Cardiovascular responses to dry apnoeas at exercise in air and in pure oxygen.

Abstract:

:If, as postulated, the end of the steady state phase (φ2) of cardiovascular responses to apnoea corresponds to the physiological breaking point, then we may hypothesize that φ2 should become visible if exercise apnoeas are performed in pure oxygen. We tested this hypothesis on 9 professional divers by means of continuous recording of blood pressure (BP), heart rate (fH), stroke volume (QS), and arterial oxygen saturation (SpO2) during dry maximal exercising apnoeas in ambient air and in oxygen. Apnoeas lasted 45.0 ± 16.9 s in air and 77.0 ± 28.9 s in oxygen (p < 0.05). In air, no φ2 was observed. Conversely, in oxygen, a φ2 of 28 ± 5 s duration appeared, during which systolic BP (185 ± 29 mmHg), fH (93 ± 16 bpm) and QS (91 ± 16 ml) remained stable. End-apnoea SpO2 was 95.5 ± 1.9% in air and 100% in oxygen. The results support the tested hypothesis.

authors

Taboni A,Vinetti G,Bruseghini P,Camelio S,D'Elia M,Moia C,Ferretti G,Fagoni N

doi

10.1016/j.resp.2018.05.003

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

17-21

eissn

1569-9048

issn

1878-1519

pii

S1569-9048(18)30073-9

journal_volume

255

pub_type

杂志文章
  • Multidimensional aspects of dyspnea in obese patients referred for cardiopulmonary exercise testing.

    abstract::We investigated the contributions of obesity on multidimensional aspects of dyspnea on exertion (DOE) in patients referred for clinical cardiopulmonary exercise testing (CPET). Ratings of perceived breathlessness (RPB, Borg scale 0-10) were collected in obese (BMI ≥ 30; n = 47) and nonobese (BMI ≤ 25; n = 27) patients...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2019.103365

    authors: Balmain BN,Weinstein K,Bernhardt V,Marines-Price R,Tomlinson AR,Babb TG

    更新日期:2020-03-01 00:00:00

  • Effect of heavy-intensity 'priming' exercise on oxygen uptake and muscle deoxygenation kinetics during moderate-intensity step-transitions initiated from an elevated work rate.

    abstract::We examined the effect of heavy-intensity 'priming' exercise on the rate of adjustment of pulmonary O2 uptake (τV˙O2p) initiated from elevated intensities. Fourteen men (separated into two groups: τV˙O2p≤25s [Fast] or τV˙O2p>25s [Slow]) completed step-transitions from 20W to 45% lactate threshold (LT; lower-step, LS) ...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2016.09.013

    authors: Nederveen JP,Keir DA,Love LK,Rossiter HB,Kowalchuk JM

    更新日期:2017-01-01 00:00:00

  • Validation of a two-compartment model of ventilation/perfusion distribution.

    abstract::Ventilation (V (A)) to perfusion (Q ) heterogeneity (V (A)/Q ) analyses by a two-compartment lung model (2C), utilizing routine gas exchange measurements and a computer solution to account for O(2) and CO(2) measurements, were compared with multiple inert gas elimination technique (MIGET) analyses and a multi-compartm...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2005.06.002

    authors: Loeppky JA,Caprihan A,Altobelli SA,Icenogle MV,Scotto P,Vidal Melo MF

    更新日期:2006-03-28 00:00:00

  • Dopamine ameliorates bronchoconstriction induced by histaminergic and cholinergic pathways in rabbits.

    abstract::To clarify the potential of dopamine to alter airway tone in the presence of different bronchoconstrictor stimuli, changes in airway function following dopamine administrations were characterized when the bronchial tone was elevated by stimulating the histaminic or cholinergic pathway. Airway resistance, tissue dampin...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2018.10.006

    authors: Fodor GH,Balogh AL,Sudy R,Ivankovits-Kiss O,Babik B,Petak F

    更新日期:2019-01-01 00:00:00

  • Orexinergic modulation of breathing across vigilance states.

    abstract::Basal respiration and respiratory reflex regulations are considerably different during the awake and sleep states. Tidal volume and respiratory frequency diminish during sleep, and hypoxic and hypercapnic ventilatory responses also decline during sleep. Reduced metabolic demand during sleep cannot completely explain t...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2008.03.011

    authors: Kuwaki T

    更新日期:2008-12-10 00:00:00

  • Neonatal bronchopulmonary dysplasia increases neuronal apoptosis in the hippocampus through the HIF-1α and p53 pathways.

    abstract::Neonatal bronchopulmonary dysplasia (BPD) might lead to an increased risk for brain injury. The present study aims to investigate the effects of neonatal BPD on neuronal apoptosis in the hippocampus and cognitive function and to explore the underlying mechanisms. The results revealed that BPD model rat pups exhibited ...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2015.09.011

    authors: Yin R,Yuan L,Ping L,Hu L

    更新日期:2016-01-01 00:00:00

  • Exhaled nasal nitric oxide output is reduced in humans at night during the sleep period.

    abstract::The physiologic function of nasal nitric oxide (NO) release is unknown. In prior experiments, topical NG-nitro-L-arginine methyl ester (L-NAME) on nasal mucosa reduced exhaled nasal NO output and caused daytime sleepiness. We hypothesized that nasal NO output is reduced at night during the sleep period. We measured ex...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2006.08.002

    authors: O'Hearn DJ,Giraud GD,Sippel JM,Edwards C,Chan B,Holden WE

    更新日期:2007-04-16 00:00:00

  • Importance of mitochondrial P(O2) in maximal O2 transport and utilization: a theoretical analysis.

    abstract::In previous calculations of how the O2 transport system limits .VO2(max), it was reasonably assumed that mitochondrial P(O2) (Pm(O2)) could be neglected (set to zero). However, in reality, Pm(O2) must exceed zero and the red cell to mitochondrion diffusion gradient may therefore be reduced, impairing diffusive transpo...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2013.08.020

    authors: Cano I,Mickael M,Gomez-Cabrero D,Tegnér J,Roca J,Wagner PD

    更新日期:2013-12-01 00:00:00

  • Prolonged partial obstruction during sleep is a NREM phenomenon.

    abstract:OBJECTIVE:Prolonged partial obstruction (PPO) is a common finding in sleep studies. Although not verified, it seems to emerge in deep sleep. We study the effect of PPO on sleep architecture or sleep electroencephalography (EEG) frequency. METHODS:Fifteen OSA patients, 15 PPO + OSA patients and 15 healthy subjects unde...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2018.05.009

    authors: Himanen SL,Martikkala L,Sulkamo S,Rutanen A,Huupponen E,Tenhunen M,Saunamäki T

    更新日期:2018-09-01 00:00:00

  • Interaction of tobacco smoke exposure and ovalbumin-sensitization promotes goblet cell and submucosal gland metaplasia in guinea pigs.

    abstract::Exposure to irritants such as tobacco smoke (TS) causes acute airway inflammation. Chronic exposure may cause airway remodeling contributing to enhanced airway resistance. We hypothesize that combining airway sensitization and inhalation of irritants enhances the number of mucous producing cells beyond either agent al...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2013.07.019

    authors: Pavuluri S,Hanus V,Bergren DR

    更新日期:2013-12-01 00:00:00

  • Hypocapnia is associated with increased upper airway expiratory resistance during sleep.

    abstract::We hypothesized that hypocapnia is responsible for increased expiratory resistance during NREM sleep. Hypocapnia was induced by hypoxic hyperventilation in 21 subjects (aged 29.4 ± 7.8 yrs, 10 women, BMI 24.4 ± 4.3 kg/m(2)). Isocapnic hypoxia was induced in 12 subjects of whom, 6 underwent hypocapnic hypoxia in the sa...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2011.04.004

    authors: Sankri-Tarbichi AG,Richardson NN,Chowdhuri S,Rowley JA,Safwan Badr M

    更新日期:2011-07-31 00:00:00

  • Premature birth, homeostatic plasticity and respiratory consequences of inflammation.

    abstract::Infants who are born premature can have persistent apnea beyond term gestation, reemergence of apnea associated with inflammation during infancy, increased risk of sudden unexplained death, and sleep disorder breathing during infancy and childhood. The autonomic nervous system, particularly the central neural networks...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2019.103337

    authors: Gauda EB,McLemore GL

    更新日期:2020-03-01 00:00:00

  • Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body.

    abstract::Carotid bodies are sensory organs for monitoring arterial blood oxygen (O(2)) levels, and the ensuing reflexes maintain cardio-respiratory homeostasis during hypoxia. This article provides a brief update of the role of carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body. Glomus cel...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2012.05.022

    authors: Prabhakar NR

    更新日期:2012-11-15 00:00:00

  • Effects of reflux laryngitis on non-nutritive swallowing in newborn lambs.

    abstract::Reflux laryngitis in infants may be involved not only in laryngeal disorders, but also in disorders of cardiorespiratory control through its impact on laryngeal function. Our objective was to study the effect of reflux laryngitis on non-nutritive swallowing (NNS) and NNS-breathing coordination. Two groups of six newbo...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2014.05.010

    authors: Brisebois S,Samson N,Fortier PH,Doueik AA,Carreau AM,Praud JP

    更新日期:2014-08-15 00:00:00

  • Aerobic exercise training without weight loss reduces dyspnea on exertion in obese women.

    abstract::Dyspnea on exertion (DOE) is a common symptom in obesity. We investigated whether aerobic exercise training without weight loss could reduce DOE. Twenty-two otherwise healthy obese women participated in a 12-week supervised aerobic exercise training program, exercising 30 min/day at 70-80% heart rate reserve, 4 days/w...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2015.11.004

    authors: Bernhardt V,Stickford JL,Bhammar DM,Babb TG

    更新日期:2016-01-15 00:00:00

  • Biphasic airway-lung response to anaphylactic shock in Brown Norway rats.

    abstract::Bronchospasm may be part of the response to systemic anaphylaxis in humans. The anaphylactic shock has been characterized in allergic rats, but little data are available on the concurrent changes in airway-lung mechanics. The aim was to describe the respiratory resistance (Rrs) and reactance (Xrs) response to ovalbumi...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2013.07.003

    authors: Barthel G,Zheng F,Demoulin B,Davidson J,Montémont C,Gaburro J,Mertes PM,Marchal F

    更新日期:2013-10-01 00:00:00

  • Breath-holding test in evaluation of peripheral chemoreflex sensitivity in healthy subjects.

    abstract::The aim of the study was to determine the feasibility of using a breath-holding test in assessing the sensitivity of the peripheral chemoreflex compared with the single-breath carbon dioxide test. The study involved 48 healthy volunteers between the ages of 18-29 years. The breath-holding test was performed followed b...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2016.10.005

    authors: Trembach N,Zabolotskikh I

    更新日期:2017-01-01 00:00:00

  • Limitations of surface EMG estimate of parasternal intercostal to infer neural respiratory drive.

    abstract:BACKGROUND:Recently, surface EMG of parasternal intercostal muscle has been incorporated in the "ERS Statement of Respiratory Muscle Testing" as a clinical technique to monitor the neural respiratory drive (NRD). However, the anatomy of the parasternal muscle risks confounding EMG "crosstalk" activity from neighboring ...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2020.103572

    authors: Tagliabue G,Ji M,Suneby Jagers JV,Lee W,Dean D,Zuege DJ,Wilde ER,Easton PA

    更新日期:2020-11-05 00:00:00

  • Ovarian steroids act as respiratory stimulant and antioxidant against the causes and consequences of sleep-apnea in women.

    abstract::Evidence supports the importance of ovarian hormones as potential tools against sleep apneas in women. On one hand, progesterone is largely acknowledged as being a respiratory stimulant that reduces the frequency of apneas, but the underlying mechanisms remain poorly understood. Recent studies in mice showed that the ...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2017.01.013

    authors: Boukari R,Laouafa S,Ribon-Demars A,Bairam A,Joseph V

    更新日期:2017-05-01 00:00:00

  • Ontogenesis of oxygen chemoreception in aquatic vertebrates.

    abstract::In aquatic vertebrates, peripheral O(2) chemoreceptors initiate compensatory physiological and behavioural responses to hypoxia, beginning at very early stages of development, to maintain sufficient gas exchange across the skin or gills. This review highlights the morphological and physiological studies, particularly ...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2006.01.004

    authors: Jonz MG,Nurse CA

    更新日期:2006-11-01 00:00:00

  • Non-invasive CPAP in mild and moderate ARDS secondary to SARS-CoV-2.

    abstract:BACKGROUND:During the COVID-19 outbreak, a very high number of infected patients developed pneumonia and many of them complicated with acute respiratory distress syndrome. The optimal management of respiratory failure and the role of lung ultrasound imaging in the evaluation of efficacy of treatment are unknown. METHO...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2020.103489

    authors: Pagano A,Porta G,Bosso G,Allegorico E,Serra C,Dello Vicario F,Minerva V,Russo T,Altruda C,Arbo P,Mercurio V,Numis FG

    更新日期:2020-09-01 00:00:00

  • Pre-junctional muscarinic autoreceptors in bovine airways.

    abstract:UNLABELLED:We searched for pre-junctional inhibitory muscarinic receptors in isolated bovine trachealis strips and bronchial rings. Electric stimulation (ES)-induced tritiated acetylcholine ([(3)H]-ACh)-release and isometric contractions were determined in muscles incubated with the non-selective muscarinic agonist pil...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2011.10.007

    authors: Baroffio M,Crimi E,Brichetto L,Zappi L,Rehder K,Brusasco V

    更新日期:2012-01-15 00:00:00

  • Epidemiological and immunological reasons for pertussis vaccination in adolescents and adults.

    abstract::The resurgence of pertussis has been the subject of considerable debate. Hypotheses to explain increased reporting in developed countries have focused mainly on three aspects: (1) increased recognition of the disease in adolescents and adults; (2) waning of vaccine-induced immunity and (3) loss of vaccine efficacy due...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2013.02.007

    authors: Nitsch-Osuch A,Korzeniewski K,Kuchar E,Zielonka T,Życińska K,Wardyn K

    更新日期:2013-06-01 00:00:00

  • Three fatal cases of pandemic 2009 influenza A virus infection in Shenzhen are associated with cytokine storm.

    abstract::China had taken strict measures for pandemic 2009 H1N1 infection with enhanced surveillance and hospital isolation since April 2009. In Shenzhen, over 1200 confirmed cases of H1N1 infection were identified. Three young patients died of severe pneumonia. Among them, two boys developed neurological complications. Cytoki...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2010.11.004

    authors: Cheng XW,Lu J,Wu CL,Yi LN,Xie X,Shi XD,Fang SS,Zan H,Kung HF,He ML

    更新日期:2011-01-31 00:00:00

  • Snoring and sleep disorders in children with hypertrophy of lymphoid tissue in the throat.

    abstract::Hypertrophy of lymphoid tissue within the throat in children leads to a number of respiratory problems and sleep disorders. The aim of this study was to evaluate the prevalence of the above-mentioned changes depending on the location of overgrown lymphoid tissue, BMI, and coexisting allergies. The study was based on a...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2013.02.010

    authors: Dzięciołowska-Baran E,Dąbrowski P,Gawlikowska-Sroka A,Poziomkowska-Gęsicka I,Baran S

    更新日期:2013-06-01 00:00:00

  • Chronic intermittent hyperoxia alters the development of the hypoxic ventilatory response in neonatal rats.

    abstract::Chronic exposure to sustained hyperoxia alters the development of the respiratory control system, but the respiratory effects of chronic intermittent hyperoxia have rarely been investigated. We exposed newborn rats to short, repeated bouts of 30% O2 or 60% O2 (5 bouts h(-1)) for 4-15 days and then assessed their hypox...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2015.09.015

    authors: Logan S,Tobin KE,Fallon SC,Deng KS,McDonough AB,Bavis RW

    更新日期:2016-01-01 00:00:00

  • Fetal lung development in the elephant reflects the adaptations required for snorkeling in adult life.

    abstract::The adult elephant is unique among mammals in that the pleural membranes are thickened and the pleural cavity is obliterated by connective tissue. It has been suggested that this peculiar anatomy developed because the animal can snorkel at depth, and this behavior subjects the microvessels in the parietal pleura to a ...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/s1569-9048(03)00199-x

    authors: West JB,Fu Z,Gaeth AP,Short RV

    更新日期:2003-11-14 00:00:00

  • Perinatal development of respiratory motoneurons.

    abstract::Breathing movements require the coordinated recruitment of cranial and spinal motoneurons innervating muscles of the upper airway and ribcage. A significant part of respiratory motoneuron development and maturation occurs prenatally to support the generation of fetal breathing movements in utero and sustained breathin...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.resp.2005.03.017

    authors: Greer JJ,Funk GD

    更新日期:2005-11-15 00:00:00

  • With age a lower individual breathing reserve is associated with a higher maximal heart rate.

    abstract:INTRODUCTION:Maximal heart rate (HRmax) is linearly declining with increasing age. Regular exercise training is supposed to partly prevent this decline, whereas sex and habitual physical activity do not. High exercise capacity is associated with a high cardiac output (HR x stroke volume) and high ventilatory requiremen...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2017.09.005

    authors: Burtscher M,Gatterer H,Faulhaber M,Burtscher J

    更新日期:2018-01-01 00:00:00

  • Glucocorticoids inhibits the repair of airway epithelial cells via the activation of wnt pathway.

    abstract:BACKGROUND:The purpose of this study was to explore the effect of Wnt pathway on the inhibition of airway epithelial cells repair by glucocorticoid. MATERIALS AND METHODS:The expression of E-cadherin in asthma mice model was detected by immunocytochemistry. XAV939 was used to treat 16HBE, and the expressions of relate...

    journal_title:Respiratory physiology & neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.resp.2019.103283

    authors: Yu Z,Jiang Y,Sun C

    更新日期:2020-01-01 00:00:00