The effects of administrations of HCl, NH4Cl and NH4HCO3 on the excretion of urea and ammonium in man.

abstract：:The fate of noradrenaline released from sympathetic endings differs from that of noradrenaline secreted directly into the bloodstream. This has been used to establish a single sample test for the exclusion of phaeochromocytoma in patients with borderline elevation of plasma noradrenaline concentration. This test is ba...

journal_title：European journal of clinical investigation

authors： Brown MJ

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Burnout represents a syndrome that is related to demanding job characteristics combined with the absence of resources or motivational job characteristics. The aim of this position study was to present strategies that individuals use to minimize burnout and its unfavourable effects. MATERIALS AND METHODS:The...

journal_title：European journal of clinical investigation

authors： Demerouti E

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:It is well known that space travel cause post-flight orthostatic hypotension and it was assumed that autonomic cardiovascular control deteriorates in space. Lower body negative pressure (LBNP) was used to assess autonomic function of the cardiovascular system. METHODS:LBNP tests were performed on six crew-m...

journal_title：European journal of clinical investigation

authors： Baisch F,Beck L,Blomqvist G,Wolfram G,Drescher J,Rome JL,Drummer C

更新日期：2000-12-01 00:00:00

abstract：:The effects of percutaneous electrical stimulation (70 V, 300 microseconds pulses at 30 Hz) on muscle composition and rate of protein synthesis were studied in seven patients with quadriceps atrophy secondary to unilateral osteoarthritis of the knee (stimulated group). Quadriceps were stimulated on the affected side f...

journal_title：European journal of clinical investigation

authors： Gibson JN,Morrison WL,Scrimgeour CM,Smith K,Stoward PJ,Rennie MJ

更新日期：1989-04-01 00:00:00

abstract：:In contrast to bile salts, which undergo a highly efficient enterohepatic circulation with multiple regulatory and physiologic functions, glucuronic acid conjugates of bilirubin are biliary excretory molecules that in health do not have a continuing biologic life. Intestinal absorptive cells are devoid of recapture tr...

journal_title：European journal of clinical investigation

authors： Vítek L,Carey MC

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Cholecystolithiasis is a highly prevalent condition in the Western world. Gallbladder stone-related conditions represent the second most common gastrointestinal pathology. Cholesterol stones represent over 80% of gallstones. Cholesterol stones develop secondary to crystallization of bile cholesterol. Water r...

journal_title：European journal of clinical investigation

authors： Ambe PC,Gödde D,Zirngibl H,Störkel S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:To investigate the clinical features of thyroid cancer in aging patients and to present the results of treatment. From this we can provide bases for earlier diagnoses and better treatment of thyroid malignancies in older patients. MATERIALS AND METHODS:In this study a retrospective analysis was performed wi...

journal_title：European journal of clinical investigation

authors： Lin JD,Chao TC,Chen ST,Weng HF,Lin KD

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Acute hyperglycaemia is known to inhibit jejunal interdigestive motility. This study was undertaken to establish the effects of hyperglycaemia on fed jejunal motility and small intestinal transit time, and to establish if the effects of hyperglycaemia are mediated in part by hyperinsulinaemia. METHODS:Nine ...

journal_title：European journal of clinical investigation

authors： Byrne MM,Pluntke K,Wank U,Schirra J,Arnold R,Göke B,Katschinski M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:During exposure to high altitude, the immune system is altered. During hypoxia, an increase in interleukin (IL)-6 and high sensitivity C-reactive protein (hs-CRP), and an increase in natural killer cells and decrease in T cells in blood was shown. However, the impact of hypoxia on dendritic cells has not bee...

journal_title：European journal of clinical investigation

authors： Yilmaz A,Ratka J,Rohm I,Pistulli R,Goebel B,Asadi Y,Petri A,Kiehntopf M,Figulla HR,Jung C

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Experimental evidence indicates that statins might have direct vascular effects independently from low-density lipoprotein (LDL) cholesterol reduction and we reported that the reduction in urinary albumin excretion rate during Simvastatin treatment in type 2 diabetic patients was not correlated with LDL-chol...

journal_title：European journal of clinical investigation

authors： Tonolo G,Melis MG,Formato M,Angius MF,Carboni A,Brizzi P,Ciccarese M,Cherchi GM,Maioli M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Several clinical trials have suggested that a metabolic cocktail of glucose-insulin-potassium (GIK) decreases mortality rates in patients with acute myocardial infarction (AMI). It has also been reported that Fas-mediated apoptosis plays an important role in ischaemic/reperfusion injury in the rat model. Thi...

journal_title：European journal of clinical investigation

authors： Zhang L,Zhang L,Li YH,Zhang HY,Chen ML,Gao MM,Hu AH,Yang HS,Yang HS

更新日期：2005-03-01 00:00:00

abstract：:The aim of this study was to investigate the involvement of the monocyte-derived cytokines interleukin 1beta (IL-1beta), interleukin 6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) in idiopathic inflammatory bowel disease. Endoscopic biopsies of normal and inflamed intestinal mucosa were obtained from patients w...

journal_title：European journal of clinical investigation

authors： Grottrup-Wolfers E,Moeller J,Karbach U,Muller-Lissner S,Endres S

更新日期：1996-02-01 00:00:00

abstract：:Pancreatic polypeptide was infused intravenously in healthy fasting subjects at 1 pmol kg-1 (n = 7) and 4 pmol kg-1 min-1 (n = 10) producing plasma PP concentrations of 223 +/- 37 pmol/l (mean +/- SEM) and 891 +/- 64 pmol/l respectively. These levels are similar to and four-fold higher than those seen after a normal m...

journal_title：European journal of clinical investigation

authors： Adrian TE,Greenberg GR,Barnes AJ,Christofides ND,Alberti KG,Bloom SR

更新日期：1980-06-01 00:00:00

abstract：:The effects of treating the anaemia of end-stage renal failure with erythropoietin were studied in nine dialysis patients. The increase in haemoglobin concentration (by 59% from 7.0 +/- 1.2 to 11.1 +/- 1.1 g dl-1) was associated with increases in exercise duration (by 41%) and maximum oxygen consumption (by 34%). Trea...

journal_title：European journal of clinical investigation

authors： Lewis NP,Macdougall IC,Willis N,Coles GA,Williams JD,Henderson AH

更新日期：1993-07-01 00:00:00

abstract：:Patients with primary biliary cirrhosis (PBC) are usually characterized by the presence of antibody to pyruvate dehydrogenase complex (PDC) in the sera and PDC-specific T cells in the liver. However, most of the patients with PBC do not show peripheral blood T cells response to PDC. In this study, we re-evaluated the ...

journal_title：European journal of clinical investigation

authors： Akbar SM,Yamamoto K,Miyakawa H,Ninomiya T,Abe M,Hiasa Y,Masumoto T,Horiike N,Onji M

更新日期：2001-07-01 00:00:00

abstract：:Bradykinin infusion has been shown to improve glucose metabolism in non-insulin-dependent diabetic subjects (NIDD). Therefore, we tested the following hypothesis: inhibition of Kininase II, the bradykinin (BK) degrading enzyme, by captopril may also improve glucose metabolism in NIDD. Immediate effects of captopril on...

journal_title：European journal of clinical investigation

authors： Jauch KW,Hartl W,Guenther B,Wicklmayr M,Rett K,Dietze G

更新日期：1987-10-01 00:00:00

abstract：:Infusion of ethanol (0.6 g/kg body wt) caused marked hypoglycaemia in subjects fasted for 36 h. Previous administration of the alcohol dehydrogenase (ADH) inhibitor 4-methylpyrazole (4-MP, 7 mg/kg body wt i.v.) strongly suppressed the ethanol-induced hypoglycaemia. The rate of ethanol elimination was 84.6 mg/kg per ho...

journal_title：European journal of clinical investigation

authors： Salaspuro MP,Pikkarainen P,Lindros K

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Foetal growth monitoring is an essential component of prenatal care with postnatal impact. The aim of the study was to construct reference ranges for foetal biometric parameters in Greek foetuses and to compare them with previously published models. MATERIALS AND METHODS:Measurements from 1200 Greek foetuse...

journal_title：European journal of clinical investigation

authors： Sotiriadis A,Eleftheriades M,Chatzinikolaou F,Hassiakos D,Chrousos GP,Pervanidou P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:A more complete assessment of coronary artery disease (CAD) can be performed by coronary computed tomography angiography (CCTA). The aim was to assess the prevalence, distribution and characteristics of coronary artery disease (CAD) and the reclassification of cardiovascular risk by CCTA in an asymptomatic S...

journal_title：European journal of clinical investigation

authors： García-Ortiz L,Barreiro-Perez M,Merchan-Gómez S,Ignacio Recio-Rodriguez J,Sánchez-Aguadero N,Alonso-Dominguez R,Lugones-Sanchez C,Rodríguez-Sanchez E,Sanchez PL,Gómez-Marcos MA,on behalf EVA investigators.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:We have investigated the potential for using antisense technology as a means of delivering treatment for acute myeloblastic leukaemia (FAB-M2) by gene therapy. MATERIALS AND METHODS:A test recombinant adenovirus vector was constructed containing human c-myc antisense fragments to study the effects of alteri...

journal_title：European journal of clinical investigation

authors： Chen JP,Chen L,Leek J,Lin C

更新日期：2006-01-01 00:00:00

abstract：:In this study the muscarinic receptor antagonist atropine and the cholecystokinin (CCK)-A receptor antagonist loxiglumide were used to investigate the relative importance of cholinergic and CCK-mediated regulation of intestinal phase antro-pyloro-duodenal motility. Plasma levels of gastrointestinal hormones [pancreati...

journal_title：European journal of clinical investigation

authors： Katschinski M,Schirra J,Begliner C,Langbein S,Wank U,D'Amato M,Arnold R

更新日期：1996-07-01 00:00:00

abstract：:The stimulant action of branched-chain amino acids upon insulin release was examined in rat pancreatic islets incubated at physiological concentrations of D-glucose and L-glutamine. In the presence of the latter nutrients, L-leucine and L-isoleucine used together at a physiological concentration (0.25 mmol/l each) dou...

journal_title：European journal of clinical investigation

authors： Sener A,Malaisse WJ

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Profilin-1 is a ubiquitous, actin-binding protein that plays an important role in the regulation of actin polymerization and cytoskeleton remodelling and contributes to vascular dysfunction. We conducted this study to investigate the association of serum profilin-1 levels with fatal and nonfatal CVE in a coh...

journal_title：European journal of clinical investigation

authors： Eroglu E,Unal HU,Guclu A,Kocyigit I,Karaman M,Saglam M,Gezer M,Tas A,Zararsiz G,Eyileten T,Aydin İ,Oguz Y,Gungor O,Yilmaz MI

更新日期：2017-12-01 00:00:00

abstract：:To examine the possible effects of hyperoxalaemia on anaerobic metabolism and erythrocyte pyruvate kinase activity, we induced a rise in plasma oxalate in 11 dialysis patients by the oral administration of ascorbic acid, 500 mg day-1 for 3 weeks. Blood samples were taken from the same antecubital vein before and after...

journal_title：European journal of clinical investigation

authors： Tomson CR,Channon SM,Ward MK,Laker MF

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:The role of the pattern, quantity and site of insulin secretion in the tolerance to a glucose challenge is not fully evaluated in humans because it is difficult to obtain appropriate clinical models. DESIGN:To address this issue, we studied subjects with reduced pancreatic mass (hemipancreatectomized, HEMI)...

journal_title：European journal of clinical investigation

authors： Battezzati A,Zerbi A,Perseghin G,Caumo A,Terruzzi I,Di Carlo V,Luzi L

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Polymorphonuclear leucocytes (PMNLs) play a key role in the nonspecific immune defence. Cinacalcet reduces serum calcium levels in kidney transplant recipients with mineral bone disorder associated with chronic kidney disease. We investigated essential functions of PMNLs of kidney transplant recipients with ...

journal_title：European journal of clinical investigation

authors： Cohen G,Raupachova J,Borchhardt K,Hörl WH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Soluble TWEAK (sTWEAK) and asymmetric dimethyl arginine (ADMA) concentrations have been associated with endothelial function in patients with chronic kidney disease (CKD). We tested the hypothesis that the improvement in endothelial function observed after renal transplantation is directly linked to the norm...

journal_title：European journal of clinical investigation

authors： Yilmaz MI,Sonmez A,Saglam M,Yaman H,Unal HU,Gok M,Cetinkaya H,Eyileten T,Oguz Y,Sari S,Yildirim AO,Vural A,Carrero JJ,Blanco-Colio LM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Plasmacytoid dendritic cells (pDCs) are multifunctional bone-marrow-derived immune cells that are key players in bridging the innate and adaptive immune systems. Activation of pDCs through toll-like receptor agonists has proven to be an effective treatment for some neoplastic disorders. MATERIALS AND METHOD...

journal_title：European journal of clinical investigation

authors： Lombardi VC,Khaiboullina SF,Rizvanov AA

更新日期：2015-01-01 00:00:00

abstract：:A kindred in which several members have otherwise typical acute intermittent porphyria but normal erythrocyte uroporphyrinogen-I-synthase activity has been described from Finland. We studied two porphyric members of this kindred, two patients with typical acute intermittent porphyria, and two healthy controls using th...

journal_title：European journal of clinical investigation

authors： Mustajoki P,Tenhunen R

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVE:obesity-related microvascular dysfunction, including alterations in rhythmic changes in vascular diameter, so-called 'vasomotion', may be important in the clustering of obesity with other cardiovascular risk factors. Adipokines have been suggested to play a role in obesity-related vascular dysfunction. Altera...

journal_title：European journal of clinical investigation

authors： de Boer MP,Wijnstok NJ,Serné EH,Eringa EC,Stehouwer CD,Flyvbjerg A,Hoekstra T,Heymans MW,Meijer RI,Twisk JW,Smulders YM

更新日期：2014-07-01 00:00:00