Characteristics of carcinogenic HPV genotypes in North China Plain and the association with cervical lesions.

Abstract:

:Human papillomavirus (HPV) infection is a crucial health problem and caused substantial malignancy diseases among female worldwide. We aim to investigate the distribution of HPV subtype and the status of cervical cancer and precancerous lesions caused by HPV infection in North China Plain population. A total of 61,870 samples of outpatients and inpatients from January 2015 to May 2017 at the Affiliated Hospital of Jining Medical University were collected. All of the samples were tested by rapid flow-through hybridization HPV genotyping. Approximately 17,280 of the cases tested positive for HPV, indicating an infection rate of 27.9%. Approximately 7009 cases were compared to the results of cytological diagnosis. The top five HPV genotypes were HPV-16 (4.5%), HPV-52 (2.9%), HPV-58 (2.8%), HPV-53 (1.9%), and HPV-81 (1.9%). The youngest age group (age < 20 years) showed the highest infection rate (59.9%), and then decreased with age. As the degree of cervical lesions worsened gradually, the rate of high-risk HPV infection increased, such as 24.3% (322/1324) in the Cervicitis, 31.30% (560/1785) in the CINI, 54.1% (568/1050) in the CINII, 80.1% (693/865) in the CIN III, and 99.5% (428/430) in the cervical cancer group. These findings were significantly different from the 9.7% (155/1555) observed in the normal medical examination group (P < .05). This is the first study to demonstrate the characteristics of HPV and the association with cervical lesions in North China Plain population.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Liu L,Wang D,Dong H,Jin C,Jiang L,Song H,Jin C,Wang T,Shi C,Yang L,Wang Y

doi

10.1097/MD.0000000000017087

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

e17087

issue

37

eissn

0025-7974

issn

1536-5964

pii

00005792-201909130-00021

journal_volume

98

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • Associations Between the Periodontal Disease in Women Before Menopause and Menstrual Cycle Irregularity: The 2010-2012 Korea National Health and Nutrition Examination Survey.

    abstract::The association between menstrual cycle irregularities and system disease has been evaluated in previous studies. However, the association between periodontal disease and menstrual cycle irregularity has not been fully investigated. The study aimed to evaluate the relationship between periodontal disease and tooth los...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002791

    authors: Han K,Ko Y,Park YG,Park JB

    更新日期:2016-02-01 00:00:00

  • Effect of prediabetes on the long-term all-cause mortality of patients undergoing percutaneous coronary intervention: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:Prediabetes is an abnormal metabolic state that develops prior to the onset of diabetes with proven to common comorbid states of coronary artery disease. However, whether prediabetes worsens prognosis after percutaneous coronary intervention remains controversial. The aim of this study is to summarize previo...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000021623

    authors: Shi R,Diao KY,Shi K,Gao Y,Huang S,Guo YK,Yang ZG

    更新日期:2020-08-14 00:00:00

  • Barbed versus conventional 2-layer continuous running sutures for laparoscopic vaginal cuff closure.

    abstract::We compared results using unidirectional barbed sutures and conventional sutures for vaginal cuff closure during total laparoscopic hysterectomy (TLH).The electronic medical records and surgical videos of 170 patients who underwent TLH between January 2013 and March 2015 at Uijeong-bu St. Mary's Hospital of Catholic U...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004981

    authors: Kim JH,Byun SW,Song JY,Kim YH,Lee HJ,Park TC,Lee KH,Hur SY,Park JS,Lee SJ

    更新日期:2016-09-01 00:00:00

  • Inflammation-based Glasgow Prognostic Score in patients with acute ST-segment elevation myocardial infarction: A prospective cohort study.

    abstract::The inflammation-based Glasgow Prognostic Score (GPS), which involves C-reactive protein and serum albumin levels, has been reported to be a strong independent predictor of mortality in many cancers. This study aimed to investigate whether the GPS is associated with mortality in patients with acute ST-segment elevatio...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013615

    authors: Jia Y,Li D,Cao Y,Cheng Y,Xiao L,Gao Y,Zhang L,Zeng Z,Wan Z,Zeng R

    更新日期:2018-12-01 00:00:00

  • Intracranial solitary fibrous tumor mimicking meningioma: A case report.

    abstract:RATIONALE:Solitary fibrous tumor is a rare mesenchymal tumor. This case report describes the diagnosis and treatment of this tumor. PATIENT CONCERNS:A 31-year-old patient presented with epileptic seizure and headache 1 day prior to the visit and showed transient right limb hemiplegia for 6 hours that was resolved afte...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023504

    authors: Cheng L,Ni H,Dai Y

    更新日期:2020-12-11 00:00:00

  • Taxane-based chemotherapy and risk of breast cancer-related lymphedema: Protocol for a systematic review and meta-analysis.

    abstract:BACKGROUND:Many studies were performed to explore the correlation between taxane-based chemotherapy and the risk of breast cancer-related lymphedema (BCRL), however, with inconsistent results. Hence, the purpose of this study is to evaluate whether taxane-based chemotherapy is a risk factor for BCRL. METHODS:A compreh...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016563

    authors: Zhang Z,Zhang X,Chen S,Jiang J,Qi R,Zhang X,Xi Y,Li M,Zheng H,Hua B

    更新日期:2019-07-01 00:00:00

  • Association of chronic kidney disease with periprocedural myocardial injury after elective stent implantation: A single center prospective cohort study.

    abstract::Coronary artery disease (CAD) is the leading cause of mortality in patients with chronic kidney disease (CKD). Patients with CKD who undergo percutaneous coronary intervention (PCI) may have more ischemic events than patients without CKD. The aim of our study was to determine the incidence of periprocedural myocardial...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005381

    authors: Jerkic H,Letilovic T,Stipinovic M,Pocanic D,Catic J,Knotek M

    更新日期:2016-11-01 00:00:00

  • Prostatic stromal sarcoma: A case report and literature review.

    abstract:RATIONALE:prostatic stromal sarcoma is a very rare malignant tumor that accounts for <0.1% of prostate malignancy. PATIENT CONCERNS:: we reported a 49-year-old man presented with dysuria and hematuria, whose computed tomography examination showed an enlarged prostate gland with an irregular shape. DIAGNOSES:: the diagn...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000010495

    authors: Yang W,Liu A,Wu J,Niu M

    更新日期:2018-05-01 00:00:00

  • Analysis of factors influencing the degree of detectability on diffusion-weighted MRI and diffusion background signals in patients with invasive breast cancer.

    abstract::To determine the factors influencing the degree of detectability of lesions and diffusion background signals on magnetic resonance diffusion-weighted imaging (DWI) in invasive breast cancer.Institutional review board approval was obtained and patient consent was waived. Patients with newly diagnosed invasive ductal ca...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004086

    authors: Hahn SY,Ko ES,Han BK,Lim Y,Gu S,Ko EY

    更新日期:2016-07-01 00:00:00

  • Emergency obstetric hysterectomy for life-threatening postpartum hemorrhage: A 12-year review.

    abstract::The aim of the study was to review the operative experiences of emergency hysterectomy for life-threatening postpartum hemorrhage (PPH) performed over a 12-year period at Fujian Provincial Maternity and Children's Hospital; to examine the incidence and risk factors for emergency obstetric hysterectomy; and to evaluate...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008443

    authors: Zhang Y,Yan J,Han Q,Yang T,Cai L,Fu Y,Cai X,Guo M

    更新日期:2017-11-01 00:00:00

  • Characteristics of late-onset spondyloarthritis in Japan: A retrospective cohort study.

    abstract::Spondyloarthritis may be increasingly present in older patients as life expectancy increases. We investigated clinical differences between early-onset and late-onset spondyloarthritis in Japan.We retrospectively reviewed 114 patients consecutively diagnosed with spondyloarthritis. The clinical course of each patient w...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014431

    authors: Endo Y,Fujikawa K,Koga T,Mizokami A,Mine M,Tsukada T,Uetani M,Kawakami A

    更新日期:2019-02-01 00:00:00

  • Usefulness of multiphase computed tomography angiography in a patient with transient ischemic attack in the hyperacute phase: A case report.

    abstract:RATIONALE:Patients with transient ischemic attack (TIA) have the possibility of developing stroke in the future. To prevent recurrent TIA or future stroke, identifying the cause of TIA is important. However, about two-third of patients with TIA have negative findings on diffusion-weighted imaging (DWI).We present a cas...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009502

    authors: Lee S,Byun JS,Jung MS,Kim JM,Nam TK

    更新日期:2017-12-01 00:00:00

  • A meta-analysis: Internet mindfulness-based interventions for stress management in the general population.

    abstract:BACKGROUND:Psychological stress was an important mental health problem among the general population and warrant research to inform strategies for effective prevention. iMBIs provide a possibility to offer easily accessible, efficacious, convenient, and low-cost interventions on a wide scale. However, the efficacy of iM...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000020493

    authors: Zhang Y,Xue J,Huang Y

    更新日期:2020-07-10 00:00:00

  • Pain-induced peripheral artery tonometry scores in the control arm are impaired in patients with apical ballooning syndrome.

    abstract::Mental and physical stress is thought to play an important causative factor in apical ballooning syndrome (ABS) likely secondary to the vasomotor dysfunction. However, there are currently few data related to the impact of physical stress in this unique cardiomyopathy.A total 18 patients, including 8 females with histo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013841

    authors: Sun T,Widmer RJ,Matsuzawa Y,Lennon RJ,Park KH,Lerman LO,Lerman A

    更新日期:2019-01-01 00:00:00

  • Using an informatics education strategy to resolve the dilemma of teaching transplantation in medical institutions: Multidisciplinary medical team perspectives.

    abstract::In Taiwan, the current survival rate 1 year after transplantation exceeds 80%. However, the number of organ/tissue donors per year in Taiwan is extremely low, resulting in increased mortality. This is also true in Europe and in the United States. Recently, data from the Taiwan Organ Registry and Sharing Center showed ...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000012809

    authors: Hsieh MH,Shih FJ,Sheu SJ,Wang SS,Shih FJ

    更新日期:2018-10-01 00:00:00

  • Diagnostic Ability of FDG-PET/CT in the Detection of Malignant Pleural Effusion.

    abstract::We investigated the role of F-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) for the differential diagnosis of malignant and benign pleural effusion. We studied 36 consecutive patients with histologically proven cancer (excluding malignant mesothelioma) who underwent FDG-PET/CT...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001010

    authors: Nakajima R,Abe K,Sakai S

    更新日期:2015-07-01 00:00:00

  • Arthritis associated with Mycoplasma pneumoniae in a pediatric patient: A case report.

    abstract:INTRODUCTION:Mycoplasma pneumoniae (MP) infection in infants is usually overlooked and it might result in important complications if left untreated. MP-induced arthritis is probably the least common extrapulmonary manifestation and frequently leads to delays in the diagnosis. PATIENT CONCERNS:We report the case of a 2...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000024316

    authors: Mărginean CO,Georgescu AM,Meliţ LE

    更新日期:2021-01-15 00:00:00

  • Comparison of Direct Anterior and Lateral Approaches in Total Hip Arthroplasty: A Systematic Review and Meta-Analysis (PRISMA).

    abstract::The direct anterior approach (DAA) to total hip arthroplasty has been promoted as a minimally invasive alternative to the lateral approach, which we sought to verify by systematically reviewing and meta-analyzing the literature comparing clinical, radiographic, and surgical outcomes. Two reviewers independently search...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000002126

    authors: Yue C,Kang P,Pei F

    更新日期:2015-12-01 00:00:00

  • Lymphovenous anastomosis for the treatment of persistent congenital chylothorax in a low-birth-weight infant: A case report.

    abstract:RATIONALE:Chylothorax remains a poorly understood phenomenon, and no optimal treatment or guidelines have been established. This is the first report of treating congenital chylothorax and lymphedema in a low-birth-weight infant by lymphovenous anastomosis (LVA). PATIENT CONCERNS:We report a case of successful LVA for ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017575

    authors: Hayashida K,Yamakawa S,Shirakami E

    更新日期:2019-10-01 00:00:00

  • Prosthetic valve thrombosis - association of genetic polymorphisms of VKORC1, CYP2C9 and CYP4F2 genes.

    abstract::Prosthetic Valve Thrombosis (PVT), in spite of the advances in the valve design and the material used, remains a serious complication of mechanical cardiac valve replacement. The factors influencing the development of PVT are: thrombogenicity of the valve, hemodynamics of the transprosthetic blood flow and ineffective...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014365

    authors: Sr K,G B,Jain S,Moorthy N,Manjunath SC,Christopher R

    更新日期:2019-02-01 00:00:00

  • Distinctive patterns on CT angiography characterize acute internal carotid artery occlusion subtypes.

    abstract::Noninvasive computed tomography angiography (CTA) is widely used in acute ischemic stroke, even for diagnosing various internal carotid artery (ICA) occlusion sites, which often need cerebral digital subtraction angiography (DSA) confirmation. We evaluated whether clinical outcomes vary depending on the DSA-based occl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005722

    authors: Hong JM,Lee SE,Lee SJ,Lee JS,Demchuk AM

    更新日期:2017-02-01 00:00:00

  • Effectiveness and safety of electroacupuncture and its cotreatment with electronic moxibustion in the treatment of patients with moderate benign prostatic hyperplasia using alpha blocker: Study protocol for an assessor-blinded, randomized controlled clini

    abstract:BACKGROUND:Benign prostatic hyperplasia (BPH) is a medical condition that affects the quality of life by causing lower urinary tract symptoms (LUTS) in 40% to 70% of men aged ≥60 years. Medication treatment is primarily recommended for patients with BPH if their symptom score based on the International Prostate Symptom...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000019678

    authors: Kim HB,Kim YI,Jeon JH,Kim E,Kim JY,Kwon O,Choi YE,Yang C,Han CH

    更新日期:2020-04-01 00:00:00

  • Ultrasound for postoperative surveillance after mastectomy in patients with breast cancer: A retrospective study.

    abstract::This study aimed to evaluate the clinical usefulness of postoperative surveillance by ultrasound (PSU) in patients after breast cancer surgery.In this retrospective study, 324 patients with breast cancer after mastectomy were included between January 2006 and December 2008. The final-positive lesions (FPL) were diagno...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009244

    authors: Liu YQ,Dong JN,Meng QX,Sun P,Zhang J

    更新日期:2017-12-01 00:00:00

  • Successful treatment of colorectal liver metastasis harboring intrahepatic cholangiocarcinoma: A case report.

    abstract:RATIONALE:Colorectal liver metastasis develops in 50% of patients diagnosed with colorectal cancer, whereas concurrent intrahepatic cholangiocarcinoma (ICC) and colorectal liver metastases is extremely rare. PATIENT CONCERNS:A 72-year-old man was referred to our hospital complaining of abdominal discomfort, diarrhea, ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000013751

    authors: Cheng X,Zhao F,Chen D,Yang P,Zhong W,Xu X,Wang W

    更新日期:2018-12-01 00:00:00

  • Effect of dexmedetomidine as an adjuvant to ropivacaine for wound infiltration in patients undergoing open gastrectomy: A prospective randomized controlled trial.

    abstract:OBJECTIVES:The primary objective of this study was to investigate whether dexmedetomidine could potentiate the analgesic efficacy of ropivacaine, when added to ropivacaine for wound infiltration in patients undergoing open gastrectomy. METHODS:Fifty patients scheduled for open gastrectomy were divided into 2 equal gro...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000007950

    authors: Luan H,Zhu P,Zhang X,Tian L,Feng J,Wu Y,Yan Y,Zhao Z,Gu X

    更新日期:2017-09-01 00:00:00

  • Isolated subacute combined degeneration in late-onset cobalamin C deficiency in children: Two case reports and literature review.

    abstract:RATIONALE:Subacute combined degeneration (SCD) is a disease caused by decreased vitamin B12 intake or metabolic disorders. It is more common in the elderly and rarely seen in children. Here, we report 2 pediatric cases of SCD in late-onset cobalamin C (CblC) deficiency. PATIENT CONCERNS:The patients complained of unst...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017334

    authors: Cui J,Wang Y,Zhang H,Cui X,Wang L,Zheng H

    更新日期:2019-09-01 00:00:00

  • Reversible posterior leukoencephalopathy syndrome following apatinib for gastric cancer in an adult: A case report and a review of the literature.

    abstract:RATIONALE:Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by rapidly progressive hypertension, headache, and disturbance of consciousness. Moreover, RPLS is rarely reported after apatinib treatment. PATIENT CONCERNS:We present a case of RPLS induced by apatinib in this report. The patient had...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017787

    authors: Lv Y,Zhang Y,Zhang J,Liang N,Liu F,Liu R

    更新日期:2019-11-01 00:00:00

  • Estrogen supplementation to progesterone as luteal phase support in patients undergoing in vitro fertilization: systematic review and meta-analysis.

    abstract::Meta-analyses have found conflicting results with respect to the use of progesterone or progesterone plus estrogen as luteal phase support for in vitro fertilization (IVF) protocols involving gonadotropins and/or gonadotropin-releasing hormone analogs. The aim of the present study was to perform an updated meta-analys...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000000459

    authors: Zhang XM,Lv F,Wang P,Huang XM,Liu KF,Pan Y,Dong NJ,Ji YR,She H,Hu R

    更新日期:2015-02-01 00:00:00

  • Risk factors of the postoperative 30-day readmission of gastric cancer surgery after discharge: A PRISMA-compliant systematic review and meta-analysis.

    abstract:BACKGROUND:Readmission is a common postoperative adverse event. This study aimed to analyze potential risk factors for the incidence of postoperative 30-day readmission after discharge for gastric cancer patients with surgical treatment. METHODS:Those studies that reported the risk factors of gastric cancer patients w...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000014639

    authors: Wu WW,Zhang WH,Zhang WY,Yang L,Deng XQ,Zhu T

    更新日期:2019-03-01 00:00:00

  • Complete androgen insensitivity syndrome in a young woman with metabolic disorder and diabetes: A case report.

    abstract:RATIONALE:Androgen insensitivity syndrome (CAIS) is a rare X-linked recessive androgen receptor disorder characterized by complete resistance to the actions of androgen in an individual with 46,XY karyotype. Metabolic disorder and diabetes has been rarely reported in these patients. PATIENT CONCERNS:A 22-year-old fema...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011353

    authors: Yang P,Liu X,Gao J,Qu S,Zhang M

    更新日期:2018-08-01 00:00:00