Long non-coding RNA H19 promotes corneal neovascularization by targeting microRNA-29c.

abstract：:Kawasaki disease (KD) is a type of disease that includes the development of a fever that lasts at least 5 days and involves the clinical manifestation of multicellular vasculitis. KD has become one of the most common pediatric cardiovascular diseases. Previous studies have reported that miR-218 rs11134527 A>G is assoc...

journal_title：Bioscience reports

authors： Pi L,Fu L,Xu Y,Che D,Deng Q,Huang X,Li M,Zhang L,Huang P,Gu X

更新日期：2018-05-22 00:00:00

abstract：BACKGROUND:Breast cancer (BC) is the most common malignancy among females worldwide. The tumor microenvironment usually prevents effective lymphocyte activation and infiltration, and suppresses infiltrating effector cells, leading to a failure of the host to reject the tumor. CC chemokines play a significant role in in...

journal_title：Bioscience reports

authors： Chen B,Zhang S,Li Q,Wu S,He H,Huang J

更新日期：2020-11-27 00:00:00

abstract：:Lung surfactant protein A (SP-A) is the most abundant surfactant-associated protein present in the lung. A receptor for SP-A has been shown to be present on A549 alveolar type II cells and on other cell types, including alveolar macrophage. The SP-A receptor on A549 cells has been identified as the collection receptor...

journal_title：Bioscience reports

authors： Malhotra R,Haurum J,Thiel S,Jensenius JC,Sim RB

更新日期：1993-04-01 00:00:00

abstract：:31p nuclear magnetic resonance (NMR) spectra have been obtained from animal and human tumours grown in laboratory rodents. The tumour cells are only slightly more acid than the surrounding muscle but they tend to have large Pi and sugar phosphate peaks, suggesting anoxia, and large but variable phosphodiester peaks. T...

journal_title：Bioscience reports

authors： Griffiths JR,Iles RA

更新日期：1982-09-01 00:00:00

abstract：:Common colds were shortened by 7 days in a 1984 clinical trial using zinc gluconate throat lozenges each 2 h. Between then and 2004, 10 other double-blind, placebo-controlled clinical trials showed widely varying results. This re-analysis of these trials presents solution chemistry methods to elucidate differences in ...

journal_title：Bioscience reports

authors： Eby GA

更新日期：2004-02-01 00:00:00

abstract：:The cellular onc-genes c-src and c-yes are expressed very differently during chicken embryonic development. The c-src mRNA and its translational product are detectable at high levels in brain extracts of chicken embryos and adult chickens, whereas muscle extracts show an age-dependent decrease in the amounts of c-src-...

journal_title：Bioscience reports

authors： Gessler M,Barnekow A

更新日期：1984-09-01 00:00:00

abstract：:Capacity to synthesize glucose, urea, and ketone bodies is well maintained in hepatocytes after storage for at least 24 h at 4 degrees C. Substrates and albumin are the only requirements. ...

journal_title：Bioscience reports

authors： Farrell R,Lund P

更新日期：1983-06-01 00:00:00

abstract：:CYP (cytochrome P450) 3A29 in pigs could be an important candidate gene responsible for xenobiotic metabolism, similar to CYP3A4 in humans. Accordingly, the tissue expression of CYP3A29 mRNA in domestic pigs has been determined by a real-time PCR. The enzymatic properties of CYP3A29, CYP3A4 and PLM (pig liver microsom...

journal_title：Bioscience reports

authors： Yao M,Dai M,Liu Z,Huang L,Chen D,Wang Y,Peng D,Wang X,Liu Z,Yuan Z

更新日期：2011-06-01 00:00:00

abstract：:Previous studies demonstrated that the adaptive response to stressors and inflammatory signals involves the activation of the autonomous [corrected] nervous system. Catecholamines have been shown to modulate the activity of various immune effector cells directly via membrane adrenergic receptors. Here, we investigated...

journal_title：Bioscience reports

authors： Lünemann JD,Buttgereit F,Tripmacher R,Baerwald CG,Burmester GR,Krause A

更新日期：2001-10-01 00:00:00

abstract：:Fungal endophytes are known to secrete a large array of secondary metabolites (phenols, flavonoids, indole acetic acid (IAA) etc.) that facilitate crops under stress conditions. Considering this, a potent plant growth promoting endophyte (SXSp1) from the spines and leaves of Solanum xanthocarpum L. has been isolated. ...

journal_title：Bioscience reports

authors： Jan FG,Hamayun M,Hussain A,Iqbal A,Jan G,Khan SA,Khan H,Lee IJ

更新日期：2019-10-30 00:00:00

abstract：:Citrullus lanatus (Cucurbitaceae) is conventionally used for the treatment of urinary tract infection, renal stones, hypertension, diabetes and diarrhoea. Current study evaluates acute and 28 days repeated toxicity ethanolic extract of C. lanatus seed (EECLS) in Wistar rats to measure its safety profile. The single do...

journal_title：Bioscience reports

authors： Belemkar S,Shendge PN

更新日期：2021-01-29 00:00:00

abstract：OBJECTIVE:The current study aimed to investigate the functional roles and clinical significance of microRNA-148a (miR-148a) in the progression of oral squamous cell carcinoma (OSCC). METHODS:Relative expression of miR-148a in OSCC cells and tissues were detected using quantitative real-time polymerase chain reaction (...

journal_title：Bioscience reports

authors： Jia T,Ren Y,Wang F,Zhao R,Qiao B,Xing L,Ou L,Guo B

更新日期：2020-04-30 00:00:00

abstract：:Human endothelial cells from the umbilical vein and skin fibroblasts can be separated by means of centrifugation in a density gradient of Percoll. Cells show a good recovery in culture. Viability is not impaired. ...

journal_title：Bioscience reports

authors： Sbarbati R

更新日期：1985-06-01 00:00:00

abstract：:The relative proportions of immunoregulatory T-cell subpopulations defined by OKT monoclonal antibodies are disturbed in chronic lymphocytic leukaemia (CLL) patients (even early mild cases) compared with normal subjects in the same age range. The mean ratio OKT4+:OKT8+ (helper:suppressor/cytotoxic) is reversed from th...

journal_title：Bioscience reports

authors： Johnstone AP,Height S,Millard RE

更新日期：1982-08-01 00:00:00

abstract：:The first demonstration of a method to incorporate radiolabeled methyl groups from [14C]formaldehyde into membrane proteins in human erythrocytes by reductive methylation in the presence of NaCNBH3 is described. This method is based on the work of Jentoft and Dearborn [(1979) J. Biol. Chem. 254, 4359-4365], who demons...

journal_title：Bioscience reports

authors： Butterfield DA,Shahabuddin M

更新日期：1982-04-01 00:00:00

abstract：:Dendritic cells (DCs) present exogenous antigens on major histocompatibility complex (MHC) class I molecules, thereby activating CD8+ T cells, contributing to tumor elimination through a mechanism known as antigen cross-presentation. A variety of factors such as maturation state of DCs, co-stimulatory signals, T-cell ...

journal_title：Bioscience reports

authors： Warrier VU,Makandar AI,Garg M,Sethi G,Kant R,Pal JK,Yuba E,Gupta RK

更新日期：2019-10-30 00:00:00

abstract：:Gastric cancer (GC) is one of the most prevalent gastrointestinal malignancies. Long noncoding RNA (lncRNA) DANCR is a newly identified oncogenic lncRNA. However, the functional role and underlying molecular mechanisms of DANCR involved in GC progress remain unclear. In the present study, we investigated the biologica...

journal_title：Bioscience reports

authors： Mao Z,Li H,Du B,Cui K,Xing Y,Zhao X,Zai S

更新日期：2017-11-06 00:00:00

abstract：:Mouse Mex3c encodes RNA-binding proteins of variant length through alternative splicing. Its mutation results in multiple defects including growth retardation, perturbed energy balance, and defective antiviral innate immunity. Here we report that Mex3c mutation affects mammary gland development and lactation in female...

journal_title：Bioscience reports

authors： Du Y,Sun D,Li Y

更新日期：2020-12-23 00:00:00

abstract：:The concentration of carbonic anhydrase III (CAIII) in male rat liver was found to be 30 times greater than that in the female. Castration of male rats led to marked reduction in liver CAIII concentrations which could be partially restored to control levels by testosterone replacement. Marked developmental and senesce...

journal_title：Bioscience reports

authors： Shiels A,Jeffery S,Phillips IR,Shephard EA,Wilson CA,Carter ND

更新日期：1983-05-01 00:00:00

abstract：:Canstatin, the non-collagenous domain of collagen type IV α-chains, belongs to a series of collagen-derived angiogenic inhibitors. In this study, the inhibitory effect of recombinant canstatin on tumour growth was investigated using a gastric cancer xenograft model. The volume and weight of tumours in mice treated wit...

journal_title：Bioscience reports

authors： Xing YN,Deng P,Xu HM

更新日期：2014-04-01 00:00:00

abstract：:Western blotting was used as a powerful alternative to immunoprecipitation for the detection of the simian virus 40 (SV40) large tumor (T) antigen. After resolution by electrophoresis on a SDS-polyacrylamide gel of a [35S]methionine labeled crude extract from SV40 infected monkey kidney cells, the separated proteins w...

journal_title：Bioscience reports

authors： Dietrich JB

更新日期：1985-02-01 00:00:00

abstract：:High-affinity binding of 3H-folate in Triton X-100 solubilized membranes of human liver displayed characteristics, e.g. apparent positive cooperativity, which are typical of specific folate binding. Ultrogel AcA 44 chromatography of solubilized membranes saturated with 3H-folate revealed a major peak of 100 kDa and a ...

journal_title：Bioscience reports

authors： Holm J,Hansen SI,Høier-Madsen M

更新日期：1991-06-01 00:00:00

abstract：:Matrix-bound monoclonal antibodies against urokinase have been used to purify this enzyme by affinity chromatography. In a single-step procedure, urokinase can be isolated from crude preparations with high yield and high purity, and without loss of enzymatic activity. ...

journal_title：Bioscience reports

authors： Hérion P,Bollen A

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a tumor that is commonly found in southern China. NPC has several risk factors, such as infection with the Epstein-Barr virus. However, we know little about the risk factors for eye metastasis (EM) in male patients with NPC. Serum lipids are well recognized as risk factors f...

journal_title：Bioscience reports

authors： Xie Z,Shao Y

更新日期：2020-06-26 00:00:00

abstract：:Sendai virus envelopes (SVE) were isolated from Sendai virus particles by Triton X-100 solubilization and ultracentrifugation. The envelopes were reconstituted in the presence of the fluorescent dye calcein by gradual removal of the detergent with Bio-beads SM-2. The internal volume of reconstituted Sendai virus envel...

journal_title：Bioscience reports

authors： Bartzatt RL,Volsky DJ

更新日期：1984-07-01 00:00:00

abstract：:The inhibition of passive K+ influx into human red blood cells (RBC) by loop diuretics was found to be dependent on the external Na+ concentration. In the absence of external Na+, there was minimal inhibition but the influx remained dependent on Cl- ions. Thus, raising the external Na+ concentration increased the affi...

journal_title：Bioscience reports

authors： Chipperfield AR

更新日期：1985-04-01 00:00:00

abstract：:Although membrane fusion occurs ubiquitously and continuously in all eukaroytic cells, little is known about the mechanism that governs lipid bilayer fusion associated with any intracellular fusion reactions. Recent studies of the fusion of enveloped viruses with host cell membranes have helped to define the fusion pr...

journal_title：Bioscience reports

authors： Martin I,Ruysschaert JM

更新日期：2000-12-01 00:00:00

abstract：:Hospital-acquired infections are common in burn patients and are the major contributors of morbidity and mortality. Bacterial infections such as Staphylococcus aureus (S. aureus) and Acinetobacter baumannii (A. baumannii) are difficult to treat due to their biofilm formation and rapidly acquiring resistance to antibio...

journal_title：Bioscience reports

authors： Khan A,Xu M,Wang T,You C,Wang X,Ren H,Zhou H,Khan A,Han C,Li P

更新日期：2019-06-18 00:00:00

abstract：:Objective: We aimed to assess the possible relations between serum levels of macrophage migration inhibitory factor (MIF), a central cytokine of the innate immunity and inflammatory response, and benign paroxysmal positional vertigo (BPPV) risk and BPPV recurrence events.Methods: In the present study, 154 patients wit...

journal_title：Bioscience reports

authors： Cai HB,Duan L,Tian T,Li ZC,Zhao CC,Ge ZM

更新日期：2019-08-23 00:00:00

abstract：:Hepatocellular carcinoma (HCC) has a high recurrence rate and poor clinical outcome after currently used therapies, including radiofrequency ablation. To explore the possible mechanisms for the relapse of HCC, in the present study we focussed on long non-coding RNA (LncRNA), which has been reported to be involved in t...

journal_title：Bioscience reports

authors： Zhu X,Yu H,Li B,Quan J,Zeng Z,Li G,Liu J

更新日期：2019-11-29 00:00:00