Abstract：
:Dyspnoea, the perception of an unpleasant and/or uncomfortable sensation of breathlessness, offers several physiological, anatomical and teleological analogies with pain. Pain perception has been shown to exist in the newborn, suggesting that dyspnoea may also occur from birth onwards. The perception of breathlessness will be subservient to developmental changes in the behaviour of sensors and lung and muscular receptors implicated in dyspnoea, some of which are known to be active at time of birth. For example, perinatal resetting of the arterial chemoreceptor could lead to transient depression of the dyspnoeic response to hypoxia. However, though early evoked ventilatory responses and peripheral receptor maturation do exist, dyspnoea will only occur if the corresponding central neural circuitry undergoes parallel maturation. Our knowledge of dyspnoea in later childhood is based on a small number of clinical or psychophysical studies, predominantly dealing with asthma and exercise. There is a thus a clear need for systematic assessment of the existence and severity of dyspnoea sensing in younger children that takes into account its role as an alarm mechanism for triggering adaptive and/or protective responses.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Schweitzer C,Marchal Fdoi
10.1016/j.resp.2008.12.001subject
Has Abstractpub_date
2009-05-30 00:00:00pages
144-53issue
1eissn
1569-9048issn
1878-1519pii
S1569-9048(08)00325-Xjournal_volume
167pub_type
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更新日期：2014-08-15 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 临床试验,杂志文章
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更新日期：2004-06-25 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2020.103510
更新日期：2020-10-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2008.12.011
更新日期：2009-02-28 00:00:00
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pub_type： 杂志文章
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更新日期：2013-10-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2015.03.007
更新日期：2015-07-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2016.10.013
更新日期：2017-02-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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更新日期：2007-04-16 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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更新日期：2007-02-15 00:00:00
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pub_type： 社论,评审
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更新日期：2009-05-30 00:00:00
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更新日期：2009-10-01 00:00:00
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更新日期：2020-03-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章
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更新日期：2020-11-01 00:00:00
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更新日期：2013-10-01 00:00:00
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更新日期：2020-01-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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更新日期：2019-05-01 00:00:00
