Abstract:
:Many studies suggest that catalase C-262T gene polymorphism is associated with cancer risk, but with inconsistent results. This study aimed to summarize the overall association between catalase C-262T polymorphism and cancer risk. Literature search was performed in PubMed, Embase, and other databases, studies regarding the association between catalase C-262T polymorphism and cancer risk were identified, and data were retrieved and analyzed by using Review Manager 5.0.24 and STATA 12.0. A total of 18 publications with 22 case-control studies, including 9777 cancer patients and 12,223 controls, met the inclusion criteria. Meta-analysis results showed significant association between catalase C-262 T polymorphism and cancer risk (TT vs CT + CC: odds ratio [OR] = 1.17, 95% confidence interval [CI] = 1.03-1.31, P = 0.01). Subgroup analyses stratified by cancer types suggested the catalase C-262T polymorphism was significantly associated with an increased prostate cancer risk (TT vs CT + CC: OR = 1.61, 95% CI = 1.17-2.22, P = 0.004); for subgroup analyses stratified by ethnicity, no associations between this polymorphism and Asians or whites were identified (CT + TT vs CC: OR = 1.11, 95% CI = 0.98-1.26, P = 0.09 for whites; OR = 1.19, 95% CI = 0.78-1.80, P = 0.42 for Asians). In summary, the catalase C-262T polymorphism may be a risk factor for cancer with cancer type-specific effects. Further studies should be performed to confirm these findings.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Shen Y,Li D,Tian P,Shen K,Zhu J,Feng M,Wan C,Yang T,Chen L,Wen Fdoi
10.1097/MD.0000000000000679subject
Has Abstractpub_date
2015-04-01 00:00:00pages
e679issue
13eissn
0025-7974issn
1536-5964pii
00005792-201504010-00013journal_volume
94pub_type
杂志文章,meta分析,评审相关文献
MEDICINE文献大全abstract:RATIONALE:Penetrating neck traumas are dangerous and have a high mortality rate, particularly in patients with common carotid artery injuries. Advances in diagnostic imaging technology have shifted management of penetrating neck injuries from mandatory exploration to selective management. The question is now regarding ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015750
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:According to the mechanisms of action, combination therapy of anabolic and antiresorptive agents may produce more effect for the treatment of osteoporosis. However, the combination therapy of anabolic agents and bisphosphonates reports no benefit and even reduced the anabolic effects of anabolic agents. This...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000009534
更新日期:2017-12-01 00:00:00
abstract::There is an increased enthusiasm in treating osteolytic metastatic acetabulum via injecting polymethyl-methacrylate (PMMA) as a bone filler to provide pain relief and potential structural support. The aim of this respective study is to determine the function and quality of life improvement after cement acetabuloplasty...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017029
更新日期:2019-09-01 00:00:00
abstract::The objective of this study was to develop a venous computed tomography (CT)-based radiomics model to predict the lymph node metastasis (LNM) in patients with non-small cell lung cancer (NSCLC). A total of 411 consecutive patients with NSCLC underwent tumor resection and lymph node (LN) dissection from January 2018 to...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020074
更新日期:2020-05-01 00:00:00
abstract:RATIONALE:Invasive moles occur in the fertile period, with about 95% occurring after previous mole removal and the remaining 5% occurring after several other pregnancies. PATIENT CONCERNS:A 27-year-old patient developed a rare invasive mole two months after a missed abortion. DIAGNOSES:A transvaginal ultrasound scan ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017565
更新日期:2019-10-01 00:00:00
abstract:RATIONALE:Androgen insensitivity syndrome (CAIS) is a rare X-linked recessive androgen receptor disorder characterized by complete resistance to the actions of androgen in an individual with 46,XY karyotype. Metabolic disorder and diabetes has been rarely reported in these patients. PATIENT CONCERNS:A 22-year-old fema...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011353
更新日期:2018-08-01 00:00:00
abstract::Increasing numbers of patients with different types of dementia have resulted in the increasing medical care loads. It is not known whether explanatory factors for recurrent or prolong hospitalization were driven by the subtypes of dementia. We analyzed 203 dementia patients aged >65-year-old with a clinical diagnosis...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002091
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:This systematic review aims to explore the effectiveness and safety of extracorporeal shock-wave therapy (ESWT) for patients with frozen shoulder. METHODS:The sources of Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Web of Science,...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000014506
更新日期:2019-02-01 00:00:00
abstract:RATIONALE:Ossifying fibroma is benign fibro-osseous neoplasm. The authors report a case of ossifying fibroma in the mandibular angle suspected as metastasis of clear cell renal cell carcinoma. PATIENT CONCERNS:A 74-year-old man presented to the primary hospital complaining of frequent urination. A tumor in the left ki...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016595
更新日期:2019-08-01 00:00:00
abstract::Short Synacthen test (SST) involves measuring the baseline, 30-, and 60-minute serum cortisol levels, after injecting 250 μg of synthetic adrenocorticotropic hormone or Synacthen (ACTH). This study aimed to review the current clinical practice of performing SST to establish a standardized test protocol and to addition...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022621
更新日期:2020-10-23 00:00:00
abstract::We conducted a single-center retrospective study to compare the characteristics of Takayasu arteritis (TA) among white, North African, and black patients in a French tertiary care center (Hospital Pitié-Salpêtrière, Paris). Eighty-two patients were studied (82.9% female) during a median follow-up of 5.1 years (range, ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0b013e3181cba0a3
更新日期:2010-01-01 00:00:00
abstract:RATIONALE:Supernumerary teeth are those that teeth in excess number than the normal count. It is usually associated with genetic syndromes when present in more numbers. Several causal genes, such as APC, NHS, TRPS1, EVC and RUNX2, have been identified. However, etiology of supernumerary teeth remains largely unclear. ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000011328
更新日期:2018-08-01 00:00:00
abstract::This study investigated the impacts of renin-angiotensin system inhibitors (RASIs) on 2-year clinical outcomes in diabetes and dyslipidemic acute myocardial infarction (AMI) patients after a successful percutaneous coronary intervention (PCI) using newer-generation drug-eluting stents (DESs).A total of 16,997 AMI pati...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021289
更新日期:2020-07-24 00:00:00
abstract:BACKGROUND:The purpose of this study is to investigate the impact of cervical vascular ultrasound (CVU) combined transcranial Doppler ultrasound (TDU) in the diagnosis of cerebral infarction (CI). METHODS:The following electronic databases will be sought from PUBMED, EMBASE, Cochrane Library, PSYCINFO, Web of Science,...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019997
更新日期:2020-05-29 00:00:00
abstract:BACKGROUND:Currently, there is some clinical evidence supporting the use of acupuncture in alleviating pain and dysfunction in patients with lumbar spinal stenosis (LSS). However, the question of whether acupuncture could be efficacious for ageing patients remains unanswered. We designed a randomized controlled study t...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000021444
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:The Pharmaceutical industry sponsorship, research outcome and quality has been already evaluated for clinical trials in order to analyze if this kind of sponsorship affects the results of clinical trials. In this sense, this study has the aim to investigate whether placebo use allows positive outcomes regard...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022915
更新日期:2020-10-30 00:00:00
abstract::Pneumonic-type adenocarcinoma (P-ADC) is a subtype of lung adenocarcinoma with high mortality, which often requires lobectomy surgery. Nonsurgically treated P-ADC patients usually have more advanced or complex conditions, which remain poorly understood and pose a major challenge in clinical management. We aimed to des...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015420
更新日期:2019-05-01 00:00:00
abstract::Nonspecific ST-segment and T-wave (ST-T) changes represent one of the most prevalent electrocardiographic abnormalities in hypertensive patients. However, a limited number of studies have investigated the association between nonspecific ST-T changes and unsatisfactory blood pressure (BP) control in adults with hyperte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006423
更新日期:2017-03-01 00:00:00
abstract:RATIONALE:Primary central nervous system lymphoma (PCNSL) with initial manifestations of constipation and intestinal obstruction (IO) is rare. PATIENT CONCERNS:A 50-year-old Chinese male patient was admitted to the gastroenterology department due to constipation and abdominal distention for 8 days. He had experienced ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010080
更新日期:2018-03-01 00:00:00
abstract:ABSTRACT:The independent plastic surgery pathway recruits candidates with 5 years of surgical training who are typically more advanced in research than their integrated counterparts. Research productivity helps to discriminate between applicants. However, no studies exist detailing the academic attributes of matched in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023540
更新日期:2021-01-15 00:00:00
abstract::More than a decade has passed since the introduction of the concept that inhibition of platelet function may be helpful in preventing the initiation of thrombus formation. Aspirin has been recognized as inhibiting normal platelet function and the mechanism has been clearly delineated. Legions of patients have been stu...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-199105000-00001
更新日期:1991-05-01 00:00:00
abstract:RATIONALE:Unilateral manifestation of lymphedema during everolimus therapy has been described only rarely, mostly in transplant recipients. PATIENT CONCERNS:We report the first case of a patient who developed unilateral abdominal lymphedema, during a short period of everolimus treatment for renal cancer. DIAGNOSIS:Th...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022634
更新日期:2020-10-16 00:00:00
abstract::Cutaneous ulceration from sickle cell disease negatively impacts quality of life. Topical sodium nitrite has previously been shown to reduce the size of sickle leg ulcers. This study examined how topical sodium nitrite impacted the quality of life scores in patients with sickle leg ulcers.We prospectively collected da...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000012614
更新日期:2018-11-01 00:00:00
abstract::Meibomian gland dysfunction (MGD) is believed to be the leading cause of dry eye (DE) disease worldwide. The connection between aging and MGD has long been recognized. However, few studies have addressed the relationship between MGD and hormone replacement therapy (HRT) in perimenopausal women, and not have examined t...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004268
更新日期:2016-08-01 00:00:00
abstract:RATIONALE:IgG4-related disease is a newly recognized fibroinflammatory disorder, characterized by tumefactive lesions, storiform fibrosis and IgG4-positive plasma cells infiltration. IgG4-related sclerosing cholangitis (IgG4-SC) is the most common extrapancreatic manifestation of IgG4-related disease, but it is frequen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006542
更新日期:2017-04-01 00:00:00
abstract::African Americans (AA) with systemic sclerosis (SSc) have a worse prognosis compared to Americans of European descent (EA). We conducted the current study to test the hypothesis that AA patients with SSc have more severe disease and poorer outcomes compared to EA patients when afflicted with pulmonary arterial hyperte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000032
更新日期:2014-07-01 00:00:00
abstract::Continuous epidural block (CEB) is a popular clinical method for controlling postherpetic neuralgia (PHN). However, the long-term effects of CEB on PHN have not yet been established. This study aimed to confirm the clinical efficacy of epidural electrical stimulation catheters in CEB to manage PHN.Patients were classi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017026
更新日期:2019-09-01 00:00:00
abstract:RATIONALE:Coronary perforation leading to fistula directed to the right ventricle is a rare complication of percutaneous coronary intervention (PCI). The reported outcomes vary from a stable state to rapid deterioration. PATIENT CONCERNS:An 86-year-old man was diagnosed with non-ST elevation myocardial infarction, and...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014068
更新日期:2019-01-01 00:00:00
abstract::Treatment of latent tuberculosis infection (LTBI) is essential for eradicating tuberculosis (TB). Moreover, the patient adherence is crucial in determining the effectiveness of TB control. Isoniazid given by DOTS daily for 9 months (9H) is the standard treatment for LTBI in Taiwan. However, the completion rate is low ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004126
更新日期:2016-08-01 00:00:00
abstract::The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are not fully evaluated for the diagnosis of musculoskeletal tumors, especially spine tumors. The objective of our study was to assess the feasibility of NLR and PLR as indicators for pretreatment diagnosis of spine tumors.Patients who...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014902
更新日期:2019-04-01 00:00:00