Inflammation affects lipid metabolism during recovery from hyperinsulinaemia.

abstract：BACKGROUND:Infiltration of white adipose tissue (WAT) by inflammatory cells in obesity is considered to be a key event in the development of insulin resistance. Recently, mast cells (MCs) have been identified as new players in the pathogenesis of obesity. We aimed to investigate the relationship between MCs and various...

journal_title：European journal of clinical investigation

authors： Einwallner E,Kiefer FW,Di Caro G,Orthofer M,Witzeneder N,Hörmann G,Itariu B,Zeyda M,Penninger JM,Stulnig TM,Esterbauer H,Todoric J

更新日期：2016-11-01 00:00:00

abstract：:In twenty-five outpatients with essential hypertension, the relevance of renal kallikrein excretion for inter-individual differences in the blood pressure response to changes in dietary sodium intake was investigated. The patients were studied during 2 weeks of high (300 mmol) and 2 weeks of low (50-100 mmol) sodium i...

journal_title：European journal of clinical investigation

authors： Koolen MI,Daha MR,van Brummelen P

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the prevalence of lumbar spondylolisthesis (SPL) in patients suffering from low back pain (LBP) with or without rheumatoid arthritis (RA) and to identify potential factors associated with SPL in patients with RA. METHODS:We performed a case-control study. Cases and contro...

journal_title：European journal of clinical investigation

authors： Hagege B,Tubach F,Alfaiate T,Forien M,Dieudé P,Ottaviani S

更新日期：2018-09-01 00:00:00

abstract：:Moderate and progressive hypertension was produced experimentally in rats by progressive aortic constriction. The progression of the stenosis was assessed by the differences of pressure across the stenosis. Haemodynamic studies were performed 15, 30 and 60 days after the ligature was placed or after sham operation. Fi...

journal_title：European journal of clinical investigation

authors： Martín-Paredero V,Casado S,López-Novoa JM

更新日期：1984-08-01 00:00:00

abstract：:In this study the muscarinic receptor antagonist atropine and the cholecystokinin (CCK)-A receptor antagonist loxiglumide were used to investigate the relative importance of cholinergic and CCK-mediated regulation of intestinal phase antro-pyloro-duodenal motility. Plasma levels of gastrointestinal hormones [pancreati...

journal_title：European journal of clinical investigation

authors： Katschinski M,Schirra J,Begliner C,Langbein S,Wank U,D'Amato M,Arnold R

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Subclinical hypothyroidism may adversely affect the development of cardiovascular disease (CVD). Less is known about the role of low-normal thyroid function, that is higher thyroid-stimulating hormone and/or lower free thyroxine levels within the euthyroid reference range, in the development of cardio-metabo...

journal_title：European journal of clinical investigation

authors： van Tienhoven-Wind LJ,Dullaart RP

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Metastatic pheochromocytomas (PCs) and paragangliomas (PGLs) are rare neuroendocrine tumours with a strong genetic background. DESIGN:We searched the PubMed database through February 2015 to identify studies characterizing metastatic PCs/PGLs as well as currently established and evolving therapies. RESULTS...

journal_title：European journal of clinical investigation

authors： Angelousi A,Kassi E,Zografos G,Kaltsas G

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Morpholinosydnonimine, a nitric oxide (NO) donor, has been reported to inhibit insulin release in isolated pancreatic islets. We studied whether transdermal application of nitroglycerin, another NO donor widely used for angina prophylaxis, influenced glucose-stimulated insulin release in healthy, young, male...

journal_title：European journal of clinical investigation

authors： Kovacs P,Szilvassy Z,Hegyi P,Nemeth J,Ferdinandy P,Tosaki A

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The platelet-to-lymphocyte ratio (PLR) has been found to predict clinical outcomes in borderline ovarian tumours and the other genital neoplasms. However, its prognostic value in patients with ovarian cancer remains controversial. The aim of this study was to assess its prognostic value in ovarian cancer. M...

journal_title：European journal of clinical investigation

authors： Tian C,Song W,Tian X,Sun Y

更新日期：2018-05-01 00:00:00

abstract：:Fibronectin is a glycoprotein found in body fluids, loose connective tissue matrix and in basement membranes. Fibronectin in rheumatoid arthritis synovial fluid was immunologically indistinguishable from the plasma form, as shown by double-diffusion analysis. Fibronectin isolated from rheumatoid synovial fluid by affi...

journal_title：European journal of clinical investigation

authors： Vartio T,Vaheri A,Von Essen R,Isomäki H,Stenman S

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:To reveal detailed histopathological changes, virus distributions, immunologic properties and multi-omic features caused by SARS-CoV-2 in the explanted lungs from the world's first successful lung transplantation of a COVID-19 patient. MATERIALS AND METHODS:A total of 36 samples were collected from the lung...

journal_title：European journal of clinical investigation

authors： Chen XJ,Li K,Xu L,Yu YJ,Wu B,He YL,Zhao WE,Li D,Luan CX,Hu L,Wang J,Ding JJ,Yu YF,Li JX,Tan ZM,Liu XF,Wei D,Zhang ZH,Guo XJ,Su C,Hu ZB,Guo YS,Chen JY,Chen F

更新日期：2021-01-01 00:00:00

abstract：:The collagenolytic activities were assayed in fibroblast cultures established from ten keratoconus and six control corneal explants. The assays included those for both type I and type IV collagenase. The amount of free, directly assayable type I collagenase was highly increased in the media of keratoconus primary cell...

journal_title：European journal of clinical investigation

authors： Ihalainen A,Salo T,Forsius H,Peltonen L

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Microcirculatory changes contribute to clinical symptoms and disease progression in chronic heart failure (CHF). A depression of coronary flow reserve is associated with a lower myocardial capillary density in biopsies. We hypothesized that changes in cardiac microcirculation might also be refl...

journal_title：European journal of clinical investigation

authors： Wadowski PP,Hülsmann M,Schörgenhofer C,Lang IM,Wurm R,Gremmel T,Koppensteiner R,Steinlechner B,Schwameis M,Jilma B

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Increased intestinal permeability in cirrhosis exerts a pivotal role in the pathogenesis of spontaneous bacterial peritonitis and other complications of cirrhosis through promotion of systemic endotoxemia. This study was designed to investigate whether the expression of tight junction (TJ) proteins, which re...

journal_title：European journal of clinical investigation

authors： Assimakopoulos SF,Tsamandas AC,Tsiaoussis GI,Karatza E,Triantos C,Vagianos CE,Spiliopoulou I,Kaltezioti V,Charonis A,Nikolopoulou VN,Scopa CD,Thomopoulos KC

更新日期：2012-04-01 00:00:00

abstract：:Fibromuscular dysplasia (FMD) is an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries, mostly involving renal and cervical arteries. As a result of better and more systematic screening, it appears that in...

journal_title：European journal of clinical investigation

authors： Van der Niepen P,van Tussenbroek F,Devos H,Debing E,Di Monaco S,Goffette P,Astarci P,Persu A

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Experimental evidence indicates that statins might have direct vascular effects independently from low-density lipoprotein (LDL) cholesterol reduction and we reported that the reduction in urinary albumin excretion rate during Simvastatin treatment in type 2 diabetic patients was not correlated with LDL-chol...

journal_title：European journal of clinical investigation

authors： Tonolo G,Melis MG,Formato M,Angius MF,Carboni A,Brizzi P,Ciccarese M,Cherchi GM,Maioli M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:RNA interference (RNAi) has become the method of choice for researchers wishing to target specific genes for silencing and has provided immense potential as therapeutic tools. This narrative review article aimed to understand potential benefits and limitations of RNAi technique for clinical application and i...

journal_title：European journal of clinical investigation

authors： Chen SH,Zhaori G

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Parental history of type 2 diabetes (T2D) is associated with cardiometabolic risk. We aimed to investigate the associations of parental history of T2D with cardiometabolic biomarkers and to subsequently investigate to what extent these putative associations were explained by modifiable factors. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Abbasi A,Corpeleijn E,van der Schouw YT,Stolk RP,Spijkerman A,van der A DL,Navis G,Bakker SJ,Beulens JW

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:After the Q fever outbreak in the Netherlands between 2007 and 2010, more than 300 patients with chronic Q fever have been identified. Some patients were also diagnosed with systemic sclerosis, a rare immune-mediated disease. We aimed to increase awareness of concomitant chronic Q fever infection and systemi...

journal_title：European journal of clinical investigation

authors： Jansen AFM,Raijmakers RPH,van Deuren M,Vonk MC,Bleeker-Rovers CP

更新日期：2019-07-01 00:00:00

abstract：:Urine was collected in four healthy infants, born after 35-39 weeks of gestation. The collections were made for 24 h starting immediately after birth. Bile acids were extracted, separated into conjugate groups, solvolysed, hydrolysed and quantified by gas-liquid chromatography as methyl ester trimethylsilyl ether deri...

journal_title：European journal of clinical investigation

authors： Strandvik B,Wikström SA

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:A hyaluronan-loading test has been developed for assessment of hyaluronan kinetics and applied in patients with liver and joint diseases. This test describes the metabolic process of hyaluronan but cannot define the specific contribution of different organs. A method for labelling of hyaluronan with the shor...

journal_title：European journal of clinical investigation

authors： Lindqvist U,Westerberg G,Bergström M,Torsteindottir I,Gustafson S,Sundin A,Lööf L,Långström B

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Based on a report of a marked increase in the erythropoietin concentration ([EPO]) a few hours after the cessation of a single 2-h session of O(2) breathing, short periods of O(2) administration have been advocated as a therapy for anaemia. Accordingly, the purpose of the present study was to evaluate this t...

journal_title：European journal of clinical investigation

authors： Keramidas ME,Norman B,Gustafsson T,Eiken O,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have suggested that inhibitors of the renin angiotensin system (RAS) might be useful to slow the progression of valvular calcification in patients with aortic stenosis (AS). OBJECTIVES:The aim of this study was to evaluate the relationships between the weight and tissue rem...

journal_title：European journal of clinical investigation

authors： Côté N,Couture C,Pibarot P,Després JP,Mathieu P

更新日期：2011-11-01 00:00:00

abstract：:Basal cyclic AMP levels in blood mononuclear cells from healthy human donors has been studied. A great variation in cyclic AMP content ranging from below 2 to 20 pmol 10(-6) cells was seen. Incubation of the cells at 37 degrees C mostly showed a time-dependent decrease in basal cyclic AMP, levelling off after 16 h. Wh...

journal_title：European journal of clinical investigation

authors： Svenson M,Permin H,Wiik A

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Thymosin β4 (Tβ4) was recently found at high concentration in the bronchoalveolar lavage fluid (BALF) of scleroderma patients with lung involvement. It has been hypothesized that Tβ4 may exert a cyto-protective effect during lung injury because lower Tβ4 levels were associated with interstitial lung disease ...

journal_title：European journal of clinical investigation

authors： Conte E,Genovese T,Gili E,Esposito E,Iemmolo M,Fruciano M,Fagone E,Pistorio MP,Crimi N,Cuzzocrea S,Vancheri C

更新日期：2013-03-01 00:00:00

abstract：:Testosterone levels are decreased in obese men but increased in obese women. The interplay between gonadal steroids and leptin is, at present, far from being elucidated. This study was carried out to investigate the relationship between serum leptin, plasma insulin, insulin sensitivity and free testosterone in 46 men ...

journal_title：European journal of clinical investigation

authors： Vettor R,De Pergola G,Pagano C,Englaro P,Laudadio E,Giorgino F,Blum WF,Giorgino R,Federspil G

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:We investigated whether plasma ferritin levels through the pro-inflammatory effects of free iron are associated with adipose tissue dysfunction in a relevant population of patients with manifest vascular disease who would potentially benefit the most from further aetiological insights. MATERIALS AND METHODS...

journal_title：European journal of clinical investigation

authors： Westerink J,Olijhoek JK,Koppen A,Faber DR,Kalkhoven E,Monajemi H,van Asbeck BS,van der Graaf Y,Visseren FL

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Several studies have reported a significant gender difference in low-density lipoprotein (LDL) size, with men being characterized by smaller, denser LDL particles than women, and it has been suggested that the contribution of the greater accumulation of visceral adipose tissue in men compared with women may ...

journal_title：European journal of clinical investigation

authors： Lemieux I,Pascot A,Lamarche B,Prud'homme D,Nadeau A,Bergeron J,Després JP

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Amadori-albumin, a major glycated protein, is involved in experimental hyperglycaemia-induced microvascular complications, and is associated with advanced nephropathy in Type I diabetic patients in humans. Our aim was to assess the association of Amadori-albumin with early nephropathy and with retinopathy in...

journal_title：European journal of clinical investigation

authors： Schalkwijk CG,Chaturvedi N,Twaafhoven H,van Hinsbergh VW,Stehouwer CD,EUCLID Study Group.

更新日期：2002-07-01 00:00:00

abstract：:N-3 fatty acids were supplied to a 36-year-old female patient suffering from ulcerative colitis and severe steroid side-effects, in a sequence of parenteral and enteral administration. During a moderately active period of disease, 200 ml d-1 fish oil-derived lipid emulsion (eicosapentaenoic acid [EPA], 4.2 g; docosahe...

journal_title：European journal of clinical investigation

authors： Grimminger F,Führer D,Papavassilis C,Schlotzer E,Mayer K,Heuer KU,Kiss L,Walmrath D,Piberhofer S,Lübbecke F

更新日期：1993-11-01 00:00:00