On the mechanism of renin release during experimental myocardial ischaemia.

abstract：:The effect of marine n-3 polyunsaturated fatty acids on proliferation of human T-cells in vitro was compared to other polyunsaturated, monounsaturated and saturated fatty acids. Monoenes and saturated fatty acids had little effect on T-cell proliferation. Eicosapentaenoic acid and docosahexaenoic acid exerted a strong...

journal_title：European journal of clinical investigation

authors： Søyland E,Nenseter MS,Braathen L,Drevon CA

更新日期：1993-02-01 00:00:00

abstract：:In man, HCl acidosis reduces blood and urinary urea with a concomitant rise in ammonium (NH4+) excretion. Significantly less urea is excreted following NH4Cl administration than following equimolar ingestion of NH4 HCO3. The results of these alterations in nitrogen excretion are interpreted in terms of bicarbonate uti...

journal_title：European journal of clinical investigation

authors： Fine A,Carlyle JE,Bourke E

更新日期：1977-12-01 00:00:00

abstract：:The effect of sequential combined hormone replacement therapy on the susceptibility of low-density lipoprotein to oxidative modification was investigated in a double-blind, randomized placebo-controlled study. Hypercholesterolaemic, postmenopausal women were supplemented with 17 beta-oestradiol and norethisterone acet...

journal_title：European journal of clinical investigation

authors： Nenseter MS,Volden V,Berg T,Drevon CA,Ose L,Tonstad S

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Age is one the factors associated with poor prognosis in acute coronary syndromes (ACS) and elderly patients are a high-risk collective with few parameters for mid-term cardiovascular stratification. We aimed to assess the predictive value of ankle-brachial index (ABI) in patients (> 75 years) for 1-year mor...

journal_title：European journal of clinical investigation

authors： Cordero A,Morillas P,Bertomeu-González V,Quiles J,Soria F,Guindo J,Mazón P,Anguita M,Rodríguez-Padial L,González-Juanatey JR,Bertomeu-Martínez V,en nombre de los investigadores del estudio PAMISCA.

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Carotid ultrasound is a noninvasive tool for risk assessment of coronary artery disease (CAD). There is no consensus on which carotid ultrasound parameter constitutes the best measurement of atherosclerosis. We investigated which model of carotid ultrasound parameters and clinical risk factors (CRF) has the ...

journal_title：European journal of clinical investigation

authors： Wu N,Chen X,Li M,Qu X,Li Y,Xie W,Wu L,Xiang Y,Li Y,Zhong L

更新日期：2018-08-01 00:00:00

abstract：:Immunoreactive parathyroid hormone (PTH) levels and nephrogenous cyclic adenosine monophosphate (cAMP) have been reported to be useful parameters in the diagnosis of hyperparathyroidism. Measurements in hyperparathyroid patients usually give values above the normal range when PTH is measured with a carboxyterminal rad...

journal_title：European journal of clinical investigation

authors： Bill G,Jacquet AF,Burckhardt P

更新日期：1984-06-01 00:00:00

abstract：:The release of PGI2-like activity into the circulation in response to cholinergic agonists and modification of this response by beta-adrenergic antagonists was investigated in anaesthetized cats and healthy humans. Antiaggregatory activity in the arterial blood was continuously assayed by measuring platelet aggregatio...

journal_title：European journal of clinical investigation

authors： Swies J,Radomski M,Dembińska-Kieć A,Korbut R,Gryglewski RJ,Brandt R,Nowak J

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Inflammation is an established contributor in atherosclerosis and several other common diseases including diabetes. Therefore the study was to investigate how inflammatory factors affect lipid metabolism during recovery from hyperinsulinaemia in healthy individuals. MATERIALS AND METHODS:A total of 22 healt...

journal_title：European journal of clinical investigation

authors： Heliövaara MK,Teppo AM,Karonen SL,Ebeling P

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Soluble TWEAK (sTWEAK) and asymmetric dimethyl arginine (ADMA) concentrations have been associated with endothelial function in patients with chronic kidney disease (CKD). We tested the hypothesis that the improvement in endothelial function observed after renal transplantation is directly linked to the norm...

journal_title：European journal of clinical investigation

authors： Yilmaz MI,Sonmez A,Saglam M,Yaman H,Unal HU,Gok M,Cetinkaya H,Eyileten T,Oguz Y,Sari S,Yildirim AO,Vural A,Carrero JJ,Blanco-Colio LM

更新日期：2013-12-01 00:00:00

abstract：:Moderate and progressive hypertension was produced experimentally in rats by progressive aortic constriction. The progression of the stenosis was assessed by the differences of pressure across the stenosis. Haemodynamic studies were performed 15, 30 and 60 days after the ligature was placed or after sham operation. Fi...

journal_title：European journal of clinical investigation

authors： Martín-Paredero V,Casado S,López-Novoa JM

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:  Hyperlipidaemia, hyperglycaemia and hyperinsulinaemia, hallmarks of the postprandial state, have been also associated with increased oxidative stress and lipoprotein oxidation contributing to vascular injury and atherosclerosis. However, the specific links among metabolic disorders, postprandial state, ins...

journal_title：European journal of clinical investigation

authors： D'Archivio M,Annuzzi G,Varì R,Filesi C,Giacco R,Scazzocchio B,Santangelo C,Giovannini C,Rivellese AA,Masella R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The sympathetic nervous exerts a key role in cardiovascular homeostasis control by regulating cardiac output, systemic vascular resistance, heart rate and blood pressure. MATERIALS AND METHODS:Data collected during the past 30 years have unequivocally shown that in a considerable number of cardiovascular as...

journal_title：European journal of clinical investigation

authors： Grassi G,Seravalle G,Mancia G

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Arterial calcification (AC) is a major health problem associated with extreme morbidity and a shortened survival. It is currently without any effective treatment. ATP and the purinergic system in general are now emerging as being important in the pathogenesis of AC and potentially provide a new focus for nov...

journal_title：European journal of clinical investigation

authors： Fish RS,Klootwijk E,Tam FW,Kleta R,Wheeler DC,Unwin RJ,Norman J

更新日期：2013-04-01 00:00:00

abstract：:Combined 47Calcium kinetic and calcium balance studies with correction for dermal calcium loss were performed in thirteen patients with primary hyperparathyroidism (PHP), in whom serum bone-Gla-protein (S-BGP) was measured, and in ten matched controls. Dietary calcium was normal in PHP but both net (7.9 +/- 1.4 mmol C...

journal_title：European journal of clinical investigation

authors： Charles P,Mosekilde L,Jensen FT

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Lipoprotein(a) [Lp(a)] is an important cardiovascular risk factor in the general population. However, prospective data on the vascular risk conferred by Lp(a) in patients with diabetes mellitus are scarce and controversial. It is not known whether the diabetic state affects the association of Lp(a) with vasc...

journal_title：European journal of clinical investigation

authors： Saely CH,Koch L,Schmid F,Marte T,Aczel S,Langer P,Hoefle G,Drexel H

更新日期：2006-02-01 00:00:00

abstract：:With advancing age both sexes have an increased incidence of osteoporotic fractures, although fractures are more common in women than in men. Whereas in women several potential risk factors have been identified, less is known about osteoporosis in men. A total of 27 Austrian men (mean age: 65 +/- 2 years) with atrauma...

journal_title：European journal of clinical investigation

authors： Resch H,Pietschmann P,Woloszczuk W,Krexner E,Bernecker P,Willvonseder R

更新日期：1992-08-01 00:00:00

abstract：:The effect of propranolol 160-640 mg/day for 3 months on the accelerated loss of bone matrix and mineral in hyperthyroidism was studied in seventeen patients. A rise in serum thyroxine (P less than 0.01) during the first 3 weeks was followed by a fall (P less than 0.02). Serum triiodothyronine declined during the stud...

journal_title：European journal of clinical investigation

authors： Mosekilde L,Jastrup B,Melsen F,Lund B,Lund B,Sørensen OH,Nielsen HE,Yde H

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) need regular monitoring, usually by blood urea and creatinine measurements, needing venepuncture, frequent attendances and a healthcare professional, with significant inconvenience. Noninvasive monitoring will potentially simplify and improve monitoring. We tested t...

journal_title：European journal of clinical investigation

authors： Ebah LM,Read I,Sayce A,Morgan J,Chaloner C,Brenchley P,Mitra S

更新日期：2012-08-01 00:00:00

abstract：:We have examined the impact of race and positive family history of type 2 diabetes on glucose/insulin dynamics and the two components of glucose disposal in healthy, first-degree relatives of black and white American patients with type 2 diabetes mellitus who are at a greater risk from the disease and their healthy co...

journal_title：European journal of clinical investigation

authors： Osei K,Cottrell DA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Na+,K(+)-ATPase activity was evaluated in relation to membrane composition and molecular organization in erythrocyte membranes from obese patients by the amphyphylic molecule 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan). Its possible relationship with fat distribution and hyperinsulinaemia was also inv...

journal_title：European journal of clinical investigation

authors： Faloia E,Garrapa GG,Martarelli D,Camilloni MA,Lucarelli G,Staffolani R,Mantero F,Curatola G,Mazzanti L

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Low blood levels of antioxidants are associated with an increased risk of developing coronary artery disease. Lipophilic antioxidants are transported in lipoproteins, and hypolipidaemic therapy may therefore alter their blood concentrations. METHODS:The present randomized, placebo-controlled cross-over stud...

journal_title：European journal of clinical investigation

authors： Aberg F,Appelkvist EL,Bröijersén A,Eriksson M,Angelin B,Hjemdahl P,Dallner G

更新日期：1998-03-01 00:00:00

abstract：:The aim of this work is to evaluate whether type 2 diabetes mellitus, obesity and arterial hypertension, three conditions characterized by the presence of insulin resistance, share some common genetic markers. A potential candidate is the Na+/H+ antiporter, the increased activity of which is considered a marker of ess...

journal_title：European journal of clinical investigation

authors： Ghigo D,Alessio P,Burzacca S,Costamagna C,Anfossi G,Cavalot F,Bosia A,Trovati M

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:An earlier report described that transgenic mice ubiquitously expressing cryptochrome1 (CRY1) with a mutation in cystein414 (CRY1-AP Tg mice) display diabetes mellitus in addition to anomalous circadian behaviours. This study examined characteristic aspects of symptoms to clarify the diabetes type and pathog...

journal_title：European journal of clinical investigation

authors： Okano S,Hayasaka K,Igarashi M,Iwai H,Togashi Y,Nakajima O

更新日期：2010-11-01 00:00:00

abstract：:The serum concentrations of collagen type IV,7S, collagen type IV,nc1, and aminoterminal type III procollagen peptide immunoreactive components were measured by means of specific radioimmunoassays during development of granulation tissue in rats. The results were compared with tissue deposition of basement membranes a...

journal_title：European journal of clinical investigation

authors： Hørslev-Petersen K,Pedersen LR,Bentsen KD,Brocks D,Garbarsch C,Kim KY,Hahn EG,Schuppan D,Lorenzen I

更新日期：1988-08-01 00:00:00

abstract：:Plasma glucose concentration is the best predictor for the development of non-insulin-dependent diabetes mellitus (NIDDM). However, obesity is also a recognized risk factor for development of the disease, and is easier to track over time. Thus obesity could be of considerable clinical importance as a predictor of diab...

journal_title：European journal of clinical investigation

authors： Ferrannini E,Camastra S

更新日期：1998-09-01 00:00:00

abstract：AIMS:Obesity, diabetes and cardiovascular disease are associated with COVID-19 risk and severity. Because epicardial adipose tissue (EAT) expresses ACE2, we wanted to identify the main factors associated with ACE2 levels and its cleavage enzyme, ADAM17, in epicardial fat. MATERIALS AND METHODS:Epicardial and subcutane...

journal_title：European journal of clinical investigation

authors： Couselo-Seijas M,Almengló C,M Agra-Bermejo R,Luis Fernandez Á,Alvarez E,R González-Juanatey J,Eiras S

更新日期：2020-11-29 00:00:00

abstract：BACKGROUND:Early detection of fungal infection is essential for beginning of prompt and specific therapy. In this study we describe a rapid and sensitive procedure to detect, by polymerase chain reaction (PCR) assays, a wide range of medically important opportunistic and pathogenic fungi in dermal specimens from dermat...

journal_title：European journal of clinical investigation

authors： Turin L,Riva F,Galbiati G,Cainelli T

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Several clinical trials have suggested that a metabolic cocktail of glucose-insulin-potassium (GIK) decreases mortality rates in patients with acute myocardial infarction (AMI). It has also been reported that Fas-mediated apoptosis plays an important role in ischaemic/reperfusion injury in the rat model. Thi...

journal_title：European journal of clinical investigation

authors： Zhang L,Zhang L,Li YH,Zhang HY,Chen ML,Gao MM,Hu AH,Yang HS,Yang HS

更新日期：2005-03-01 00:00:00

abstract：:The aim of this research was to study exogenous prostacyclin effect on urinary kallikrein excretion (UKK) in man, to define whether prostacyclin-induced renin release and/or endogenously released cyclooxygenase products were responsible for prostacyclin-induced enhancement of UKK, to determine furosemide effect on UKK...

journal_title：European journal of clinical investigation

authors： Pierucci A,Simonetti BM,Ciabattoni G,Taggi F,Morabito S,Vastano S,Pugliese F

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:The importance of ascorbate on the production of extracellular matrix proteins (as elastin and collagens) is now well documented, but no studies have been published concerning its effects on fibronectin biosynthesis. Fibronectin is important for cell attachment and for proliferation. MATERIALS AND METHODS:T...

journal_title：European journal of clinical investigation

authors： Péterszegi G,Dagonet FB,Labat-Robert J,Robert L

更新日期：2002-05-01 00:00:00