Zhu J,Jiang DH,Zhang SD,Zhang JB,Xue WQ,Li XZ,Zhang PF,He J,Jia WH

更新日期：2016-09-24 00:00:00

abstract：:Fruit set is the earliest phase of fruit growth and represents the onset of ovary growth after successful fertilization. In parthenocarpy, fruit formation is less affected by environmental factors because it occurs in the absence of pollination and fertilization, making parthenocarpy a highly desired agronomic trait. ...

journal_title：Genes

authors： Molesini B,Dusi V,Pennisi F,Pandolfini T

更新日期：2020-11-30 00:00:00

abstract：:Tetralin (1,2,3,4-tetrahydonaphthalene) is a recalcitrant compound that consists of an aromatic and an alicyclic ring. It is found in crude oils, produced industrially from naphthalene or anthracene, and widely used as an organic solvent. Its toxicity is due to the alteration of biological membranes by its hydrophobic...

journal_title：Genes

authors： Floriano B,Santero E,Reyes-Ramírez F

更新日期：2019-05-06 00:00:00

abstract：:The etiology and reasons underlying the ethnic disparities in systemic sclerosis (SSc) remain unknown. African Americans are disproportionally affected by SSc and yet are underrepresented in research. The aim of this study was to comprehensively investigate the association of DNA methylation levels with SSc in dermal ...

journal_title：Genes

authors： Baker Frost D,da Silveira W,Hazard ES,Atanelishvili I,Wilson RC,Flume J,Day KL,Oates JC,Bogatkevich GS,Feghali-Bostwick C,Hardiman G,Ramos PS

更新日期：2021-01-20 00:00:00

abstract：:Acquisition of mobile elements by horizontal gene transfer can play a major role in bacterial adaptation and genome evolution by providing traits that contribute to bacterial fitness. However, gaining foreign DNA can also impose significant fitness costs to the host bacteria and can even produce detrimental effects. T...

journal_title：Genes

authors： Piña-Iturbe A,Suazo ID,Hoppe-Elsholz G,Ulloa-Allendes D,González PA,Kalergis AM,Bueno SM

更新日期：2020-01-29 00:00:00

abstract：BACKGROUND:Large-scale screening of drug sensitivity on cancer cell models can mimic in vivo cellular behavior providing wider scope for biological research on cancer. Since the therapeutic effect of a single drug or drug combination depends on the individual patient's genome characteristics and cancer cells integratio...

journal_title：Genes

authors： Cheng L,Majumdar A,Stover D,Wu S,Lu Y,Li L

更新日期：2020-02-28 00:00:00

abstract：:Bupleurum falcatum, which belongs to the family Apiaceae, has long been applied for curative treatments, especially as a liver tonic, in herbal medicine. The chloroplast (cp) genome has been an ideal model to perform the evolutionary and comparative studies because of its highly conserved features and simple structure...

journal_title：Genes

authors： Shin DH,Lee JH,Kang SH,Ahn BO,Kim CK

更新日期：2016-05-13 00:00:00

abstract：:Vitellogenin receptors (VgRs) play critical roles in egg formation by transporting vitellogenin (Vg) into oocytes in insects. Although the function of VgR in insects is well studied, the transcriptional regulation of this gene is still unclear. Here, we cloned the promoter of the VgR gene from Bombyx mori (BmVgR), and...

journal_title：Genes

authors： Shen G,Chen E,Ji X,Liu L,Liu J,Hua X,Li D,Xiao Y,Xia Q

更新日期：2020-04-06 00:00:00

abstract：:Trees and their seeds regulate their germination, growth, and reproduction in response to environmental stimuli. These stimuli, through signal transduction, trigger transcription factors that alter the expression of various genes leading to the unfolding of the genetic program. A regulon is conceptually defined as a s...

journal_title：Genes

authors： Xia X

更新日期：2020-08-25 00:00:00

abstract：:In addition to its wide geographical distribution, osteoglossiform fishes represent one of the most ancient freshwater teleost lineages; making it an important group for systematic and evolutionary studies. These fishes had a Gondwanan origin and their past distribution may have contributed to the diversity present in...

journal_title：Genes

authors： Barby FF,Ráb P,Lavoué S,Ezaz T,Bertollo LAC,Kilian A,Maruyama SR,Aguiar de Oliveira E,Artoni RF,Santos MH,Ilesanmi Jegede O,Hatanaka T,Tanomtong A,Liehr T,Cioffi MB

更新日期：2018-06-19 00:00:00

abstract：:In the years since the first complete human genome sequence was reported, there has been a rapid development of technologies to facilitate high-throughput sequence analysis of DNA (termed "next-generation" sequencing). These novel approaches to DNA sequencing offer the promise of complete genomic analysis at a cost fe...

journal_title：Genes

authors： Anderson MW,Schrijver I

更新日期：2010-05-25 00:00:00

abstract：BACKGROUND:Radiation induces DNA double-strand breaks (DSBs), and chromosome aberrations (CA) form during the DSBs repair process. Several methods have been used to model the repair kinetics of DSBs including the bi-exponential model, i.e., N(t) = N1exp(-t/τ1) + N2exp(-t/τ2), where N(t) is the number of breaks at time ...

journal_title：Genes

authors： Plante I,Slaba T,Shavers Z,Hada M

更新日期：2019-11-16 00:00:00

abstract：:The continuous development of new genotyping technologies requires awareness of their potential advantages and limitations concerning utility for pharmacogenomics (PGx). In this review, we provide an overview of technologies that can be applied in PGx research and clinical practice. Most commonly used are single nucle...

journal_title：Genes

authors： van der Lee M,Kriek M,Guchelaar HJ,Swen JJ

更新日期：2020-12-04 00:00:00

abstract：:The MinION sequencer has made in situ sequencing feasible in remote locations. Following our initial demonstration of its high performance off planet with Earth-prepared samples, we developed and tested an end-to-end, sample-to-sequencer process that could be conducted entirely aboard the International Space Station (...

journal_title：Genes

authors： Burton AS,Stahl SE,John KK,Jain M,Juul S,Turner DJ,Harrington ED,Stoddart D,Paten B,Akeson M,Castro-Wallace SL

更新日期：2020-01-09 00:00:00

abstract：:Despite the extensive research conducted in recent decades, the molecular mechanisms underlying major depressive disorder (MDD) and relative evidence-based treatments remain unclear. Various hypotheses have been successively proposed, involving different biological systems. This narrative review aims to critically ill...

journal_title：Genes

authors： Maffioletti E,Minelli A,Tardito D,Gennarelli M

更新日期：2020-09-18 00:00:00

abstract：:Shewanella oneidensis MR-1 can transfer electrons from the intracellular environment to the extracellular space of the cells to reduce the extracellular insoluble electron acceptors (Extracellular Electron Transfer, EET). Benefiting from this EET capability, Shewanella has been widely used in different areas, such as ...

journal_title：Genes

authors： Ding D,Sun X

更新日期：2018-01-16 00:00:00

abstract：:Prader-Willi syndrome (PWS) is a complex multisystemic condition caused by a lack of paternal expression of imprinted genes from the 15q11.2-q13 region. Limited literature exists on the association between molecular classes, growth hormone use, and the prevalence of psychiatric phenotypes in PWS. In this study, we ana...

journal_title：Genes

authors： Montes AS,Osann KE,Gold JA,Tamura RN,Driscoll DJ,Butler MG,Kimonis VE

更新日期：2020-10-23 00:00:00

abstract：:Listeria monocytogenes is a major human foodborne pathogen that is prevalent in the natural environment and has a high case fatality rate. Whole genome sequencing (WGS) analysis has emerged as a valuable methodology for the classification of L. monocytogenes isolates and the identification of virulence islands that ma...

journal_title：Genes

authors： Hilliard A,Leong D,O'Callaghan A,Culligan EP,Morgan CA,DeLappe N,Hill C,Jordan K,Cormican M,Gahan CGM

更新日期：2018-03-20 00:00:00

abstract：:Transfer RNAs (tRNAs) are essential adaptors that mediate translation of the genetic code. These molecules undergo a variety of post-transcriptional modifications, which expand their chemical reactivity while influencing their structure, stability, and functionality. Chemical modifications to tRNA ensure translational...

journal_title：Genes

authors： Edwards AM,Addo MA,Dos Santos PC

更新日期：2020-08-07 00:00:00

abstract：:Juvenile open angle glaucoma (JOAG), which is an uncommon form of primary open angle glaucoma, is a clinically and genetically heterogeneous disorder. We report on a family with a recessively inherited form of JOAG. The proband has a superior and an inferior never fiber layer thinning in both the eyes and the nasal vi...

journal_title：Genes

authors： Saeedi O,Yousaf S,Tsai J,Palmer K,Riazuddin S,Ahmed ZM

更新日期：2018-10-30 00:00:00

abstract：:Background: The C34T polymorphism (rs 17602729) in adenosine monophosphate deaminase 1 gene (AMPD1) is associated with muscular energy metabolism in exercise. However, the role of its potential modifying impact on exercise-induced changes in obesity related parameters is unknown. The aim of the study was to determine ...

journal_title：Genes

authors： Leońska-Duniec A,Maculewicz E,Humińska-Lisowska K,Maciejewska-Skrendo A,Leźnicka K,Cięszczyk P,Sawczuk M,Trybek G,Wilk M,Lepionka W,Ficek K

更新日期：2020-05-16 00:00:00

abstract：:In angiosperms, meiotic failure coupled with the formation of genetically unreduced gametophytes in ovules (apomeiosis) constitute major components of gametophytic apomixis. These aberrant developmental events are generally thought to be caused by mutation. However, efforts to locate the responsible mutations have fai...

journal_title：Genes

authors： Mateo de Arias M,Gao L,Sherwood DA,Dwivedi KK,Price BJ,Jamison M,Kowallis BM,Carman JG

更新日期：2020-12-02 00:00:00

abstract：:Biallelic PIGT variants were previously reported in seven patients from three families with Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 (MCAHS3), characterized by epileptic encephalopathy, hypotonia, global developmental delay/intellectual disability, cerebral and cerebellar atrophy, craniofacial dysmo...

journal_title：Genes

authors： Skauli N,Wallace S,Chiang SC,Barøy T,Holmgren A,Stray-Pedersen A,Bryceson YT,Strømme P,Frengen E,Misceo D

更新日期：2016-11-29 00:00:00

abstract：:Gruiformes is a group with phylogenetic issues. Recent studies based on mitochondrial and genomic DNA have proposed the existence of a core Gruiformes, consisting of five families: Heliornithidae, Aramidae, Gruidae, Psophiidae and Rallidae. Karyotype studies on these species are still scarce, either by conventional st...

journal_title：Genes

authors： Furo IO,Kretschmer R,O'Brien PCM,Pereira JC,Ferguson-Smith MA,de Oliveira EHC

更新日期：2020-03-13 00:00:00