Abstract:
BACKGROUND:Acute chronic liver failure (ACLF) is the most common type of liver failure. The clinical symptoms are complex and changeable, the treatment is difficult and the fatality rate is high. It has become an urgent problem to actively seek effective treatment means and improve the clinical efficacy of ACLF patients. Studies have shown that decreased intestinal barrier function and bacterial endotoxin translocation in ACLF patients are considered to be the key causes of enterogenic endotoxemia, and traditional Chinese medicine enema has certain advantages in adjuvant treatment of this disease. However, due to the lack of evidence, there is no specific method or suggestion, so it is necessary to carry out systematic evaluation on Traditional Chinese medicine enema for ACLF and provide effective evidence for further research. METHODS:We will search the following electronic databases from their inception to July 2020: Electronic database includes PubMed, Embase, Cochrane Library, Chinese Biomedical Database WangFang, VIP medicine information, and China National Knowledge Infrastructure. Primary outcomes: survival rates, TCM syndrome score. SECONDARY OUTCOMES:liver function (alanine aminotransferase, aspartic acid amino transferase, total bilirubin), blood coagulation function (prothrombin activity), adverse events. Data will be extracted by 2 researchers independently, risk of bias of the meta-analysis will be evaluated based on the Cochrane Handbook for Systematic Reviews of Interventions. All data analysis will be conducted by data statistics software Review Manager V.5.3. and Stata V.12.0. RESULTS:The results of this study will systematically evaluate the effectiveness and safety of Traditional Chinese medicine enema for ACLF. CONCLUSION:The systematic review of this study will summarize the currently published evidence of Traditional Chinese medicine enema for ACLF to further guide its promotion and application.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Chen Y,Luo Y,Wu F,Liao N,Shi Q,Mao Ddoi
10.1097/MD.0000000000022585subject
Has Abstractpub_date
2020-10-09 00:00:00pages
e22585issue
41eissn
0025-7974issn
1536-5964pii
00005792-202010090-00057journal_volume
99pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Bariatric surgery is the recommended treatment for morbid obesity because of its rapid and sustained body weight loss effect. Nutrient deficiency-related neurological complications after bariatric surgery are often disabling. Thus, early recognition of these complications is important. Neurological complicati...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014808
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Pneumonia is the second leading cause of death in children worldwide after preterm birth and certification. Bacteria, viruses, mycoplasma, and other microorganisms are known to be the main causes of pneumonia, of which bacterial pathogenic factors account for 12.5% of cases. The invention and application of ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023217
更新日期:2020-12-11 00:00:00
abstract:OBJECTIVE:The aim of this study was to observe the counter-effect of carbon monoxide-releasing molecule-2 (CORM-2) on lipopolysaccharide (LPS)-suppressed thrombomodulin (TM) and endothelial protein C receptor (EPCR) expressions from human umbilical vein endothelial cell (HUVEC), and to reveal its mechanisms. METHODS:H...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006978
更新日期:2017-05-01 00:00:00
abstract:RATIONALE:Familial hypercholesterolemia (FH) is a common inherited cause of coronary heart disease (CHD) and premature death in an early age. Nevertheless, an ischemic heart failure (IHF) associated with FH seems to be rare, and an early diagnosis and therapy could influence the prognosis. PATIENT CONCERNS:In this 13-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012869
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:Prognosis of intrahepatic cholangiocarcinoma (ICC) remained poor despite the multitude advancement of medical care. Resection margin status is one of the few modifiable factors that a surgeon could possibly manipulate to alter the disease outcome. However, the significance of margin status and margin width...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004133
更新日期:2016-07-01 00:00:00
abstract::In this nationwide population-based cohort study, we aimed to evaluate the effects of sleep-related breathing disorders (SBD) on migraine development.Patients ages 20 years or more and diagnosed with SBD between 2000 and 2009 were evaluated as the SBD cohort (n = 3411), and compared with comparison cohort (n = 13,644)...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001506
更新日期:2015-09-01 00:00:00
abstract::Population aging has rapidly advanced throughout the world and the elderly accounting for out-of-hospital cardiac arrest (OHCA) has increased yearly.We identified all adults who experienced an out-of-hospital cardiac arrest in the All-Japan Utstein Registry of the Fire and Disaster Management Agency, a prospective, po...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002049
更新日期:2015-12-01 00:00:00
abstract::This study investigated the stress induced by well-functioning hand constraint in forced-use therapy (FUT) for children with unilateral spastic cerebral palsy (CP).Seventeen children with unilateral spastic CP (mean age 5.8 years) received FUT: 4-week unaffected upper limb immobilization with a short-arm Scotchcast an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019016
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) inhibitors are immune therapies that have shown great promise in the treatment of multiple cancers. However, immune-related adverse events of PD-1 and PD-L1 inhibitors may limit their use in non-small cell lung cancer (NSCLC). Given the rising n...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021613
更新日期:2020-08-07 00:00:00
abstract:RATIONALE:Achromobacter xylosoxidans infection is mostly reported in immunocompromised patients. Until now, it is still rarely reported in patients undergoing peritoneal dialysis. PATIENT CONCERNS:This is the 1st case of A xylosoxidans infection due to tunnel infection of a Tenckhoff catheter. DIAGNOSIS:The diagnosis...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006654
更新日期:2017-04-01 00:00:00
abstract:RATIONALE:Chronic thromboembolic pulmonary hypertension (CTEPH) is rare in children and determining the underlying etiologies is essential for treatment. Venous thromboembolism, a well-known complication in nephrotic syndrome (NS), always occurrs during the treatment in course of the disease. However, CTEPH as the firs...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012349
更新日期:2018-10-01 00:00:00
abstract:RATIONALE:Glomus tumors (GTs) are rare soft tissue neoplasms. Several treatment options have been reported for tracheal GTs including thoracotomy, bronchoscopic electrocautery, Nd: YAG laser, and cryotherapy. However, few studies have evaluated the ideal treatment for tracheal GTs. PATIENT CONCERNS:A 30-year old man w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010374
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The prognostic value of pretreatment lymphocyte to monocyte ratio (LMR) in patients with urologic tumors remains controversial. Therefore, we herein conducted a meta-analysis to systematically assess the prognostic value of LMR in patients with urologic tumors. METHODS:We comprehensively searched PubMed, EM...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000014091
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Hypertension is one of the most common chronic diseases and an increasingly public-health challenge worldwide. Previous meta-analyses evaluated the effects of azilsartan medoxomil compared to placebo or other antihypertensive drugs in patients with hypertension. However, it is still unclear which dose of azi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017050
更新日期:2019-09-01 00:00:00
abstract::To evaluate the utility of blood pressure variability (BPV) calculated using previously published and newly introduced indices using the variables falls and age as comparators.While postural hypotension has long been considered a risk factor for falls, there is currently no documented evidence on the relationship betw...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003614
更新日期:2016-05-01 00:00:00
abstract:RATIONALE:Intramuscular hemangiomas are rare benign vascular neoplasms, merely accounting for 0.8% of all hemangiomas. Moreover, there are few case reports of intramuscular hemangiomas in the upper extremities. PATIENT CONCERNS:A 24-year-old male patient presented with a 5-year history of intermittent pain of the righ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014343
更新日期:2019-02-01 00:00:00
abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019778
更新日期:2020-04-01 00:00:00
abstract::Olfactory outcomes as well as oronasal postoperative complications of transsphenoidal pituitary surgery have not been well studied. The objective of this study was to investigate nasal symptoms including olfactory function as well as quality of life following transsphenoidal pituitary surgery. The study is designed as...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000465
更新日期:2015-01-01 00:00:00
abstract::This study aimed to assess the efficacy of allograft in 2-level anterior cervical discectomy and fusion (ACDF) with plate fixation by comparing its clinical and radiological outcomes to those of autograft.Thirty five patients with femur cortical allografts and 32 patients with tricortical iliac autografts were evaluat...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016621
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Lung cancer is one of the most common malignant tumors, and non-small cell lung cancer (NSCLC) accounts for about 85% of lung cancer diagnosed. For patients with resectable early stage non-small cell lung cancer, routine postoperative adjuvant therapy can significantly prolong overall patient survival and re...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016468
更新日期:2019-07-01 00:00:00
abstract::Few case series provide a current, comprehensive, and detailed description of splenic infarction (SI), an uncommon condition.Retrospective chart review complemented by imaging evaluation and patient follow-up.All adult patients with a confirmed diagnosis of acute SI discharged over 10 years from a single academic cent...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001363
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Silicone sheet is commonly used for scar management but hard to apply to irregular surfaces or mobile areas, and difficult to conceal. On the contrary, silicone gel is easy to apply and nearly unnoticeable. Therefore, we conducted this study to compare their effectiveness. METHODS:Patients undergoing horizo...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000011767
更新日期:2018-08-01 00:00:00
abstract::Hypertension continues to be an important public health concern because of its associated morbidity, mortality, and economic impact on society. The aims of this study are to compare the secular changes in age-stratified hypertension prevalence, incidence, co-morbidity, and 3 years of cardiovascular outcome in Taiwan i...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022437
更新日期:2020-09-25 00:00:00
abstract::To review the reported evidence on the therapeutic management of IgG4-related disease (IgG4-RD) in clinical practice.A systematic search of the literature was conducted. The primary outcome measured was the rate of efficacy of first-line therapeutic approaches. Secondary outcomes measured included the rate of disease ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000004002
更新日期:2016-06-01 00:00:00
abstract::Several points can be made from analysis of the published cases of cutaneous mycobacteriosis and those in our series: 1) mycobacterial cutaneous infections are probably more common than is reported-we collected 34 cases over a 10-year period; 2) most patients with cutaneous infections caused by nontuberculous mycobact...
journal_title:Medicine
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002325.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000483155.73927.6c
更新日期:2016-05-06 00:00:00
abstract::To assess the effects of the gatekeeper policy implemented in Shenzhen, China, in conjunction with a labor health insurance program, on channeling patients toward community health centers (CHCs).Eight thousand patients who visited 8 CHCs in Shenzhen were surveyed between May 1, 2013 and July 28, 2013. Half of the pati...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007719
更新日期:2017-09-01 00:00:00
abstract::The inflammation-based Glasgow Prognostic Score (GPS), which involves C-reactive protein and serum albumin levels, has been reported to be a strong independent predictor of mortality in many cancers. This study aimed to investigate whether the GPS is associated with mortality in patients with acute ST-segment elevatio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013615
更新日期:2018-12-01 00:00:00
abstract::Metabolic syndrome (MetS) is a major public health concern. Efficient screening requires criteria that are economical, easily accessible, and applicable for all populations. We aimed to compare the discriminating ability of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) for the diagn...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008192
更新日期:2017-09-01 00:00:00
abstract:RATIONALE:Subcutaneous implantable electrocardiographs are highly effective in detecting covert atrial fibrillation (AF) in cryptogenic stroke. However, these invasive devices are not indicated for all cryptogenic stroke patients, and noninvasive improvements over conventional Holter-type ambulatory electrocardiography...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005995
更新日期:2017-02-01 00:00:00