Abstract:
:In Arabidopsis thaliana, DICER-LIKE 1 and DICER-LIKE 3 are involved in the generation of small RNAs. Double mutants between dicer-like 1 and dicer-like 3 exhibit a delay in flowering that is caused by increased expression of the floral repressor FLOWERING LOCUS C. This delayed-flowering phenotype is similar to that of autonomous-pathway mutants, and the flowering delay can be overcome by vernalization.
journal_name
Geneticsjournal_title
Geneticsauthors
Schmitz RJ,Hong L,Fitzpatrick KE,Amasino RMdoi
10.1534/genetics.107.070649subject
Has Abstractpub_date
2007-06-01 00:00:00pages
1359-62issue
2eissn
0016-6731issn
1943-2631pii
genetics.107.070649journal_volume
176pub_type
杂志文章相关文献
GENETICS文献大全abstract::In lytic cycle crosses with Red-Gam-lambda phage, particles were examined that had undergone an Int-mediated exchange. It was assumed that this exchange dimerized the circular lambda, making it packageable. Among these Int-mediated recombinants, particles were identified that had, in addition, enjoyed a close double e...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract::Centromere H3 proteins (CenH3's) are variants of histone H3 specialized for packaging centromere DNA. Unlike canonical H3, which is among the most conserved of eukaryotic proteins, CenH3's are rapidly evolving, raising questions about orthology and conservation of function across species. To gain insight on CenH3 evol...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.106.062794
更新日期:2006-11-01 00:00:00
abstract::An article by Singh and colleagues in this issue of GENETICS quantifies variation in recombination rate across a small region of the Drosophila melanogaster genome, providing an opportunity for instructors of genetics to introduce or reinforce important concepts such as recombination and recombination rate variation, ...
journal_title:Genetics
pub_type: 评论,杂志文章
doi:10.1534/genetics.113.150771
更新日期:2013-06-01 00:00:00
abstract::Previous work showed that C. elegans gon-14 is required for gonadogenesis. Here we report that gon-14 encodes a protein with similarity to LIN-15B, a class B synMuv protein. An extensive region of GON-14 contains blocks of sequence similarity to transposases of the hAT superfamily, but key residues are not conserved, ...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.105.048751
更新日期:2006-02-01 00:00:00
abstract::The effect of nonhomologous DNA sequences at one or both sides of short genetic intervals on recombination within that interval was investigated, using an interplasmidic recombination system in Escherichia coli K-12. The recombining plasmids were derivatives of pBR322 and pACYC184, which share a 1330-nucleotide sequen...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract::Evolution through natural selection suggests unnecessary genes are lost. We observed that the yeast Candida glabrata lost the gene encoding a phosphate-repressible acid phosphatase (PHO5) present in many yeasts including Saccharomyces cerevisiae. However, C. glabrata still had phosphate starvation-inducible phosphatas...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.110.120824
更新日期:2010-11-01 00:00:00
abstract::We previously identified a transcriptional regulatory element, which we call NRE(DIT), that is required for repression of the sporulation-specific genes, DIT1 and DIT2, during vegetative growth of Saccharomyces cerevisiae. Repression through this element is dependent on the Ssn6-Tup1 corepressor. In this study, we sho...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::Genetic material sequenced from ancient samples is revolutionizing our understanding of the recent evolutionary past. However, ancient DNA is often degraded, resulting in low coverage, error-prone sequencing. Several solutions exist to this problem, ranging from simple approach, such as selecting a read at random for ...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.117.300448
更新日期:2018-01-01 00:00:00
abstract::We have studied the deletion of inverted repeats cloned into the EcoRI site within the CAT gene of plasmid pBR325. A cloned inverted repeat constitutes a palindrome that includes both EcoRI sites flanking the insert. In addition, the two EcoRI sites represent direct repeats flanking a region of palindromic symmetry. A...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract::Fifty-eight isochromosomal lines sampled from two natural populations of Drosophila pseudoobscura in California and one from Bogota, Colombia, were examined using four-cutter restriction mapping. A 4.6-kb region of the xanthine dehydrogenase locus was probed and 66 of 135 restriction sites scored were polymorphic. Thi...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::We consider a population that adapts to a gradually changing environment. Our aim is to describe how ecological and genetic factors combine to determine the genetic basis of adaptation. Specifically, we consider the evolution of a polygenic trait that is under stabilizing selection with a moving optimum. The ecologica...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.109.106195
更新日期:2009-12-01 00:00:00
abstract::Bacteriophage T4 cytosine-containing DNA is cleaved at a single site by the restriction endonuclease, Bam H1. The site lies within the late region of the T4 genome, close to, or within, gene 8, one of the structural genes of the phage particle baseplate. ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1979-10-01 00:00:00
abstract::As a genetic mutation is passed down across generations, it distinguishes those genomes that have inherited it from those that have not, providing a glimpse of the genealogical tree relating the genomes to each other at that site. Statistical summaries of genetic variation therefore also describe the underlying geneal...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.120.303253
更新日期:2020-07-01 00:00:00
abstract::The Saccharomyces cerevisiae SEN1 gene codes for a nuclear-localized superfamily I helicase. SEN1 is an ortholog of human SETX (senataxin), which has been implicated in the neurological disorders ataxia-ocular apraxia type 2 and juvenile amyotrophic lateral sclerosis. Pleiotropic phenotypes conferred by sen1 mutations...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.109.110031
更新日期:2010-01-01 00:00:00
abstract::The range of possible gene interactions in a multilocus model of a complex inherited disease is studied by exploring genotype-specific risks subject to the constraint that the allele frequencies and marginal risks are known. We quantify the effect of gene interactions by defining the interaction ratio, CR=KR/KRI, wher...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.110.119008
更新日期:2010-12-01 00:00:00
abstract::In the yeast Saccharomyces cerevisiae, rim1, 8, 9, or 13 mutations cause four phenotypes: poor growth at low temperature, altered colony morphology, inefficient sporulation due to reduced expression of the meiotic activator IME1, and, as shown here, defective invasive growth. In this report, we have determined the rel...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Zymograms were analyzed of a number of Triticum aestivum derivatives which incorporated a segment of the Aegilops umbellulata chromosome bearing resistance to leaf rust. Evidence has been presented which suggests that genes involved in the production of two peroxidases and a single peptidase are located on the short a...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1972-09-01 00:00:00
abstract::The infinite-sites model with no recombination is extended to include mutations that affect electrophoretic mobility. The model allows the effect of a single-site mutation to have a continuous effect on mobility. Formulae are obtained for the variance of electrophoretic mobility of alleles after an arbitrary lenght of...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1979-06-01 00:00:00
abstract::We analyzed the dynamics of transposable elements (TEs) according to Wright's island and continent-island models, assuming that selection tends to counter the deleterious effects of TEs. We showed that migration between host populations has no impact on either the existence or the stability of the TE copy number equil...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.104.032243
更新日期:2005-01-01 00:00:00
abstract::Segregation distorter (SD) chromosomes are preferentially transmitted to offspring from heterozygous SD/SD(+) males owing to the induced dysfunction of the SD(+)-bearing sperm. This phenomenon involves at least two major loci: the Sd locus whose presence is necessary for distortion to occur and the Rsp locus which act...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::Regulation of transcription can be a complex process in which many cis- and trans-interactions determine the final pattern of expression. Among these interactions are trans-interactions mediated by the pairing of homologous chromosomes. These trans-effects are wide ranging, affecting gene regulation in many species an...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.111.133231
更新日期:2011-11-01 00:00:00
abstract::The segregation distortion phenomenon occurs in Drosophila melanogaster males carrying an SD second chromosome and an SD+ homolog. In such males the SD chromosome is transmitted to the progeny more frequently than the expected 50% because of an abnormal differentiation of the SD+-bearing sperms. Three major loci are i...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::PGM plays a central role in the glycolytic pathway at the branch point leading to glycogen metabolism and is highly polymorphic in allozyme studies of many species. We have characterized the nucleotide diversity across the Pgm gene in Drosophila melanogaster and D. simulans to investigate the role that protein polymor...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::Very few mutations derived from Mutator maize lines have been studied at the molecular level. The variety of Mu elements that can induce mutations, the relative frequency of mutant induction by insertion of a given class of Mu elements or by a Mu-induced genomic rearrangement, a possible intragenic insertion site spec...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::The process of close recombinant formation in bacteriophage T5 crosses has been studied by examining the structure of internal heterozygotes (HETs), the immediate products of recombination events. The T5 system was chosen because it permits the study of internal heterozygotes exclusively, thus avoiding the ambiguities...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1980-09-01 00:00:00
abstract::We consider inference for demographic models and parameters based upon postprocessing the output of an MCMC method that generates samples of genealogical trees (from the posterior distribution for a specific prior distribution of the genealogy). This approach has the advantage of taking account of the uncertainty in t...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.107.071910
更新日期:2007-09-01 00:00:00
abstract::Natural populations of Daphnia magna have been found which are polymorphic for electrophoretic variants of supernatant malic dehydrogenase, esterase, and alkaline phosphatase. Using these enzyme variants as genetic markers it has been possible to demonstrate the absence of recombination during parthenogenetic reproduc...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1972-08-01 00:00:00
abstract::We study the mechanisms that guide the formation and maintenance of the highly ordered actin-myosin cytoskeleton in striated muscle. The UNC-82 kinase of Caenorhabditis elegans is orthologous to mammalian kinases ARK5/NUAK1 and SNARK/NUAK2. UNC-82 localizes to the M-line, and is required for proper organization of thi...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.116.193029
更新日期:2017-03-01 00:00:00
abstract::Detecting and quantifying the differences in individual genomes (i.e., genotyping), plays a fundamental role in most modern bioinformatics pipelines. Many scientists now use reduced representation next-generation sequencing (NGS) approaches for genotyping. Genotyping diploid individuals using NGS is a well-studied fie...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.118.301468
更新日期:2018-11-01 00:00:00
abstract::In meiosis, multiple different DNA sequence motifs help to position homologous recombination at hotspots in the genome. How do the seemingly disparate cis-acting regulatory modules each promote locally the activity of the basal recombination machinery? We defined molecular mechanisms of action for five different hotsp...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.119.302679
更新日期:2019-11-01 00:00:00