Abstract:
:The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identify genes for social reinstatement, a social and anxiety-related behavior. A total of 24 social reinstatement QTL were identified and overlaid with over 600 eQTL obtained from the same birds using hypothalamic tissue. Correlations between overlapping QTL and eQTL indicated five strong candidate genes, with the gene TTRAP being strongly significantly correlated with multiple aspects of social reinstatement behavior, as well as possessing a highly significant eQTL.
journal_name
Geneticsjournal_title
Geneticsauthors
Johnsson M,Henriksen R,Fogelholm J,Höglund A,Jensen P,Wright Ddoi
10.1534/genetics.118.300810subject
Has Abstractpub_date
2018-05-01 00:00:00pages
209-221issue
1eissn
0016-6731issn
1943-2631pii
genetics.118.300810journal_volume
209pub_type
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