A novel sample holder for 4D live cell imaging to study cellular dynamics in complex 3D tissue cultures.

abstract：:Kuding tea is implicated in alleviating metabolic disorders in traditional Chinese medicine. However, the role of Ilex latifolia Thunb (kuding tea), one of the large leaf kuding tea species, in the prevention of the development of obesity remains to be determined. We show here that 7-week-old male mice treated with an...

journal_title：Scientific reports

authors： Wu H,Chen YL,Yu Y,Zang J,Wu Y,He Z

更新日期：2017-11-07 00:00:00

abstract：:Functional interplays of microbial activity, genetic diversity and contaminant transformation are poorly understood in reactors for mineralizing halogenated aromatics anaerobically. Here, we investigated abundance and distribution of potential microbes and functional genes associated with pentachlorophenol (PCP) anaer...

journal_title：Scientific reports

authors： Li ZL,Nan J,Huang C,Liang B,Liu WZ,Cheng HY,Zhang C,Zhang D,Kong D,Kanamaru K,Kobayashi T,Wang AJ,Katayama A

更新日期：2016-01-11 00:00:00

abstract：:In the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression...

journal_title：Scientific reports

authors： Reclusa P,Verstraelen P,Taverna S,Gunasekaran M,Pucci M,Pintelon I,Claes N,de Miguel-Pérez D,Alessandro R,Bals S,Kaushal S,Rolfo C

更新日期：2020-04-16 00:00:00

abstract：:In this study, electromechanical characteristics of (1-x) Bi0.5Na0.5TiO3-xSrTiO3 (ST26, x = 0.26)/(1-y) Bi0.5Na0.5TiO3-ySrTiO3 (ST10, y = 0.1) (matrix/seed) composites were studied. The ST26 (high relaxor phase) and ST10 (a relaxor ferroelectric (RF), high ferroelectric phase) composite with large (r-ST26-ST10) and sm...

journal_title：Scientific reports

authors： Saleem M,Hwan LD,Kim IS,Kim MS,Maqbool A,Nisar U,Pervez SA,Farooq U,Farooq MU,Khalil HMW,Jeong SJ

更新日期：2018-09-20 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease and a major health problem in the elderly population. No disease-modifying osteoarthritis drug (DMOAD) has been made available for clinical use. Here we present a disease-modifying strategy for OA, focusing on messenger RNA (mRNA) delivery of a therapeutic tr...

journal_title：Scientific reports

authors： Aini H,Itaka K,Fujisawa A,Uchida H,Uchida S,Fukushima S,Kataoka K,Saito T,Chung UI,Ohba S

更新日期：2016-01-05 00:00:00

abstract：:Ambient seismic noise is characterized by randomness incurred by the random position and strength of the noise sources as well as the heterogeneous properties of the medium through which it propagates. Here we use ambient noise data recorded prior to the 1996 Gjálp eruption in Iceland in order to show that a reduction...

journal_title：Scientific reports

authors： Glynn CC,Konstantinou KI

更新日期：2016-11-24 00:00:00

abstract：:Aldosterone and the Mineralocorticoid Receptor (MR) control hydroelectrolytic homeostasis and alterations of mineralocorticoid signaling pathway are involved in the pathogenesis of numerous human diseases, justifying the need to decipher molecular events controlling MR expression level. Here, we show in renal cells th...

journal_title：Scientific reports

authors： Lema I,Amazit L,Lamribet K,Fagart J,Blanchard A,Lombès M,Cherradi N,Viengchareun S

更新日期：2017-07-06 00:00:00

abstract：:Perpendicular magnetization and precise control over the magnetic easy axis in magnetic thin film is necessary for a variety of applications, particularly in magnetic recording media. A strong (111) orientation is successfully achieved in the CoFe2O4 (CFO) thin film at relatively low substrate temperature of 100 °C, w...

journal_title：Scientific reports

authors： Shirsath SE,Liu X,Yasukawa Y,Li S,Morisako A

更新日期：2016-07-20 00:00:00

abstract：:Reperfusion alters post-myocardial infarction (MI) healing; however, very few systematic studies report the early molecular changes following ischemia/reperfusion (I/R). Alterations in the remote myocardium have also been neglected, disregarding its contribution to post-MI heart failure (HF) development. This study ch...

journal_title：Scientific reports

authors： Binek A,Fernández-Jiménez R,Jorge I,Camafeita E,López JA,Bagwan N,Galán-Arriola C,Pun A,Agüero J,Fuster V,Ibanez B,Vázquez J

更新日期：2017-09-27 00:00:00

abstract：:The Internet of Things is driving extensive efforts to develop intelligent everyday objects. This requires seamless integration of relatively simple electronics, for example through 'stick-on' electronics labels. We believe the future evolution of this technology will be governed by Wright's Law, which was first propo...

journal_title：Scientific reports

authors： Myny K,Smout S,Rockelé M,Bhoolokam A,Ke TH,Steudel S,Cobb B,Gulati A,Gonzalez Rodriguez F,Obata K,Marinkovic M,Pham DV,Hoppe A,Gelinck GH,Genoe J,Dehaene W,Heremans P

更新日期：2014-12-10 00:00:00

abstract：:Biomass waste products from green algae have recently been given new life, as these polysaccharides have potential applications in industry, agriculture, and medicine. One such polysaccharide group called ulvans displays many different, potentially useful properties that arise from their structural versatility. Hence,...

journal_title：Scientific reports

authors： Melcher RL,Neumann M,Fuenzalida Werner JP,Gröhn F,Moerschbacher BM

更新日期：2017-03-22 00:00:00

abstract：:Soil microbial communities directly affect soil functionality through their roles in the cycling of soil nutrients and carbon storage. Microbial communities vary substantially in space and time, between soil types and under different land management. The mechanisms that control the spatial distributions of soil microb...

journal_title：Scientific reports

authors： Xue PP,Carrillo Y,Pino V,Minasny B,McBratney AB

更新日期：2018-08-06 00:00:00

abstract：:Agr family includes three groups of genes, Ag1, Agr2 and Agr3, which encode the thioredoxin domain-containing secreted proteins and have been shown recently to participate in regeneration of the amputated body appendages in amphibians. By contrast, higher vertebrates have only Agr2 and Agr3, but lack Ag1, and have low...

journal_title：Scientific reports

authors： Ivanova AS,Shandarin IN,Ermakova GV,Minin AA,Tereshina MB,Zaraisky AG

更新日期：2015-01-29 00:00:00

abstract：:Nutrient resorption processes in the plants infected by pathogen remain poorly understood. Huanglongbing (HLB) is a destructive disease of citrus. HLB-pathogen 'Candidatus Liberibacter asiaticus' grows specifically in the phloem of hosts and may cause problems in the plant vascular system after infection. Therefore, i...

journal_title：Scientific reports

authors： Cao J,Cheng C,Yang J,Wang Q

更新日期：2015-09-30 00:00:00

abstract：:Mustard aphid, also known as turnip aphid (Lipaphis erysimi) is a major insect pest of rapeseed-mustard group of crops. Tremendous economic significance has led to substantial basic research involving gene-expression studies in this insect species. In qRT-PCR analysis of gene-expression, normalization of data against ...

journal_title：Scientific reports

authors： Koramutla MK,Aminedi R,Bhattacharya R

更新日期：2016-05-11 00:00:00

abstract：:Early detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary comp...

journal_title：Scientific reports

authors： Tay SY,Chang PY,Lao WT,Lin YC,Chung YH,Chan WP

更新日期：2017-12-15 00:00:00

abstract：:Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases, however, can provide patients and carers with the chance of early intervention, bet...

journal_title：Scientific reports

authors： Li Y,Rao S,Solares JRA,Hassaine A,Ramakrishnan R,Canoy D,Zhu Y,Rahimi K,Salimi-Khorshidi G

更新日期：2020-04-28 00:00:00

abstract：:Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals. The microbiome has circadian rhythmicity and helps the host circadian clock function. We investigated the ef...

journal_title：Scientific reports

authors： Tahara Y,Yamazaki M,Sukigara H,Motohashi H,Sasaki H,Miyakawa H,Haraguchi A,Ikeda Y,Fukuda S,Shibata S

更新日期：2018-01-23 00:00:00

abstract：:Patient misidentification in imaging examinations has become a serious problem in clinical settings. Such misidentification could be prevented if patient characteristics such as sex, age, and body weight could be predicted based on an image of the patient, with an alert issued when a mismatch between the predicted and...

journal_title：Scientific reports

authors： Kawauchi K,Hirata K,Katoh C,Ichikawa S,Manabe O,Kobayashi K,Watanabe S,Furuya S,Shiga T

更新日期：2019-05-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xu X,Zhao J,Wang M,Wang L,Yang J

更新日期：2020-02-06 00:00:00

abstract：:The use of cardiac troponins (cTn) is the gold standard for diagnosing myocardial infarction. Independent of myocardial infarction (MI), however, sex, age and kidney function affect cTn levels. Here we developed a method to adjust cTnI levels for age, sex, and renal function, maintaining a unified cut-off value such a...

journal_title：Scientific reports

authors： Boeckel JN,Palapies L,Klotsche J,Zeller T,von Jeinsen B,Perret MF,Kleinhaus SL,Pieper L,Tzikas S,Leistner D,Bickel C,Stalla GK,Lehnert H,Lindahl B,Wittchen HU,Silber S,Baldus S,Maerz W,Dimmeler S,Blankenberg S,Mün

更新日期：2018-05-24 00:00:00

abstract：:With the continuous urbanization and industrialization in the world, energy saving and greenhouse gas (GHG) emission reduction have been serious issues to be addressed, for which heat recovery from traditional energy-intensive industries makes up a significant strategy. Here we report a novel approach to extract the w...

journal_title：Scientific reports

authors： Sun Y,Sridhar S,Liu L,Wang X,Zhang Z

更新日期：2015-11-12 00:00:00

abstract：:We report low-temperature solution-processed p-CuO nanorods (NRs)/n-ZnO NRs heterojunction light emitting diode (LED), exploiting the native point defects of ZnO NRs. ZnO NRs were synthesized at 90 °C by using hydrothermal method while CuO NRs were synthesized at 100 °C by using microwave reaction system. The electric...

journal_title：Scientific reports

authors： Biswas P,Baek SD,Lee SH,Park JH,Lee SJ,Lee TI,Myoung JM

更新日期：2015-12-09 00:00:00

abstract：:In this paper, one kind of novel non-periodic spoof surface plasmon polaritons (SSPPs) with H-shaped cells is proposed. As we all know, the cutoff frequency exists inherently for the conventional comb-shaped SSPPs, which is a kind of periodic groove shape structures and fed by a conventional coplanar waveguide (CPW). ...

journal_title：Scientific reports

authors： Gao X,Che W,Feng W

更新日期：2018-02-06 00:00:00

abstract：:While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infecti...

journal_title：Scientific reports

authors： Ma MJ,Yang XX,Qian YH,Zhao SY,Hua S,Wang TC,Chen SH,Ma GY,Sang XY,Liu LN,Wu AP,Jiang TJ,Gao YW,Gray GC,Zhao T,Ling X,Wang JL,Lu B,Qian J,Cao WC

更新日期：2014-12-23 00:00:00

abstract：:Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag, following cataract removal. Standard IOLs allow the anterior and...

journal_title：Scientific reports

authors： Eldred JA,McDonald M,Wilkes HS,Spalton DJ,Wormstone IM

更新日期：2016-04-14 00:00:00

abstract：:The accurate prediction of the impact of an amino acid substitution on the thermal stability of a protein is a central issue in protein science, and is of key relevance for the rational optimization of various bioprocesses that use enzymes in unusual conditions. Here we present one of the first computational tools to ...

journal_title：Scientific reports

authors： Pucci F,Bourgeas R,Rooman M

更新日期：2016-03-18 00:00:00

abstract：:Fungal pathogens represent a significant threat to immunocompromised patients or individuals with traumatic injury. Strategies to efficiently remove fungal spores from hospital surfaces and, ideally, patient skin thus offer the prospect of dramatically reducing infections in at-risk patients. Photodynamic inactivation...

journal_title：Scientific reports

authors： Trzaska WJ,Wrigley HE,Thwaite JE,May RC

更新日期：2017-07-04 00:00:00

abstract：:HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myeloid-derived suppressor cells (MDSCs), a heterogeneous population of immature m...

journal_title：Scientific reports

authors： Thakuri BKC,Zhang J,Zhao J,Nguyen LN,Nguyen LNT,Khanal S,Cao D,Dang X,Schank M,Wu XY,Morrison ZD,Gazzar ME,Li Z,Jiang Y,Ning S,Wang L,Moorman JP,Yao ZQ

更新日期：2020-12-16 00:00:00

abstract：:Coral reefs around the world are undergoing severe decline in the past few decades. Mass coral mortalities have predominantly been reported to be caused by coral bleaching or disease outbreaks. Temporary hypoxic conditions caused by algal blooms can trigger mass coral mortalities though are reported rarely. In this st...

journal_title：Scientific reports

authors： Raj KD,Mathews G,Obura DO,Laju RL,Bharath MS,Kumar PD,Arasamuthu A,Kumar TKA,Edward JKP

更新日期：2020-12-17 00:00:00