Abstract:
:The aim of the study was to determine the feasibility of using a breath-holding test in assessing the sensitivity of the peripheral chemoreflex compared with the single-breath carbon dioxide test. The study involved 48 healthy volunteers between the ages of 18-29 years. The breath-holding test was performed followed by the single-breath carbon dioxide test on the next day. A month after the first tests, these tests were repeated to evaluate their reproducibility The coefficient of variability in the single-breath carbon dioxide test ranged from 0 to 32% with a mean of 10±7%. The mean coefficient of variability of the breath-holding test was 6±4% (0-19%). A significant inverse correlation between the results of the two tests was noted following analysis (r=-0.82, p<0.05). CONCLUSION:A breath-holding test after deep inspiration reflects the sensitivity of the peripheral chemoreflex as defined by the single-breath carbon dioxide test in healthy subjects.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Trembach N,Zabolotskikh Idoi
10.1016/j.resp.2016.10.005subject
Has Abstractpub_date
2017-01-01 00:00:00pages
79-82eissn
1569-9048issn
1878-1519pii
S1569-9048(16)30155-0journal_volume
235pub_type
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