G2Vec: Distributed gene representations for identification of cancer prognostic genes.

abstract：:In inflammatory bowel disease (IBD), compromised restitution of the epithelial barrier contributes to disease severity. Owing to the complexity in the pathogenesis of IBD, a variety of factors have been implicated in its progress. In this study, we report a functional interaction between macroautophagy and Corticotrop...

journal_title：Scientific reports

authors： Giannogonas P,Apostolou A,Manousopoulou A,Theocharis S,Macari SA,Psarras S,Garbis SD,Pothoulakis C,Karalis KP

更新日期：2016-03-18 00:00:00

abstract：:The bacterial second messenger cyclic di-3',5'-guanosine monophosphate (c-di-GMP) is a key regulator of bacterial motility and virulence. As high levels of c-di-GMP are associated with the biofilm lifestyle, c-di-GMP hydrolysing phosphodiesterases (PDEs) have been identified as key targets to aid development of novel ...

journal_title：Scientific reports

authors： Bellini D,Horrell S,Hutchin A,Phippen CW,Strange RW,Cai Y,Wagner A,Webb JS,Tews I,Walsh MA

更新日期：2017-02-10 00:00:00

abstract：:PROspective MOtion correction (PROMO) can prevent motion artefacts. The aim of this study was to determine whether brain structure measurements of motion-corrected images with PROMO were reliable and equivalent to conventional images without motion artefacts. The following T1-weighted images were obtained in healthy s...

journal_title：Scientific reports

authors： Watanabe K,Kakeda S,Igata N,Watanabe R,Narimatsu H,Nozaki A,Dan Rettmann,Abe O,Korogi Y

更新日期：2016-12-05 00:00:00

abstract：:There is increasing interest in the development of noninvasive diagnostic methods for early cancer detection, to improve the survival rate and quality of life of cancer patients. Identification of volatile metabolic compounds may provide an approach for noninvasive early diagnosis of malignant diseases. Here we analyz...

journal_title：Scientific reports

authors： He J,Sinues PM,Hollmén M,Li X,Detmar M,Zenobi R

更新日期：2014-06-06 00:00:00

abstract：:Investigation of quantum spin Hall states in 1T' phase of the monolayer transition metal dichalcogenides has recently attracted the attention for its potential in nanoelectronic applications. While most of the theoretical findings in this regard deal with infinitely periodic crystal structures, here we employ density ...

journal_title：Scientific reports

authors： Das B,Sen D,Mahapatra S

更新日期：2020-04-21 00:00:00

abstract：:Induction of cathelicidin-mediated antimicrobial pathway against intracellular M. tuberculosis by 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), the active form of vitamin D, has been documented in vitro. However, in in vivo studies related to inflammatory disorders, 1,25(OH)2D3 has been demonstrated to induce an anti-inflam...

journal_title：Scientific reports

authors： Bhatt K,Rafi W,Shah N,Christakos S,Salgame P

更新日期：2016-10-04 00:00:00

abstract：:The ability to wirelessly power electrical devices is becoming of greater urgency as a component of energy conservation and sustainability efforts. Due to health and safety concerns, most wireless power transfer (WPT) schemes utilize very low frequency, quasi-static, magnetic fields; power transfer occurs via magneto-...

journal_title：Scientific reports

authors： Lipworth G,Ensworth J,Seetharam K,Huang D,Lee JS,Schmalenberg P,Nomura T,Reynolds MS,Smith DR,Urzhumov Y

更新日期：2014-01-10 00:00:00

abstract：:Prostate cancer (PCa) is the most common solid neoplasm diagnosed in developed countries. Nerve-sparing radical prostatectomy (NS-RP) has been widely accepted as the best choice treatment for localised PCa. However, erectile dysfunction (ED) and urinary incontinence are commonly observed after NS-RP. Using meta-analys...

journal_title：Scientific reports

authors： Li J,Shi Q,Pu C,Tang Y,Bai Y,Yuan H,Li X,Dong Q,Wei Q,Yuan J,Han P

更新日期：2014-07-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Paul F,Otte J,Schmitt I,Grande FD

更新日期：2018-11-16 00:00:00

abstract：:Solution Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy coupled with enzymatic hydrolysis (EH) with commercially available phosphatases was used to characterize phosphorus (P) compounds in extracts of the dominant aquatic macrophytes and algae in a eutrophic lake. Total extractable organic P (Po) conc...

journal_title：Scientific reports

authors： Feng W,Zhu Y,Wu F,He Z,Zhang C,Giesy JP

更新日期：2016-11-16 00:00:00

abstract：:Invasive pulmonary Aspergillosis is a leading cause of morbidity and mortality in immunosuppressed patients and treatment outcomes using oral antifungal triazoles remain suboptimal. Here we show that combining topical treatment using PC945, a novel inhaled triazole, with systemic treatment using known triazoles demons...

journal_title：Scientific reports

authors： Colley T,Sehra G,Daly L,Kimura G,Nakaoki T,Nishimoto Y,Kizawa Y,Strong P,Rapeport G,Ito K

更新日期：2019-07-01 00:00:00

abstract：:Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water deficit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water deficit and ABA induce expression of some RD22-like proteins. This study aimed to evaluate the effect of water deficit and exogenous ABA...

journal_title：Scientific reports

authors： Phillips K,Ludidi N

更新日期：2017-08-18 00:00:00

abstract：:We introduce a simple criterion to identify two-dimensional (2D) materials based on the comparison between experimental lattice constants and lattice constants mainly obtained from Materials-Project (MP) density functional theory (DFT) calculation repository. Specifically, if the relative difference between the two la...

journal_title：Scientific reports

authors： Choudhary K,Kalish I,Beams R,Tavazza F

更新日期：2017-07-12 00:00:00

abstract：:A high-resolution genetic map is a useful tool for assaying genomic structural variation and clarifying the evolution of polyploid cotton. A total of 36956 SSRs, including 11289 released in previous studies and 25567 which were newly developed based on the genome sequences of G. arboreum and G. raimondii, were utilize...

journal_title：Scientific reports

authors： Wang WW,Tan ZY,Xu YQ,Zhu AA,Li Y,Yao J,Tian R,Fang XM,Liu XY,Tian YM,Teng ZH,Zhang J,Liu DJ,Liu DX,Shang HH,Liu F,Zhang ZS

更新日期：2017-08-09 00:00:00

abstract：:First discovered in rural areas of middle-eastern China in 2009, severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonosis affecting hundreds of cases reported in China each year. Using the national surveillance data from 2010 to 2013, we conducted this retrospective epidemiological study a...

journal_title：Scientific reports

authors： Liu K,Zhou H,Sun RX,Yao HW,Li Y,Wang LP,Di Mu,Li XL,Yang Y,Gray GC,Cui N,Yin WW,Fang LQ,Yu HJ,Cao WC

更新日期：2015-04-23 00:00:00

abstract：:Relocation of earthquakes recorded by the agency for meteorology, climatology and geophysics (BMKG) in Indonesia and inversions of global positioning system (GPS) data reveal clear seismic gaps to the south of the island of Java. These gaps may be related to potential sources of future megathrust earthquakes in the re...

journal_title：Scientific reports

authors： Widiyantoro S,Gunawan E,Muhari A,Rawlinson N,Mori J,Hanifa NR,Susilo S,Supendi P,Shiddiqi HA,Nugraha AD,Putra HE

更新日期：2020-09-17 00:00:00

abstract：:There is relatively little literature on adjuvant radiotherapy after radical nephroureterectomy with bladder cuff excision (RNU) for patients with upper tract urothelial carcinoma (UTUC). This study was designed to determine the efficacy of adjuvant radiotherapy for patients with pT3N0M0 UTUC. We retrospectively revie...

journal_title：Scientific reports

authors： Huang YC,Chang YH,Chiu KH,Shindel AW,Lai CH

更新日期：2016-12-02 00:00:00

abstract：:We present a prototype for conducting rapid, inexpensive and point-of-care-compatible nucleic acid amplification tests (NAATs) for tuberculosis (TB). The fluorescent isothermal paper-and-plastic NAAT (FLIPP-NAAT) uses paper-based loop mediated isothermal amplification (LAMP) for DNA detection. The cost of materials re...

journal_title：Scientific reports

authors： Kaur N,Michael JS,Toley BJ

更新日期：2019-10-25 00:00:00

abstract：:The cardiac neural crest cells (cNCCs) and the second heart field (SHF) play key roles in development of the cardiac outflow tract (OFT) for establishment of completely separated pulmonary and systemic circulations in vertebrates. A neurovascular guiding factor, Semaphorin 3c (Sema3c), is required for the development ...

journal_title：Scientific reports

authors： Kodo K,Shibata S,Miyagawa-Tomita S,Ong SG,Takahashi H,Kume T,Okano H,Matsuoka R,Yamagishi H

更新日期：2017-07-28 00:00:00

abstract：:This is the first study to demonstrate that colour transformations in the volume of a photochromic material (PM) are induced at the intersections of two control light channels, one controlling PM colouration and the other controlling decolouration. Thus, PM colouration is induced by position selectivity, and therefore...

journal_title：Scientific reports

authors： Hirayama R,Shiraki A,Naruse M,Nakamura S,Nakayama H,Kakue T,Shimobaba T,Ito T

更新日期：2016-08-16 00:00:00

abstract：:Multifunctional materials with more than two good properties are widely required in modern industries. However, some properties are often trade-off with each other by single microstructural designation. For example, nanostructured materials have high strength, but low ductility and thermal stability. Here by means of ...

journal_title：Scientific reports

authors： Zhang YS,Zhao YH,Zhang W,Lu JW,Hu JJ,Huo WT,Zhang PX

更新日期：2017-01-06 00:00:00

abstract：:SIRT1, the NAD+-dependent protein deacetylase, controls cell-cycle progression and apoptosis by suppressing p53 tumour suppressor. Although SIRT1 is known to be phosphorylated by JNK1 upon oxidative stress and subsequently down-regulated, it still remains elusive how SIRT1 stability and activity are controlled. Here, ...

journal_title：Scientific reports

authors： Kim M,Kwon YE,Song JO,Bae SJ,Seol JH

更新日期：2016-11-24 00:00:00

abstract：:Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy. A proteomic study in muscles with reduced PABPN1 levels suggested dysregula...

journal_title：Scientific reports

authors： Olie CS,van der Wal E,Domagoj C,Maton L,de Greef JC,Lin IH,Chen YF,Kareem E,Penninger JM,Kessler BM,Raz V

更新日期：2020-10-19 00:00:00

abstract：:Our previous study suggested that microtubule network alteration affects the process of glycolysis in cardiomyocytes (CMs) via the regulation of hypoxia-inducible factor (HIF)-1α during the early stages of hypoxia. However, little is known regarding the underlying mechanisms of microtubule network alteration-induced c...

journal_title：Scientific reports

authors： Jiang X,Zhang D,Zhang H,Huang Y,Teng M

更新日期：2015-03-17 00:00:00

abstract：:We consider the electromagnetic response of a topological Weyl semimetal (TWS) with a pair of Weyl nodes in the bulk and corresponding Fermi arcs in the surface Brillouin zone. We compute the frequency-dependent complex conductivities σαβ(ω) and also take into account the modification of Maxwell equations by the topol...

journal_title：Scientific reports

authors： Kargarian M,Randeria M,Trivedi N

更新日期：2015-08-03 00:00:00

abstract：:We present the design and performance characterization of a Faraday laser directly lasing on the Rb 1529 nm transition (Rb, 5P 3/2 - 4D 5/2) with high stability, narrow spectral linewidth and low cost. This system does not need an additional frequency-stabilized pump laser as a prerequisite to preparing Rb atom from 5...

journal_title：Scientific reports

authors： Chang P,Peng H,Zhang S,Chen Z,Luo B,Chen J,Guo H

更新日期：2017-08-21 00:00:00

abstract：:We have proposed a scheme and presented the first experimental demonstration of acoustic illusion, by using anisotropic metamaterials to manipulate the acoustic field near boundaries of arbitrary curved geometry. Numerical simulations and experimental results show that in the presence of an illusion cloak, any object ...

journal_title：Scientific reports

authors： Kan W,Liang B,Zhu X,Li R,Zou X,Wu H,Yang J,Cheng J

更新日期：2013-01-01 00:00:00

abstract：:Phagocytosis is a required mechanism for the defense against pathogens. Staphylococcus aureus, an important bacterial pathogen, can promptly escape from phagosomes and proliferate within the cytoplasm of host. However, the mechanism of phagocytosis against S. aureus has not been intensively investigated. In this study...

journal_title：Scientific reports

authors： Zhu F,Zhou Y,Jiang C,Zhang X

更新日期：2015-10-07 00:00:00

abstract：:Biomarkers reflecting the extent of Mycobacterium tuberculosis-induced pathology and normalization during anti-tuberculosis treatment (ATT) would considerably facilitate trials of new treatment regimens and the identification of patients with treatment failure. Therefore, in a cohort of 99 Indian children with intrath...

journal_title：Scientific reports

authors： Jenum S,Bakken R,Dhanasekaran S,Mukherjee A,Lodha R,Singh S,Singh V,Haks MC,Ottenhoff TH,Kabra SK,Doherty TM,Ritz C,Grewal HM

更新日期：2016-12-12 00:00:00

abstract：:Ophidian accidents are considered an important neglected tropical disease by the World Health Organization. Particularly in Latin America, Bothrops snakes are responsible for the majority of the snakebite envenomings that are not efficiently treated by conventional serum therapy. Thus, the search for simple and effici...

journal_title：Scientific reports

authors： Salvador GHM,Cardoso FF,Gomes AA,Cavalcante WLG,Gallacci M,Fontes MRM

更新日期：2019-01-24 00:00:00