A model allowing continuous variation in electrophoretic mobility of neutral alleles.

abstract：:In most eukaryotes, crossovers are not independently distributed along the length of a chromosome. Instead, they appear to avoid close proximity to one another--a phenomenon known as crossover interference. Previously, for three of the five Arabidopsis chromosomes, we measured the strength of interference and suggeste...

journal_title：Genetics

authors： Lam SY,Horn SR,Radford SJ,Housworth EA,Stahl FW,Copenhaver GP

更新日期：2005-06-01 00:00:00

abstract：:Using a new model of isoalleles, extensive Monte Carlo experiments were performed to examine the pattern of allelic distribution in a finite population. In this model it was assumed that the set of allelic states is represented by discrete points on a one-dimensional lattice and that change of state by mutation occurs...

journal_title：Genetics

authors： Ohta T,Kimura M

更新日期：1974-03-01 00:00:00

abstract：:Hepatic glucocorticoid receptor binding activity was measured in A/J, C57BL/6J, their F1 reciprocal crosses and their F1 recombinant inbred (RI) lines. The glucocorticoid binding capacity was measured in Hepes buffer and Hepes buffer plus dithiothreitol (DTT). The A/J parental strain showed higher levels, and a greate...

journal_title：Genetics

authors： Liu SL,Erickson RP

更新日期：1986-07-01 00:00:00

abstract：:Genomic prediction methods based on multiple markers have potential to include nonadditive effects in prediction and analysis of complex traits. However, most developments assume a Hardy-Weinberg equilibrium (HWE). Statistical approaches for genomic selection that account for dominance and epistasis in a general conte...

journal_title：Genetics

authors： Vitezica ZG,Legarra A,Toro MA,Varona L

更新日期：2017-07-01 00:00:00

abstract：:The resistance of rice to its bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo) has both qualitative and quantitative components that were investigated using three near-isogenic line sets for four resistance (R) genes (Xa4, xa5, xa13, and Xa21) and 12 Xoo races. Our results indicate that these two resistan...

journal_title：Genetics

authors： Li ZK,Sanchez A,Angeles E,Singh S,Domingo J,Huang N,Khush GS

更新日期：2001-10-01 00:00:00

abstract：:In Saccharomyces cerevisiae, genes located at the telomeres and the HM loci are subject to transcriptional silencing. Here, we report results of screening a Gal4 DNA-binding domain hybrid library for proteins that cause silencing when targeted to a silencer-defective HMR locus. ...

journal_title：Genetics

authors： Andrulis ED,Zappulla DC,Alexieva-Botcheva K,Evangelista C,Sternglanz R

更新日期：2004-01-01 00:00:00

abstract：:A large number of arginine-requiring mutants of Neurospora was isolated, using a strain already partially impaired in an enzyme of the pathway. Among the mutants, all previously described loci, except one, were represented, and several new loci were defined and mapped. Four groups of mutants were of particular interes...

journal_title：Genetics

authors： Davis RH

更新日期：1979-11-01 00:00:00

abstract：:We have used mutational and revertant analysis to study the elements of the 54-nucleotide COX2 5'-untranslated leader involved in translation initiation in yeast mitochondria and in activation by the COX2 translational activator. Pet111p. We generated a collection of mutants with substitutions spanning the entire COX2...

journal_title：Genetics

authors： Dunstan HM,Green-Willms NS,Fox TD

更新日期：1997-09-01 00:00:00

abstract：:Restriction map variation in two 5-6-kb chloroplast DNA regions of five diploid Aegilops species in the section Sitopsis and two wild tetraploid wheats, Triticum dicoccoides and Triticum araraticum, was investigated with a battery of four-cutter restriction enzymes. A single accession each of Triticum durum, Triticum ...

journal_title：Genetics

authors： Miyashita NT,Mori N,Tsunewaki K

更新日期：1994-07-01 00:00:00

abstract：:Pathogen resistance is an ecologically important phenotype increasingly well understood at the molecular genetic level. In this article, we examine levels of avrRpt2-dependent resistance and Rps2 locus DNA sequence variability in a worldwide sample of 27 accessions of Arabidopsis thaliana. The rooted parsimony tree of...

journal_title：Genetics

authors： Mauricio R,Stahl EA,Korves T,Tian D,Kreitman M,Bergelson J

更新日期：2003-02-01 00:00:00

abstract：:The organization of the mitochondrial genome in plants is not well understood. In maize mitochondrial DNA (mtDNA) several subgenomic circular molecules as well as an abundant fraction of linear molecules have been seen by electron microscopy. It has been hypothesized that the circular molecules are the genetic entitie...

journal_title：Genetics

authors： Levy AA,André CP,Walbot V

更新日期：1991-06-01 00:00:00

abstract：:Yeast cells deficient in the transcriptional activator Imp2p are viable, but display marked hypersensitivity to a variety of oxidative agents. We now report that imp2 null mutants are also extremely sensitive to elevated levels of the monovalent ions, Na+ and Li+, as well as to the divalent ions Ca2+, Mn2+, Zn2+, and ...

journal_title：Genetics

authors： Masson JY,Ramotar D

更新日期：1998-06-01 00:00:00

abstract：:Selection of Gl-Sb coupling heterozygotes was carried out for more than one hundred generations commencing with six independent lines drawn from a common base population. Population sizes were eight, sixteen and forty-eight parents per generation. The effect of natural selection on recombination value was measured by ...

journal_title：Genetics

authors： Kidwell MG

更新日期：1972-03-01 00:00:00

abstract：:A point connecting a pair of homologous regions of DNA duplexes moves along the homology in a reaction intermediate of the homologous recombination. Formulating this movement as a random walk, we were previously successful at explaining the dependence of the recombination frequency on the homology length. Recently, th...

journal_title：Genetics

authors： Fujitani Y,Kobayashi I

更新日期：1999-12-01 00:00:00

abstract：:Selection coefficients and segregation parameters have been estimated in 18 randomly chosen lines carrying wild X chromosomes on the cn bw genetic background. Each line was studied in replicated crosses of four types, with approximately 100 replications per line per cross. Crosses in which male X chromosomes differed ...

journal_title：Genetics

authors： Curtsinger JW

更新日期：1984-12-01 00:00:00

abstract：:Polyploidy has occurred throughout the evolutionary history of all eukaryotes and is extremely common in plants. Reunification of the evolutionarily divergent genomes in allopolyploids creates regulatory incompatibilities that must be reconciled. Here we report genomewide gene expression analysis of Arabidopsis synthe...

journal_title：Genetics

authors： Wang J,Tian L,Lee HS,Wei NE,Jiang H,Watson B,Madlung A,Osborn TC,Doerge RW,Comai L,Chen ZJ

更新日期：2006-01-01 00:00:00

abstract：:It is well known that an allele causing increased recombination is expected to proliferate as a result of genetic drift in a finite population undergoing selection, without requiring other mechanisms. This is supported by recent simulations apparently demonstrating that, in small populations, drift is more important t...

journal_title：Genetics

authors： Iles MM,Walters K,Cannings C

更新日期：2003-12-01 00:00:00

abstract：:DnaB is the helicase associated with the DNA polymerase III replication fork in Escherichia coli. Previously we observed that the dnaB107(ts) mutation, at its permissive temperature, greatly stimulated deletion events at chromosomal tandem repeats. This stimulation required recA, which suggests a recombinational mecha...

journal_title：Genetics

authors： Saveson CJ,Lovett ST

更新日期：1999-05-01 00:00:00

abstract：:Evolutionary forces shape patterns of genetic diversity within populations and contribute to phenotypic variation. In particular, recurrent positive selection has attracted significant interest in both theoretical and empirical studies. However, most existing theoretical models of recurrent positive selection cannot e...

journal_title：Genetics

authors： Uricchio LH,Hernandez RD

更新日期：2014-05-01 00:00:00

abstract：:Cell surface immunoglobulin superfamily (IgSF) proteins play important roles in the development and function of the nervous system . Here we define the role of a Caenorhabditis elegans IgSF protein, RIG-3, in the function of the AVA command interneuron. This study reveals that RIG-3 regulates the abundance of the glut...

journal_title：Genetics

authors： Bhardwaj A,Pandey P,Babu K

更新日期：2020-01-01 00:00:00

abstract：:High-throughput sequencing and bioinformatic techniques have enhanced classical genetic analysis and are essential methods for geneticists. Tsukamoto and colleagues use numerous genomic and bioinformatics methods to explore the role of ribonucleoprotein complexes in regulating oocyte meiotic maturation, which is the t...

journal_title：Genetics

authors： Thurtle-Schmidt D,Lo TW

更新日期：2018-07-01 00:00:00

abstract：:Availability of animal protein for human consumption is very low in the developing countries mainly because of low productivity of existing livestock; ways and means to improve productivity through breeding are discussed and some basic issues requiring further research pointed out. ...

journal_title：Genetics

authors： Rendel J

更新日期：1974-09-01 00:00:00

abstract：:Some populations of maize's closest relatives, the annual teosintes of Mexico, are unreceptive to maize pollen. When present in the pistil (silk and ovary) a number of maize genes discriminate against or exclude pollen not carrying the same allele. An analogous gene Tcb1-s was found in some teosinte populations but no...

journal_title：Genetics

authors： Kermicle JL

更新日期：2006-01-01 00:00:00

abstract：:Transmission ratio distortion (TRD) is the departure from the expected genotypic frequencies under Mendelian inheritance. This departure can be due to multiple physiological mechanisms during gametogenesis, fertilization, fetal and embryonic development, and early neonatal life. Although a few TRD loci have been repor...

journal_title：Genetics

authors： Casellas J,Gularte RJ,Farber CR,Varona L,Mehrabian M,Schadt EE,Lusis AJ,Attie AD,Yandell BS,Medrano JF

更新日期：2012-05-01 00:00:00

abstract：:The supramolecular striatin-interacting phosphatases and kinases (STRIPAK) complex is conserved from yeast to human, and regulates a variety of key biological processes. In animals, this complex consists of the scaffold protein striatin, the protein phosphatase 2A, and kinases, such as germinal center kinase (GCK) III...

journal_title：Genetics

authors： Radchenko D,Teichert I,Pöggeler S,Kück U

更新日期：2018-09-01 00:00:00

abstract：:Mutations in ilvO, the operator site for operon A of the ilv region of E. coli K-12, are reported to cause a cis dominant derepression of the operon A gene products and to map between ilvC and ilvA. Studies reported here demonstrate that the F25 episome which does not carry the region between ilvC and ilvA but only il...

journal_title：Genetics

authors： Cohen BM,Jones EW

更新日期：1976-06-01 00:00:00

abstract：:The extent to which epistasis contributes to adaptation, population differentiation, and speciation is a long-standing and important problem in evolutionary genetics. Using recombinant inbred (RI) lines of Arabidopsis thaliana grown under natural field conditions, we have examined the genetic architecture of fitness-c...

journal_title：Genetics

authors： Malmberg RL,Held S,Waits A,Mauricio R

更新日期：2005-12-01 00:00:00

abstract：:The double-strand break repair models for homologous recombination propose that a double-strand break in a duplex DNA segment is repaired by gene conversion copying a homologous DNA segment. This is a type of conservative recombination, or two-progeny recombination, which generates two duplex DNA segments from two dup...

journal_title：Genetics

authors： Yokochi T,Kusano K,Kobayashi I

更新日期：1995-01-01 00:00:00

abstract：:A sulfonamide-resistant mutant of pneumococcus, sulr-c, displays a genetic instability, regularly segregating to wild type. DNA extracts of derivatives of the strain possess transforming activities for both the mutant and wild-type alleles, establishing that the strain is a partial diploid. The linkage of sulr-c to st...

journal_title：Genetics

authors： Ledbetter ML,Hotchkiss RD

更新日期：1975-08-01 00:00:00

abstract：:Parameters of continuous distributions of effects and rates of spontaneous mutation for relative viability in Drosophila are estimated by maximum likelihood from data of two published experiments on accumulation of mutations on protected second chromosomes. A model of equal mutant effects gives a poor fit to the data ...

journal_title：Genetics

authors： Keightley PD

更新日期：1994-12-01 00:00:00