Biochemical changes induced by Coxsackie B4 virus in short-term culture of mouse pancreatic islets.

abstract：:The extracts of Paulownia tomentosa (P. tomentosa) exhibit multiple pharmacological activities. In the present study, P. tomentosa flower polysaccharides (PTFP) were extracted by water decoction and ethanol precipitation, and the immunologic modulations of PTFP against Newcastle disease (ND) vaccine was investigated i...

journal_title：Bioscience reports

authors： Yang H,Zhang P,Xu X,Chen X,Liu Q,Jiang C

更新日期：2019-05-03 00:00:00

abstract：:Chemical transformations, like osmotic translocations, are transport processes when looked at in detail. In chemiosmotic systems, the pathways of specific ligand conduction are spatially orientated through osmoenzymes and porters in which the actions of chemical group, electron and solute transfer occur as vectorial (...

journal_title：Bioscience reports

authors： Mitchell PD

更新日期：2004-08-01 00:00:00

abstract：:Having a better grasp of the molecular mechanisms underlying carcinogenesis and progression in osteosarcoma would be helpful to find novel therapeutic targets. Different types of cancers have presented abnormal expression of miRNA-101 (miR-101). Nevertheless, we still could not figure out what expression of miR-101 in...

journal_title：Bioscience reports

authors： Lin H,Zheng X,Lu T,Gu Y,Zheng C,Yan H

更新日期：2019-02-08 00:00:00

abstract：OBJECTIVE:The role of lncRNAs in tumor has been widely concerned. The present study took HAS2-AS1 (the antisense RNA 1 of HAS2) as a starting point to explore its expression in glioma and its role in the process of migration and invasion, providing a strong theoretical basis for mining potential therapeutic targets of ...

journal_title：Bioscience reports

authors： Wang J,Gu J,You A,Li J,Zhang Y,Rao G,Ge X,Zhang K,Li J,Liu X,Wang Q,Lin T,Cheng L,Zhu M,Wu X,Wang D

更新日期：2020-08-28 00:00:00

abstract：:This review covers the recent progress in the elucidation of the structure of photosystem II (PSII). Because much of the structural information for this membrane protein complex has been revealed by electron microscopy (EM), the review will also consider the specific technical and interpretation problems that arise wi...

journal_title：Bioscience reports

authors： Nicholson WV,Ford RC,Holzenburg A

更新日期：1996-04-01 00:00:00

abstract：:Hospital-acquired infections are common in burn patients and are the major contributors of morbidity and mortality. Bacterial infections such as Staphylococcus aureus (S. aureus) and Acinetobacter baumannii (A. baumannii) are difficult to treat due to their biofilm formation and rapidly acquiring resistance to antibio...

journal_title：Bioscience reports

authors： Khan A,Xu M,Wang T,You C,Wang X,Ren H,Zhou H,Khan A,Han C,Li P

更新日期：2019-06-18 00:00:00

abstract：:Cardiac hypertrophy is a compensatory response to stress or stimuli, which results in arrhythmia and heart failure. Although multiple molecular mechanisms have been identified, cardiac hypertrophy is still difficult to treat. Pyroptosis is a caspase-1 dependent pro-inflammatory programmed cell death. Caspase-1 is invo...

journal_title：Bioscience reports

authors： Bai Y,Sun X,Chu Q,Li A,Qin Y,Li Y,Yue E,Wang H,Li G,Zahra SM,Dong C,Jiang Y

更新日期：2018-02-12 00:00:00

abstract：:Increasing studies are indicating that long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is associated with the prognosis of cancer patients. However, the results have been disputed. Therefore, we aimed to further explore the prognostic value and clinical significance of XIST in various types of cance...

journal_title：Bioscience reports

authors： Liu X,Ming X,Jing W,Luo P,Li N,Zhu M,Yu M,Liang C,Tu J

更新日期：2018-06-21 00:00:00

abstract：:The role of the topoisomerase enzyme in DNA recombination was investigated by extracting chromosomal deoxyribonucleoproteins from a variety of cultured mammalian cells and assaying for the formation of recombinant DNA structures. Although each of the crude deoxyribonucleoprotein preparations contained topoisomerase ac...

journal_title：Bioscience reports

authors： Hamelin C,Alain R,Houde D,Berthiaume L

更新日期：1982-07-01 00:00:00

abstract：:Dendritic cells (DCs) present exogenous antigens on major histocompatibility complex (MHC) class I molecules, thereby activating CD8+ T cells, contributing to tumor elimination through a mechanism known as antigen cross-presentation. A variety of factors such as maturation state of DCs, co-stimulatory signals, T-cell ...

journal_title：Bioscience reports

authors： Warrier VU,Makandar AI,Garg M,Sethi G,Kant R,Pal JK,Yuba E,Gupta RK

更新日期：2019-10-30 00:00:00

abstract：:Secretion of high molecular weight (HMW) adiponectin is dependent on post-translational modification (PTM) of conserved lysines in the collagenous domain. The present study aims to characterize the enzymes responsible for the PTM of conserved lysines which leads to HMW adiponectin secretion, and to define its signific...

journal_title：Bioscience reports

authors： Webster JA,Yang Z,Kim YH,Loo D,Mosa RM,Li H,Chen C

更新日期：2017-05-17 00:00:00

abstract：:To observe the effect of gene expression and tumorigenicity in hybrid cells of human embryonic stem cells (hESCs) and ovarian cancer cells in vitro and in vivo using a mouse model, and to determine its feasibility in reprogramming tumour cells growth and apoptosis, for a potential exploration of the role of hESCs and ...

journal_title：Bioscience reports

authors： He K,Qu H,Xu LN,Gao J,Cheng FY,Xiang P,Zhou CQ

更新日期：2016-09-16 00:00:00

abstract：:Fasudil is a derivative of 5-isoquinoline sulfonamide, which is a Rho kinase inhibitor, a wide range of pharmacological effects. Fasudil has been shown to attenuate kidney injury caused by certain substances. In the present study, metabolomic analysis of mouse kidney tissues ultra-performance liquid chromatography/qua...

journal_title：Bioscience reports

authors： Xia D,Lai X,Wu K,Zhou P,Li L,Guo Z,Xu S

更新日期：2019-11-29 00:00:00

abstract：:Neural stem cells (NSCs) transplantation is one of the most promising strategies for the treatment of CA-induced brain damage. The transplanted NSCs could differentiate into new neuron and replace the damaged one. However, the poor survival of NSCs in severe hypoxic condition is the limiting step to make the best use ...

journal_title：Bioscience reports

authors： Li F,Wei H,Li H,Li X,Hu C,Zhang J,Deng Y,Liao X

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Breast cancer (BC) is the most common malignancy among females worldwide. The tumor microenvironment usually prevents effective lymphocyte activation and infiltration, and suppresses infiltrating effector cells, leading to a failure of the host to reject the tumor. CC chemokines play a significant role in in...

journal_title：Bioscience reports

authors： Chen B,Zhang S,Li Q,Wu S,He H,Huang J

更新日期：2020-11-27 00:00:00

abstract：:Although membrane fusion occurs ubiquitously and continuously in all eukaroytic cells, little is known about the mechanism that governs lipid bilayer fusion associated with any intracellular fusion reactions. Recent studies of the fusion of enveloped viruses with host cell membranes have helped to define the fusion pr...

journal_title：Bioscience reports

authors： Martin I,Ruysschaert JM

更新日期：2000-12-01 00:00:00

abstract：:We aimed to confirm the role of miR-1296-5p in gastric cancer and to identify its target genes. The expression of miR-1296-5p was measured in gastric cancer tissues and cell lines. The function of miR-1296-5p was examined by the overexpression and inhibition of its expression in typical gastric cell lines as well as S...

journal_title：Bioscience reports

authors： Jia Y,Zhao LM,Bai HY,Zhang C,Dai SL,Lv HL,Shan BE

更新日期：2019-01-08 00:00:00

abstract：:Objectives In the present study, we examined available articles from online databases to comprehensively investigate the effect of the XPC (xeroderma pigmentosum complementation group C) rs2228000 polymorphism on the risk of different types of clinical cancer. Methods We conducted a group of overall and subgroup pooli...

journal_title：Bioscience reports

authors： Dai Y,Song Z,Zhang J,Gao W

更新日期：2019-12-20 00:00:00

abstract：:Whether they are small enough to wriggle through the current-carrying part of an ionic channel or big enough to be kept outside and thus able to exert an osmotic stress on the channel space, polymers interact with channels in several instructive ways. The osmotic stress of excluded polymers allows one to measure the n...

journal_title：Bioscience reports

authors： Parsegian VA,Bezrukov SM,Vodyanoy I

更新日期：1995-12-01 00:00:00

abstract：:In recent decades, many genome-wide association studies on insomnia have reported numerous genes harboring multiple risk variants. Nevertheless, the molecular functions of these risk variants conveying risk to insomnia are still ill-studied. In the present study, we integrated GWAS summary statistics (N=386,533) with ...

journal_title：Bioscience reports

authors： Sun H,Zhang J,Ma Y,Liu J

更新日期：2020-09-30 00:00:00

abstract：:Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents. ...

journal_title：Bioscience reports

authors： Bouillaud F,Combes-George M,Ricquier D

更新日期：1983-08-01 00:00:00

abstract：:31P NMR studies on microorganisms have been carried out with the cells embedded in agarose gel. The novel use of the gel for the NMR studies has advantages over the usual liquid suspensions in terms of improved reproducibility of data and cell viability, with no net loss of spectral quality. Polyphosphate formation in...

journal_title：Bioscience reports

authors： Jacobson L,Cohen JS

更新日期：1981-02-01 00:00:00

abstract：:Native bovine parathyroid hormone (bPTH) was found to be readily cleaved with human leukocyte elastase to yield the fragments bPTH(1-41) and bPTH(42-84). These were then isolated by reverse-phase HPLC and characterised by gas-phase sequencing and amino acid analysis. The biological activities of these fragments were a...

journal_title：Bioscience reports

authors： Barling PM,Lowe C

更新日期：1987-01-01 00:00:00

abstract：:In order to gain information on the metabolism of dolichol, the rates of excretion of dolichol and dolichyl phosphate were determined in rats maintained on a dolichol-free diet for 10 days. Analysis of fecal samples collected every 48 h yielded mean output values of 9.0 +/- 1.4 and 20.7 +/- 3.0 micrograms/rat/day of d...

journal_title：Bioscience reports

authors： Connelly LW,Keller RK

更新日期：1984-09-01 00:00:00

abstract：:An antibody was raised to the synthetic pentapeptide pGluHisProGlyLys which, in radioimmunoassay (RIA), could detect the pentapeptide at a level of 10 fmole per tube and exhibited less than 0.5 per cent cross reactivity with a series of related peptides. The RIA was used to demonstrate the presence of C-terminally ext...

journal_title：Bioscience reports

authors： Cockle SM,Smyth DG

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Polycystic ovarian syndrome (PCOS) is a kind of common gynecological endocrine disorder. And the mutations of melatonin receptor (MTNR) genes are related to the occurrence of PCOS. But previous researches have shown opposite results. So, the object of our systematic review and meta-analysis is to investigate...

journal_title：Bioscience reports

authors： Yi S,Xu J,Shi H,Li W,Li Q,Sun YP

更新日期：2020-06-26 00:00:00

abstract：:Thrombospondins (TSPs) are evolutionarily-conserved, secreted glycoproteins that interact with cell surfaces and extracellular matrix (ECM) and have complex roles in cell interactions. Unlike the structural components of the ECM that form networks or fibrils, TSPs are deposited into ECM as arrays of nanoscale puncta. ...

journal_title：Bioscience reports

authors： Hellewell AL,Gong X,Schärich K,Christofidou ED,Adams JC

更新日期：2015-05-20 00:00:00

abstract：:Fatty-acid synthesis has been measured in vivo with 3H2O in cafeteria-fed rats exhibiting diet-induced thermogenesis. Synthesis was decreased in brown adipose tissue, the liver, white adipose tissue, and the carcass of the cafeteria-fed animals compared to rats fed the normal stock diet. Whole-body synthesis was also ...

journal_title：Bioscience reports

authors： Rothwell NJ,Stock MJ,Trayhurn P

更新日期：1983-03-01 00:00:00

abstract：:In India, Sorghum plant allergenicity was reported to be approximately 54.9%. Sorghum bicolor Polcalcin (Sorb PC) was identified as the panallergen but the specificity of this allergen is yet to be characterized. The present study was aimed to characterize the antigenic determinants of Sorb PC that are responsible for...

journal_title：Bioscience reports

authors： Bokka CS,Veeramachaneni GK,Thunuguntla VBSC,Manda NK,Bondili JS

更新日期：2019-11-29 00:00:00

abstract：:Long non-coding RNA (lncRNA) H19 has been implicated in tumor angiogenesis. However, whether H19 regulates the progression of corneal neovascularization (CNV) is unclear. The present study aimed to determine the function of H19 in CNV and its possible molecular mechanism. Here, we found that the H19 levels were remark...

journal_title：Bioscience reports

authors： Sun B,Ding Y,Jin X,Xu S,Zhang H

更新日期：2019-05-02 00:00:00