Abstract:
:The sudden onset of a face image leads to a prominent face-selective response in human scalp electroencephalographic (EEG) recordings, peaking 170 ms after stimulus onset at occipito-temporal (OT) scalp sites: the N170 (or M170 in magnetoencephalography). According to a widely held view, the main cortical source of the N170 lies in the fusiform gyrus (FG), whereas the posteriorly located inferior occipital gyrus (IOG) would rather generate earlier face-selective responses. Here, we report neural responses to upright and inverted faces recorded in a unique patient using multicontact intracerebral electrodes implanted in the right IOG and in the OT sulcus above the right lateral FG (LFG). Simultaneous EEG recordings on the scalp identified the N170 over the right OT scalp region. The latency and amplitude of this scalp N170 were correlated at the single-trial level with the N170 recorded in the lateral IOG, close to the scalp lateral occipital surface. In addition, a positive component maximal around the latency of the N170 (a P170) was prominent above the internal LFG, whereas this region typically generates an N170 (or "N200") over its external/ventral surface. This suggests that electrophysiological responses in the LFG manifest as an equivalent dipole oriented mostly along the vertical axis with likely minimal projection to the lateral OT scalp region. Altogether, these observations provide evidence that the IOG is a major cortical generator of the face-selective scalp N170, qualifying the potential contribution of the FG and questioning a strict serial spatiotemporal organization of the human cortical face network.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Jacques C,Jonas J,Maillard L,Colnat-Coulbois S,Koessler L,Rossion Bdoi
10.1002/hbm.24455subject
Has Abstractpub_date
2019-04-01 00:00:00pages
1403-1418issue
5eissn
1065-9471issn
1097-0193journal_volume
40pub_type
杂志文章abstract::Few studies have examined the neural correlates of emotion regulation across adolescence and young adulthood. Existing studies of cognitive reappraisal indicate that improvements in regulatory efficiency may develop linearly across this period, in accordance with maturation of prefrontal cortical systems. However, the...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22905
更新日期:2016-01-01 00:00:00
abstract::Adverse childhood experiences (ACEs) have been acknowledged as risk factors for increased mental health complications in adulthood, specifically increasing susceptibility to developing psychopathology upon exposure to trauma. Yet, little is known regarding the impact of mild ACEs on highly functioning population. In t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25246
更新日期:2021-02-15 00:00:00
abstract::The resting state default mode network (DMN) has been shown to characterize a number of neurological and psychiatric disorders. Evidence suggests an underlying genetic basis for this network and hence could serve as potential endophenotype for these disorders. Heritability is a defining criterion for endophenotypes. T...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22446
更新日期:2014-08-01 00:00:00
abstract::In addition to its role in visuospatial navigation and the generation of spatial representations, in recent years, the hippocampus has been proposed to support perceptual processes. This is especially the case where high-resolution details, in the form of fine-grained relationships between features such as angles betw...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24865
更新日期:2020-04-01 00:00:00
abstract::Impairment in controlled semantic association is a central feature of schizophrenia, and the goal of the current functional magnetic resonance imaging study was to identify the neural correlates of this impairment. Thirty people with schizophrenia and 30 healthy age- and gender-matched control subjects performed a tas...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22820
更新日期:2015-08-01 00:00:00
abstract::Rasagiline is a monoamine oxidase type B inhibitor that possesses no amphetamine-like properties, and provides symptomatic relief in early and late stages of Parkinson's disease (PD). Data in animal models of PD suggest that chronic administration of rasagiline is associated with structural changes in the substantia n...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23213
更新日期:2016-08-01 00:00:00
abstract::This study investigates the (re-)organization of somatosensory functions following early brain lesions. Using functional magnetic resonance imaging (fMRI), passive hand movement was studied. Transcranial magnetic stimulation (TMS) and magnetoencephalography (MEG) were used as complementary methods. fMRI data was analy...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20545
更新日期:2009-03-01 00:00:00
abstract::Irritability and nonviolent aggression are common behavioral features across the population, yet there is limited neurobiological research into subclinical phenotypes representing the lower edge of a symptom continuum ranging from slight irritability to criminal violence. We studied brain structural correlates of irri...
journal_title:Human brain mapping
pub_type: 杂志文章,多中心研究
doi:10.1002/hbm.23824
更新日期:2017-12-01 00:00:00
abstract::Task-based functional neuroimaging methods are increasingly being used to identify biomarkers of treatment response in psychiatric disorders. To facilitate meaningful interpretation of neural correlates of tasks and their potential changes with treatment over time, understanding the reliability of the blood-oxygen-lev...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24883
更新日期:2020-04-15 00:00:00
abstract::The functional organization of the human brain consists of a high degree of connectivity between interhemispheric homologous regions. The degree of homotopic organization is known to vary across the cortex and homotopic connectivity is high in regions that share cross-hemisphere structural connections or are activated...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23214
更新日期:2016-08-01 00:00:00
abstract::Mental calculation is a complex mental procedure involving a frontoparietal network of brain regions. Functional MRI (fMRI) studies have revealed interesting characteristics of these regions, but the precise function of some areas remains elusive. In the present study, we used electrocorticographic (ECoG) recordings t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22593
更新日期:2014-12-01 00:00:00
abstract::Transcranial magnetic stimulation (TMS) during positron emission tomography (PET) is a novel technique for in vivo measurements of connectivity and excitability of the human cerebral cortex. Here we describe tools that allow investigators to position the stimulating coil over a target region and to verify the actual p...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract::Gait disturbances, including freezing of gait, are frequent and disabling symptoms of Parkinson's disease. They often respond poorly to dopaminergic treatments. Although recent studies have shed some light on their neural correlates, their modulation by dopaminergic treatment remains quite unknown. Specifically, the i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22679
更新日期:2015-03-01 00:00:00
abstract::The anterior limb of the internal capsule (ALIC) is an important locus of frontal-subcortical fiber tracts involved in cognitive and limbic feedback loops. However, the structural organization of its component fiber tracts remains unclear. Therefore, although the ALIC is a promising target for various neurosurgical pr...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23815
更新日期:2017-12-01 00:00:00
abstract::Brain plasticity and memory formation depend on the expression of a large number of genes. This relationship had been studied using several experimental approaches and researchers have identified genes regulating plasticity through a variety of mechanisms. Despite this effort, a great deal remains unknown regarding th...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22592
更新日期:2014-12-01 00:00:00
abstract::The framework of assimilation and accommodation has been proposed to explain the brain mechanisms supporting second language reading acquisition (Perfetti et al. [2007]: Bilingual Lang Cogn 10:131). Assimilation refers to using the procedures of the native language network in the acquisition of a new writing system, w...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22904
更新日期:2015-10-01 00:00:00
abstract::Previous studies on crossmodal spatial orienting typically used simple and stereotyped stimuli in the absence of any meaningful context. This study combined computational models, behavioural measures and functional magnetic resonance imaging to investigate audiovisual spatial interactions in naturalistic settings. We ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22276
更新日期:2014-04-01 00:00:00
abstract::Active motor functional magnetic resonance imaging (fMRI) studies have shown that pediatric multiple sclerosis (MS) patients have a strictly lateralized pattern of activations and a preserved functional connectivity (FC) within the motor system when compared to age-matched healthy controls. However, it is still not cl...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22469
更新日期:2014-08-01 00:00:00
abstract::Functional imaging studies consistently find that emotional stimuli activate the posterior cingulate cortex, a region that appears to have memory-related functions. However, prior imaging studies have not controlled for non-emotional stimulus features that might activate this region by engaging memory processes unrela...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10075
更新日期:2003-01-01 00:00:00
abstract::Most of the previous task functional magnetic resonance imaging (fMRI) studies found abnormalities in distributed brain regions in mild cognitive impairment (MCI) and Alzheimer's disease (AD), and few studies investigated the brain network dysfunction from the system level. In this meta-analysis, we aimed to examine b...
journal_title:Human brain mapping
pub_type: 杂志文章,meta分析,评审
doi:10.1002/hbm.22689
更新日期:2015-03-01 00:00:00
abstract::Action observation leads to the automatic activation of the corresponding motor representation in the observer through "mirror-matching." This constitutes a "shared representational system," which is thought to subserve social understanding by motor simulation. However, it is unclear how these shared representations c...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20800
更新日期:2009-11-01 00:00:00
abstract::Investigations of the neural correlates of face recognition have typically used old/new paradigms where subjects learn to recognize new faces or identify famous faces. Familiar faces, however, include one's own face, partner's and parents' faces. Using event-related fMRI, we examined the neural correlates of these per...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20646
更新日期:2009-07-01 00:00:00
abstract::Previous structural and functional neuroimaging studies have implicated distributed brain regions and networks in depression. However, there are no robust imaging biomarkers that are specific to depression, which may be due to clinical heterogeneity and neurobiological complexity. A dimensional approach and fusion of ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24802
更新日期:2020-01-01 00:00:00
abstract::Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed a...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.25029
更新日期:2020-05-18 00:00:00
abstract::Imagination and creative cognition are often associated with the brain's default network (DN). Recent evidence has also linked cognitive control systems to performance on tasks involving imagination and creativity, with a growing number of studies reporting functional interactions between cognitive control and DN regi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23884
更新日期:2018-02-01 00:00:00
abstract::In this study we demonstrate that the pattern of an amygdala-centric network contributes to individual differences in trait anxiety. Individual differences in trait anxiety were predicted using maximum likelihood estimates of amygdala structural connectivity to multiple brain targets derived from diffusion-tensor imag...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22952
更新日期:2015-12-01 00:00:00
abstract::It has been suggested that in humans the mirror neuron system provides a neural substrate for imitation behaviour, but the relative contributions of different brain regions to the imitation of manual actions is still a matter of debate. To investigate the role of the mirror neuron system in imitation we used fMRI to e...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20938
更新日期:2010-09-01 00:00:00
abstract::The new clinically available arterial spin labeling (ASL) perfusion imaging sequences present some advantages relatively to the commonly used blood oxygen level-dependent (BOLD) method for functional brain studies using magnetic resonance imaging (MRI). In particular, regional cerebral blood flow (CBF) changes are tho...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/hbm.21418
更新日期:2013-01-01 00:00:00
abstract::The goal of this study was to determine the linearity of the blood oxygen level-dependent (BOLD) response, as measured by functional magnetic resonance imaging (fMRI), in category-selective regions of human visual cortex. We defined regions of the temporal lobe that were selective to faces (fusiform face area, FFA) an...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20694
更新日期:2009-08-01 00:00:00
abstract::This study constructs a rat brain T2 -weighted magnetic resonance imaging template including olfactory bulb and a compatible digital atlas. The atlas contains 624 carefully delineated brain structures based on the newest (2005) edition of rat brain atlas by Paxinos and Watson. An automated procedure, as an SPM toolbox...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21511
更新日期:2013-06-01 00:00:00