Abstract：
:We examined how the greater vasodilatory capacity of slow--(ST) versus fast-twitch (FT) muscles impacts the relationship between blood flow (Q ) and O2 uptake (VO2) and, consequently, the O2 extraction (a-vO2 diff.)-to-VO2 relationship. Q was measured with radiolabelled microspheres, while VO2 was calculated by the Fick principle using measurements of microvascular O2 pressure (phosphorescence quenching) at rest, low--(2.5 V) and high-intensity contractions (4.5 V) for soleus (Sol; ST, n=5), mixed-gastrocnemius (MG; FT, n=7) and white-gastrocnemius (WG; FT, n=7). The slope of the Q-to-VO2 relationship (delta Q/delta VO2] ) was not different among muscles (Sol = 5.5 +/- 0.2, MG = 6.0 +/- 0.11 and WG = 5.8 +/- 0.06; P > 0.05). In contrast, the intercept was greater (P < 0.05) for Sol (16.3 +/- 2.7 ml min(-1) 100 g(-1)) versus MG and WG (in ml min(-1) 100 g(-1): 1.39 +/- 0.26 and 1.45 +/- 0.23, respectively; MG and WG, P > 0.05). In addition, the a-vO2 diff.-to-VO2] relationship for Sol was shifted rightward compared to MG and WG. These data suggest that the increase in Q for a given change in VO2 is similar for slow- and fast-twitch muscles, at least for the range of metabolic rates and muscles studied herein and that a-vO2 diff. differences result from the lower resting Q in FT muscles.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Ferreira LF,McDonough P,Behnke BJ,Musch TI,Poole DCdoi
10.1016/j.resp.2005.11.004keywords:
subject
Has Abstractpub_date
2006-10-27 00:00:00pages
237-49issue
3eissn
1569-9048issn
1878-1519pii
S1569-9048(05)00275-2journal_volume
153pub_type
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pub_type： 临床试验,杂志文章
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更新日期：2005-01-15 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/s1569-9048(03)00027-2
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pub_type： 杂志文章
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/s1569-9048(02)00204-5
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
doi：10.1016/j.resp.2009.08.005
更新日期：2009-10-31 00:00:00
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更新日期：2016-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.resp.2017.01.007
更新日期：2017-05-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.resp.2007.10.001
更新日期：2008-02-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.resp.2014.07.009
更新日期：2014-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.resp.2012.11.010
更新日期：2013-02-01 00:00:00
