Abstract：
:The resurgence of pertussis has been the subject of considerable debate. Hypotheses to explain increased reporting in developed countries have focused mainly on three aspects: (1) increased recognition of the disease in adolescents and adults; (2) waning of vaccine-induced immunity and (3) loss of vaccine efficacy due to an antigenic shift of Bordetella pertussis. Waning immunity after vaccination or natural infection combined with the absence of regular boosters either in the form of vaccine boosters or natural exposure to B. pertussis - due to the low circulation of the bacterium in well-immunized populations - has been suggested to explain this shift in the age distribution of pertussis. The highest incidence of the disease is currently reported among adolescents and adults who may additionally serve as the source of infection for susceptible infants. Immunological and epidemiological data indicates the need for a universal booster vaccination against pertussis for adolescents and adults.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Nitsch-Osuch A,Korzeniewski K,Kuchar E,Zielonka T,Życińska K,Wardyn Kdoi
10.1016/j.resp.2013.02.007subject
Has Abstractpub_date
2013-06-01 00:00:00pages
99-103issue
1eissn
1569-9048issn
1878-1519pii
S1569-9048(13)00038-4journal_volume
187pub_type
杂志文章,评审abstract：:Submaximal exercise diaphragm blood flow (BF) is elevated in young chronic heart failure (CHF) rats, while it is unknown if this occurs in older animals. Respiratory and hindlimb muscle BFs (radiolabeled microspheres) were measured at rest and during submaximal exercise (20m/min, 5% grade) in older healthy (n=7) and C...
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2015.09.015
更新日期：2016-01-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2020.103547
更新日期：2021-01-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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更新日期：2020-12-14 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2006.08.007
更新日期：2007-04-16 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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更新日期：2013-10-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2011.03.023
更新日期：2011-07-31 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2007.09.012
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journal_title：Respiratory physiology & neurobiology
pub_type： 临床试验,杂志文章
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journal_title：Respiratory physiology & neurobiology
pub_type： 社论,评审
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journal_title：Respiratory physiology & neurobiology
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journal_title：Respiratory physiology & neurobiology
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更新日期：2018-01-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 临床试验,杂志文章
doi：10.1016/j.resp.2007.01.008
更新日期：2007-08-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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更新日期：2010-04-15 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2010.11.004
更新日期：2011-01-31 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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更新日期：2010-06-30 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/s1569-9048(02)00183-0
更新日期：2002-11-19 00:00:00
abstract：:Inorganic nitrate has been shown to reduce oxygen cost during exercise. Since the nitrate-nitrite-NO pathway is facilitated during hypoxia, we investigated the effects of dietary nitrate on oxygen consumption and cardiovascular responses during apnea. These variables were measured in two randomized, double-blind, plac...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,随机对照试验
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更新日期：2013-01-15 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.resp.2011.03.016
更新日期：2011-07-31 00:00:00
