Transfer and Integration of Breast Milk Stem Cells to the Brain of Suckling Pups.

abstract：:Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that mediates phosphoinositide-3-kinase (PI3K)/AKT signalling. This pathway is involved in a plethora of cellular functions including protein and lipid synthesis, cell migration, cell proliferation and apoptosis. In this study, we proposed to ...

journal_title：Scientific reports

authors： Malik N,Dunn KM,Cassels J,Hay J,Estell C,Sansom OJ,Michie AM

更新日期：2019-11-15 00:00:00

abstract：:The ability to reprogram adult somatic cells into induced pluripotent stem cells (iPSCs) and the subsequent development of protocols for their differentiation into disease-relevant cell types have enabled in-depth molecular analyses of multiple disease states as hitherto impossible. Neurons differentiated from patient...

journal_title：Scientific reports

authors： Heman-Ackah SM,Bassett AR,Wood MJ

更新日期：2016-06-24 00:00:00

abstract：:Voltage-gated sodium channels (VGSCs) play a vital role in controlling neuronal excitability. Nav1.6 is the most abundantly expressed VGSCs subtype in the adult central nervous system and has been found to contribute to facilitate the hyperexcitability of neurons after electrical induction of status epilepticus (SE). ...

journal_title：Scientific reports

authors： Zhu H,Zhao Y,Wu H,Jiang N,Wang Z,Lin W,Jin J,Ji Y

更新日期：2016-12-01 00:00:00

abstract：:Nowadays efficient down conversion for white light emission is mainly based on rare-earth doped phosphors or cadmium-containing quantum dots. Although they exhibit high luminescence efficiency, the rare-earth mining and cadmium pollution have so far led to extremely high environmental cost, which conflicts the origina...

journal_title：Scientific reports

authors： Shen PC,Lin MS,Lin CF

更新日期：2014-06-16 00:00:00

abstract：:The non-enzymatic browning, namely Maillard reaction is commonly invoked to account for abiotic chemical transformations of organic matter. Here we report a new reaction pathway via the Maillard reaction to systematically synthesize a series of nitrogen-doped carbon dots (C-dots) with superhigh quantum yield (QY) and ...

journal_title：Scientific reports

authors： Wei W,Xu C,Wu L,Wang J,Ren J,Qu X

更新日期：2014-01-06 00:00:00

abstract：:Lipid droplet (LD)-associated hydrolase (LDAH) is a newly identified LD protein abundantly expressed in tissues that predominantly store triacylglycerol (TAG). However, how LDAH regulates TAG metabolism remains unknown. We found that upon oleic acid loading LDAH translocalizes from the ER to newly formed LDs, and indu...

journal_title：Scientific reports

authors： Goo YH,Son SH,Paul A

更新日期：2017-06-02 00:00:00

abstract：:Copper ions play a vital role in a variety of fundamental physiological processes not only in human beings and plants, but also for extensive insects and microorganisms. In this paper, a novel water-soluble ruthenium(II) complex as a turn-on copper(II) ions luminescent sensor based on o-(phenylazo)aniline was designed...

journal_title：Scientific reports

authors： Zhang Y,Liu Z,Yang K,Zhang Y,Xu Y,Li H,Wang C,Lu A,Sun S

更新日期：2015-02-02 00:00:00

abstract：:Emergence and time evolution of micro-structured new-phase domains play a crucial role in determining the macroscopic physical and mechanical behaviors of iron under shock compression. Here, we investigate, through molecular dynamics simulations and theoretical modelings, shock-induced phase transition process of iron...

journal_title：Scientific reports

authors： Pang WW,Zhang P,Zhang GC,Xu AG,Zhao XG

更新日期：2014-01-10 00:00:00

abstract：:Periventricular nodular heterotopia (PNH) is a neural migration disorder which often presents clinically with seizures. However, the underlying functional neural basis of PNH is still unclear. We aimed to explore the underlying pathological mechanism of PNH by combining both whole brain functional connectivity (FC) an...

journal_title：Scientific reports

authors： Liu W,Hu X,An D,Zhou D,Gong Q

更新日期：2019-12-05 00:00:00

abstract：:Calcium ion is an intracellular messenger that plays a central role in signal transduction pathways. Calcineurin B-like proteins (CBLs) and CBL-interacting protein kinases (CIPKs) signal network have shown different functions in the Ca(2+) signaling process. In this work, we identified the entire soybean (Glycine max)...

journal_title：Scientific reports

authors： Zhu K,Chen F,Liu J,Chen X,Hewezi T,Cheng ZM

更新日期：2016-06-17 00:00:00

abstract：:The tick receptor for outer surface protein A (TROSPA) is the only identified factor involved in tick gut colonization by various Borrelia species. TROSPA is localized in the gut epithelium and can recognize and bind the outer surface bacterial protein OspA via an unknown mechanism. Based on earlier reports and our la...

journal_title：Scientific reports

authors： Urbanowicz A,Lewandowski D,Szpotkowski K,Figlerowicz M

更新日期：2016-04-26 00:00:00

abstract：:Experiments on the Ultimatum Game (UG) repeatedly show that people's behaviour is far from rational. In UG experiments, a subject proposes how to divide a pot and the other can accept or reject the proposal, in which case both lose everything. While rational people would offer and accept the minimum possible amount, i...

journal_title：Scientific reports

authors： Han X,Cao S,Bao JZ,Wang WX,Zhang B,Gao ZY,Sánchez A

更新日期：2018-01-19 00:00:00

abstract：:Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities. Mutations in hANG have been found in patients with Amyotrophic lateral sclerosis (ALS). The zebrafish (Danio rerio) rnasel-1, 2 and 3 are orthologues of hANG and of these only Rnasel-1 and Rnasel-...

journal_title：Scientific reports

authors： Ferguson R,Holloway DE,Chandrasekhar A,Acharya KR,Subramanian V

更新日期：2019-02-01 00:00:00

abstract：:The influence of dose rate on radiation cataractogenesis has yet to be extensively studied. One recent epidemiological investigation suggested that protracted radiation exposure increases radiation-induced cataract risk: cumulative doses of radiation mostly <100 mGy received by US radiologic technologists over 5 years...

journal_title：Scientific reports

authors： Barnard SGR,McCarron R,Moquet J,Quinlan R,Ainsbury E

更新日期：2019-07-18 00:00:00

abstract：:This study aims to evaluate the diagnostic accuracy of digital breast tomosynthesis-guided vacuum assisted breast biopsy (DBT-VABB) of screening detected suspicious mammographic abnormalities comprising of calcifications, asymmetric densities, architectural distortions and spiculated masses. In this institutionally ap...

journal_title：Scientific reports

authors： Bohan S,Ramli Hamid MT,Chan WY,Vijayananthan A,Ramli N,Kaur S,Rahmat K

更新日期：2021-01-08 00:00:00

abstract：:The Holocene drying trend in the northern Altai Mountains and the wetting trend in the southern Altai Mountains inferred from the paleoclimatic studies indicated it is needed to understand the modern climatic characters in this region. However, a detailed analysis of modern climate variations in the northern and south...

journal_title：Scientific reports

authors： Zhang D,Yang Y,Lan B

更新日期：2018-02-19 00:00:00

abstract：:This study measured the effects of vitamin D (VD) supplementation on the underlying molecular pathways involved in renal and testicular damage induced by lead (Pb) toxicity. Thirty two adult male Wistar rats were divided equally into four groups that were treated individually or simultaneously, except the negative con...

journal_title：Scientific reports

authors： BaSalamah MA,Abdelghany AH,El-Boshy M,Ahmad J,Idris S,Refaat B

更新日期：2018-03-19 00:00:00

abstract：:GABAergic and glutamatergic dysfunction in the dorsolateral prefrontal cortex (DLPFC) are thought to be the core pathophysiological mechanisms of schizophrenia. Recently, we have established a method to index these functions from the DLPFC using the paired transcranial magnetic stimulation (TMS) paradigms of short int...

journal_title：Scientific reports

authors： Noda Y,Barr MS,Zomorrodi R,Cash RFH,Farzan F,Rajji TK,Chen R,Daskalakis ZJ,Blumberger DM

更新日期：2017-12-06 00:00:00

abstract：:The receptor guanylate cyclases (rGCs) in animals serve as sensitive chemoreceptors to detect both chemical and environmental cues. In reproduction, rGCs were shown to be expressed on sperm and serve as receptors for egg-derived sperm-activating and sperm-attracting factors in some echinoderms and mammals. However, sp...

journal_title：Scientific reports

authors： Zhang Y,Chiu YL,Chen CJ,Ho YY,Shinzato C,Shikina S,Chang CF

更新日期：2019-10-10 00:00:00

abstract：:Crustaceans form the second largest subphylum on Earth, which includes Litopeneaus vannamei (Pacific whiteleg shrimp), one of the most cultured shrimp worldwide. Despite efforts to study the shrimp microbiota, little is known about it from shrimp obtained from the open sea and the role that aquaculture plays in microb...

journal_title：Scientific reports

authors： Cornejo-Granados F,Lopez-Zavala AA,Gallardo-Becerra L,Mendoza-Vargas A,Sánchez F,Vichido R,Brieba LG,Viana MT,Sotelo-Mundo RR,Ochoa-Leyva A

更新日期：2017-09-18 00:00:00

abstract：:A dual mode rare-earth based vanadate material (YVO4: Ho3+/Yb3+), prepared through ethylene glycol assisted hydrothermal method, demonstrating both downconversion and upconversion, along with systematic investigation of the luminescence spectroscopy within 12-300 K is presented herein. The energy transfer processes ha...

journal_title：Scientific reports

authors： Kumar Mahata M,Koppe T,Kumar K,Hofsäss H,Vetter U

更新日期：2016-11-02 00:00:00

abstract：:Differential scanning fluorimetry is a popular method to estimate the stability of a protein in distinct buffer conditions by determining its 'melting point'. The method requires a temperature controlled fluorescence spectrometer or a RT-PCR machine. Here, we introduce a low-budget version of a microcontroller based h...

journal_title：Scientific reports

authors： Hoeser J,Gnandt E,Friedrich T

更新日期：2018-01-23 00:00:00

abstract：:Stress and recovery from stress significantly affect interactions between the central nervous system, endocrine pathways, and the immune system. However, the influence of acute stress on circulating immune-endocrine mediators in humans is not well known. Using a double-blind, randomized study design, we administered a...

journal_title：Scientific reports

authors： Koelsch S,Boehlig A,Hohenadel M,Nitsche I,Bauer K,Sack U

更新日期：2016-03-29 00:00:00

abstract：:With the advent of nanotechnology, a variety of nanoarchitectures with varied physicochemical properties have been designed. Owing to the unique characteristics, DNAs have been used as a functional building block for novel nanoarchitecture. In particular, a self-assembly of long DNA molecules via a piece DNA staple ha...

journal_title：Scientific reports

authors： Song IH,Shin SW,Park KS,Lansac Y,Jang YH,Um SH

更新日期：2015-12-04 00:00:00

abstract：:The 30-day readmission rate after hospitalization for a sickle cell crisis (SCC) is extremely high. Accurate information on readmission diagnoses, total readmission costs and factors associated with readmission is required to effectively plan resource allocation and to plan interventions to reduce readmission rates. T...

journal_title：Scientific reports

authors： Kumar V,Chaudhary N,Achebe MM

更新日期：2020-02-07 00:00:00

abstract：:Pulsatillae radix is a conventional traditional Chinese medicine (TCM) with common name Baitouweng, and has notable effects on inflammation and dysentery. Pulsatilla chinensis (Bge.) Regel is the only source plant of Baitouweng recorded in Chinese Pharmacopoeia, but its adulteration often occurs in the market that pos...

journal_title：Scientific reports

authors： Shi Y,Zhao M,Yao H,Yang P,Xin T,Li B,Sun W,Chen S

更新日期：2017-01-06 00:00:00

abstract：:Using the universal structure predictor algorithm, we proposed that two-dimensional MnB structures with p4mmm (α-MnB) and pmma (β-MnB) symmetries could be synthesized. This finding was verified by calculating the dynamical stability, molecular dynamics, and mechanical properties. The α-MnB had an in-plane stiffness Y ...

journal_title：Scientific reports

authors： Farooq MU,Hashmi A,Khan I,Hong J

更新日期：2017-12-06 00:00:00

abstract：:Ultrasound imaging is affected by coherent noise or speckle, which reduces contrast and overall image quality and degrades the diagnostic precision of the collected images. Elevational angular compounding (EAC) is an attractive means of addressing this limitation, since it reduces speckle noise while operating in real...

journal_title：Scientific reports

authors： Afshari P,Zakian C,Ntziachristos V

更新日期：2020-10-23 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a useful noninvasive technique of cortical brain stimulation for the treatment of neurological disorders. Clinical research has demonstrated tDCS with anodal stimulation of primary motor cortex (M1) in Parkinson's disease (PD) patients significantly improved their moto...

journal_title：Scientific reports

authors： Li H,Lei X,Yan T,Li H,Huang B,Li L,Xu L,Liu L,Chen N,Lü L,Ma Y,Xu L,Li J,Wang Z,Zhang B,Hu X

更新日期：2015-07-29 00:00:00

abstract：:Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulated in various human carcinoma...

journal_title：Scientific reports

authors： Mishel S,Shneyer B,Korsensky L,Goldshmidt-Tran O,Haber T,Machluf M,Ron D

更新日期：2017-11-08 00:00:00