Design and Applications of Cell-Selective Surfaces and Interfaces.

abstract：:Thermoresponsive oligo(ethylene glycol)-based copolymers were investigated for trypsin conjugation. These copolymers have been synthesized by atom transfer radical polymerization of 2-(2-methoxyethoxy)ethyl methacrylate (MEO(2)MA) with oligo(ethylene glycol) methyl ether methacrylate (OEGMA(475), M(n) = 475 g.mol(-1))...

journal_title：Biomacromolecules

authors： Zarafshani Z,Obata T,Lutz JF

更新日期：2010-08-09 00:00:00

abstract：:Functionally designed elastomeric nanofiber fabrics made of the equimolar copolyester, poly(L-lactide-co-epsilon-caprolactone) (PLCL), with type I collagen or the tri-n-butylamine salt of heparin (heparin-TBA) were co-electrospun using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as a solvent. The co-electrospun fabrics (...

journal_title：Biomacromolecules

authors： Kwon IK,Matsuda T

更新日期：2005-07-01 00:00:00

abstract：:Heparins are widely used to prevent blood clotting during surgeries and for the treatment of thrombosis. However, bleeding associated with heparin therapy is a concern. Protamine, the only approved antidote for unfractionated heparin (UFH) could cause adverse cardiovascular events. Here, we describe a unique molecular...

journal_title：Biomacromolecules

authors： Kalathottukaren MT,Abbina S,Yu K,Shenoi RA,Creagh AL,Haynes C,Kizhakkedathu JN

更新日期：2017-10-09 00:00:00

abstract：:F-actins are semi-flexible polyelectrolytes and can be assembled into a large polymer-actin complex with polymorphism through electrostatic interaction with polycations. This study investigates the structural phase behavior and the growth of polymer-actin complexes in terms of its longitudinal and lateral sizes in var...

journal_title：Biomacromolecules

authors： Kwon HJ,Kakugo A,Shikinaka K,Osada Y,Gong JP

更新日期：2005-11-01 00:00:00

abstract：:A new route for the design of renewable hydrogels is presented. The soluble waste from masonite production was isolated, fractionized, and upgraded. The resulting hemicellulose rich fraction was alkenyl-functionalized and used in the preparation of covalently cross-linked hydrogels capable of sustained release of inco...

journal_title：Biomacromolecules

authors： Albertsson AC,Voepel J,Edlund U,Dahlman O,Söderqvist-Lindblad M

更新日期：2010-05-10 00:00:00

abstract：:The recombinant amylosucrase from Neisseria polysaccharea was used to glucosylate glycogen particles in vitro in the presence of sucrose as the glucosyl donor. The morphology and structure of the resulting insoluble products were shown to strongly depend on the initial sucrose/glycogen weight ratio. For the lower rati...

journal_title：Biomacromolecules

authors： Putaux JL,Potocki-Véronèse G,Remaud-Simeon M,Buleon A

更新日期：2006-06-01 00:00:00

abstract：:Liver glycogen, a highly branched polymer of glucose, is important for maintaining blood-glucose homeostasis. It was recently shown that db/db mice, a model for Type 2 diabetes, are unable to form the large composite glycogen α particles present in normal, healthy mice. In this study, the structure of healthy mouse-li...

journal_title：Biomacromolecules

authors： Sullivan MA,Aroney ST,Li S,Warren FJ,Joo JS,Mak KS,Stapleton DI,Bell-Anderson KS,Gilbert RG

更新日期：2014-02-10 00:00:00

abstract：:The influence of 2,2,6,6-tetrametylpiperidine-1-oxyl (TEMPO)-mediated oxidation of wood cellulose and the mechanical disintegration of oxidized cellulose in water on degree of polymerization determined by viscosity measurement (DP(v)) and the apparent length of the TEMPO-oxidized cellulose nanofibrils (TOCNs) was inve...

journal_title：Biomacromolecules

authors： Shinoda R,Saito T,Okita Y,Isogai A

更新日期：2012-03-12 00:00:00

abstract：:In this paper we propose a detailed analysis of structural and morphological properties of two poly-L-lysine (PLL)-based transfection formulations, PLL/DNA and pegylated PLL (PLL-g-PEG)/DNA, by means of atomic force microscopy (AFM) and transmission electron microscopy (TEM). Comparing PLL-g-PEG/DNA with PLL/DNA polyp...

journal_title：Biomacromolecules

authors： Stanić V,Arntz Y,Richard D,Affolter C,Nguyen I,Crucifix C,Schultz P,Baehr C,Frisch B,Ogier J

更新日期：2008-07-01 00:00:00

abstract：:Although micelles are commonly used for drug delivery purposes, their long-term fate is often unknown due to photobleaching of the fluorescent labels or the use of toxic materials. Here, we present a metal-free, nontoxic, nonbleaching, fluorescent micelle that can address these shortcomings. A simple, yet versatile, p...

journal_title：Biomacromolecules

authors： Zaquen N,Lu H,Chang T,Mamdooh R,Lutsen L,Vanderzande D,Stenzel M,Junkers T

更新日期：2016-12-12 00:00:00

abstract：:The development of sustainable materials by employing natural and nontoxic resources has been attracting much attention over the previous years. In this work, we discuss for the first time the chemical combination between resorcinol diglycidyl ether (RDGE), an aromatic biobased thermosetting monomer, and polyhydroxybu...

journal_title：Biomacromolecules

authors： Cantarutti C,Dinu R,Mija A

更新日期：2020-08-10 00:00:00

abstract：:Two linear alpha-(1,4)-D-glucans substrates, of degrees of polymerization DP approximately 150 and 6000, were exposed to maize starch-branching enzyme IIa (mSBEIIa) in vitro. The resulting branched alpha-glucans and their constituent chains (obtained by debranching) were analyzed by nuclear magnetic resonance (NMR) an...

journal_title：Biomacromolecules

authors： Hernández JM,Gaborieau M,Castignolles P,Gidley MJ,Myers AM,Gilbert RG

更新日期：2008-03-01 00:00:00

abstract：:Tumorigenic cell behaviors can be suppressed or enhanced by their physicochemical environment. As a first step toward developing materials that allow tumorigenic behaviors to be observed and manipulated, we cultured related MCF10 breast cell lines on fibers composed of the Drosophila protein Ultrabithorax (Ubx). These...

journal_title：Biomacromolecules

authors： Hsiao HC,Santos A,Howell DW,Patterson JL,Fuchs-Young RS,Bondos SE

更新日期：2016-11-14 00:00:00

abstract：:Poly(lactide)-block-poly(ethylene oxide)-block-poly(lactide) (PLA-PEO-PLA) triblock copolymers are known to form physical hydrogels in water as a result of the polymer's amphiphilicity. Their mechanical properties, biocompatibility, and biodegradability have made them attractive for use as soft tissue scaffolds. Howev...

journal_title：Biomacromolecules

authors： Sanabria-DeLong N,Crosby AJ,Tew GN

更新日期：2008-10-01 00:00:00

abstract：:Chitosan is a linear cationic biopolymer composed of glucosamine and N-acetyl-glucosamine that is only soluble in acidic aqueous solutions and precipitates when neutralized. However, it was recently discovered that chitosan dissolved in solutions containing glycerol phosphate was soluble at near neutral pH and produce...

journal_title：Biomacromolecules

authors： Filion D,Lavertu M,Buschmann MD

更新日期：2007-10-01 00:00:00

abstract：:Gastric mucin, a high molecular weight glycoprotein, is responsible for providing the gel-forming properties and protective function of the gastric mucus layer. Bulk rheology measurements in the linear viscoelastic regime show that gastric mucin undergoes a pH-dependent sol-gel transition from a viscoelastic solution ...

journal_title：Biomacromolecules

authors： Celli JP,Turner BS,Afdhal NH,Ewoldt RH,McKinley GH,Bansil R,Erramilli S

更新日期：2007-05-01 00:00:00

abstract：:There has been little study on the effect of composition or molecular weight on the biodegradation rate of photo-cross-linked biodegradable aliphatic polyesters though such information is important for tissue engineering scaffolds. We have synthesized a new series of photopolymerizable linear poly(epsilon-caprolactone...

journal_title：Biomacromolecules

authors： Shen JY,Pan XY,Lim CH,Chan-Park MB,Zhu X,Beuerman RW

更新日期：2007-02-01 00:00:00

abstract：:The determination of the collagen and glycosaminoglycan (GAG) contents of native and particularly bioengineered tissues is of considerable interest because the collagen-to-GAG ratio determines the water content of the tissue, which is crucial regarding its mechanical properties. (1)H NMR spectroscopy subsequent to the...

journal_title：Biomacromolecules

authors： Riemer T,Nimptsch A,Nimptsch K,Schiller J

更新日期：2012-07-09 00:00:00

abstract：:Multifunctional and highly biocompatible polyether structures play a key role in shielding liposomes from degradation in the bloodstream, providing also multiple functional groups for further attachment of targeting moieties. In this work hyperbranched polyglycerol ( hbPG) bearing lipids with long alkyl chain anchor a...

journal_title：Biomacromolecules

authors： Wagener K,Worm M,Pektor S,Schinnerer M,Thiermann R,Miederer M,Frey H,Rösch F

更新日期：2018-07-09 00:00:00

abstract：:This paper describes the synthesis and evaluation of a series of multifunctional poly-l-glutamic acid derivatives that can be used as vectors for gene delivery. They readily form polyelectrolyte complexes with DNA, resulting in a reduced surface charge and size of the DNA. The formation of a polymer-DNA complex and th...

journal_title：Biomacromolecules

authors： Dubruel P,Dekie L,Schacht E

更新日期：2003-09-01 00:00:00

abstract：:Binding interactions between low molecular weight heparin (LMWH) and heparin-binding peptides (HBP) have been applied as a strategy for the assembly of hydrogels that are capable of sequestering growth factors and delivering them in a controlled manner. In this work, the assembly of four-arm star poly(ethylene glycol)...

journal_title：Biomacromolecules

authors： Yamaguchi N,Chae BS,Zhang L,Kiick KL,Furst EM

更新日期：2005-07-01 00:00:00

abstract：:In this work, we have applied an electrospinning method to control wettability and further hydrophobic modification of a hydrophobic polymer mat of poly(vinylidene fluoride-co-hexafluoropropylene). A correlation between the processing parameters, rheological properties of polymer solutions, and electrospinning ability...

journal_title：Biomacromolecules

authors： Ahmed F,Choudhury NR,Dutta NK,Zannettino A,Knott R

更新日期：2013-11-11 00:00:00

abstract：:The synthesis of core-shell star copolymers via living free radical polymerization provides a convenient route to three-dimensional nanostructures having a poly(ethylene glycol) outer shell, a hydrophilic inner shell bearing reactive functional groups, and a central hydrophobic core. By starting with well-defined line...

journal_title：Biomacromolecules

authors： Fukukawa K,Rossin R,Hagooly A,Pressly ED,Hunt JN,Messmore BW,Wooley KL,Welch MJ,Hawker CJ

更新日期：2008-04-01 00:00:00

abstract：:Photosensitive supramolecular micelles, a combination of intermolecular hydrogen bonds between complementary adenine (A) and uracil (U) groups and a blend of two types of supramolecular polymers, can stably self-assemble into structurally stable, spherical micelles in aqueous solution before and after photoirradiation...

journal_title：Biomacromolecules

authors： Abebe Alemayehu Y,Tewabe Gebeyehu B,Cheng CC

更新日期：2019-12-09 00:00:00

abstract：:A strategy to manipulate the disulfide bond breaking triggered unfolding, and subsequently assembly of human serum albumin (HSA) in a lipophilic drug-dependent manner is present. In this study, the hydrophobic region, a molecular switch of the HSA, was regulated to form HSA-paclitaxel (HSA-PTX) nanoparticles by a faci...

journal_title：Biomacromolecules

authors： Gong G,Xu Y,Zhou Y,Meng Z,Ren G,Zhao Y,Zhang X,Wu J,Hu Y

更新日期：2012-01-09 00:00:00

abstract：:A new mathematical model is presented for the analysis of the substituent distribution in the polymer chain of polysaccharide derivatives. For the first time, the influence of substitution on the reactivity of neighbored monomer units is taken into account. The model was applied to various cellulose and amylose ethers...

journal_title：Biomacromolecules

authors： Mischnick P,Hennig C

更新日期：2001-04-01 00:00:00

abstract：:Photodynamic therapy (PDT) has attracted widespread attention in recent years as a noninvasive and highly selective approach for cancer treatment. We have previously reported a significant increase in the 90-day complete response rate when tumor-bearing mice are treated with the epidermal growth factor receptor (EGFR)...

journal_title：Biomacromolecules

authors： Yan L,Miller J,Yuan M,Liu JF,Busch TM,Tsourkas A,Cheng Z

更新日期：2017-06-12 00:00:00

abstract：:Biobased poly(γ-butyrolactone) (PγBL) as a fully biodegradable and bioabsorbable biomaterial has shown superior properties compared to those of other aliphatic polyesters. It is of great importance to prepare amphiphilic block copolymer containing PγBL block to make ordered nano-objects for biomedical applications suc...

journal_title：Biomacromolecules

authors： Shen Y,Zhang J,Zhao Z,Zhao N,Liu F,Li Z

更新日期：2019-01-14 00:00:00

abstract：:Polymer conjugation increases an enzyme's circulation time and stability for use as a therapeutic agent, but this attachment indubitably affects its properties. Covalent attachment of multiple polyethylene glycol chains with sizes of either 2, 5, 10, or 20 kDa increases the molecular weight and hydrodynamic radius of ...

journal_title：Biomacromolecules

authors： Chiu K,Agoubi LL,Lee I,Limpar MT,Lowe JW Jr,Goh SL

更新日期：2010-12-13 00:00:00

abstract：:This paper describes the synthesis and characterization of a novel organic polymer coating for the prevention of the growth of Pseudomonas aeruginosa on the solid surface of three-dimensional objects. Substrata were encapsulated with polyterpenol thin films prepared from terpinen-4-ol using radio frequency plasma enha...

journal_title：Biomacromolecules

authors： Bazaka K,Jacob MV,Truong VK,Wang F,Pushpamali WA,Wang JY,Ellis AV,Berndt CC,Crawford RJ,Ivanova EP

更新日期：2010-08-09 00:00:00