A Canonical Biophysical Model of the CsrA Global Regulator Suggests Flexible Regulator-Target Interactions.

abstract：:High fat diet (HFD)-induced metabolic disorders may lead to emotional disorders. This study aimed to explore the effect of simvastatin (SMV) and bezafibrate (BZ) on improving HFD-induced emotional changes, and tried to identify their different mechanisms. The intraperitoneal glucose tolerance test (IPGTT) was used to ...

journal_title：Scientific reports

authors： Wang H,Zhou J,Liu QZ,Wang LL,Shang J

更新日期：2017-05-24 00:00:00

abstract：:Pseudomonas aeruginosa is a major threat for immune-compromised patients. Bacterial pneumonia can induce uncontrolled and massive neutrophil recruitment ultimately leading to acute respiratory distress syndrome and epithelium damage. Interleukin-22 plays a central role in the protection of the epithelium. In this stud...

journal_title：Scientific reports

authors： Broquet A,Jacqueline C,Davieau M,Besbes A,Roquilly A,Martin J,Caillon J,Dumoutier L,Renauld JC,Heslan M,Josien R,Asehnoune K

更新日期：2017-09-08 00:00:00

abstract：:Patient misidentification in imaging examinations has become a serious problem in clinical settings. Such misidentification could be prevented if patient characteristics such as sex, age, and body weight could be predicted based on an image of the patient, with an alert issued when a mismatch between the predicted and...

journal_title：Scientific reports

authors： Kawauchi K,Hirata K,Katoh C,Ichikawa S,Manabe O,Kobayashi K,Watanabe S,Furuya S,Shiga T

更新日期：2019-05-10 00:00:00

abstract：:By using silver nanoplatelets with a widely tunable localized surface plasmon resonance (LSPR), and their corresponding local field enhancement, here we show large manipulation of plasmonic enhanced upconversion in NaYF4:Yb(3+)/Er(3+) nanocrystals at the single particle level. In particular, we show that when the plas...

journal_title：Scientific reports

authors： Wang YL,Mohammadi Estakhri N,Johnson A,Li HY,Xu LX,Zhang Z,Alù A,Wang QQ,Shih CK

更新日期：2015-05-15 00:00:00

abstract：:Disturbances in calcium metabolism are common in individuals with chronic kidney disease (CKD), but whether they are associated with subsequent kidney function decline is less clear. In a CKD 3-5 cohort of 15,755 adult citizens of Stockholm with creatinine tests taken during 2006-2011 and concurrent calcium testing at...

journal_title：Scientific reports

authors： Janmaat CJ,van Diepen M,Gasparini A,Evans M,Qureshi AR,Ärnlöv J,Barany P,Elinder CG,Rotmans JI,Vervloet M,Dekker FW,Carrero JJ

更新日期：2018-03-26 00:00:00

abstract：:Temporal fluctuation of neural activity in the brain has an important function in optimal information processing. Spontaneous activity is a source of such fluctuation. The distribution of excitatory postsynaptic potentials (EPSPs) between cortical pyramidal neurons can follow a log-normal distribution. Recent studies ...

journal_title：Scientific reports

authors： Nobukawa S,Nishimura H,Yamanishi T

更新日期：2019-09-04 00:00:00

abstract：:A link between periodontitis and atherothrombosis has been highlighted. The aim of this study was to determine the influence of Porphyromonas gingivalis on endothelial microvesicles (EMVPg) shedding and their contribution to endothelial inflammation. Endothelial cells (EC) were infected with P. gingivalis (MOI = 100) ...

journal_title：Scientific reports

authors： Bugueno IM,Zobairi El-Ghazouani F,Batool F,El Itawi H,Anglès-Cano E,Benkirane-Jessel N,Toti F,Huck O

更新日期：2020-02-04 00:00:00

abstract：:Periconceptional supplementation with folic acid reduces the occurrence of neural tube defects (NTDs). The association between maternal abnormalities in homocysteine metabolism (e.g., hyperhomocysteinaemia, folate deficiency and low vitamin B12) and the risk of NTDs-affected pregnancies has been widely evaluated in re...

journal_title：Scientific reports

authors： Tang KF,Li YL,Wang HY

更新日期：2015-03-02 00:00:00

abstract：:Kaposiform hemangioendothelioma (KHE) is a relatively rare vascular tumor with an aggressive and infiltrating nature. Previous studies have revealed an exclusive relationship between KHE and Kasabach-Merritt Phenomenon (KMP), which is associated with high morbidity and mortality. No universally accepted treatment moda...

journal_title：Scientific reports

authors： Wu HW,Wang X,Zhang L,Zhao HG,Wang YA,Su LX,Fan XD,Zheng JW

更新日期：2016-10-31 00:00:00

abstract：:In this study, we report on a new approach for remote temperature probing that provides accuracy as good as 0.017°C (0.0055% accuracy) by measuring the magnetisation curve of magnetic nanoparticles. We included here the theoretical model construction and the inverse calculation method, and explored the impact caused b...

journal_title：Scientific reports

authors： Zhong J,Liu W,Kong L,Morais PC

更新日期：2014-10-15 00:00:00

abstract：:Insecticides and other agrochemicals have become indispensable components of the agricultural system to ensure a notable increase in crop yield and food production. As a natural consequence, chemical residues result in significantly increased contamination of both terrestrial and aquatic ecosystems. The present study ...

journal_title：Scientific reports

authors： Basal WT,Ahmed ART,Mahmoud AA,Omar AR

更新日期：2020-11-11 00:00:00

abstract：:Network structure has often proven to be important in understanding the decision behavior of individuals or agents in different interdependent situations. Computational studies predict that network structure has a crucial influence on behavior in iterated 2 by 2 asymmetric 'battle of the sexes' games. We test such beh...

journal_title：Scientific reports

authors： Broere J,Buskens V,Stoof H,Sánchez A

更新日期：2019-05-02 00:00:00

abstract：:Liquid pumping can occur along the outer surface of an electrode under a DC electric field. For biological applications, a better understanding of the ionic solution pumping mechanism is required. Here, we fabricated CNT wire electrodes (CWEs) and tungsten wire electrodes (TWEs) of various diameters to assess an ionic...

journal_title：Scientific reports

authors： Shin JH,Kim GH,Kim I,Jeon H,An T,Lim G

更新日期：2015-07-02 00:00:00

abstract：:In cytochrome c oxidase (CytcO) reduction of O2 to water is linked to uptake of eight protons from the negative side of the membrane: four are substrate protons used to form water and four are pumped across the membrane. In bacterial oxidases, the substrate protons are taken up through the K and the D proton pathways,...

journal_title：Scientific reports

authors： Björck ML,Vilhjálmsdóttir J,Hartley AM,Meunier B,Näsvik Öjemyr L,Maréchal A,Brzezinski P

更新日期：2019-12-27 00:00:00

abstract：:Cyanobacteria are attractive microbial hosts for production of chemicals using light and CO2. However, their low productivity of chemicals is a major challenge for commercial applications. This is mostly due to their relatively slow growth rate and carbon partitioning toward biomass rather than products. Many cyanobac...

journal_title：Scientific reports

authors： Lin PC,Zhang F,Pakrasi HB

更新日期：2020-01-15 00:00:00

abstract：:Although graphene is a typical two dimensional materials, it has converted to multi-dimensional materials with many unique properties. As an example, the one dimensional graphene fiber is fabricated by utilizing ionic liquid as coagulation and functional diamines as cross-linkers to connect graphene oxide layers. The ...

journal_title：Scientific reports

authors： Fan T,Zhao C,Xiao Z,Guo F,Cai K,Lin H,Liu Y,Meng H,Min Y,Epstein AJ

更新日期：2016-07-08 00:00:00

abstract：:At the regional scale, although environmental factors are known to shape the distributions of belowground communities in terrestrial ecosystems, these environmental factors account for relatively low percentages of the variation in belowground communities. More of this variation might be explained by considering ecosy...

journal_title：Scientific reports

authors： Wang B,Wu Y,Chen D

更新日期：2017-08-04 00:00:00

abstract：:The enzyme browning reaction results in grey speckles on tobacco leaves, which impairs the value and industrial usability of tobacco leaves. To demonstrate the influences of different browning degrees (BDs) of tobacco leaves on the usability of different cultivars and positions and identified structure of brown (grey)...

journal_title：Scientific reports

authors： Chen Y,Zhou J,Ren K,Zou C,Liu J,Yao G,He J,Zhao G,Huang W,Hu B,Chen Y,Xiong K,Jin Y

更新日期：2019-11-28 00:00:00

abstract：:Gaussia luciferase (GLuc) is a small luciferase (18.2 kDa; 168 residues) and is thus attracting much attention as a reporter protein, but the lack of structural information is hampering further application. Here, we report the first solution structure of a fully active, recombinant GLuc determined by heteronuclear mul...

journal_title：Scientific reports

authors： Wu N,Kobayashi N,Tsuda K,Unzai S,Saotome T,Kuroda Y,Yamazaki T

更新日期：2020-11-18 00:00:00

abstract：:Inorganic elements are important components of medicinal herbs, and provide valuable experimental evidence for the quality evaluation and control of traditional Chinese medicine (TCM). In this study, to investigate the relationship between the inorganic elemental fingerprint and geographical origin identification of c...

journal_title：Scientific reports

authors： Zhao Y,Ma X,Fan L,Mao F,Tian H,Xu R,Cao Z,Zhang X,Fu X,Sui H

更新日期：2017-10-03 00:00:00

abstract：:Hymenoptera venom allergy can cause severe anaphylaxis in untreated patients. Polistes dominula is an important elicitor of venom allergy in Southern Europe as well as in the United States. Due to its increased spreading to more moderate climate zones, Polistes venom allergy is likely to gain importance also in these ...

journal_title：Scientific reports

authors： Schiener M,Hilger C,Eberlein B,Pascal M,Kuehn A,Revets D,Planchon S,Pietsch G,Serrano P,Moreno-Aguilar C,de la Roca F,Biedermann T,Darsow U,Schmidt-Weber CB,Ollert M,Blank S

更新日期：2018-01-22 00:00:00

abstract：:Philanthotoxin-433 (PhTX-433) is an active component of the venom from the Egyptian digger wasp, Philanthus triangulum. PhTX-433 inhibits several excitatory ligand-gated ion channels, and to improve selectivity two synthetic analogues, PhTX-343 and PhTX-12, were developed. Previous work showed a 22-fold selectivity of...

journal_title：Scientific reports

authors： Kachel HS,Patel RN,Franzyk H,Mellor IR

更新日期：2016-11-30 00:00:00

abstract：:The apolipoprotein B mRNA editing catalytic polypeptide-like (APOBEC) family proteins bind RNA and single-stranded DNA, and create C-to-U base modifications through cytidine deaminase activity. APOBEC3G restricts human immunodeficiency virus 1 (HIV-1) infection by creating hypermutations in proviral DNA, while HIV-1-e...

journal_title：Scientific reports

authors： Chen R,Zhao X,Wang Y,Xie Y,Liu J

更新日期：2017-01-18 00:00:00

abstract：:Autotaxin (ATX) is a secreted enzyme metabolized by liver sinusoidal endothelial cells that has been associated with liver fibrosis. We evaluated serum ATX values in 128 treatment-naïve, histologically assessed primary biliary cholangitis (PBC) patients and 80 healthy controls for comparisons of clinical parameters in...

journal_title：Scientific reports

authors： Joshita S,Umemura T,Usami Y,Yamashita Y,Norman GL,Sugiura A,Yamazaki T,Fujimori N,Kimura T,Matsumoto A,Igarashi K,Yoshizawa K,Ota M,Tanaka E

更新日期：2018-05-25 00:00:00

abstract：:The quest to 'forward-engineer' and fabricate biological machines remains a grand challenge. Towards this end, we have fabricated locomotive "bio-bots" from hydrogels and cardiomyocytes using a 3D printer. The multi-material bio-bot consisted of a 'biological bimorph' cantilever structure as the actuator to power the ...

journal_title：Scientific reports

authors： Chan V,Park K,Collens MB,Kong H,Saif TA,Bashir R

更新日期：2012-01-01 00:00:00

abstract：:RNA-sequencing has become the gold standard for whole-transcriptome gene expression quantification. Multiple algorithms have been developed to derive gene counts from sequencing reads. While a number of benchmarking studies have been conducted, the question remains how individual methods perform at accurately quantify...

journal_title：Scientific reports

authors： Everaert C,Luypaert M,Maag JLV,Cheng QX,Dinger ME,Hellemans J,Mestdagh P

更新日期：2017-05-08 00:00:00

abstract：:Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivi...

journal_title：Scientific reports

authors： Wang Z,Ju J,Wang J,Yin W,Chen R,Li M,Jin C,Tang X,Lee D,Yan A

更新日期：2016-12-06 00:00:00

abstract：:The aim of this study is to develop an internal-external correlation model for internal motion estimation for lung cancer radiotherapy. Deformation vector fields that characterize the internal-external motion are obtained by respectively registering the internal organ meshes and external surface meshes from the 4DCT i...

journal_title：Scientific reports

authors： Chen H,Zhong Z,Yang Y,Chen J,Zhou L,Zhen X,Gu X

更新日期：2018-02-27 00:00:00

abstract：:Biocontrol offers a promising alternative to synthetic fungicides for the control of a variety of pre- and post-harvest diseases of crops. Black rot, which is caused by the pathogenic fungus Ceratocytis fimbriata, is the most destructive post-harvest disease of sweet potato, but little is currently known about potenti...

journal_title：Scientific reports

authors： Jiang L,Jeong JC,Lee JS,Park JM,Yang JW,Lee MH,Choi SH,Kim CY,Kim DH,Kim SW,Lee J

更新日期：2019-11-08 00:00:00

abstract：:We aimed to assess feasibility of a support vector machine (SVM) texture classifier to discriminate pathologic infiltration patterns from the normal bone marrows in MRI. This retrospective study included 467 cases, which were split into a training (n = 360) and a test set (n = 107). A sagittal T1-weighted lumbar spina...

journal_title：Scientific reports

authors： Hwang EJ,Jung JY,Lee SK,Lee SE,Jee WH

更新日期：2019-04-15 00:00:00