Abstract:
:Self-assembly of electroactive molecules is a promising route to new types of functional semiconductors. Here we report a capsule-shaped molecule that assembles itself into a cellular semiconducting material. The interior space of the capsule with a volume of ~415 Å3 is a nanoenvironment that can accommodate a guest. To self-assemble these capsules into electronic materials, we functionalize the thiophene rings with bromines, which encode self-assembly into two-dimensional layers held together through halogen bonding interactions. In the solid state and in films, these two-dimensional layers assemble into the three-dimensional crystalline structure. This hollow material is able to form the active layer in field effect transistor devices. We find that the current of these devices has strong response to the guest's interaction within the hollow spaces in the film. These devices are remarkable in their ability to distinguish, through their electrical response, between small differences in the guest.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Zhang B,Hernández Sánchez R,Zhong Y,Ball M,Terban MW,Paley D,Billinge SJL,Ng F,Steigerwald ML,Nuckolls Cdoi
10.1038/s41467-018-04246-0subject
Has Abstractpub_date
2018-05-16 00:00:00pages
1957issue
1issn
2041-1723pii
10.1038/s41467-018-04246-0journal_volume
9pub_type
杂志文章abstract::Warming in the Arctic accelerates thawing of permafrost-affected soils, which leads to a release of greenhouse gases to the atmosphere. We do not know whether permafrost thaw also releases non-methane volatile organic compounds that can contribute to both negative and positive radiative forcing on climate. Here we sho...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05824-y
更新日期:2018-08-24 00:00:00
abstract::Charge acceleration during an intense light field application to solids attracts much attention as elementary processes in high-harmonic generation and photoelectron emission. For manipulating such attosecond dynamics of charge, carrier-envelope-phase (CEP: relative phase between carrier oscillation of light field and...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17776-3
更新日期:2020-08-18 00:00:00
abstract::Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, which are currently unavailable for a substantial fraction of microbial species, introduces estimation biases. We ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08844-4
更新日期:2019-03-04 00:00:00
abstract::The original version of this article contained an error in the author affiliations. Oliver J. Furzer was incorrectly associated with Department of Plant Sciences, College of Life Sciences, Wuhan University, 430072, Wuhan, China.This has now been corrected in the HTML version of the article. The PDF version of the arti...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-08095-9
更新日期:2019-01-08 00:00:00
abstract::Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, merit metabolic homoeostasis. We hence conducted a randomized, double-blind, placebo-controlled trial with newly diagnosed T2D patie...
journal_title:Nature communications
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41467-020-18414-8
更新日期:2020-10-06 00:00:00
abstract::Phosphorylation is a major post-translational mechanism of regulation that frequently targets disordered protein domains, but it remains unclear how phosphorylation modulates disordered states of proteins. Here we determine the kinetics and energetics of a disordered protein domain the kinase-inducible domain (KID) of...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6272
更新日期:2014-10-28 00:00:00
abstract::Iridium N-heterocyclic carbene (NHC) complexes catalyse the para-hydrogen-induced hyperpolarization process, Signal Amplification by Reversible Exchange (SABRE). This process transfers the latent magnetism of para-hydrogen into a substrate, without changing its chemical identity, to dramatically improve its nuclear ma...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06766-1
更新日期:2018-10-12 00:00:00
abstract::Zika virus (ZIKV) is an emerging mosquito borne flavivirus and a major public health concern causing severe disease. Due to the presence of a lipid membrane and structural heterogeneity, attaining an atomic resolution structure is challenging, but important to understand virus assembly and life cycle mechanisms that o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18747-4
更新日期:2020-10-02 00:00:00
abstract::With the development of ultrafast electron and X-ray sources it is becoming possible to study structural dynamics with atomic-level spatial and temporal resolution. Because of their short mean free path, electrons are particularly well suited for investigating surfaces and thin films, such as the challenging and impor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2700
更新日期:2013-01-01 00:00:00
abstract::Achieving and exceeding diversity of colloidal analogs of chemical elements and molecules as building blocks of matter has been the central goal and challenge of colloidal science ever since Einstein introduced the colloidal atom paradigm. Recent advances in colloids assembly have been achieved by exploiting the machi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09777-8
更新日期:2019-04-23 00:00:00
abstract::In silico quantification of cell proportions from mixed-cell transcriptomics data (deconvolution) requires a reference expression matrix, called basis matrix. We hypothesize that matrices created using only healthy samples from a single microarray platform would introduce biological and technical biases in deconvoluti...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07242-6
更新日期:2018-11-09 00:00:00
abstract::Non-linear interactions in coherent gases are not only at the origin of bright and dark solitons and superfluids; they also give rise to phenomena such as multistability, which hold great promise for the development of advanced photonic and spintronic devices. In particular, spinor multistability in strongly coupled s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3008
更新日期:2013-01-01 00:00:00
abstract::Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324 participants from four ancestries at mean depth >29X and analyze genotypes with four quantitative traits-plasma total cholesterol, low-density lipoprotein cholesterol (L...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05747-8
更新日期:2018-08-23 00:00:00
abstract::Metal-halide perovskites have been shown to be remarkable and promising optoelectronic materials. However, despite ongoing research from multiple perspectives, some fundamental questions regarding their optoelectronic properties remain controversial. One reason is the high-variance of data collected from, often unstab...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14365-2
更新日期:2020-01-24 00:00:00
abstract::Tissue injury and the healing response lead to the release of endogenous danger signals including Toll-like receptor (TLR) and interleukin-1 receptor, type 1 (IL-1R1) ligands, which modulate the immune microenvironment. Because TLRs and IL-1R1 have been shown to influence the repair process of various tissues, we expl...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11051
更新日期:2016-03-22 00:00:00
abstract::Selective thermal emission in a useful range of energies from a material operating at high temperatures is required for effective solar thermophotovoltaic energy conversion. Three-dimensional metallic photonic crystals can exhibit spectral emissivity that is modified compared with the emissivity of unstructured metals...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3630
更新日期:2013-01-01 00:00:00
abstract::It is generally believed that the remarkable sensitivity and frequency selectivity of mammalian hearing depend on outer hair cell-generated force, which amplifies sound-induced vibrations inside the cochlea. This 'reverse transduction' force production has never been demonstrated experimentally, however, in the living...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10282
更新日期:2016-01-06 00:00:00
abstract::Bone tissue, by definition, is an organic-inorganic nanocomposite, where metabolically active cells are embedded within a matrix that is heavily calcified on the nanoscale. Currently, there are no strategies that replicate these definitive characteristics of bone tissue. Here we describe a biomimetic approach where a ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11455-8
更新日期:2019-08-06 00:00:00
abstract::Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects). We find 11 genome-wide-sign...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5926
更新日期:2014-10-29 00:00:00
abstract::The fields of soft polymers and macromolecular sciences have enjoyed a unique combination of metals and organic frameworks in the name of metallopolymers or organometallic polymers. When metallopolymers carry charged groups, they form a class of metal-containing polyelectrolytes or metallo-polyelectrolytes. This revie...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-018-06475-9
更新日期:2018-10-18 00:00:00
abstract::Cortical neurons are often functionally heterogeneous even for molecularly defined subtypes. In sensory cortices, physiological responses to natural stimuli can be sparse and vary widely even for neighboring neurons. It is thus difficult to parse out circuits that encode specific stimuli for further experimentation. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03183-2
更新日期:2018-02-28 00:00:00
abstract::Transcription initiation involves the coordinated activities of large multimeric complexes, but little is known about their biogenesis. Here we report several principles underlying the assembly and topological organization of the highly conserved SAGA and NuA4 co-activator complexes, which share the Tra1 subunit. We s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13243-w
更新日期:2019-11-20 00:00:00
abstract::Chloroplasts communicate information by signalling to nuclei during acclimation to fluctuating light. Several potential operating signals originating from chloroplasts have been proposed, but none have been shown to move to nuclei to modulate gene expression. One proposed signal is hydrogen peroxide (H2O2) produced by...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00074-w
更新日期:2017-06-29 00:00:00
abstract::Triacylglycerols are among the most attractive alternative raw materials for biofuel development. Current oil plant-based technologies are limited in terms of triacylglycerol production capacity and rate. These limitations may be circumvented by biotransformation of carbohydrates into lipids; however, our understandin...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2112
更新日期:2012-01-01 00:00:00
abstract::Quantum metrology bears a great promise in enhancing measurement precision, but is unlikely to become practical in the near future. Its concepts can nevertheless inspire classical or hybrid methods of immediate value. Here we demonstrate NOON-like photonic states of m quanta of angular momentum up to m=100, in a setup...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3432
更新日期:2013-01-01 00:00:00
abstract::Zika virus is a mosquito-borne flavivirus closely related to dengue virus that can cause severe disease in humans, including microcephaly in newborns and Guillain-Barré syndrome in adults. Specific treatments and vaccines for Zika virus are not currently available. Here, we isolate and characterize four monoclonal ant...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07008-0
更新日期:2018-11-01 00:00:00
abstract::Ice-shelf channels are long curvilinear tracts of thin ice found on Antarctic ice shelves. Many of them originate near the grounding line, but their formation mechanisms remain poorly understood. Here we use ice-penetrating radar data from Roi Baudouin Ice Shelf, East Antarctica, to infer that the morphology of severa...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15228
更新日期:2017-05-09 00:00:00
abstract::Methane cold seep systems typically exhibit extensive buildups of authigenic carbonate minerals, resulting from local increases in alkalinity driven by methane oxidation. Here, we demonstrate that modern seep authigenic carbonates exhibit anomalously low clumped isotope values (Δ47), as much as ∼0.2‰ lower than expect...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12274
更新日期:2016-07-22 00:00:00
abstract::Expression of oestrogen receptor (ESR1) determines whether a breast cancer patient receives endocrine therapy, but does not guarantee patient response. The molecular factors that define endocrine response in ESR1-positive breast cancer patients remain poorly understood. Here we characterize the DNA methylome of endocr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8758
更新日期:2015-07-14 00:00:00
abstract::Natural killer (NK) cells are cytotoxic innate lymphoid cells that are involved in immune defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory receptors, but the underlying molecular mechanisms remain undefined. Using a mouse model of conditional deletion in NK cells, we show here...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6108
更新日期:2014-10-30 00:00:00