BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome.

abstract：:Herbal medicines usually contain a large group of chemical components, which may be transformed into more complex metabolites in vivo. In this study, we proposed a knowledge-transmitting strategy for metabolites identification of compound formulas. Gegen-Qinlian Decoction (GQD) is a classical formula in traditional Ch...

journal_title：Scientific reports

authors： Qiao X,Wang Q,Wang S,Miao WJ,Li YJ,Xiang C,Guo DA,Ye M

更新日期：2016-12-20 00:00:00

abstract：:Dental caries is an important public health problem worldwide. This study aims to prove how preventive therapies reduce the onset of caries in adult patients, and to identify patients with high or low risk of caries by using Classification and Regression Trees based survival analysis (survival CART). A clinical data s...

journal_title：Scientific reports

authors： Arino M,Ito A,Fujiki S,Sugiyama S,Hayashi M

更新日期：2016-07-06 00:00:00

abstract：:The ability to wirelessly power electrical devices is becoming of greater urgency as a component of energy conservation and sustainability efforts. Due to health and safety concerns, most wireless power transfer (WPT) schemes utilize very low frequency, quasi-static, magnetic fields; power transfer occurs via magneto-...

journal_title：Scientific reports

authors： Lipworth G,Ensworth J,Seetharam K,Huang D,Lee JS,Schmalenberg P,Nomura T,Reynolds MS,Smith DR,Urzhumov Y

更新日期：2014-01-10 00:00:00

abstract：:Layered-structure materials are currently relevant given their quasi-2D nature. Knowledge of their physical properties is currently of major interest. Niobium ditelluride possesses a monoclinic layered-structure with a distortion in the tellurium planes. This structural complexity has hindered the determination of its...

journal_title：Scientific reports

authors： Barajas-Aguilar AH,Irwin JC,Garay-Tapia AM,Schwarz T,Paraguay Delgado F,Brodersen PM,Prinja R,Kherani N,Jiménez Sandoval SJ

更新日期：2018-11-19 00:00:00

abstract：:Yeast Cdc48 is a well-conserved, essential chaperone of ATPases associated with diverse cellular activity (AAA) proteins, which recognizes substrate proteins and modulates their conformations to carry out many cellular processes. However, the fundamental mechanisms underlying the diverse pivotal roles of Cdc48 remain ...

journal_title：Scientific reports

authors： Esaki M,Islam MT,Tani N,Ogura T

更新日期：2017-07-14 00:00:00

abstract：:Plasmodiophora brassicae causes clubroot disease in cruciferous. In this report, lipid droplets were observed in the resting spores of P. brassicae. 295 lipid droplet-associated proteins were identified and categorized into nine groups. Transcriptome analysis of these proteins during three different zoosporic stages r...

journal_title：Scientific reports

authors： Bi K,He Z,Gao Z,Zhao Y,Fu Y,Cheng J,Xie J,Jiang D,Chen T

更新日期：2016-11-22 00:00:00

abstract：:Diabetes is expected to accelerate age-related ganglion cell-inner plexiform layer (GC-IPL) loss, but there is limited information on the rate of reduction in GC-IPL thicknesses. We aimed to evaluate the reduction rate of GC-IPL thickness in diabetic patients, and to compare the rates between patients without and with...

journal_title：Scientific reports

authors： Lim HB,Shin YI,Lee MW,Koo H,Lee WH,Kim JY

更新日期：2020-01-30 00:00:00

abstract：:Helicobacter pylori is presumed to infect gastric tissue via the oral cavity in childhood, whereas risk factors for H. pylori infection in the oral cavity are unknown. In this study, we analysed the effects of Streptococcus mutans, a major cariogenic bacterial species, on H. pylori colonisation in the oral cavity, as ...

journal_title：Scientific reports

authors： Nomura R,Kadota T,Ogaya Y,Matayoshi S,Iwashita N,Okawa R,Nakano K

更新日期：2020-07-27 00:00:00

abstract：:This study was aimed to assess the relationship of intraocular forward scattering, corneal backward scattering, and corneal higher-order aberrations (HOAs) with corrected distance visual acuity (CDVA) in eyes with granular corneal dystrophy (GCD). We retrospectively examined forty two eyes of 42 consecutive patients w...

journal_title：Scientific reports

authors： Kamiya K,Kobashi H,Igarashi A,Shoji N,Shimizu K

更新日期：2016-04-18 00:00:00

abstract：:Target-guided synthesis is an approach to drug discovery that allows the target to self-assemble its own binding agents. So far, target-guided synthesis and especially in situ click chemistry have attracted extensive attention and have led to the identification of highly potent inhibitors for proteins. In this study, ...

journal_title：Scientific reports

authors： Hu MH,Chen X,Chen SB,Ou TM,Yao M,Gu LQ,Huang ZS,Tan JH

更新日期：2015-11-25 00:00:00

abstract：:Associated with global warming, drought has destructive influences on agriculture and ecosystems, especially in the fragile Qinghai-Tibet Plateau (QTP). This study investigated spatial-temporal patterns of meteorological drought in the QTP and its surrounding areas and made an attempt to explore the relationship betwe...

journal_title：Scientific reports

authors： Feng W,Lu H,Yao T,Yu Q

更新日期：2020-08-31 00:00:00

abstract：:Synthetic analogues of mycobacterial trehalose-dimycolate such as trehalose acyl esters have been proposed as novel adjuvants for vaccination. They induce an immune response by binding to the macrophage C-type lectin receptor Mincle. The binding site of trehalose is known, but there is yet only very limited structural...

journal_title：Scientific reports

authors： Söldner CA,Horn AHC,Sticht H

更新日期：2018-03-29 00:00:00

abstract：:Present study focuses on rainfall over Western Ghats (WG), a complex topographic region (elevation > 500 m) of India to evaluate and to better understand the satellite behavior in contrast with a flat region (FR) (elevation < 500 m) of central India from 1998 to 2016 using the combinatory data sets of TMPA and IMERG (...

journal_title：Scientific reports

authors： Thakur MK,Kumar TVL,Koteswara Rao K,Barbosa H,Rao VB

更新日期：2019-10-30 00:00:00

abstract：:This study aims to evaluate the necessity of urgent neuroimaging for emergency admissions exhibiting symptomatology of profound hyponatremia. We retrospectively analyzed the medical records of all patients admitted to the emergency room of the University Hospital Münster from 2010 to 2014 with a serum sodium value < 1...

journal_title：Scientific reports

authors： Bokemeyer A,Dziewas R,Wiendl H,Schwindt W,Bicsán P,Kümpers P,Pavenstädt H

更新日期：2017-05-16 00:00:00

abstract：:Amorphous solid dispersion (ASD) is a widely employed formulation technique for drugs with poor aqueous solubility. Polymers are integral components of ASDs, but mechanisms by which polymers lead to the generation and maintenance of supersaturated solutions, which enhance oral absorption in vivo, are poorly understood...

journal_title：Scientific reports

authors： Wilson VR,Lou X,Osterling DJ,Stolarik DF,Jenkins GJ,Nichols BLB,Dong Y,Edgar KJ,Zhang GGZ,Taylor LS

更新日期：2020-10-28 00:00:00

abstract：:The vast majority of antibody-drug conjugates (ADC) are prepared through amine-to-thiol conjugation. To date, N-Succinimidyl-4-(maleimidomethyl) cyclohexanecarboxylate (SMCC) has been one of the most frequently applied reagents for the preparation of ADC and other functional conjugates. However, SMCC-based conjugates ...

journal_title：Scientific reports

authors： Dovgan I,Kolodych S,Koniev O,Wagner A

更新日期：2016-08-09 00:00:00

abstract：:The accelerated discovery of disease-related genes emerging from genomic studies has strained the capacity of traditional genetically engineered mouse models (GEMMs) to provide in-vivo validation. Direct, somatic, genetic engineering approaches allow for accelerated and flexible genetic manipulation and represent an a...

journal_title：Scientific reports

authors： Espana-Agusti J,Tuveson DA,Adams DJ,Matakidou A

更新日期：2015-06-05 00:00:00

abstract：:Association of a high-serum ferritin with poor outcome showed that iron might play a detrimental role in the brain after intracerebral hemorrhage (ICH). Here, we investigated changes in serum iron, ferritin, transferrin (Tf) and ceruloplasmin (CP) in patients with ICH (n = 100) at day 1 (admission), 3, 7, 14 and 21 an...

journal_title：Scientific reports

authors： Yang G,Hu R,Zhang C,Qian C,Luo QQ,Yung WH,Ke Y,Feng H,Qian ZM

更新日期：2016-02-22 00:00:00

abstract：:We describe a high resolution laser polarimeter built from commodity optical components. The optical rotation angle is determined by measuring the phase difference between two harmonically modulated polarised laser beams - an 'object beam' that passes through the sample under test and a 'reference beam' that bypasses ...

journal_title：Scientific reports

authors： Harvie AJ,Phillips TW,deMello JC

更新日期：2020-03-25 00:00:00

abstract：:We introduce a concept that enables parallelized three-dimensional imaging throughout large volumes with isotropic 300-350 nm resolution. By staggering high aspect ratio illumination beams laterally and axially within the depth of focus of a digitally scanned light-sheet fluorescence microscope (LSFM), multiple image ...

journal_title：Scientific reports

authors： Dean KM,Fiolka R

更新日期：2017-08-24 00:00:00

abstract：:The influence of dose rate on radiation cataractogenesis has yet to be extensively studied. One recent epidemiological investigation suggested that protracted radiation exposure increases radiation-induced cataract risk: cumulative doses of radiation mostly <100 mGy received by US radiologic technologists over 5 years...

journal_title：Scientific reports

authors： Barnard SGR,McCarron R,Moquet J,Quinlan R,Ainsbury E

更新日期：2019-07-18 00:00:00

abstract：:Coleoid cephalopods have an elaborate camera eye whereas nautiloids have primitive pinhole eye without lens and cornea. The Nautilus pinhole eye provides a unique example to explore the module of lens formation and its evolutionary mechanism. Here, we conducted an RNA-seq study of developing eyes of Nautilus and pygmy...

journal_title：Scientific reports

authors： Ogura A,Yoshida MA,Moritaki T,Okuda Y,Sese J,Shimizu KK,Sousounis K,Tsonis PA

更新日期：2013-01-01 00:00:00

abstract：:A Chemical absorption-bioelectrochemical reduction (CABER) system is based on Chemical absorption-biological reduction (CABR) system, which aims at NO removal and has been studied in many of our previous works. In this paper, we applied polypyrrole (PPy) on the electrode of bioelectrochemical reactor (BER) of CABER sy...

journal_title：Scientific reports

authors： Guo T,Zhang C,Zhao J,Ma C,Li S,Li W

更新日期：2019-09-10 00:00:00

abstract：:Tin selenide has attracted much research interest due to its unprecedentedly high thermoelectric figure of merit (ZT). For real applications, it is desirable to increase the ZT value in the lower-temperature range, as the peak ZT value currently exists near the melting point. It is shown in this paper that the structu...

journal_title：Scientific reports

authors： Yu H,Dai S,Chen Y

更新日期：2016-05-19 00:00:00

abstract：:Osteoclasts are specialised bone resorbing cells that control both physiological and pathological bone turnover. Functional changes in the differentiation and activity of osteoclasts are accompanied by active metabolic reprogramming. However, the biological significance and the in vivo relevance of these events has re...

journal_title：Scientific reports

authors： Taubmann J,Krishnacoumar B,Böhm C,Faas M,Müller DIH,Adam S,Stoll C,Böttcher M,Mougiakakos D,Sonnewald U,Hofmann J,Schett G,Krönke G,Scholtysek C

更新日期：2020-12-03 00:00:00

abstract：:VvhA, a virulent factor of Vibrio (V.) vulnificus, induces acute cell death in a destructive manner. Autophagy plays an important role in cell death, but the functional role of VvhA in autophagy-related cell death has not been elucidated yet. We found that rVvhA significantly increased LC3 puncta formation and autopha...

journal_title：Scientific reports

authors： Song EJ,Lee SJ,Lim HS,Kim JS,Jang KK,Choi SH,Han HJ

更新日期：2016-06-02 00:00:00

abstract：:The realization of reliable quantum channels, able to transfer a quantum state with high fidelity, is a fundamental step in the construction of scalable quantum devices. In this paper we describe a transmission scheme based on the genuinely quantum effect known as Bloch oscillations. The proposed protocol makes it pos...

journal_title：Scientific reports

authors： Tamascelli D,Olivares S,Rossotti S,Osellame R,Paris MG

更新日期：2016-05-18 00:00:00

abstract：:Mapping near-field profiles and dynamics of surface plasmon polaritons is crucial for understanding their fundamental optical properties and designing miniaturized photonic devices. This requires a spatial resolution on the sub-wavelength scale because the effective polariton wavelength is shorter than free-space exci...

journal_title：Scientific reports

authors： Du L,Lei DY,Yuan G,Fang H,Zhang X,Wang Q,Tang D,Min C,Maier SA,Yuan X

更新日期：2013-10-29 00:00:00

abstract：:Alcohol use disorder (AUD) is a chronic and relapsing disease with a substantial genetic influence. Given the recent discovery of the association of PPM1G methylation with alcohol use disorder (AUD) from a genome-wide methylation study, we sought to verify and extend the previous work of AUD-related impulsivity in a K...

journal_title：Scientific reports

authors： Park CI,Kim HW,Hwang SS,Kang JI,Kim SJ

更新日期：2020-03-26 00:00:00

abstract：:Free-surface vortices have long been studied to develop an understanding of similar rotating flow phenomena observed in nature and technology. However, a complete description of its turbulent three-dimensional flow field still remains elusive. In contrast, the related Taylor-Couette flow system has been well explicate...

journal_title：Scientific reports

authors： Mulligan S,De Cesare G,Casserly J,Sherlock R

更新日期：2018-01-16 00:00:00