Abstract:
:Understanding ice sheet behaviour in the geological past is essential for evaluating the role of the cryosphere in the climate system and for projecting rates and magnitudes of sea level rise in future warming scenarios1-4. Although both geological data5-7 and ice sheet models3,8 indicate that marine-based sectors of the East Antarctic Ice Sheet were unstable during Pliocene warm intervals, the ice sheet dynamics during late Pleistocene interglacial intervals are highly uncertain3,9,10. Here we provide evidence from marine sedimentological and geochemical records for ice margin retreat or thinning in the vicinity of the Wilkes Subglacial Basin of East Antarctica during warm late Pleistocene interglacial intervals. The most extreme changes in sediment provenance, recording changes in the locus of glacial erosion, occurred during marine isotope stages 5, 9, and 11, when Antarctic air temperatures11 were at least two degrees Celsius warmer than pre-industrial temperatures for 2,500 years or more. Hence, our study indicates a close link between extended Antarctic warmth and ice loss from the Wilkes Subglacial Basin, providing ice-proximal data to support a contribution to sea level from a reduced East Antarctic Ice Sheet during warm interglacial intervals. While the behaviour of other regions of the East Antarctic Ice Sheet remains to be assessed, it appears that modest future warming may be sufficient to cause ice loss from the Wilkes Subglacial Basin.
journal_name
Naturejournal_title
Natureauthors
Wilson DJ,Bertram RA,Needham EF,van de Flierdt T,Welsh KJ,McKay RM,Mazumder A,Riesselman CR,Jimenez-Espejo FJ,Escutia Cdoi
10.1038/s41586-018-0501-8subject
Has Abstractpub_date
2018-09-01 00:00:00pages
383-386issue
7723eissn
0028-0836issn
1476-4687pii
10.1038/s41586-018-0501-8journal_volume
561pub_type
历史文章,杂志文章相关文献
NATURE文献大全abstract::Ordinarily, photons do not interact with one another. However, atoms can be used to mediate photonic interactions1,2, raising the prospect of forming synthetic materials3 and quantum information systems4-7 from photons. One promising approach combines highly excited Rydberg atoms8-12 with the enhanced light-matter cou...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/s41586-019-1354-5
更新日期:2019-07-01 00:00:00
abstract::In the course of synaptic transmission in the brain and periphery, acetylcholine receptors (AChRs) rapidly transduce a chemical signal into an electrical impulse. The speed of transduction is facilitated by rapid ACh association and dissociation, suggesting a binding site relatively non-selective for small cations. Se...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature07923
更新日期:2009-05-21 00:00:00
abstract::Cellular ras genes encode a family of membrane-associated proteins (p21ras) that bind guanine nucleotide and possess a low intrinsic GTPase activity. The p21ras proteins are ubiquitously expressed in mammalian cells and are thought to be involved in a growth-promoting signal transduction pathway; their mode of action,...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/347396a0
更新日期:1990-09-27 00:00:00
abstract:: ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/d41586-019-00676-y
更新日期:2019-02-01 00:00:00
abstract::Dopamine (DA) has largely been ignored in considering possible mechanisms underlying the therapeutic effects of tricyclic anti-depressants (TCA). Most previous work done has focused on the ability of some TCAs to block the in vitro re-uptake of DA--an effect which unfortunately requires very high doses. Recently, howe...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/287451a0
更新日期:1980-10-02 00:00:00
abstract::Binocular coordination of eye movements is essential for stereopsis (depth perception) and to prevent double vision. More than a century ago, Hering and Helmholtz debated the neural basis of binocular coordination. Helmholtz believed that each eye is controlled independently and that binocular coordination is learned....
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/31489
更新日期:1998-06-18 00:00:00
abstract::More than twenty types of retinal ganglion cells conduct visual information from the eye to the rest of the brain. Each retinal ganglion cell type tessellates the retina in a regular mosaic, so that every point in visual space is processed for visual primitives such as contrast and motion. This information flows to tw...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature14103
更新日期:2015-03-12 00:00:00
abstract::A family of G-protein-coupled chemoattractant receptors is known to mediate the transport and activation of neutrophils and macrophages This family includes receptors for chemokines, such as interleukin-8, bacterial formylated peptides, platelet-activating factor, leukotriene B4, and the complement anaphylatoxins. The...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/383086a0
更新日期:1996-09-05 00:00:00
abstract::Acetylcholine (ACh) released on vagal stimulation reduces the heart rate by increasing K+ conductance of pacemaker cells in the sinoatrial (S-A) node. Fluctuation analysis of ACh-activated currents in pacemaker tissue showed this to be due to opening of a separate class of K+ channels gated by muscarinic ACh receptors...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/303250a0
更新日期:1983-05-19 00:00:00
abstract::How does the human visual system 'bind' different fragments in the visual scene to create enduring representations of objects? A visual illusion known as 'metacontrast' or backward masking provides compelling evidence that perception is not instantaneous and that it occurs sequentially in distinct stages. If a solid w...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/373066a0
更新日期:1995-01-05 00:00:00
abstract::Attempts to inhibit the recognition of soluble antigens by T lymphocytes using antibodies specific for the antigen in question have been uniformally unsuccessful, in contrast to the observed specific inhibition of antibody generation by B cells. One exception is the unique situation whereby anti-hapten antisera inhibi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/308547a0
更新日期:1984-04-05 00:00:00
abstract::Macroscopic mechanical objects and electromagnetic degrees of freedom can couple to each other through radiation pressure. Optomechanical systems in which this coupling is sufficiently strong are predicted to show quantum effects and are a topic of considerable interest. Devices in this regime would offer new types of...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06715
更新日期:2008-03-06 00:00:00
abstract::The conventional treatment of dental caries involves mechanical removal of the affected part and filling of the hole with a resin or metal alloy. But this method is not ideal for tiny early lesions because a disproportionate amount of healthy tooth must be removed to make the alloy or resin stick. Here we describe a d...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/433819a
更新日期:2005-02-24 00:00:00
abstract::Non-impulsive seismic radiation or 'tremor' has long been observed at volcanoes and more recently around subduction zones. Although the number of observations of non-volcanic tremor is steadily increasing, the causative mechanism remains unclear. Some have attributed non-volcanic tremor to the movement of fluids, whil...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06017
更新日期:2007-08-02 00:00:00
abstract::Many extensions of the Standard Model of particle physics explain the dominance of matter over antimatter in our Universe by neutrinos being their own antiparticles. This would imply the existence of neutrinoless double-β decay, which is an extremely rare lepton-number-violating radioactive decay process whose detecti...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature21717
更新日期:2017-04-05 00:00:00
abstract::Type II topoisomerases help regulate DNA topology during transcription, replication and recombination by catalysing DNA strand transfer through transient double-stranded breaks. All type II topoisomerases described so far are members of a single protein family. We have cloned and sequenced the genes encoding the A and...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/386414a0
更新日期:1997-03-27 00:00:00
abstract::The establishment and maintenance of epigenetic gene silencing is fundamental to cell determination and function. The essential epigenetic systems involved in heritable repression of gene activity are the Polycomb group (PcG) proteins and the DNA methylation systems. Here we show that the corresponding silencing pathw...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04431
更新日期:2006-02-16 00:00:00
abstract::When electrons are subject to a large external magnetic field, the conventional charge quantum Hall effect dictates that an electronic excitation gap is generated in the sample bulk, but metallic conduction is permitted at the boundary. Recent theoretical models suggest that certain bulk insulators with large spin-orb...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature06843
更新日期:2008-04-24 00:00:00
abstract::Transposable elements of DNA that are structurally defined and genetically discrete units seem to have an important role in the evolution of bacterial plasmids. Recombination occurring at the termini of such elements can result in the joining together of unrelated DNA segments that lack extensive nucleotide sequence h...
journal_title:Nature
pub_type: 杂志文章,评审
doi:10.1038/263731a0
更新日期:1976-10-28 00:00:00
abstract::The activation of T cells through interaction of their T-cell receptors with antigenic peptide bound to major histocompatibility complex (MHC) on the surface of antigen presenting cells (APCs) is a crucial step in adaptive immunity. Here we use three-dimensional fluorescence microscopy to visualize individual peptide-...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature01076
更新日期:2002-10-24 00:00:00
abstract::It is possible to infer aspects of an organism's lifestyle from its gene content. Can the reverse also be done? Here we consider this issue by modelling evolution of the reduced genomes of endosymbiotic bacteria. The diversity of gene content in these bacteria may reflect both variation in selective forces and conting...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature04568
更新日期:2006-03-30 00:00:00
abstract::Historical ecologists working in the Neotropics argue that the present natural environment is an historical product of human intentionality and ingenuity, a creation that is imposed, built, managed and maintained by the collective multigenerational knowledge and experience of Native Americans. In the past 12,000 years...
journal_title:Nature
pub_type: 历史文章,杂志文章
doi:10.1038/35041555
更新日期:2000-11-09 00:00:00
abstract::Breast cancer patients with the same stage of disease can have markedly different treatment responses and overall outcome. The strongest predictors for metastases (for example, lymph node status and histological grade) fail to classify accurately breast tumours according to their clinical behaviour. Chemotherapy or ho...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/415530a
更新日期:2002-01-31 00:00:00
abstract::The biosynthesis of many of the complement proteins by cells of the monocyte-macrophage series has been established. Studies on these cells using radiolabelled amino acids demonstrated synthesis of precursor proteins (pro-complement), and the native complement protein similar in size to that found in the plasma. Howev...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/298389a0
更新日期:1982-07-22 00:00:00
abstract::Ligand-gated ion channels, a major class of cell-surface proteins, have a pseudosymmetric structure with five highly homologous subunits arranged around a central ion pore. The correct assembly of each channel, whose subunit composition varies with cell type and stage of development, requires specific recognition betw...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/352064a0
更新日期:1991-07-04 00:00:00
abstract::Some beetles in the Namib Desert collect drinking water from fog-laden wind on their backs. We show here that these large droplets form by virtue of the insect's bumpy surface, which consists of alternating hydrophobic, wax-coated and hydrophilic, non-waxy regions. The design of this fog-collecting structure can be re...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/35102108
更新日期:2001-11-01 00:00:00
abstract::Excavations at the early Neolithic site of Jiahu in Henan Province, China have produced what may be the earliest complete, playable, tightly-dated multinote musical instruments. Jiahu was occupied from 7000 BC to 5700 BC, considerably antedating the well known Peiligang culture. Here we describe six exquisitely made c...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/43865
更新日期:1999-09-23 00:00:00
abstract::Glycine is an important inhibitory transmitter in the brainstem and spinal cord. In the trigeminal subnucleus caudalis (medullary dorsal horn) and in the spinal dorsal horn (the relaying centres for processing pain and sensory information), glycine inhibits the glutamate-evoked depolarization and depresses firing of n...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/348242a0
更新日期:1990-11-15 00:00:00
abstract::Ongoing efforts within synthetic and systems biology have been directed towards the building of artificial computational devices using engineered biological units as basic building blocks. Such efforts, inspired in the standard design of electronic circuits, are limited by the difficulties arising from wiring the basi...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/nature09679
更新日期:2011-01-13 00:00:00
abstract::The insulins of New World hystricomorph rodents exhibit many novel amino acid changes in primary structure when compared with other mammalian insulins. These changes give rise to unusual properties (low potency, failure to self-associate) not shared by other naturally-occurring insulins. We report here on the primary ...
journal_title:Nature
pub_type: 杂志文章
doi:10.1038/286822a0
更新日期:1980-08-21 00:00:00