Connectivity-based parcellation of the anterior limb of the internal capsule.


:The anterior limb of the internal capsule (ALIC) is an important locus of frontal-subcortical fiber tracts involved in cognitive and limbic feedback loops. However, the structural organization of its component fiber tracts remains unclear. Therefore, although the ALIC is a promising target for various neurosurgical procedures for psychiatric disorders, more precise understanding of its organization is required to optimize target localization. Using diffusion tensor imaging (DTI) collected on healthy subjects by the Human Connectome Project (HCP), we generated parcellations of the ALIC by dividing it according to structural connectivity to various frontal regions. We then compared individuals' parcellations to evaluate the ALIC's structural consistency. All 40 included subjects demonstrated a posterior-superior to anterior-inferior axis of tract organization in the ALIC. Nonetheless, subdivisions of the ALIC were found to vary substantially, as voxels in the average parcellation were accurately assigned for a mean of only 66.2% of subjects. There were, however, some loci of consistency, most notably in the region maximally connected to orbitofrontal cortex. These findings clarify the highly variable organization of the ALIC and may represent a tool for patient-specific targeting of neuromodulation. Hum Brain Mapp 38:6107-6117, 2017. © 2017 Wiley Periodicals, Inc.


Hum Brain Mapp


Human brain mapping


Nanda P,Banks GP,Pathak YJ,Sheth SA




Has Abstract


2017-12-01 00:00:00












  • Thalamocortical sensorimotor circuit in multiple sclerosis: an integrated structural and electrophysiological assessment.

    abstract::Demyelination and axonal damage are pathologic hallmarks of multiple sclerosis (MS), leading to loss of neuronal synchronization, functional disconnection amongst brain relays, and clinical sequelae. To investigate these properties, the primary component of the sensorimotor network was analyzed in mildly disabled Rela...

    journal_title:Human brain mapping

    pub_type: 杂志文章,随机对照试验


    authors: Dell'Acqua ML,Landi D,Zito G,Zappasodi F,Lupoi D,Rossini PM,Filippi MM,Tecchio F

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  • Spontaneous blood oxygenation level-dependent fMRI signal is modulated by behavioral state and correlates with evoked response in sensorimotor cortex: a 7.0-T fMRI study.

    abstract::Synchrony measurements of spontaneous low-frequency blood oxygenation level-dependent (BOLD) fluctuations are increasingly being used to investigate spatial regions of functional connectivity. Although information regarding BOLD-BOLD synchrony between different regions is frequently reported, the relationship between ...

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  • Data-driven modeling of phase interactions between spontaneous MEG oscillations.

    abstract:OBJECTIVE:Synchronization between distributed rhythms in the brain is commonly assessed by estimating the synchronization strength from simultaneous measurements. This approach, however, does not elucidate the phase dynamics that underlies synchronization. For this, an explicit dynamical model is required. Based on the...

    journal_title:Human brain mapping

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    authors: Hindriks R,Bijma F,van Dijk BW,Stam CJ,van der Werf YY,van Someren EJ,de Munck JC,van der Vaart AW

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    pub_type: 杂志文章


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    更新日期:2018-12-01 00:00:00

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    authors: Lindquist MA,Geuter S,Wager TD,Caffo BS

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  • The influence of visual training on predicting complex action sequences.

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    pub_type: 杂志文章


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  • Gray matter correlates of dopaminergic degeneration in Parkinson's disease: A hybrid PET/MR study using (18) F-FP-CIT.

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Hagler DJ Jr

    更新日期:2014-05-01 00:00:00

  • Early red nucleus atrophy in relapse-onset multiple sclerosis.

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    pub_type: 杂志文章


    authors: Margoni M,Poggiali D,Zywicki S,Rubin M,Lazzarotto A,Franciotta S,Anglani MG,Causin F,Rinaldi F,Perini P,Filippi M,Gallo P

    更新日期:2021-01-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章,评审


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    更新日期:1999-01-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


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    更新日期:2006-08-01 00:00:00

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    authors: Spielberg JM,Sadeh N,Leritz EC,McGlinchey RE,Milberg WP,Hayes JP,Salat DH

    更新日期:2017-06-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Li L,Li KK,Li J

    更新日期:2019-06-01 00:00:00

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    pub_type: 杂志文章


    authors: Derrfuss J,Brass M,von Cramon DY,Lohmann G,Amunts K

    更新日期:2009-01-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Jessen F,Manka C,Scheef L,Granath DO,Schild HH,Heun R

    更新日期:2002-12-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Jeurissen B,Leemans A,Jones DK,Tournier JD,Sijbers J

    更新日期:2011-03-01 00:00:00

  • A network of amygdala connections predict individual differences in trait anxiety.

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Greening SG,Mitchell DG

    更新日期:2015-12-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Wang L,Dai Z,Peng H,Tan L,Ding Y,He Z,Zhang Y,Xia M,Li Z,Li W,Cai Y,Lu S,Liao M,Zhang L,Wu W,He Y,Li L

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    pub_type: 杂志文章,评审


    authors: Ruge H,Jamadar S,Zimmermann U,Karayanidis F

    更新日期:2013-01-01 00:00:00

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    pub_type: 临床试验,杂志文章


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    更新日期:1999-01-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Cooke A,Zurif EB,DeVita C,Alsop D,Koenig P,Detre J,Gee J,Pinãngo M,Balogh J,Grossman M

    更新日期:2002-02-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Bilalić M,Turella L,Campitelli G,Erb M,Grodd W

    更新日期:2012-11-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Schwabe L,Lenggenhager B,Blanke O

    更新日期:2009-06-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Tholen MG,Trautwein FM,Böckler A,Singer T,Kanske P

    更新日期:2020-07-01 00:00:00

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    journal_title:Human brain mapping

    pub_type: 杂志文章


    authors: Verly M,Verhoeven J,Zink I,Mantini D,Van Oudenhove L,Lagae L,Sunaert S,Rommel N

    更新日期:2014-08-01 00:00:00