Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons.

abstract：:Rice yield have been affected by the increased extreme precipitation events in recent decades. Yet, the spatio-temporal patterns of extreme precipitation by rice type and phenology remain elusive. Here, we investigate the characteristics of four extreme precipitation indices across China's rice paddy and their potenti...

journal_title：Scientific reports

authors： Jian Y,Fu J,Li B,Zhou F

更新日期：2020-06-30 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Bebber DP,Butt N

更新日期：2018-10-01 00:00:00

abstract：:Identifying the occurrence mechanism of drug-induced side effects (SEs) is critical for design of drug target and new drug development. The expression of genes in biological processes is regulated by transcription factors(TFs) and/or microRNAs. Most of previous studies were focused on a single level of gene or gene se...

journal_title：Scientific reports

authors： Jia X,Jin Q,Liu X,Bian X,Wang Y,Liu L,Ma H,Tan F,Gu M,Chen X

更新日期：2017-07-20 00:00:00

abstract：:β-lactam antibiotics act as suicide substrates of transpeptidases responsible for the last cross-linking step of peptidoglycan synthesis in the bacterial cell wall. Nucleophilic attack of the β-lactam carbonyl by the catalytic residue (Ser or Cys) of transpeptidases results in the opening of the β-lactam ring and in t...

journal_title：Scientific reports

authors： Edoo Z,Arthur M,Hugonnet JE

更新日期：2017-08-22 00:00:00

abstract：:Chinese hamster ovary (CHO) cells are mainly used for recombinant protein production. However, the unstable transgene expression and lower transgene copy numbers are the major issues need to be resolved. Here, eleven internal ribosome entry site (IRES) elements from viral and cellular IRES were evaluated for foreign g...

journal_title：Scientific reports

authors： Chai YR,Ge MM,Wei TT,Jia YL,Guo X,Wang TY

更新日期：2018-04-27 00:00:00

abstract：:Early diagnosis of dementia including Alzheimer's disease (AD) is an urgent medical and welfare issue. However, to date, no simple biometrics have been available. We reported that blood DNA methylation levels of the COASY gene, which encodes coenzyme A synthase, were increased in individuals with AD and amnestic mild ...

journal_title：Scientific reports

authors： Kobayashi N,Shinagawa S,Niimura H,Kida H,Nagata T,Tagai K,Shimada K,Oka N,Shikimoto R,Noda Y,Nakajima S,Mimura M,Shigeta M,Kondo K

更新日期：2020-07-22 00:00:00

abstract：:Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offspring, resulting from suppression of intratesticular testosterone, and is used as a model for human testicular dysgenesis syndrome (TDS). DBP exposure in pregnancy induces focal dysgenetic areas in fetal testes that ap...

journal_title：Scientific reports

authors： Lara NLM,van den Driesche S,Macpherson S,França LR,Sharpe RM

更新日期：2017-05-31 00:00:00

abstract：:Understanding the response of the plant community to increasing nitrogen (N) deposition is helpful for improving pasture management in semi-arid areas. We implemented a 5-year N addition experiment in a Stipa krylovii steppe of Inner Mongolia, northern China. The aboveground biomass (AGB) and species richness were mea...

journal_title：Scientific reports

authors： He K,Qi Y,Huang Y,Chen H,Sheng Z,Xu X,Duan L

更新日期：2016-08-30 00:00:00

abstract：:Three kinds of Al-TiO2 samples and pure TiO2 samples were synthesized via a modified polyacrylamide gel route using different aluminum salts, including Al2(SO4)3∙18H2O, AlCl3, and Al(NO3)3∙9H2O under identical conditions. The influence of different aluminum salts on the phase purity, morphologies, thermal stability of...

journal_title：Scientific reports

authors： Luo JL,Wang SF,Liu W,Tian CX,Wu JW,Zu XT,Zhou WL,Yuan XD,Xiang X

更新日期：2017-08-14 00:00:00

abstract：:Medulloblastoma is a malignant pediatric tumor that arises from neural progenitors in the cerebellum. Despite a five-year survival rate of ~70%, nearly all patients incur adverse side effects from current treatment strategies that drastically impact quality of life. Roughly one-third of medulloblastoma are driven by a...

journal_title：Scientific reports

authors： Robinson MH,Maximov V,Lallani S,Farooq H,Taylor MD,Read RD,Kenney AM

更新日期：2019-09-20 00:00:00

abstract：:We present results from first-principles calculations on silane (SiH4) under pressure. We find that a three dimensional P-3 structure becomes the most stable phase above 241 GPa. A prominent structural feature, which separates the P-3 structure from previously observed/predicted SiH4 structures, is that a fraction of ...

journal_title：Scientific reports

authors： Cui W,Shi J,Liu H,Yao Y,Wang H,Iitaka T,Ma Y

更新日期：2015-08-12 00:00:00

abstract：:The synthesis of ordered monolayers of gold nano-urchin (Au-NU) nanostructures with controlled size, directly on thin films using a simple electrochemical method is reported in this study. In order to demonstrate one of the vast potential applications, the developed Au-NUs were formed on the electrodes of transducers ...

journal_title：Scientific reports

authors： Sabri YM,Kandjani AE,Ippolito SJ,Bhargava SK

更新日期：2016-04-19 00:00:00

abstract：:Staphylococcus lugdunensis is a commensal bacterium in humans and other animals that can cause serious infections. The aim of this research was to estimate the frequency of S. lugdunensis in pet cats and to characterize the S. lugdunensis isolates obtained. The prevalence of S. lugdunensis was 0.77% (4/523) in healthy...

journal_title：Scientific reports

authors： Bierowiec K

更新日期：2020-09-22 00:00:00

abstract：:The analysis of equine electrocardiographic (ECG) recordings is complicated by the absence of agreed abnormality classification criteria. We explore the applicability of several complexity analysis methods for characterization of non-linear aspects of electrocardiographic recordings. We here show that complexity estim...

journal_title：Scientific reports

authors： Alexeenko V,Fraser JA,Dolgoborodov A,Bowen M,Huang CL,Marr CM,Jeevaratnam K

更新日期：2019-02-22 00:00:00

abstract：:Herein, water-oxidation reaction by cobalt(II) phthalocyanine, N,N'-bis (salicylidene) ethylenediamino cobalt(II), nickel(II) Schiff base (N,N'-bis (salicylidene)ethylenediamino nickel(II), nickel(II)) phthalocyanine-tetrasulfonate tetrasodium, manganese(II) phthalocyanine, 5,10,15,20-Tetraphenyl-21H,23H-porphine mang...

journal_title：Scientific reports

authors： Najafpour MM,Feizi H

更新日期：2019-05-16 00:00:00

abstract：:Alp14 is a TOG-family microtubule polymerase from S. pombe that tracks plus ends and accelerates their growth. To interrogate its mechanism, we reconstituted dynamically unstable single isoform S. pombe microtubules with full length Alp14/TOG and Alp7, the TACC-family binding partner of Alp14. We find that Alp14 can d...

journal_title：Scientific reports

authors： Hussmann F,Drummond DR,Peet DR,Martin DS,Cross RA

更新日期：2016-02-11 00:00:00

abstract：:The expression of aminoglycoside-modifying enzymes represents a survival strategy of antibiotic-resistant bacteria. Aminoglycoside 2'-N-acetyltransferase [AAC(2')] neutralizes aminoglycoside drugs by acetylation of their 2' amino groups in an acetyl coenzyme A (CoA)-dependent manner. To understand the structural featu...

journal_title：Scientific reports

authors： Jeong CS,Hwang J,Do H,Cha SS,Oh TJ,Kim HJ,Park HH,Lee JH

更新日期：2020-12-09 00:00:00

abstract：:To increase the energy storage density of lithium-ion batteries, silicon anodes have been explored due to their high capacity. One of the main challenges for silicon anodes are large volume variations during the lithiation processes. Recently, several high-performance schemes have been demonstrated with increased life...

journal_title：Scientific reports

authors： Phadatare M,Patil R,Blomquist N,Forsberg S,Örtegren J,Hummelgård M,Meshram J,Hernández G,Brandell D,Leifer K,Sathyanath SKM,Olin H

更新日期：2019-10-10 00:00:00

abstract：:The role of changes in dopamine neuronal activity during the development of symptoms in affective disorders remains controversial. Here, we show that inactivation of NMDA receptors on dopaminergic neurons in adult mice led to the development of affective disorder-like symptoms. The loss of NMDA receptors altered activ...

journal_title：Scientific reports

authors： Jastrzębska K,Walczak M,Cieślak PE,Szumiec Ł,Turbasa M,Engblom D,Błasiak T,Parkitna JR

更新日期：2016-11-17 00:00:00

abstract：:Maternal obesity and overnutrition during pregnancy and lactation can program an increased risk of obesity in offspring. In this context, improving maternal metabolism may help reduce the intergenerational transmission of obesity. Here we show that, in Sprague-Dawley rats, selectively altering obese maternal gut micro...

journal_title：Scientific reports

authors： Paul HA,Bomhof MR,Vogel HJ,Reimer RA

更新日期：2016-02-12 00:00:00

abstract：:Miscanthus is a rhizomatous C4 grass which is considered as potential high-yielding energy crop with the low-nutrient requirements, high water-use efficiency, and capability of C mitigation. To better understand the genetic basis, an integrative analysis of the transcriptome and proteome was performed to identify impo...

journal_title：Scientific reports

authors： Sheng J,Zheng X,Wang J,Zeng X,Zhou F,Jin S,Hu Z,Diao Y

更新日期：2017-10-23 00:00:00

abstract：:Several systems can be represented as multiplex networks, i.e. in terms of a superposition of various graphs, each related to a different mode of connection between nodes. Hence, the definition of proper mathematical quantities aiming at capturing the added level of complexity of those systems is required. Various ste...

journal_title：Scientific reports

authors： Gemmetto V,Garlaschelli D

更新日期：2015-03-13 00:00:00

abstract：:Unpleasant emotional distraction can impair the retention of non-emotional information in working memory (WM). Research links the prefrontal cortex with the successful control of such biologically relevant distractors, although the temporal changes in this brain mechanism remain unexplored. We use magnetoencephalograp...

journal_title：Scientific reports

authors： García-Pacios J,Garcés P,Del Río D,Maestú F

更新日期：2015-06-12 00:00:00

abstract：:Gas-filled hollow-core fiber (HCF) pulse post-compressors generating few- to single-cycle pulses are a key enabling tool for attosecond science and ultrafast spectroscopy. Achieving optimum performance in this regime can be extremely challenging due to the ultra-broad bandwidth of the pulses and the need of an adequat...

journal_title：Scientific reports

authors： Conejero Jarque E,San Roman J,Silva F,Romero R,Holgado W,Gonzalez-Galicia MA,Alonso B,Sola IJ,Crespo H

更新日期：2018-02-02 00:00:00

abstract：:It is recently appreciated that many bacterial chemoreceptors have ligand-binding domains (LBD) of the dCACHE family, a structure with two PAS-like subdomains, one membrane-proximal and the other membrane-distal. Previous studies had implicated only the membrane-distal subdomain in ligand recognition. Here, we report ...

journal_title：Scientific reports

authors： Machuca MA,Johnson KS,Liu YC,Steer DL,Ottemann KM,Roujeinikova A

更新日期：2017-10-26 00:00:00

abstract：:Marine macroalgal forests are highly productive and iconic ecosystems, which are seriously threatened by number of factors such as habitat destruction, overgrazing, ocean warming, and pollution. The effect of chronic, but low levels of pollutants on the long-term survival of the canopy-forming algae is not well unders...

journal_title：Scientific reports

authors： de Caralt S,Verdura J,Vergés A,Ballesteros E,Cebrian E

更新日期：2020-10-20 00:00:00

abstract：:Alzheimer's disease (AD) is a lethal progressive neurological disorder affecting the memory. Recently, US Food and Drug Administration mitigated the standard for drug approval, allowing symptomatic drugs that only improve cognitive deficits to be allowed to accelerate on to clinical trials. Our study focuses on taurin...

journal_title：Scientific reports

authors： Kim HY,Kim HV,Yoon JH,Kang BR,Cho SM,Lee S,Kim JY,Kim JW,Cho Y,Woo J,Kim Y

更新日期：2014-12-12 00:00:00

abstract：:Multilevel severe compressive myelopathy is a challenging disorder for the surgeons, the aim of this study is to assess the efficacy and safety of a newly designed ultrasonic burr as an assistant tool to the ultrasonic scalpel in laminectomy for this disease. This is a retrospective comparative study, the included sub...

journal_title：Scientific reports

authors： Chen Y,Chang Z,Yu X,Song R,Huang W

更新日期：2018-03-05 00:00:00

abstract：:The high neutron detection efficiency, good gamma-ray discrimination and non-toxicity of 3He made of proportional counters filled with this gas the obvious choice for neutron detection, particularly in radiation portal monitors (RPM), used to control the illicit transport of nuclear material, of which neutron detector...

journal_title：Scientific reports

authors： Amaro FD,Monteiro CM,Dos Santos JM,Antognini A

更新日期：2017-02-09 00:00:00

abstract：:The overproduction of hydrogen peroxide is an inherent feature of some tumour cells and inflamed tissues. We took advantage of this peculiarity to eliminate cells using chemiluminescent peroxyoxalate reaction. We designed dispersions containing polyoxalate and tetramethylhematoporhyrin (TMHP) in dimethylphthalate drop...

journal_title：Scientific reports

authors： Romanyuk AV,Grozdova ID,Ezhov AA,Melik-Nubarov NS

更新日期：2017-06-13 00:00:00