Genetics and Genomics of Social Behavior in a Chicken Model.

Abstract:

:The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identify genes for social reinstatement, a social and anxiety-related behavior. A total of 24 social reinstatement QTL were identified and overlaid with over 600 eQTL obtained from the same birds using hypothalamic tissue. Correlations between overlapping QTL and eQTL indicated five strong candidate genes, with the gene TTRAP being strongly significantly correlated with multiple aspects of social reinstatement behavior, as well as possessing a highly significant eQTL.

journal_name

Genetics

journal_title

Genetics

authors

Johnsson M,Henriksen R,Fogelholm J,Höglund A,Jensen P,Wright D

doi

10.1534/genetics.118.300810

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

209-221

issue

1

eissn

0016-6731

issn

1943-2631

pii

genetics.118.300810

journal_volume

209

pub_type

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