A technical review of canonical correlation analysis for neuroscience applications.

Abstract:

:Collecting comprehensive data sets of the same subject has become a standard in neuroscience research and uncovering multivariate relationships among collected data sets have gained significant attentions in recent years. Canonical correlation analysis (CCA) is one of the powerful multivariate tools to jointly investigate relationships among multiple data sets, which can uncover disease or environmental effects in various modalities simultaneously and characterize changes during development, aging, and disease progressions comprehensively. In the past 10 years, despite an increasing number of studies have utilized CCA in multivariate analysis, simple conventional CCA dominates these applications. Multiple CCA-variant techniques have been proposed to improve the model performance; however, the complicated multivariate formulations and not well-known capabilities have delayed their wide applications. Therefore, in this study, a comprehensive review of CCA and its variant techniques is provided. Detailed technical formulation with analytical and numerical solutions, current applications in neuroscience research, and advantages and limitations of each CCA-related technique are discussed. Finally, a general guideline in how to select the most appropriate CCA-related technique based on the properties of available data sets and particularly targeted neuroscience questions is provided.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Zhuang X,Yang Z,Cordes D

doi

10.1002/hbm.25090

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

3807-3833

issue

13

eissn

1065-9471

issn

1097-0193

journal_volume

41

pub_type

杂志文章,评审
  • Common and unique connectivity at the interface of motor, neuropsychiatric, and cognitive symptoms in Parkinson's disease: A commonality analysis.

    abstract::Parkinson's disease (PD) is characterized by overlapping motor, neuropsychiatric, and cognitive symptoms. Worse performance in one domain is associated with worse performance in the other domains. Commonality analysis (CA) is a method of variance partitioning in multiple regression, used to separate the specific and c...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25084

    authors: Lang S,Ismail Z,Kibreab M,Kathol I,Sarna J,Monchi O

    更新日期:2020-09-01 00:00:00

  • Wavelet-based regularity analysis reveals recurrent spatiotemporal behavior in resting-state fMRI.

    abstract::One of the major findings from multimodal neuroimaging studies in the past decade is that the human brain is anatomically and functionally organized into large-scale networks. In resting state fMRI (rs-fMRI), spatial patterns emerge when temporal correlations between various brain regions are tallied, evidencing netwo...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22865

    authors: Smith RX,Jann K,Ances B,Wang DJ

    更新日期:2015-09-01 00:00:00

  • Preserved executive function in high-performing elderly is driven by large-scale recruitment of prefrontal cortical mechanisms.

    abstract::High-density electrical mapping of event-related potentials was used to investigate the neural processes that permit some elderly subjects to preserve high levels of executive functioning. Two possibilities pertain: (1) high-performance in elderly subjects is underpinned by similar processing mechanisms to those seen ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20839

    authors: De Sanctis P,Gomez-Ramirez M,Sehatpour P,Wylie GR,Foxe JJ

    更新日期:2009-12-01 00:00:00

  • Relationship between structural and functional connectivity change across the adult lifespan: A longitudinal investigation.

    abstract::Extensive efforts are devoted to understand the functional (FC) and structural connections (SC) of the brain. FC is usually measured by functional magnetic resonance imaging (fMRI), and conceptualized as degree of synchronicity in brain activity between different regions. SC is typically indexed by measures of white m...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23403

    authors: Fjell AM,Sneve MH,Grydeland H,Storsve AB,Amlien IK,Yendiki A,Walhovd KB

    更新日期:2017-01-01 00:00:00

  • Abnormal neural response to phonological working memory demands in persistent developmental stuttering.

    abstract::Persistent developmental stuttering is a neurological disorder that commonly manifests as a motor problem. Cognitive theories, however, hold that poorly developed cognitive skills are the origins of stuttering. Working memory (WM), a multicomponent cognitive system that mediates information maintenance and manipulatio...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24366

    authors: Yang Y,Jia F,Fox PT,Siok WT,Tan LH

    更新日期:2019-01-01 00:00:00

  • Determining the hemispheric dominance of spatial attention: a comparison between fTCD and fMRI.

    abstract::Human brain mapping allows the systematic assessment of interindividual differences in functional brain anatomy. Functional transcranial Doppler sonography (fTCD) is an imaging tool that allows for fast and mobile assessment of hemispheric lateralization of task-related brain activation. It is ideal to screen large co...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20055

    authors: Jansen A,Flöel A,Deppe M,van Randenborgh J,Dräger B,Kanowski M,Knecht S

    更新日期:2004-11-01 00:00:00

  • Learned control of inter-hemispheric connectivity: Effects on bimanual motor performance.

    abstract::Bimanual movements involve the interactions between both primary motor cortices. These interactions are assumed to involve phase-locked oscillatory brain activity referred to as inter-hemispheric functional coupling. So far, inter-hemispheric functional coupling has been investigated as a function of motor performance...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23663

    authors: Kajal DS,Braun C,Mellinger J,Sacchet MD,Ruiz S,Fetz E,Birbaumer N,Sitaram R

    更新日期:2017-09-01 00:00:00

  • Individual variability in the shape and amplitude of the BOLD-HRF correlates with endogenous GABAergic inhibition.

    abstract::It has previously been demonstrated that there is a negative correlation between the amplitude of the BOLD response and resting γ amino-butyric acid (GABA) concentration in visual cortex. The work here is the first to empirically characterize individual variability in the haemodynamic response functions (HRFs) in resp...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21223

    authors: Muthukumaraswamy SD,Evans CJ,Edden RA,Wise RG,Singh KD

    更新日期:2012-02-01 00:00:00

  • Interactions between visual and motor areas during the recognition of plausible actions as revealed by magnetoencephalography.

    abstract::Several studies have shown activation of the mirror neuron system (MNS), comprising the temporal, posterior parietal, and sensorimotor areas when observing plausible actions, but far less is known on how these cortical areas interact during the recognition of a plausible action. Here, we recorded neural activity with ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22207

    authors: Pavlidou A,Schnitzler A,Lange J

    更新日期:2014-02-01 00:00:00

  • Primary visual response (M100) delays in adolescents with FASD as measured with MEG.

    abstract::Fetal alcohol spectrum disorders (FASD) are debilitating, with effects of prenatal alcohol exposure persisting into adolescence and adulthood. Complete characterization of FASD is crucial for the development of diagnostic tools and intervention techniques to decrease the high cost to individual families and society of...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22110

    authors: Coffman BA,Kodituwakku P,Kodituwakku EL,Romero L,Sharadamma NM,Stone D,Stephen JM

    更新日期:2013-11-01 00:00:00

  • Brain structural correlates of irritability: Findings in a large healthy cohort.

    abstract::Irritability and nonviolent aggression are common behavioral features across the population, yet there is limited neurobiological research into subclinical phenotypes representing the lower edge of a symptom continuum ranging from slight irritability to criminal violence. We studied brain structural correlates of irri...

    journal_title:Human brain mapping

    pub_type: 杂志文章,多中心研究

    doi:10.1002/hbm.23824

    authors: Besteher B,Squarcina L,Spalthoff R,Bellani M,Gaser C,Brambilla P,Nenadić I

    更新日期:2017-12-01 00:00:00

  • Effects of different viewing perspectives on somatosensory activations during observation of touch.

    abstract::Previous studies showed that neurons in the monkey premotor cortex became active when performing a particular action and also when observing the same action performed by others. These findings suggest a mirror system for action observation. Recently, bimodal neurons, sensitive both to visual and tactile stimulation, w...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20701

    authors: Schaefer M,Xu B,Flor H,Cohen LG

    更新日期:2009-09-01 00:00:00

  • Visual processing as a potential endophenotype in youths with attention-deficit/hyperactivity disorder: A sibling study design using the counting Stroop functional MRI.

    abstract::Deficits in inhibitory control and visual processing are common in youths with attention-deficit/hyperactivity disorder (ADHD), but little is known about endophenotypes for unaffected siblings of youths with ADHD. This study aimed to investigate the potential endophenotypes of brain activation and performance in inhib...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24214

    authors: Fan LY,Shang CY,Tseng WI,Gau SS,Chou TL

    更新日期:2018-10-01 00:00:00

  • Mapping structural differences of the corpus callosum in individuals with 18q deletions using targetless regional spatial normalization.

    abstract::Individuals with a constitutional chromosome abnormality consisting of a deletion of a portion of the long arm of chromosome 18 (18q-) have a high incidence ( approximately 95%) of dysmyelination. Neuroradiologic findings in affected children report a smaller corpus callosum, but this finding has not been quantified. ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20090

    authors: Kochunov P,Lancaster J,Hardies J,Thompson PM,Woods RP,Cody JD,Hale DE,Laird A,Fox PT

    更新日期:2005-04-01 00:00:00

  • Brain and soccer: Functional patterns of brain activity during the generation of creative moves in real soccer decision-making situations.

    abstract::This fMRI study investigated brain activity while soccer players were imagining creative moves in real soccer decision-making situations. After presenting brief video clips of a soccer scene, participants had to imagine themselves as the acting player and think either of a creative or obvious move that might lead to a...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24408

    authors: Fink A,Bay JU,Koschutnig K,Prettenthaler K,Rominger C,Benedek M,Papousek I,Weiss EM,Seidel A,Memmert D

    更新日期:2019-02-15 00:00:00

  • Altered interregional molecular associations of the serotonin transporter in attention deficit/hyperactivity disorder assessed with PET.

    abstract::Altered serotonergic neurotransmission has been found to cause impulsive and aggressive behavior, as well as increased motor activity, all exemplifying key symptoms of ADHD. The main objectives of this positron emission tomography (PET) study were to investigate the serotonin transporter binding potential (SERT BPND )...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23418

    authors: Vanicek T,Kutzelnigg A,Philippe C,Sigurdardottir HL,James GM,Hahn A,Kranz GS,Höflich A,Kautzky A,Traub-Weidinger T,Hacker M,Wadsak W,Mitterhauser M,Kasper S,Lanzenberger R

    更新日期:2017-02-01 00:00:00

  • Thalamocortical sensorimotor circuit in multiple sclerosis: an integrated structural and electrophysiological assessment.

    abstract::Demyelination and axonal damage are pathologic hallmarks of multiple sclerosis (MS), leading to loss of neuronal synchronization, functional disconnection amongst brain relays, and clinical sequelae. To investigate these properties, the primary component of the sensorimotor network was analyzed in mildly disabled Rela...

    journal_title:Human brain mapping

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/hbm.20961

    authors: Dell'Acqua ML,Landi D,Zito G,Zappasodi F,Lupoi D,Rossini PM,Filippi MM,Tecchio F

    更新日期:2010-10-01 00:00:00

  • Scanning patients with tasks they can perform.

    abstract::We present an overview of the types of imaging experiments that can be performed on psychologically impaired patients. The critical observation from such studies is a differential pattern of activation in the patients and normals. Underactivity is interpretable only when the patients make normal responses. In this con...

    journal_title:Human brain mapping

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1097-0193(1999)8:2/3<102::aid-hbm6>3

    authors: Price CJ,Friston KJ

    更新日期:1999-01-01 00:00:00

  • Persistent default-mode network connectivity during light sedation.

    abstract::The default-mode network (DMN) is a set of specific brain regions whose activity, predominant in the resting-state, is attenuated during cognitively demanding, externally-cued tasks. The cognitive correlates of this network have proven difficult to interrogate, but one hypothesis is that regions in the network process...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20537

    authors: Greicius MD,Kiviniemi V,Tervonen O,Vainionpää V,Alahuhta S,Reiss AL,Menon V

    更新日期:2008-07-01 00:00:00

  • Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging.

    abstract::The concept of brain maintenance refers to the preservation of brain integrity in older age, while cognitive reserve refers to the capacity to maintain cognition in the presence of neurodegeneration or aging-related brain changes. While both mechanisms are thought to contribute to individual differences in cognitive f...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25316

    authors: Anatürk M,Kaufmann T,Cole JH,Suri S,Griffanti L,Zsoldos E,Filippini N,Singh-Manoux A,Kivimäki M,Westlye LT,Ebmeier KP,de Lange AG

    更新日期:2020-12-14 00:00:00

  • Neural association between non-verbal number sense and arithmetic fluency.

    abstract::Non-verbal number sense has been shown to significantly correlate with arithmetic fluency. Accumulated behavioral evidence indicates that the cognitive mechanism relies on visual perception. However, few studies have investigated the neural mechanism underlying this association. Following the visual perception account...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25179

    authors: Li M,Cheng D,Lu Y,Zhou X

    更新日期:2020-12-15 00:00:00

  • Encoding touch and the orbitofrontal cortex.

    abstract::Lesion studies on nonhuman primates utilizing recognition memory tests have shown that the orbitofrontal cortex is critical for the encoding of novel information, and anatomical studies have shown that the orbitofrontal cortex forms part of a mnemonic circuit that connects limbic medial temporal areas with higher-orde...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20532

    authors: Frey S,Zlatkina V,Petrides M

    更新日期:2009-02-01 00:00:00

  • Predictive modeling of EEG time series for evaluating surgery targets in epilepsy patients.

    abstract::During the last 20 years, predictive modeling in epilepsy research has largely been concerned with the prediction of seizure events, whereas the inference of effective brain targets for resective surgery has received surprisingly little attention. In this exploratory pilot study, we describe a distributional clusterin...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23537

    authors: Steimer A,Müller M,Schindler K

    更新日期:2017-05-01 00:00:00

  • Altered neural signatures of interoception in multiple sclerosis.

    abstract::Multiple sclerosis (MS) patients present several alterations related to sensing of bodily signals. However, no specific neurocognitive impairment has yet been proposed as a core deficit underlying such symptoms. We aimed to determine whether MS patients present changes in interoception-that is, the monitoring of auton...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24319

    authors: Salamone PC,Esteves S,Sinay VJ,García-Cordero I,Abrevaya S,Couto B,Adolfi F,Martorell M,Petroni A,Yoris A,Torquati K,Alifano F,Legaz A,Cassará FP,Bruno D,Kemp AH,Herrera E,García AM,Ibáñez A,Sedeño L

    更新日期:2018-12-01 00:00:00

  • Exploring the unity and diversity of the neural substrates of executive functioning.

    abstract::Previous studies exploring the neural substrates of executive functioning used task-specific analyses, which might not be the most appropriate approach due to the difficulty of precisely isolating executive functions. Consequently, the aim of this study was to use positron emission tomography (PET) to reexamine by con...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20118

    authors: Collette F,Van der Linden M,Laureys S,Delfiore G,Degueldre C,Luxen A,Salmon E

    更新日期:2005-08-01 00:00:00

  • Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning.

    abstract::The goal of this study was to document current clinical practice and report patient outcomes in presurgical language functional MRI (fMRI) for epilepsy surgery. Epilepsy surgical programs worldwide were surveyed as to the utility, implementation, and efficacy of language fMRI in the clinic; 82 programs responded. Resp...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24039

    authors: Benjamin CFA,Li AX,Blumenfeld H,Constable RT,Alkawadri R,Bickel S,Helmstaedter C,Meletti S,Bronen R,Warfield SK,Peters JM,Reutens D,Połczyńska M,Spencer DD,Hirsch LJ

    更新日期:2018-07-01 00:00:00

  • Age-related changes in the cerebral substrates of cognitive procedural learning.

    abstract::Cognitive procedural learning occurs in three qualitatively different phases (cognitive, associative, and autonomous). At the beginning of this process, numerous cognitive functions are involved, subtended by distinct brain structures such as the prefrontal and parietal cortex and the cerebellum. As the learning progr...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20605

    authors: Hubert V,Beaunieux H,Chételat G,Platel H,Landeau B,Viader F,Desgranges B,Eustache F

    更新日期:2009-04-01 00:00:00

  • A novel method for integrating MEG and BOLD fMRI signals with the linear convolution model in human primary somatosensory cortex.

    abstract::Characterizing the neurovascular coupling between hemodynamic signals and their neural origins is crucial to functional neuroimaging research, even more so as new methods become available for integrating results from different functional neuroimaging modalities. We present a novel method to relate magnetoencephalograp...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20361

    authors: Nangini C,Tam F,Graham SJ

    更新日期:2008-01-01 00:00:00

  • Social cognition and the brain: a meta-analysis.

    abstract::This meta-analysis explores the location and function of brain areas involved in social cognition, or the capacity to understand people's behavioral intentions, social beliefs, and personality traits. On the basis of over 200 fMRI studies, it tests alternative theoretical proposals that attempt to explain how several ...

    journal_title:Human brain mapping

    pub_type: 杂志文章,meta分析

    doi:10.1002/hbm.20547

    authors: Van Overwalle F

    更新日期:2009-03-01 00:00:00

  • Resting-state functional MRI: functional connectivity analysis of the visual cortex in primary open-angle glaucoma patients.

    abstract:PURPOSE:To analyze functional connectivity (FC) of the visual cortex using resting-state functional MRI in human primary open-angle glaucoma (POAG) patients. MATERIALS AND METHODS:Twenty-two patients with known POAG and 22 age-matched controls were included in this IRB-approved study. Subjects were evaluated by 3 T MR...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22079

    authors: Dai H,Morelli JN,Ai F,Yin D,Hu C,Xu D,Li Y

    更新日期:2013-10-01 00:00:00