Abstract：
:Lung ultrasonography (LUS) and computed tomography (CT) were compared for quantitative assessment of extravascular lung water (EVLW) in 10 isolated bovine lung lobes. LUS and CT were obtained at different inflation pressures before and after instillation with known amounts of hypotonic saline. A video-based quantitative LUS analysis was superior to both single-frame quantitative analysis and visual scoring in the assessment of EVLW. Video-based mean LUS intensity was strongly correlated with EVLW density (r(2)=0.87) but weakly correlated with mean CT attenuation (r(2)=0.49) and physical density (r(2)=0.49). Mean CT attenuation was weakly correlated with EVLW density (r(2)=0.62) but strongly correlated with physical density (r(2)=0.99). When the effect of physical density was removed by partial correlation analysis, EVLW density was significantly correlated with video-based LUS intensity (r(2)=0.75) but not mean CT attenuation (r(2)=0.007). In conclusion, these findings suggest that quantitative LUS by video gray-scale analysis can assess EVLW more reliably than LUS visual scoring or quantitative CT.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Corradi F,Ball L,Brusasco C,Riccio AM,Baroffio M,Bovio G,Pelosi P,Brusasco Vdoi
10.1016/j.resp.2013.04.002subject
Has Abstractpub_date
2013-07-01 00:00:00pages
244-9issue
3eissn
1569-9048issn
1878-1519pii
S1569-9048(13)00097-9journal_volume
187pub_type
杂志文章abstract：:The postnatally developing lungs of the quokka wallaby, Setonix brachyurus, were investigated macroscopically and by light microscopic morphometry. Lung, parenchymal and non-parenchymal volumes as well as the components of the latter two were analysed by regression analysis. The lungs comprised a single undivided left...
journal_title：Respiratory physiology & neurobiology
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journal_title：Respiratory physiology & neurobiology
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abstract：:Hypoxic exposure lasting a few hours results in an elevation of ventilation and a lowering of end-tidal P(CO2) (P(ET(CO2))) that persists on return to breathing air. We sought to determine whether this increment in ventilation is fixed (hypothesis 1), or whether it increases in proportion to the rise in metabolic rate...
journal_title：Respiratory physiology & neurobiology
pub_type： 临床试验,杂志文章
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journal_title：Respiratory physiology & neurobiology
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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更新日期：2008-12-10 00:00:00
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doi：10.1016/j.resp.2015.11.009
更新日期：2016-03-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
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更新日期：2011-08-31 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.resp.2010.01.004
更新日期：2010-04-15 00:00:00
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journal_title：Respiratory physiology & neurobiology
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更新日期：2020-01-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2013.06.006
更新日期：2013-08-15 00:00:00
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doi：10.1016/j.resp.2013.07.003
更新日期：2013-10-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
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doi：10.1016/s0034-5687(01)00337-1
更新日期：2002-04-01 00:00:00
abstract：:Acetylcholine and ATP appear to mediate excitatory transmission between receptor (glomus) cells and the petrosal ganglion (PG) neuron terminals in the carotid body. In most species these putative transmitters are excitatory, while inhibitory effects had been reported in the rabbit. We studied the effects of the applic...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2010.05.003
更新日期：2010-07-31 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/s1569-9048(02)00150-7
更新日期：2002-10-23 00:00:00
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更新日期：2019-04-01 00:00:00
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更新日期：2019-04-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
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更新日期：2013-11-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2007.10.001
更新日期：2008-02-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2013-03-01 00:00:00
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journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
doi：10.1016/s1569-9048(03)00045-4
更新日期：2003-05-30 00:00:00
abstract：:The lung surfactant dipalmitoylphosphatidylcholine (DPPC) most probably leaks into the blood, settling on the luminal aspect of blood vessels to create active hydrophobic spots (AHS). Nanobubbles are formed at these spots from dissolved gas. We hypothesized that when a large molecule in the blood comes into contact wi...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2020.103615
更新日期：2021-01-06 00:00:00
abstract：:Seizure-induced cardiorespiratory autonomic dysfunction is a major cause of sudden unexpected death in epilepsy (SUDEP), and the underlying mechanism is unclear. Seizures lead to increased synthesis, and release of glutamate, pituitary adenylate cyclase activating polypeptide (PACAP), and other neurotransmitters, and ...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2016.01.003
更新日期：2016-06-01 00:00:00
abstract：:Exposure to irritants such as tobacco smoke (TS) causes acute airway inflammation. Chronic exposure may cause airway remodeling contributing to enhanced airway resistance. We hypothesize that combining airway sensitization and inhalation of irritants enhances the number of mucous producing cells beyond either agent al...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2013.07.019
更新日期：2013-12-01 00:00:00
abstract：:We investigated the signal transmission pathway by which activation of μ-opioid receptors attenuates acetylcholine (ACh) release in bovine trachealis. Electrical stimulation (ES)-induced [(3)H]-ACh release was determined in bovine tracheal smooth muscle strips pre-incubated with either the Gi-protein inhibitor pertuss...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章
doi：10.1016/j.resp.2013.07.021
更新日期：2013-10-01 00:00:00
abstract：:Asthma is a chronic inflammatory disease, with an array of cells involved in the pathogenesis of the disease. The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes partic...
journal_title：Respiratory physiology & neurobiology
pub_type： 杂志文章,评审
doi：10.1016/j.resp.2014.12.004
更新日期：2015-04-01 00:00:00
