Screening key candidate genes and pathways involved in insulinoma by microarray analysis.

abstract：BACKGROUND:Chronic lymphocytic leukemia (CLL) is a rare hematological malignancy classified in the non-Hodgkin's lymphoma category. Ibrutinib, a first-in-class Bruton tyrosine kinase inhibitor has been approved for use in the treatment of CLL. This drug has shown beneficial effects including a higher overall response r...

journal_title：Medicine

authors： Zhou Y,Lu H,Yang M,Xu C

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Acute chronic liver failure (ACLF) is the most common type of liver failure. The clinical symptoms are complex and changeable, the treatment is difficult and the fatality rate is high. It has become an urgent problem to actively seek effective treatment means and improve the clinical efficacy of ACLF patient...

journal_title：Medicine

authors： Chen Y,Luo Y,Wu F,Liao N,Shi Q,Mao D

更新日期：2020-10-09 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. However, its etiology and fundamental pathophysiology for the disease process are poorly understood. In this study, we thus used bioinformatics to identify candidate genes potentially causative of severe NAFLD. ME...

journal_title：Medicine

authors： Qi S,Wang C,Li C,Wang P,Liu M

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Nowadays, psychiatric morbidities are more and more common, which imposes huge social and economic burden on all countries across the world. Mental illnesses are found to be related to genetics. Over the past few years, a large number of risk genes and loci related to psychiatric morbidities have been report...

journal_title：Medicine

authors： Su J,Liu P,Liu B,Zhang Y

更新日期：2020-11-06 00:00:00

abstract：:Vitamin D deficiency is associated with numerous public health issues. Limited data are available for children in southern China, a region that receives abundant sunlight. We aimed to estimate the 25-hydroxyvitamin D (25(OH)D) levels in children in that area, and to determine seasonal variations in serum 25(OH)D level...

journal_title：Medicine

authors： Guo Y,Ke HJ,Liu Y,Fu M,Ning J,Yu L,Xiao Y,Che D,Chen XY,Deng YH,Wu JL

更新日期：2018-06-01 00:00:00

abstract：RATIONALE:Adult patients with Down syndrome (DS) commonly develop Hashimoto thyroiditis (HT). However, primary diffuse large B-cell lymphoma (DLBCL) of the thyroid is uncommon, and its simultaneous occurrence with HT is very rare. To our knowledge, coexisting DLBCL and HT in a patient with DS has not been reported in t...

journal_title：Medicine

authors： Wei L,Zhao N,Li Y,Zheng X,Zhang H,Zhang Z

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that single-nucleotide polymorphisms (SNPs) in miRNAs are related to the susceptibility to brain tumors, but the conclusions remain controversial. This study was to perform a meta-analysis to re-assess the associations between miRNA SNPs and brain tumor risk. METHODS:Relev...

journal_title：Medicine

authors： Gao F,Zhu Y

更新日期：2019-08-01 00:00:00

abstract：RATIONALE:Sarcomatous or anaplastic carcinoma mural nodules presenting in ovarian mucinous cystic tumors are very rare. Here, we reported the ultrasonic and pathological features of 2 such cases. PATIENT CONCERNS:A 60-year-old woman presented with a complaint of lower abdominal pain. Physical examination revealed a ha...

journal_title：Medicine

authors： Zhang Y,Yuan Z,Sun K,Li P

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Mycoplasma pneumoniae (MP) infection in infants is usually overlooked and it might result in important complications if left untreated. MP-induced arthritis is probably the least common extrapulmonary manifestation and frequently leads to delays in the diagnosis. PATIENT CONCERNS:We report the case of a 2...

journal_title：Medicine

authors： Mărginean CO,Georgescu AM,Meliţ LE

更新日期：2021-01-15 00:00:00

abstract：:Recently, much attention has been paid to a potential biochemical cross-talk between the metabolism of the adipose tissue (AT) and bone (marrow), termed "bone-fat axis." We hypothesized that selected substances, participating in this "dialog," are associated with body mass and peripheral trafficking of bone marrow-der...

journal_title：Medicine

authors： Blogowski W,Dolegowska K,Deskur A,Dolegowska B,Starzyńska T

更新日期：2015-08-01 00:00:00

abstract：:Informed consent has now become common in medical practice. However, a gap still exists between doctors and patients in the understanding of clinical conditions. We designed medical comics about "subarachnoid hemorrhage" and "intracerebral hemorrhage" to help doctors obtain informed consent intuitively, quickly, and c...

journal_title：Medicine

authors： Furuno Y,Sasajima H

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:Injection laryngoplasty is a common procedure for patients with vocal fold dysfunction, but the literature on its benefits has been mainly focused on those related to structural lesions or laryngeal nerve involvement. Stroke patients may be at increased risk of aspiration due to insufficient vocal fold mot...

journal_title：Medicine

authors： Han YJ,Jang YJ,Park GY,Joo YH,Im S

更新日期：2020-02-01 00:00:00

abstract：:Osteoporosis is a systemic disorder predominantly affecting postmenopausal women but also men at an advanced age. Both genders may suffer from low-energy fractures of, for example, the proximal humerus when reduction of the bone stock or/and quality has occurred.The aim of the current study was to compare the amount o...

journal_title：Medicine

authors： Sprecher CM,Schmidutz F,Helfen T,Richards RG,Blauth M,Milz S

更新日期：2015-12-01 00:00:00

abstract：:Mucinous adenocarcinoma (MAC) is a histological subtype of colorectal cancer. The oncologic behavior of MAC differs from nonmucinous adenocarcinoma (non-MAC). Our aim in this study was to characterize patients with colorectal MAC through evaluation of a large, institutional-based cohort with long-term follow-up. A tot...

journal_title：Medicine

authors： Park JS,Huh JW,Park YA,Cho YB,Yun SH,Kim HC,Lee WY,Chun HK

更新日期：2015-04-01 00:00:00

abstract：RATIONALE:Splenosis is the heterotopic auto-transplantation of the splenic tissues. Gastric splenosis in a rare location mimics a gastrointestinal stromal tumor (GIST). Gastric splenosis with hemangioma has not been reported throughout the literature. PATIENT CONCERNS:We report a case of a 74-year-old schistosomiasis ...

journal_title：Medicine

authors： Guan B,Li XH,Wang L,Zhou M,Dong ZW,Luo GJ,Meng LP,Hu J,Jin WY

更新日期：2018-07-01 00:00:00

abstract：RATIONALE:Subcutaneous implantable electrocardiographs are highly effective in detecting covert atrial fibrillation (AF) in cryptogenic stroke. However, these invasive devices are not indicated for all cryptogenic stroke patients, and noninvasive improvements over conventional Holter-type ambulatory electrocardiography...

journal_title：Medicine

authors： Akiyama H,Nukui S,Araga T,Hoshino M,Tanaka K,Kashima S,Sasaki R,Uchino K,Hasegawa Y

更新日期：2017-02-01 00:00:00

abstract：:Blood glucose control in patients with diabetes mellitus (DM) is reportedly influenced by the seasons, with hemoglobin A1c (HbA1c) levels decreasing in the summer or warm season and increasing in the winter or cold season. In addition, several studies have shown that sepsis is also associated with the seasons. Althoug...

journal_title：Medicine

authors： Tsujimoto T,Yamamoto-Honda R,Kajio H,Kishimoto M,Noto H,Hachiya R,Kimura A,Kakei M,Noda M

更新日期：2014-11-01 00:00:00

abstract：:The present study investigated the effectiveness of a Carisolv III + 0.5% sodium hypochlorite (NaOCl)-based root canal irrigant for smear layer removal.Forty maxillary incisors were randomly divided into 4 groups (n = 10 per group). The canals in group A (experimental) were prepared with 0.5% NaOCl, and Carisolv III a...

journal_title：Medicine

authors： Wu D,Ma YZ,Jia J,Xin BC,Wang DS,Sun DG,Wang LX

更新日期：2020-05-29 00:00:00

abstract：:Short Synacthen test (SST) involves measuring the baseline, 30-, and 60-minute serum cortisol levels, after injecting 250 μg of synthetic adrenocorticotropic hormone or Synacthen (ACTH). This study aimed to review the current clinical practice of performing SST to establish a standardized test protocol and to addition...

journal_title：Medicine

authors： Butt MI,Alzuhayri N,Amer L,Riazuddin M,Aljamei H,Khan MS,Abufarhaneh M,Alrajhi E,Alnassar A,Alahmed R,Aljayar DMA,Abothenain FF,De Vol E

更新日期：2020-10-23 00:00:00

abstract：RATIONALE:Capecitabine (CAP) is a chemotherapeutic agent used to treat breast and gastrointestinal cancers. The most common adverse reactions of CAP primarily included gastrointestinal and dermatological effects. Whereas, the CAP-induced fatty liver had never been reported. PATIENT CONCERNS:In this study, a-69-year ol...

journal_title：Medicine

authors： Jiang Y,He Q,Li S,Shi C,Yang X

更新日期：2017-11-01 00:00:00

abstract：:Multiple myeloma (MM) is a plasma cell neoplasm with skeletal destruction which could also spread to extramedullary regions. Common diagnostic imaging modalities include skeletal radiography, computed tomography (CT), magnetic resonance imaging (MRI). Recently, PET/CT is proposed as an ideal tomographic tool for diagn...

journal_title：Medicine

authors： Tsai SY,Wang SY,Shiau YC,Wu YW

更新日期：2015-06-01 00:00:00

abstract：:Clients of female sex workers (CFSWs) are a bridge population for the spread of HIV and syphilis to low or average risk heterosexuals. Most studies have examined the point prevalence of these infections in CFSWs. Limited evidence suggests that older age CFSWs are at a higher risk of acquiring sexually transmitted dise...

journal_title：Medicine

authors： Chen Y,Abraham Bussell S,Shen Z,Tang Z,Lan G,Zhu Q,Liu W,Tang S,Li R,Huang W,Huang Y,Liang F,Wang L,Shao Y,Ruan Y

更新日期：2016-05-01 00:00:00

abstract：:Human papillomavirus (HPV) infection is a crucial health problem and caused substantial malignancy diseases among female worldwide. We aim to investigate the distribution of HPV subtype and the status of cervical cancer and precancerous lesions caused by HPV infection in North China Plain population. A total of 61,870...

journal_title：Medicine

authors： Liu L,Wang D,Dong H,Jin C,Jiang L,Song H,Jin C,Wang T,Shi C,Yang L,Wang Y

更新日期：2019-09-01 00:00:00

abstract：:The aim of this study was to evaluate the correlation between radionuclide salivagram findings and clinical characteristics in stroke patient with swallowing difficulty.In this study, dysphagic stroke patients who had undergone both a radionuclide salivagram and videofluoroscopic swallowing study (VFSS) were included ...

journal_title：Medicine

authors： Yu KJ,Park D

更新日期：2019-03-01 00:00:00

abstract：:Many studies suggest that catalase C-262T gene polymorphism is associated with cancer risk, but with inconsistent results. This study aimed to summarize the overall association between catalase C-262T polymorphism and cancer risk. Literature search was performed in PubMed, Embase, and other databases, studies regardin...

journal_title：Medicine

authors： Shen Y,Li D,Tian P,Shen K,Zhu J,Feng M,Wan C,Yang T,Chen L,Wen F

更新日期：2015-04-01 00:00:00

abstract：:The aim of this study was to investigate the relationships between blood-brain barrier (BBB) dysfunction, intrathecal IgG synthesis, and brain glucose consumption as detectable by means of serum/cerebrospinal fluid (CSF) albumin index (Qalb) and IgG index [(CSF IgG/serum IgG) × Serum albumin/CSF albumin)] and 2-deoxy-...

journal_title：Medicine

authors： Chiaravalloti A,Fiorentini A,Francesco U,Martorana A,Koch G,Belli L,Toniolo S,Di Pietro B,Motta C,Schillaci O

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:Currently, the options are limited for the treatment of patients who have failed 2 lines of chemotherapy for advanced lung squamous cell carcinoma (SCC). Recently, nivolumab, a fully human IgG4 programmed death 1 immune checkpoint inhibitor antibody, was approved to treat patients with advanced stage, rela...

journal_title：Medicine

authors： Pi G,He H,Bi J,Li Y,Li Y,Zhang Y,Wang M,Han G,Lin C

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to summarize current evidence evaluating the association between antenatal infection and intraventricular hemorrhage (IVH) in preterm infants. MATERIALS AND METHODS:We searched for published articles on antenatal infection and IVH in 3 English (PubMed, the Cochrane Library, and EBS...

journal_title：Medicine

authors： Huang J,Meng J,Choonara I,Xiong T,Wang Y,Wang H,Qu Y,Mu D

更新日期：2019-08-01 00:00:00

abstract：RATIONALE:Congenital myasthenic syndrome (CMSs) are a group of rare genetic disorders of the neurological junction, which can result in structural or functional weakness. Here, we characterized a case of CMS in order to clarify the diagnosis and expand the understanding of it. The molecular diagnosis had implications f...

journal_title：Medicine

authors： Yang K,Cheng H,Yuan F,Meng L,Yin R,Zhang Y,Wang S,Wang C,Lu Y,Xi J,Lu Q,Chen Y

更新日期：2018-04-01 00:00:00

abstract：:Serum adiponectin levels have been suggested to be predictors of type 2 diabetes mellitus in diverse populations. However, the relationship between circulating adiponectin levels and the risk of development of type 2 diabetes in postmenopausal women has not been investigated.A total of 382 healthy postmenopausal women...

journal_title：Medicine

authors： Darabi H,Raeisi A,Kalantarhormozi MR,Ostovar A,Assadi M,Asadipooya K,Vahdat K,Dobaradaran S,Nabipour I

更新日期：2015-08-01 00:00:00