Role of injection laryngoplasty in preventing post-stroke aspiration pneumonia, case series report.


INTRODUCTION:Injection laryngoplasty is a common procedure for patients with vocal fold dysfunction, but the literature on its benefits has been mainly focused on those related to structural lesions or laryngeal nerve involvement. Stroke patients may be at increased risk of aspiration due to insufficient vocal fold motion. However, how injection laryngoplasty can be of benefit in stroke patients has not been reported yet. PATIENT CONCERNS:Six chronic stroke patients with long-standing swallowing difficulties and who showed severe aspiration despite long-term swallowing rehabilitation. DIAGNOSIS:Laryngoscope evaluation revealed insufficient glottic closure as the cause of aspiration. INTERVENTIONS:Injection laryngoplasty was done per-orally under local anaesthesia with calcium hydroxylapatite (Radiesse Voice, 1-1.5 mL) in an office setting. Respiratory pressures and peak cough flows were assessed at baseline and at 2 weeks follow-up. OUTCOMES:At 2 weeks, the mean peak cough flow (Δ = +95.09 L/min) increased significantly after the procedure. The maximal expiratory (Δ = +18.40 cm H2O) and inspiratory (Δ = +20.20 cm H2O) pressures also improved, indicating that injection laryngoplasty was effective in augmenting respiratory and cough parameters. All cases showed improvement in the Functional Oral Intake Scale (Δ = +4). Feeding tubes were successfully removed. CONCLUSION:Injection laryngoplasty proved to be both successful and safe in improving glottic closure with immediate results in those who had failed to show a positive response after long-term swallowing rehabilitation. The positive and dramatic clinical outcomes were observed through changes in the coughing force. Our case series support the use of injection larygnoplasty as a powerful adjunctive treatment method to prevent aspiration pneumonia in post-stroke patients with vocal fold insufficiency. Pre- and post-injection peak cough flow changes may reflect improvement in glottic closure and indicate the safety of swallowing with reduced risk of aspiration.


Medicine (Baltimore)




Han YJ,Jang YJ,Park GY,Joo YH,Im S




Has Abstract


2020-02-01 00:00:00
















  • The Incidence of Deep Vein Thrombosis in Asian Patients With Chronic Obstructive Pulmonary Disease.

    abstract::Most studies have focused on the prevalence of deep vein thrombosis (DVT) and pulmonary embolism in patients with chronic obstructive pulmonary disease (COPD) and acute exacerbation in Caucasian populations. DVT is supposedly less likely to occur among Asians than Caucasians, and the primary purpose of this study was ...


    pub_type: 杂志文章


    authors: Chen CY,Liao KM

    更新日期:2015-11-01 00:00:00

  • Erratum: A simple blind placement of the left-sided double-lumen tubes: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000005376.]. ...


    pub_type: 已发布勘误



    更新日期:2017-02-17 00:00:00

  • Folic Acid Intake and Neural Tube Defects: Two Egyptian Centers Experience.

    abstract::Neural tube defects (NTDs) are a group of congenital malformations with worldwide distribution and complex etiopathogenesis. Folic acid plays a pivotal role in their prevention. We aimed to identify the protective effect of folic acid intake against NTDs and its dependence on different socioeconomic and environmental ...


    pub_type: 杂志文章,多中心研究


    authors: El-Shabrawi MH,Kamal NM,Elhusseini MA,Hussein L,Abdallah EAA,Ali YZA,Azab AA,Salama MA,Kassab M,Krawinkel M

    更新日期:2015-09-01 00:00:00

  • Treatment of chronic obstructive pulmonary disease in patients with different fractional exhaled nitric oxide levels.

    abstract::Some patients with chronic obstructive pulmonary disease (COPD) have eosinophilic inflammation which may be evaluated via the measurement of fractional exhaled nitric oxide (FeNO) like asthma. The aim of this prospective study was to assess whether FeNO levels can be used to identify patients with COPD with eosinophil...


    pub_type: 杂志文章


    authors: Wu YK,Su WL,Huang CY,Yang MC,Chen SY,Lan CC

    更新日期:2018-11-01 00:00:00

  • Infective Endocarditis and Cancer Risk: A Population-Based Cohort Study.

    abstract::This study investigated the possible relationship between endocarditis and overall and individual cancer risk among study participants in Taiwan.We used data from the National Health Insurance program of Taiwan to conduct a population-based, observational, and retrospective cohort study. The case group consisted of 14...


    pub_type: 杂志文章


    authors: Sun LM,Wu JN,Lin CL,Day JD,Liang JA,Liou LR,Kao CH

    更新日期:2016-03-01 00:00:00

  • Placebo-Controlled Trials in Surgery: A Systematic Review and Meta-Analysis.

    abstract::This systematic review was performed to investigate the ethical justification, methodological quality, validity and safety of placebo controls in randomized placebo-controlled surgical trials.Central, MEDLINE, and EMBASE were systematically searched to identify randomized controlled trials comparing a surgical procedu...


    pub_type: 杂志文章,meta分析,评审


    authors: Probst P,Grummich K,Harnoss JC,Hüttner FJ,Jensen K,Braun S,Kieser M,Ulrich A,Büchler MW,Diener MK

    更新日期:2016-04-01 00:00:00

  • Accuracy of Raman spectroscopy for differentiating skin cancer from normal tissue.

    abstract:BACKGROUND:Raman spectroscopy could be applied to distinguish tumor from normal tissues. This meta-analysis assessed the accuracy of Raman spectroscopy in differentiating skin cancer from normal tissue. METHODS:PubMed, Embase, Cochrane Library, and CNKI were searched to identify suitable studies before Februray 4th, 2...


    pub_type: 杂志文章,meta分析,评审


    authors: Zhang J,Fan Y,Song Y,Xu J

    更新日期:2018-08-01 00:00:00

  • A Case Report of Renal Sympathetic Denervation for the Treatment of Polymorphic Ventricular Premature Complexes: Expanding Horizons.

    abstract::Premature ventricular complexes are very common, appearing most frequently in patients with hypertension, obesity, sleep apnea, and structural heart disease. Sympathetic hyperactivity plays a critical role in the development, maintenance, and aggravation of ventricular arrhythmias. Recently, Armaganijan et al reported...


    pub_type: 杂志文章


    authors: Kiuchi MG,Vitorio FP,Silva GRD,Paz LMR,Souto GLL

    更新日期:2015-12-01 00:00:00

  • Low-dose methotrexate-induced vulvar edema: A case report.

    abstract:RATIONALE:Methotrexate (MTX) is an antimetabolite of folic acid, which is used for management of ectopic pregnancy. MTX-related toxicity may include cutaneous mucosal damage, bone marrow suppression, gastrointestinal disorders (gastritis, diarrhea, hematitis), liver and kidney function damage, pulmonary toxicity, cardi...


    pub_type: 杂志文章,评审


    authors: Jia G,Chai W,He Z,Liu X,Wen Y,Cui L,Gong F

    更新日期:2019-08-01 00:00:00

  • The association between sleep duration and prostate cancer: A systematic review and meta-analysis.

    abstract::The association between sleep duration and prostate cancer (PCa) risk is still unclear. We performed a systematic review and meta-analysis to explore if sleep duration is associated with PCa in men.A comprehensive literature search was conducted in November 2019 based on the Pubmed, Embase, and Cochrane databases. Aft...


    pub_type: 杂志文章,meta分析


    authors: Liu R,Wu S,Zhang B,Guo M,Zhang Y

    更新日期:2020-07-10 00:00:00

  • An Attempt to Evaluate Selected Aspects of "Bone-Fat Axis" Function in Healthy Individuals and Patients With Pancreatic Cancer.

    abstract::Recently, much attention has been paid to a potential biochemical cross-talk between the metabolism of the adipose tissue (AT) and bone (marrow), termed "bone-fat axis." We hypothesized that selected substances, participating in this "dialog," are associated with body mass and peripheral trafficking of bone marrow-der...


    pub_type: 杂志文章


    authors: Blogowski W,Dolegowska K,Deskur A,Dolegowska B,Starzyńska T

    更新日期:2015-08-01 00:00:00

  • Hypertension and selected indicators of health assessment in a population of 19-year-old men subject to military qualifications.

    abstract::Assessment the prevalence of hypertension and its relation to selected indicators of health status and performance, including classification of BMI, obesity classifications, and body structure in a large test group of 19-year-old men.The study was observational-retrospective, and included a group of 17,282 men, aged 1...


    pub_type: 杂志文章


    authors: Chmiel Z,Żal M,Więch P,Bazaliński D,Sałacińska I,Bartusik-Aebisher D,Binkowska-Bury M

    更新日期:2020-05-29 00:00:00

  • Efficacy and Safety of Zoledronic Acid and Pamidronate Disodium in the Treatment of Malignant Skeletal Metastasis: A Meta-Analysis.

    abstract::Solid tumors frequently metastasize to bone. Two bisphosphonates have been investigated for bone metastases including pamidronate disodium and zoledronic acid.By searching the PubMed, Embase, Wanfang, and China National Knowledge Infrastructure (CNKI) databases, we conducted a meta-analysis to determine the efficacy a...


    pub_type: 杂志文章,meta分析


    authors: Yang L,Du S

    更新日期:2015-10-01 00:00:00

  • Creatine kinase in the U.S. population: Impact of demographics, comorbidities, and body composition on the normal range.

    abstract:BACKGROUND:Creatine kinase (CK) values are a critical part of the workup of suspected myopathies and are often assessed in patients that develop myalgia on statin therapy. CK elevations may influence the initiation and cessation of statin treatment, and incidentally discovered CK elevation may lead to further testing. ...


    pub_type: 杂志文章


    authors: George MD,McGill NK,Baker JF

    更新日期:2016-08-01 00:00:00

  • Association of Bisphenol A Exposure With Hypertension and Early Macrovascular Diseases in Chinese Adults: A Cross-Sectional Study.

    abstract::Bisphenol A (BPA) is an environmental endocrine disruptor that has been associated with cardiovascular outcomes in previous observational studies. We aimed to examine the relationships of urinary BPA levels with hypertension and early macrovascular diseases.This is a cross-sectional study. From June through August 200...


    pub_type: 杂志文章


    authors: Wang T,Xu M,Xu Y,Lu J,Li M,Chen Y,Wang W,Lai S,Bi Y,Ning G

    更新日期:2015-10-01 00:00:00

  • Erratum: Polysplenia Syndrome With Splenic and Skeletal Muscle Metastases From Thyroid Carcinoma Evaluated by FDG PET/CT: Case Report and Literature Review: A CARE-Compliant Article: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000002532.]. ...


    pub_type: 已发布勘误



    更新日期:2016-08-26 00:00:00

  • Expanding pancreas donor pool by evaluation of unallocated organs after brain death: Study protocol clinical trial (SPIRIT Compliant).

    abstract:BACKGROUND:Pancreas graft quality directly affects morbidity and mortality rates after pancreas transplantation (PTx). The criteria for pancreas graft allocation are restricted, which has decreased the number of available organs. Suitable pancreatic allografts are selected based on donor demographics, medical history, ...


    pub_type: 杂志文章,多中心研究


    authors: Kulu Y,Khajeh E,Ghamarnejad O,Nikdad M,Sabagh M,Ali-Hasan-Al-Saegh S,Nadalin S,Quante M,Pisarski P,Jänigen B,Reißfelder C,Mieth M,Morath C,Goeppert B,Schirmacher P,Strobel O,Hackert T,Zeier M,Springel R,Schleicher C

    更新日期:2020-03-01 00:00:00

  • Endoscopic ultrasound without tissue acquisition has poor accuracy for diagnosing gastric subepithelial tumors.

    abstract::Incidental gastric subepithelial tumor (SET) is frequently found during endoscopy. Although endoscopic ultrasonography (EUS) can provide useful information, its diagnostic accuracy varies. Most of the potentially malignant tumors observed on EUS are hypoechoic lesions. Therefore, we aimed to investigate the diagnostic...


    pub_type: 杂志文章


    authors: Lim TW,Choi CW,Kang DH,Kim HW,Park SB,Kim SJ

    更新日期:2016-11-01 00:00:00

  • Application of enamel matrix derivative and deproteinized bovine bone for the treatment of peri-implantitis after decontamination with an ultrasonic scaler: A case report.

    abstract:RATIONALE:The purpose of this report is to present a case of peri-implantitis with successful regeneration. The surface of the affected dental implant was decontaminated with an ultrasonic scaler and treated with bovine-derived hydroxyapatite and enamel matrix derivative. PATIENT CONCERNS:A 52-year-old male was referr...


    pub_type: 杂志文章


    authors: Park JB

    更新日期:2018-11-01 00:00:00

  • Effect of prediabetes on the long-term all-cause mortality of patients undergoing percutaneous coronary intervention: A protocol for systematic review and meta analysis.

    abstract:BACKGROUND:Prediabetes is an abnormal metabolic state that develops prior to the onset of diabetes with proven to common comorbid states of coronary artery disease. However, whether prediabetes worsens prognosis after percutaneous coronary intervention remains controversial. The aim of this study is to summarize previo...


    pub_type: 杂志文章,meta分析


    authors: Shi R,Diao KY,Shi K,Gao Y,Huang S,Guo YK,Yang ZG

    更新日期:2020-08-14 00:00:00

  • Comparison between open reduction and internal fixation and minimally invasive surgery in management of Sanders type II calcaneal fracture: A randomized controlled trial protocol.

    abstract:BACKGROUND:The minimally invasive surgery possesses an essential and growing function in treating the calcaneal fractures, but the related literature on this topic is limited. For our study, the main purpose was to compare the early prognosis of a group of the patients with Sanders type II fracture of calcaneus treated...


    pub_type: 杂志文章


    authors: Xue D,Lou B,Tan R,Yu H

    更新日期:2020-12-18 00:00:00

  • Intraoperative blood salvage may shorten the lifespan of red blood cells within 3 days postoperatively: A pilot study.

    abstract:BACKGROUND:Intraoperative blood salvage (IBS) recovers most lost blood, and is widely used in the clinic. It is unclear why IBS does not reduce long-term postoperative requirements for red blood cells (RBCs), and 1 possibility is that IBS affects RBC lifespan. METHODS:Prospectively enrolled patients who underwent spin...


    pub_type: 杂志文章


    authors: Liao XY,Zuo SS,Meng WT,Zhang J,Huang Q,Gou DM

    更新日期:2017-09-01 00:00:00

  • Aspergillus tracheobronchitis: report of 8 cases and review of the literature.

    abstract::Aspergillus tracheobronchitis (AT) is an infrequent but severe form of invasive pulmonary aspergillosis in which the fungal infection is entirely or predominantly confined to the tracheobronchial tree. We reviewed 8 cases of AT diagnosed in our tertiary care center during an 18-year period, as well as 148 cases previo...


    pub_type: 杂志文章,评审


    authors: Fernández-Ruiz M,Silva JT,San-Juan R,de Dios B,García-Luján R,López-Medrano F,Lizasoain M,Aguado JM

    更新日期:2012-09-01 00:00:00

  • Patient outcomes following surgical management of multinodular goiter: Does multinodularity increase the risk of thyroid malignancy?

    abstract:BACKGROUND:the difference in the risk of thyroid malignancy for patients with multinodular goiter (MNG) and solitary nodular goiter (SNG) remains controversial. Although total thyroidectomy (TT) is the current preferred surgical option for MNG, permanent hypothyroidism in these patients may be a concern. Therefore, we ...


    pub_type: 杂志文章


    authors: Lin YS,Wu HY,Yu MC,Hsu CC,Chao TC

    更新日期:2016-07-01 00:00:00

  • The prognostic value of left ventricular systolic function and cardiac biomarkers in pediatric severe sepsis.

    abstract::Echocardiography and cardiac biomarkers, such as cardiac troponin I (cTnI) and N-terminal pro-B-type natriuretic peptide (NT-pro BNP) are useful tools to evaluate cardiac dysfunction. Left ventricular systolic dysfunction (LVSD) is common in pediatric severe sepsis. The aim of this study is to evaluate the prognostic ...


    pub_type: 杂志文章


    authors: Li J,Ning B,Wang Y,Li B,Qian J,Ren H,Zhang J,Hu X

    更新日期:2019-03-01 00:00:00

  • Nasopharyngeal carcinoma perfusion MRI: Comparison of arterial spin labeling and dynamic contrast-enhanced MRI.

    abstract::To investigate the feasibility of 3D arterial spin labeling (ASL) as an alternative to dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) for the qualitative and quantitative evaluation of nasopharyngeal carcinoma (NPC) perfusion.Fifty-two newly diagnosed NPC patients underwent 3D ASL and DCE-MRI scans o...


    pub_type: 杂志文章


    authors: Xiao B,Wang P,Zhao Y,Liu Y,Ye Z

    更新日期:2020-05-29 00:00:00

  • Ectoparasitism and vector-borne diseases in 930 homeless people from Marseilles.

    abstract::Homeless people are particularly exposed to ectoparasites, but their exposure to arthropod-borne diseases has not been evaluated systematically. A medical team of 27 persons (7 nurses, 6 infectious disease residents or fellows, 2 dermatologists, and 12 infectious disease specialists) visited the 2 shelters in Marseill...


    pub_type: 杂志文章


    authors: Brouqui P,Stein A,Dupont HT,Gallian P,Badiaga S,Rolain JM,Mege JL,La Scola B,Berbis P,Raoult D

    更新日期:2005-01-01 00:00:00

  • Application of stepper in cardiopulmonary exercise test for patients with hemiplegia.

    abstract::A method to perform exercise testing for patients with hemiplegia is unavailable though over half of them have cardio-pulmonary disorders. We aimed to assess the reliability and validity of using a stepper in cardiopulmonary exercise testing (CPET) in this population.14 stroke patients with hemiplegia who failed to ri...


    pub_type: 杂志文章


    authors: Huang SC,Hsu CC,Fu TC,Chen CP,Liao MF,Hsu YH,Wang JS

    更新日期:2020-07-10 00:00:00

  • Estrogen supplementation to progesterone as luteal phase support in patients undergoing in vitro fertilization: systematic review and meta-analysis.

    abstract::Meta-analyses have found conflicting results with respect to the use of progesterone or progesterone plus estrogen as luteal phase support for in vitro fertilization (IVF) protocols involving gonadotropins and/or gonadotropin-releasing hormone analogs. The aim of the present study was to perform an updated meta-analys...


    pub_type: 杂志文章,meta分析,评审


    authors: Zhang XM,Lv F,Wang P,Huang XM,Liu KF,Pan Y,Dong NJ,Ji YR,She H,Hu R

    更新日期:2015-02-01 00:00:00

  • Comparison of efficacy and safety of combination therapy with statins and omega-3 fatty acids versus statin monotherapy in patients with dyslipidemia: A systematic review and meta-analysis.

    abstract:OBJECTIVE:Dyslipidemia is a major risk factor for the development of cardiovascular disease. Both statins and omega-3 fatty acids demonstrate beneficial effects on lipid concentrations. The goal was to evaluate the safety and efficacy of combination therapy with statins and omega-3 fatty acids. METHODS:We performed a ...


    pub_type: 杂志文章,meta分析


    authors: Choi HD,Chae SM

    更新日期:2018-12-01 00:00:00