Lipoprotein(a), type 2 diabetes and vascular risk in coronary patients.

abstract：:Combined 47Calcium kinetic and calcium balance studies with correction for dermal calcium loss were performed in thirteen patients with primary hyperparathyroidism (PHP), in whom serum bone-Gla-protein (S-BGP) was measured, and in ten matched controls. Dietary calcium was normal in PHP but both net (7.9 +/- 1.4 mmol C...

journal_title：European journal of clinical investigation

authors： Charles P,Mosekilde L,Jensen FT

更新日期：1986-08-01 00:00:00

abstract：:There is considerable information to indicate that when there is vessel injury, platelets can play a major role in the development of atherosclerosis and its thromboembolic complications in the non-diabetic population. Diabetes is a disease associated with an increased risk of vascular complications, but the nature of...

journal_title：European journal of clinical investigation

authors： Winocour PD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Soluble TWEAK (sTWEAK) and asymmetric dimethyl arginine (ADMA) concentrations have been associated with endothelial function in patients with chronic kidney disease (CKD). We tested the hypothesis that the improvement in endothelial function observed after renal transplantation is directly linked to the norm...

journal_title：European journal of clinical investigation

authors： Yilmaz MI,Sonmez A,Saglam M,Yaman H,Unal HU,Gok M,Cetinkaya H,Eyileten T,Oguz Y,Sari S,Yildirim AO,Vural A,Carrero JJ,Blanco-Colio LM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Thymosin β4 (Tβ4) was recently found at high concentration in the bronchoalveolar lavage fluid (BALF) of scleroderma patients with lung involvement. It has been hypothesized that Tβ4 may exert a cyto-protective effect during lung injury because lower Tβ4 levels were associated with interstitial lung disease ...

journal_title：European journal of clinical investigation

authors： Conte E,Genovese T,Gili E,Esposito E,Iemmolo M,Fruciano M,Fagone E,Pistorio MP,Crimi N,Cuzzocrea S,Vancheri C

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Platelets are involved in the pathogenesis of bronchial asthma, including aspirin-sensitive asthma (ASA). The pineal hormone melatonin (MT) has been described as inhibiting several physiological processes in platelets. The MT metabolite - N-acetyl-5-methoxy-kynurenamine - has a chemical structure similar to ...

journal_title：European journal of clinical investigation

authors： Evsyukova HV

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The pathogenesis of atherosclerosis and acute coronary syndromes involves inflammation and immunological mechanisms. We hypothesized that patients with unstable angina may have an imbalance between inflammatory and anti-inflammatory cytokines. DESIGN:Plasma levels of tumour necrosis factor (TNF)alpha and in...

journal_title：European journal of clinical investigation

authors： Waehre T,Halvorsen B,Damås JK,Yndestad A,Brosstad F,Gullestad L,Kjekshus J,Frøland SS,Aukrust P

更新日期：2002-11-01 00:00:00

abstract：:As in women receiving oestrogens the administration of 17beta-oestradiol to ovariectomized female rats caused a rise in fasting plasma triglycerides and a fall in plasma glucose. Progesterone, on the other hand, had no significant effects. In the oestradiol treated rats, the portal vein basal insulin levels were sligh...

journal_title：European journal of clinical investigation

authors： Mandour T,Kissebah AH,Wynn V

更新日期：1977-06-01 00:00:00

abstract：:We measured plasma sulphur amino acids in twenty-two patients with chronic renal failure and compared the findings with those obtained in twenty-two normal subjects. In fasting blood (08.00 hours) cysteine-homocysteine mixed disulphide was significantly increased in the renal patients, mean values (+/- SD) being 8.2 +...

journal_title：European journal of clinical investigation

authors： Wilcken DE,Gupta VJ

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Although both strength training (ST) and endurance training (ET) seem to be beneficial in type 2 diabetes mellitus (T2D), little is known about post-exercise glucose profiles. The objective of the study was to report changes in blood glucose (BG) values after a 4-month ET and ST programme now that a device f...

journal_title：European journal of clinical investigation

authors： Cauza E,Hanusch-Enserer U,Strasser B,Kostner K,Dunky A,Haber P

更新日期：2005-12-01 00:00:00

abstract：:The influence of insulin on lipolysis and glucose metabolism in abdominal adipose tissue was studied in situ with the microdialysis technique during a euglycaemic insulin clamp (1 mU kg-1 min-1) in nine cirrhotic patients and 10 controls. The cirrhotic patients displayed a 50% decrease in glucose utilization rate duri...

journal_title：European journal of clinical investigation

authors： Johansson U,Arner P,Bolinder J,Hagström-Toft E,Ungerstedt U,Eriksson LS

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:In obese subjects, chronic low-grade inflammation contributes to an increased risk of metabolic abnormalities, which are reversed by weight loss. Sustained weight loss, however, is difficult to achieve and more insight into dietary approaches on anti-inflammatory responses in obese subjects is needed. In thi...

journal_title：European journal of clinical investigation

authors： Jellema A,Plat J,Mensink RP

更新日期：2004-11-01 00:00:00

abstract：:Alpha-naphthyl-isothiocyanate (ANIT)-induced intrahepatic cholangitis was associated with significant polyuria in rats. The urine output in the experimental rats was about two and a half to four fold higher than that in the controls. The polyuria was accompanied by polydypsia and disappeared when water intake was limi...

journal_title：European journal of clinical investigation

authors： Tur-Kaspa R,Adler R,Popovtzer MM,Eliakim M

更新日期：1983-02-01 00:00:00

abstract：AIM:Observationally, low serum testosterone among men is associated with cardiovascular diseases and its risk factors, but it is unclear whether raising endogenous androgens would be protective. To clarify the role of androgens, the association of two different androgen biomarkers (serum testosterone and androstanediol...

journal_title：European journal of clinical investigation

authors： Schooling CM

更新日期：2013-12-01 00:00:00

abstract：:The studies were designed to explore the effect of the converting enzyme inhibitor captopril on the activity of the sympathetic nervous system during basal conditions and following graded physical exercise in patients with essential hypertension. Seven males and two females, aged 36-59 years, were hospitalized under m...

journal_title：European journal of clinical investigation

authors： Manhem P,Bramnert M,Hulthén UL,Hökfelt B

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:After the Q fever outbreak in the Netherlands between 2007 and 2010, more than 300 patients with chronic Q fever have been identified. Some patients were also diagnosed with systemic sclerosis, a rare immune-mediated disease. We aimed to increase awareness of concomitant chronic Q fever infection and systemi...

journal_title：European journal of clinical investigation

authors： Jansen AFM,Raijmakers RPH,van Deuren M,Vonk MC,Bleeker-Rovers CP

更新日期：2019-07-01 00:00:00

abstract：:The present study investigated how a cholinergic agonist modifies interdigestive motility and secretion of the upper gastrointestinal tract and how muscarinic and cholecystokinin receptor blockade interfere with this direct cholinergic stimulation. In eight healthy volunteers, gastrointestinal motor and secretory resp...

journal_title：European journal of clinical investigation

authors： Katschinski M,Steinicke C,Reinshagen M,Dahmen G,Beglinger C,Arnold R,Adler G

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) histology/immunohistochemistry, KIT D816V mutation analysis and serum tryptase measurements are mandatory tools for diagnosis of systemic mastocytosis (SM). MATERIALS AND METHODS:Within the 'German Registry of Disorders on Eosinophils and Mast Cells', we identified 65 patients with SM who h...

journal_title：European journal of clinical investigation

authors： Jawhar M,Schwaab J,Horny HP,Sotlar K,Naumann N,Fabarius A,Valent P,Cross NC,Hofmann WK,Metzgeroth G,Reiter A

更新日期：2016-05-01 00:00:00

abstract：:• The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and public health practice. • The number of studies assessing the predictive ability is steadily increasing, but they vary widely in completeness of reporting...

journal_title：European journal of clinical investigation

authors： Janssens AC,Ioannidis JP,Bedrosian S,Boffetta P,Dolan SM,Dowling N,Fortier I,Freedman AN,Grimshaw JM,Gulcher J,Gwinn M,Hlatky MA,Janes H,Kraft P,Melillo S,O'Donnell CJ,Pencina MJ,Ransohoff D,Schully SD,Seminara D,

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Minimal lipoprotein(a) [Lp(a)] target values are advocated for high-risk cardiovascular patients. We investigated the prognostic value of Lp(a) in the acute setting of patients with acute coronary syndromes (ACS). MATERIALS AND METHODS:Plasma levels of Lp(a) were collected at time of angiography from 1711 p...

journal_title：European journal of clinical investigation

authors： Gencer B,Rigamonti F,Nanchen D,Vuilleumier N,Kern I,Aghlmandi S,Klingenberg R,Räber L,Auer R,Carballo D,Carballo S,Heg D,Windecker S,Lüscher TF,Matter CM,Rodondi N,Mach F

更新日期：2019-07-01 00:00:00

abstract：:Skeletal muscle glycogen deposition, and the activation of muscle glycogen synthase and pyruvate dehydrogenase during a hyerinsulinaemic euglycaemic clamp have been measured in six young and six elderly males matched for body mass index, physical activity and diet. Clamp glucose requirement (insulin, 0.1 U kg-1 h-1) w...

journal_title：European journal of clinical investigation

authors： Kruszynska YT,Petranyi G,Alberti KG

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Thiopurines (TP) are widely used in the management of inflammatory bowel diseases. Side effects and inefficacy are a major concern as they lead to withdrawal of the drug. MATERIALS AND METHODS:Tools investigating TP metabolism are useful to avoid inadequate cessation of TP therapy. RESULTS:TP metabolism is...

journal_title：European journal of clinical investigation

authors： Dewit O,Starkel P,Roblin X

更新日期：2010-11-01 00:00:00

abstract：:Insulin resistance has been reported in normal ageing but discrepancies between such studies may be related to compounding factors such as body composition and exercise patterns. We employed a two-step hyperinsulinaemic euglycaemic clamp to assess peripheral and hepatic tissue insulin sensitivity and glucose recycling...

journal_title：European journal of clinical investigation

authors： Broughton DL,James OW,Alberti KG,Taylor R

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) represents the most relevant cause of death and morbidity in the adult population of developed and developing countries. During the last decades, a strong research effort has been performed to identify more selective markers and better assess the cardiovascular risk in both prim...

journal_title：European journal of clinical investigation

authors： Quercioli A,Montecucco F,Bertolotto M,Ottonello L,Pende A,Mach F,Dallegri F

更新日期：2010-07-01 00:00:00

abstract：:Transfusion-related morbidity is an emerging challenge in chronically transfused patients with low-risk myelodysplastic syndromes (MDS). In these patients, transfusion-induced iron overload may represent a leading medical problem. However, although iron-chelating drugs are available, little is known about optimal diag...

journal_title：European journal of clinical investigation

authors： Valent P,Krieger O,Stauder R,Wimazal F,Nösslinger T,Sperr WR,Sill H,Bettelheim P,Pfeilstöcker M

更新日期：2008-03-01 00:00:00

abstract：:The work was designed to study the effects of a meat meal on glomerular filtration rate (GFR), renal plasma flow (RPF), and plasma concentrations of glucagon, insulin, growth hormone, renin, aldosterone, total amino acids, and NH3 in healthy humans (H) as well as in patients with Child A liver cirrhosis (LC). The meat...

journal_title：European journal of clinical investigation

authors： De Santo NG,Anastasio P,Loguercio C,del Vecchio Blanco C,Capasso G,Coppola S,Bellini L,Spagnuolo G,Federico P,Alfieri R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Antiphospholipid syndrome (APS) is a systemic autoimmune vascular disease characterized by recurrent thrombotic episodes and/or obstetric complications. Management of this disease has been restricted mainly to anticoagulation; however, in recent years, significant advancement has been made in elucidating the...

journal_title：European journal of clinical investigation

authors： Mehdi AA,Uthman I,Khamashta M

更新日期：2010-05-01 00:00:00

abstract：:In controls and in patients suffering from congestive heart failure (CHF) the circulating levels of catecholamines, neuropeptide Y-like immunoreactivity (NPY-LI), vasoactive intestinal peptide-LI (VIP-LI), substance P-LI (SP-LI) and calcitonin generated peptide-LI (CGRP-LI) markers of sympathetic, parasympathetic and ...

journal_title：European journal of clinical investigation

authors： Edvinsson L,Ekman R,Hedner P,Valdemarsson S

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Little is known about gallbladder motility in patients with black pigment stones when compared to cholesterol gallstone patients, or about their relationship to biliary composition, crystallization and stone characteristics. DESIGN:Fasting and postprandial gallbladder volumes were studied by ultrasonography...

journal_title：European journal of clinical investigation

authors： Portincasa P,Di Ciaula A,Vendemiale G,Palmieri V,Moschetta A,Vanberge-Henegouwen GP,Palasciano G

更新日期：2000-04-01 00:00:00

abstract：:The action of lecithin:cholesterol acyltransferase (LCAT) was studied on an abnormal lipoprotein (LP-X) rich in phosphatidylcholine and cholesterol from the plasma of patients with obstructive liver disease. 60 mg LP-X isolated free of other lipoproteins and subsequently labelled with 3H-cholesterol were incubated wit...

journal_title：European journal of clinical investigation

authors： Patsch JR,Soutar AK,Morrisett JD,Gotto AM Jr,Smith LC

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Linear growth restriction is a unique feature of paediatric inflammatory bowel diseases (IBD), and reduced insulin-like growth factor (IGF-1) is a major determinant of short stature. We aimed to assess factors influencing somatic height in children suffering from IBD. MATERIALS AND METHODS:This was a retros...

journal_title：European journal of clinical investigation

authors： Chouliaras G,Mantzou A,Margoni D,Tsilifis N,Pervanidou P,Panayotou I,Kanaka-Gantenbein C,Chrousos GP,Roma-Giannikou E

更新日期：2018-08-01 00:00:00