Abstract：
:Domestication and selective breeding has resulted in over 1000 extant cattle breeds. Many of these breeds do not excel in important traits but are adapted to local environments. These adaptations are a valuable source of genetic material for efforts to improve commercial breeds. As a step toward this goal we identified candidate regions to be under selection in genomes of nine Russian native cattle breeds adapted to survive in harsh climates. After comparing our data to other breeds of European and Asian origins we found known and novel candidate genes that could potentially be related to domestication, economically important traits and environmental adaptations in cattle. The Russian cattle breed genomes contained regions under putative selection with genes that may be related to adaptations to harsh environments (e.g., AQP5, RAD50, and RETREG1). We found genomic signatures of selective sweeps near key genes related to economically important traits, such as the milk production (e.g., DGAT1, ABCG2), growth (e.g., XKR4), and reproduction (e.g., CSF2). Our data point to candidate genes which should be included in future studies attempting to identify genes to improve the extant breeds and facilitate generation of commercial breeds that fit better into the environments of Russia and other countries with similar climates.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yurchenko AA,Daetwyler HD,Yudin N,Schnabel RD,Vander Jagt CJ,Soloshenko V,Lhasaranov B,Popov R,Taylor JF,Larkin DMdoi
10.1038/s41598-018-31304-wsubject
Has Abstractpub_date
2018-08-28 00:00:00pages
12984issue
1issn
2045-2322pii
10.1038/s41598-018-31304-wjournal_volume
8pub_type
杂志文章abstract：:Currently, the arguments have existed in the strengthening mechanism and microstructural model of the nanocomposite film due to lack of the convincible experimental evidences. In this investigation, the quarternary TiSiCN nanocomposite films with the different C and Si contents are synthesized by the reactive-magnetro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02186-1
更新日期：2017-05-18 00:00:00
abstract：:The current theories of antimalarial mechanism of artemisinin are inadequate to fully explain the observed effects. In our study, "organism-like" formation of Schistosoma hemozoin granules by attaching to and utilizing erythrocytes to form new ones was observed. This indicates that heme iron is transferred from erythr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34463
更新日期：2016-10-03 00:00:00
abstract：:Computational ghost imaging (CGI) achieves single-pixel imaging by using a Spatial Light Modulator (SLM) to generate structured illuminations for spatially resolved information encoding. The imaging speed of CGI is limited by the modulation frequency of available SLMs, and sets back its practical applications. This pa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45325
更新日期：2017-03-30 00:00:00
abstract：:Caloric restriction (CR) is known to promote health and longevity, likely via modification of the gut microbiota (GM). However, functional and metabolic changes induced in the GM during CR are still unidentified. Here, we investigated the short- and long-term effects of CR on the rat GM using a metaproteogenomic appro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33100-y
更新日期：2018-10-03 00:00:00
abstract：:A subwoofer generates the lowest frequency range in loudspeaker systems. Subwoofers are used in audio systems for live concerts, movie theatres, home theatres, gaming consoles, cars, etc. During the last decades, numerical simulations have emerged as a cost- and time-efficient complement to traditional experiments in ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80092-9
更新日期：2021-01-08 00:00:00
abstract：:Sarcopenia is defined as skeletal muscle attenuation and has an association with metabolic syndrome. Metabolic syndrome, which includes obesity, is one of known predictive factors for gastroesophageal reflux disease (GERD). This study aimed to elucidate the association between sarcopenia and GERD. We retrospectively r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56702-6
更新日期：2019-12-27 00:00:00
abstract：:Alzheimer's disease is characterized by neuronal loss and cerebral accumulation of amyloid-β protein (Aβ) and lowering the generation of Aβ is a pivotal approach in the strategy of Alzheimer's disease treatment. Midlife hypertension is a major risk factor for the future onset of sporadic Alzheimer's disease and the us...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12059
更新日期：2015-07-08 00:00:00
abstract：:Terrestrial plants typically take up nutrients through roots or mycorrhizae while freshwater plants additionally utilize leaves. Their nutrient uptake may be enhanced by root hairs whose occurrence is often negatively correlated with mycorrhizal colonization. Seagrasses utilize both leaves and roots and often form roo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28989-4
更新日期：2018-07-17 00:00:00
abstract：:Dyslipidemia in pregnancy are associated with risk of adverse outcomes. As an adverse pregnancy outcome, small-for-gestational-age has been extensively studied in Western countries. However, similar studies have rarely been conducted in Asian countries. Data were derived from 5695 pairs of non-diabetic mothers and neo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76845-1
更新日期：2020-11-16 00:00:00
abstract：:Pearl millet hybrids biofortified with iron (Fe) and zinc (Zn) promise to be part of a long-term strategy to combat micronutrient malnutrition in the arid and semi-arid tropical (SAT) regions of the world. Biofortification through molecular breeding is the way forward to achieving a rapid trait-based breeding strategy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76230-y
更新日期：2020-11-10 00:00:00
abstract：:Wurtzite solid solutions between GaN and ZnO highlight an intriguing paradigm for water splitting into hydrogen and oxygen using solar energy. However, large composition discrepancy often occurs inside the compound owing to the volatile nature of Zn, thereby prescribing rigorous terms on synthetic conditions. Here we ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19060
更新日期：2016-01-12 00:00:00
abstract：:Continuous, as opposed to pulsatile, delivery of hypothalamic gonadotropin-releasing hormone (GnRH) leads to a marked decrease in secretion of pituitary gonadotropins LH and FSH and impairment of reproductive function. Here we studied the expression profile of gonadotropin subunit and GnRH receptor genes in rat pituit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56480-1
更新日期：2019-12-27 00:00:00
abstract：:Upon illumination, a dielectric microsphere (μS) can generate a photonic nanojet (PNJ), which plays a role in the super-resolution imaging of a sample placed in the μS's immediate proximity. Recent microscopy implementations pioneered this concept but, despite the experimental characterization and theoretical modeling...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33604-7
更新日期：2018-10-12 00:00:00
abstract：:A dynamical system is controllable if by imposing appropriate external signals on a subset of its nodes, it can be driven from any initial state to any desired state in finite time. Here we study the impact of various network characteristics on the minimal number of driver nodes required to control a network. We find ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01067
更新日期：2013-01-01 00:00:00
abstract：:Few studies have investigated the relationship between chronic rhinosinusitis (CRS) and erectile dysfunction (ED). This case-control study aimed to investigate the association between CRS and the risk of ED in a large national sample. Tapping Taiwan's National Health Insurance Research Database, we identified people 3...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/srep32195
更新日期：2016-08-31 00:00:00
abstract：:We present active manipulation of the structural vibrations of an elastic body to generate an acoustic illusion. The resultant illusion misrepresents the nature, size and number of objects in the exterior acoustic domain. We demonstrate our technique, herein termed active structural acoustic illusion, using an elastic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66398-8
更新日期：2020-06-17 00:00:00
abstract：:Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal phy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36263
更新日期：2017-04-03 00:00:00
abstract：:Although autoantibody detection has been proposed for diagnosis of colorectal cancer, little is known about their initial production and development correlation with cancer progression. Azoxymethane/dextran sodium sulfate (AOM/DSS)-treated mice developed colon adenocarcinoma in the distal colon similar to human sporad...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02938
更新日期：2013-10-15 00:00:00
abstract：:Here we report exquisitely distinct material properties of primary vascular smooth muscle (VSM) cells isolated from the thoracic aorta of adult (8 months) vs. aged (30 months) F344XBN rats. Individual VSM cells derived from the aged animals showed a tense internal network of the actin cytoskeleton (CSK), exhibiting in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20763-w
更新日期：2018-02-08 00:00:00
abstract：:Using 137Cs and 210Pb dating and multi-proxy evidence from a 41-cm sediment core from Bosten Lake in China, the responses of sediment grain size to environmental changes were reconstructed over the past 150 years. After the end of the Little Ice Age, the climate of the Bosten Lake region became warmer and drier, and t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-57921-y
更新日期：2020-01-22 00:00:00
abstract：:The pathological mechanism of Kashin-Beck disease (KBD), an endemic osteoarthritic disease, remains to be poorly understood. This study was designed to identify signaling pathways and crucial proteins involved in the pathological mechanism of KBD compared with osteoarthritis (OA). The knee cartilage samples were colle...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63932-6
更新日期：2020-04-22 00:00:00
abstract：:In order to design a painless and mechanically durable micro syringe-needle system for biomedical applications, the study of insect stingers is of interest because of their elegant structures and functionalities. In the present work, the structure, mechanical properties and the mechanical behavior during insertion of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33386-y
更新日期：2018-10-08 00:00:00
abstract：:In zebrafish, the role of matrix metalloproteinases (MMPs) in the inflammatory phase of heart regeneration following cryoinjury remains poorly understood. Here, we demonstrated an increase in MMP enzymatic activity and elevated expression of mmp9 and mmp13 in the injured area (IA) of hearts from as early as 1 day post...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25490-w
更新日期：2018-05-08 00:00:00
abstract：:The corrosion of steel in concrete is mainly due to the chemical reaction between the chloride ions and iron ions. Indeed, this is a serious threaten for reinforced concrete structure, especially for the reinforced concrete structure in the sea. So it is urgent and important to protect concrete against chloride ions c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03359
更新日期：2013-11-28 00:00:00
abstract：:Avian influenza viruses (AIV) are classified into 16 hemagglutinin (HA; H1-H16) and 9 neuraminidase (NA; N1-N9) subtypes. All AIV are low pathogenic (LP) in birds, but subtypes H5 and H7 AIV can evolve into highly pathogenic (HP) forms. In the last two decades evolution of HPAIV H7 from LPAIV has been frequently repor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47938-3
更新日期：2019-08-09 00:00:00
abstract：:Decarboxylation of fatty acids over non-noble metal catalysts without added hydrogen was studied. Ni/C catalysts were prepared and exhibited excellent activity and maintenance for decarboxylation. Thereafter, the effects of nickel loading, catalyst loading, temperature, and carbon number on the decarboxylation of fatt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27820
更新日期：2016-06-13 00:00:00
abstract：:Prostate cancer is the most commonly diagnosed cancer in men with African American men disproportionally suffering from the burden of this disease. Biomarkers that could discriminate indolent from aggressive and drug resistance disease are lacking. MicroRNAs are small non-coding RNAs that affect numerous physiological...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46170-3
更新日期：2019-07-05 00:00:00
abstract：:Maoto, a traditional Japanese Kampo medicine, has been used to treat various respiratory diseases, including respiratory infections and influenza. Ephedrine (EPD), the main ingredient in maoto, is also clinically used to treat respiratory diseases. However, the pharmacokinetics and distribution of EPD in the lungs aft...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44098
更新日期：2017-03-08 00:00:00
abstract：:Transgenic sexing strains (TSS) that carry conditional female lethal genes are advantageous for genetic control programs based on the sterile insect technique (SIT). It is desirable if females die early in development as larval diet is a major cost for mass production facilities. This can be achieved by using a gene p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02763-4
更新日期：2017-05-31 00:00:00
abstract：:Neuroimaging studies of the Psychomotor Vigilance Task (PVT) have revealed brain regions involved in attention lapses in sleep-deprived and well-rested adults. Those studies have focused on individual brain regions, rather than integrated brain networks, and have overlooked adolescence, a period of ongoing brain devel...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50180-6
更新日期：2019-09-26 00:00:00
