Abstract:
RATIONALE:Sarcomatous or anaplastic carcinoma mural nodules presenting in ovarian mucinous cystic tumors are very rare. Here, we reported the ultrasonic and pathological features of 2 such cases. PATIENT CONCERNS:A 60-year-old woman presented with a complaint of lower abdominal pain. Physical examination revealed a hard, palpable mass in her right lower abdomen with mild tenderness. In addition, a 48-year-old woman presented with left abdominal pain and abdominal fullness. Physical examination revealed a palpable mass in her left lower abdomen. DIAGNOSES:The diagnosis of ovarian mucinous cystic tumor (including mucinous cystadenoma, mucinous cystadenoma of borderline malignancy, and intraepithelial carcinoma) associated with the sarcomatous mural nodule was made for the first patient. The mass of the second patient was mucinous cystic tumor (including mucinous cystadenoma, borderline malignant mucinous cystadenoma, and mucinous cystadenocarcinoma) associated with sarcoma-like mural nodules and multifocal anaplastic carcinoma. INTERVENTIONS:Both patients underwent bilateral salpingo-oophorectomy and omentectomy. In addition, appendectomy was also performed for the younger patient. OUTCOMES:Ultrasonic imaging showed huge pelvic cavity mixed masses with reticular or petaloid fluid sonolucent areas, uneven thickness separation, and multiple various mural nodules. The internal echo of the masses was complex and varied. The ultrasonic features of mural nodules were characteristic, including irregular shape, rough surface, wide basement, and nonuniform internal echogenicity. Pathological examination revealed multiple nodules with obvious atypia and mucinous cystic tumors with different malignancy. Sarcomatous or anaplastic carcinoma mural nodules showed irregular structure, significant cell atypia, and noticeable mitoses. The discovery of vascular invasion has an important role in the diagnosis of sarcomatous mural nodules. Immunohistochemical features of positive cytokeratin and negative vimentin can identify the anaplastic carcinoma component from the bizarre stromal components of the nodule. LESSONS:Ultrasonography was helpful to evaluate the preoperative diagnosis and determining the surgical approach, and pathology was indispensable to the diagnosis of these diseases.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Zhang Y,Yuan Z,Sun K,Li Pdoi
10.1097/MD.0000000000008636subject
Has Abstractpub_date
2017-11-01 00:00:00pages
e8636issue
45eissn
0025-7974issn
1536-5964pii
00005792-201711100-00096journal_volume
96pub_type
杂志文章相关文献
MEDICINE文献大全abstract::Inflammation is increasingly reported to be associated with the prognosis of patients with cancers. And the prognostic role of neutrophil-to-lymphocyte ratio (NLR) in patients with prostate cancer (PCa) remains inconsistent. Therefore, we conducted this systematic review and meta-analysis to obtain a more reliable ass...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000002544
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:Currently, the options are limited for the treatment of patients who have failed 2 lines of chemotherapy for advanced lung squamous cell carcinoma (SCC). Recently, nivolumab, a fully human IgG4 programmed death 1 immune checkpoint inhibitor antibody, was approved to treat patients with advanced stage, rela...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005077
更新日期:2016-10-01 00:00:00
abstract::To establish the comparative effectiveness of all available biologic therapy regimens for ankylosing spondylitis, we performed a systematic review and a Bayesian network meta-analysis of randomized controlled trials. PubMed, Medline, Embase, Cochrane library, and ClinicalTrials.gov were searched from the inception of ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000003060
更新日期:2016-03-01 00:00:00
abstract::Several epidemiological studies have focused on the role of nuclear factor-kappa-B inhibitor-alpha (NFKBIA) -881 A>G polymorphism in cancer susceptibility. However, the published data have led to contentious results. This study was designed to examine the association between -881 A>G polymorphism and cancer risk.Compr...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001024
更新日期:2015-08-01 00:00:00
abstract::Osteoarthritis (OA) is the most common form of arthritis in older individuals and is among the most prevalent and disabling chronic conditions worldwide.We conducted a meta-analysis to determine the efficacy and safety of celecoxib, a cyclooxygenase-2 (COX-2) inhibitor in the treatment of osteoarthritis. Studies were ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000003585
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:The inferior cerebellar peduncle (ICP) is a major neural tract in the cerebellum and is involved in coordination of movement and proprioceptive; therefore, ICP injury can be accompanied by poor coordination of movement, including ataxia. In this study, using diffusion tensor tractography (DTT), we investig...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019344
更新日期:2020-02-01 00:00:00
abstract::Calcific aortic valve disease (CAVD) is highly prevalent in our aging world and has no effective pharmaceutical treatment. Intense efforts have been made but the underlying molecular mechanisms of CAVD are still unclear.This study was designed to identify the critical genes and pathways in CAVD by bioinformatics analy...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021286
更新日期:2020-07-17 00:00:00
abstract:RATIONALE:The improvement of microneurosurgery and neuroimaging, as well as neuronavigation and neurophysiological monitoring, enables neurosurgeons to safely and accurately resect lesions on the brainstem. PATIENT CONCERNS:A 54-year-old man, with 2-year history of hypertension, presented with sudden loss of conscious...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018430
更新日期:2019-12-01 00:00:00
abstract:INTRODUCTION:We present an interesting case of Candida lusitaniae infection in a patient diagnosed with renal clear cell carcinoma.An 82-year-old male presented with worsening back pain for 1 week. Physical examination including neurologic examination was normal. A computed tomography scan of the abdomen revealed a mas...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008510
更新日期:2017-11-01 00:00:00
abstract:RATIONALE:This is the report of the first case of TAFRO syndrome (Thrombocytopenia, Anasarca, myelofibrosis, Renal dysfunction, Organomegaly) in Latin America. PATIENT CONCERNS:The patient was a 61-year-old white woman of Ashkenazi Jewish descent, who presented with a history of 8 days of nausea, vomiting, and fever; ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006271
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Recent studies have demonstrated that coronary microcirculation dysfunction (CMVD) is closely correlated with adverse clinical outcomes. In this study, quantitative stress myocardial contrast echocardiography (MCE) was used to evaluate the CMVD and to investigate its association with the prognosis of patient...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000015990
更新日期:2019-07-01 00:00:00
abstract:UNLABELLED:Cisplatin (CDDP) plus radiotherapy (RT) has been used to treat advanced laryngeal squamous cell carcinoma (LSCC) patients. Single nucleotide polymorphisms (SNPs) may be responsible for differences in chemo/radiosensitivity and side effects in those patients. We reported an advanced LSCC patient, who obtained...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000578
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Bee venom acupuncture has been used in treating patients with shoulder adhesive capsulitis, yet the effectiveness and safety remains unclear. Therefore, this systematic review will aim to assess the effectiveness and safety of bee venom acupuncture for shoulder adhesive capsulitis. METHODS:Electronic databa...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000019975
更新日期:2020-05-01 00:00:00
abstract::Abnormal serum potassium levels are associated with an increased risk of ventricular arrhythmias and mortality in patients with acute myocardial infarction (AMI). The aim of the present study was to evaluate whether different levels of serum potassium, within the normal range, are associated with worse outcomes. The p...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000003778
更新日期:2016-06-01 00:00:00
abstract::We analyzed the characteristics of patients with World Health Organization (WHO) grade III meningioma to identify factors that may predict tumor recurrence and overall survival (OS).We retrospectively reviewed the patients diagnosed with WHO grade III meningioma who were surgically treated at our institute between 200...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007385
更新日期:2017-06-01 00:00:00
abstract::This open-label, randomized phase II trial was performed to compare the efficacy and safety of nimotuzumab plus S-1 and cisplatin (NCS) versus S-1 and cisplatin (CS) alone in patients with untreated unresectable or metastatic gastric cancer in the first-line setting. Eligible participants were randomly assigned (1:1) ...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000000958
更新日期:2015-06-01 00:00:00
abstract::Mastocytosis is a heterogeneous group of diseases with a young median age at diagnosis. Usually indolent and self-limited in childhood, the disease can exhibit aggressive progression in mid-adulthood. Our objectives were to describe the characteristics of the disease when diagnosed among elderly patients, for which ra...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000003901
更新日期:2016-06-01 00:00:00
abstract:RATIONALE:Inflammatory demyelinating neuropathies such as Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and focal segmental glomerulosclerosis (FSGS) are autoimmune disorders that may have a common pathogenesis. Here, we describe 2 unique cases of FSGS, 1 with GBS and the othe...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013304
更新日期:2018-12-01 00:00:00
abstract::Prior evidence suggested that inflammation and inflammatory cytokines polymorphisms might be essential in the development of coronary heart disease (CHD) and cognitive decline. The following study investigated the associations between interleukin-35 (IL-35) polymorphisms and cognitive decline in CHD patients over a 2-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021390
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:Femoroacetabular impingement (FAI) is a common cause of hip pain and restricted range of motion in young adults and athletes. This study aims to compare clinical results and complications between patients treated for FAI who underwent either arthroscopic or open treatment. METHODS:The 7 studies were acquire...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000023364
更新日期:2020-11-20 00:00:00
abstract::Twenty-three patients with systemic lupus erythematosus (SLE) and ischemic bone necrosis are reported. All patients had received corticosteroids prior to the onset of ischemic necrosis, although one patient had received none for 13 years previously. Nineteen (83%) patients had multiple bone lesions including the femor...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-197605000-00004
更新日期:1976-05-01 00:00:00
abstract::Osteocalcin (OC) is an endocrine hormone that regulates glucose metabolism.The aim of this study was to investigate the relationship between serum OC levels and glucose metabolism after trauma.This was a retrospective study of trauma patients admitted to the Department of Emergency Medicine between October 2017 and Ap...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021901
更新日期:2020-09-04 00:00:00
abstract:RATIONALE:Acquired vertical diplopia is commonly observed in trochlear nerve palsy, often resulting from blunt head trauma or vascular problems. It is rarely caused by tumorous conditions or space occupying lesion. We report the first case of Onodi cell mucocele causing isolated trochlear nerve palsy. PATIENT CONCERNS...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015475
更新日期:2019-05-01 00:00:00
abstract::The present study compared the efficacy of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and magnetic resonance elastography (MRE) in the estimation of hepatic fibrosis stages with histopathologic correlation.This retrospective study included 104 pa...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008339
更新日期:2017-10-01 00:00:00
abstract:RATIONALE:Primary granulocytic sarcoma of the breast is a rare and poor-prognosis malignancy. Clinicians do not have sufficient knowledge of this disease and often misdirect it as other soft tissue sarcomas or inflammation. PATIENT CONCERNS:A 42-year-old female presented with a self-discovered asymptomatic growing and...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016648
更新日期:2019-08-01 00:00:00
abstract::The aim of the present study was to evaluate the clinical significance of dual radiotracer studies, C-acetate and F-fluoro-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT), for the prediction of response and recurrence after transarterial chemoembolization (TACE).This study retrospectively inc...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012311
更新日期:2018-09-01 00:00:00
abstract::Gynecologic vasculitis (GynV) has been reported as part of systemic vasculitis (SGynV) and as single-organ (isolated gynecologic) vasculitis (IGynV). In the current study, we analyzed the clinical and histologic characteristics of patients with GynV and sought to identify features that differentiate the isolated from ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0b013e3181a577f3
更新日期:2009-05-01 00:00:00
abstract::HIV-infected individuals on antiretroviral therapy (ART) are at increased risk of cardiovascular disease (CVD). Given the relationship between innate immune activation and CVD, we investigated the association of single-nucleotide polymorphisms (SNPs) in TLR4 and CD14 and carotid intima-media thickness (cIMT), a surrog...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004477
更新日期:2016-08-01 00:00:00
abstract::To investigate the feasibility of 3D arterial spin labeling (ASL) as an alternative to dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) for the qualitative and quantitative evaluation of nasopharyngeal carcinoma (NPC) perfusion.Fifty-two newly diagnosed NPC patients underwent 3D ASL and DCE-MRI scans o...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020503
更新日期:2020-05-29 00:00:00
abstract:BACKGROUND:This trial aimed to evaluate the efficacy and safety of roflumilast for treating Chinese patients with chronic obstructive pulmonary disease (COPD). METHODS:A total of 120 patients with COPD were recruited and were randomly divided into 2 groups (an intervention group and a placebo group) at a 1:1 ratio. Pa...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000009864
更新日期:2018-02-01 00:00:00