Genetic change of recobination value in Drosophila melanogaster. II. Simulated natural selection.

Abstract:

:Selection of Gl-Sb coupling heterozygotes was carried out for more than one hundred generations commencing with six independent lines drawn from a common base population. Population sizes were eight, sixteen and forty-eight parents per generation. The effect of natural selection on recombination value was measured by sampling and testing females at varying intervals of time. There was a significant reduction in percentage recombination between Gl and Sb from fifteen to a level between five and ten in four out of six of the original lines. In most cases this reduction occurred rather rapidly after the initiation of the experiment. In the remaining two lines there was no significant decrease in recombination value; there was, however, a significant increase in at least one subline of this group. The rapid rate of change of recombination value is most readily explained by the presence of a recombination modifying gene which is linked to the modified region. Genetic random drift was again shown to have an important effect on changes in recombination value in small populations. High recombination was almost completely recessive to low recombination in the one case examined. Lethal genes were fixed in sheltered regions of unmarked third chromosomes in five lines or sublines. These results are discussed in relation to the mode of development of permanent heterozygosity in some species of plants.

journal_name

Genetics

journal_title

Genetics

authors

Kidwell MG

subject

Has Abstract

pub_date

1972-03-01 00:00:00

pages

433-43

issue

3

eissn

0016-6731

issn

1943-2631

journal_volume

70

pub_type

杂志文章

相关文献

GENETICS文献大全
  • Complex epistasis for Dobzhansky-Muller hybrid incompatibility in solanum.

    abstract::We examined the prevalence of interactions between pairs of short chromosomal regions from one species (Solanum habrochaites) co-introgressed into a heterospecific genetic background (Solanum lycopersicum). Of 105 double introgression line (DIL) families generated from a complete diallele combination of 15 chromosomal...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.108.095679

    authors: Moyle LC,Nakazato T

    更新日期:2009-01-01 00:00:00

  • The ribosomes of Drosophila. II. Studies on intraspecific variation.

    abstract::Electrophoretic comparisons of 40S and 55S ribosomal subunit proteins from 18 strains of Drosophila melanogaster revealed the virtual absence of allelic variation. More detailed two-dimensional studies on the large subunit proteins in 6 of the strains demonstrated additional complexity but still no interstrain variati...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Berger EM,Weber L

    更新日期:1974-12-01 00:00:00

  • Orthogonal Estimates of Variances for Additive, Dominance, and Epistatic Effects in Populations.

    abstract::Genomic prediction methods based on multiple markers have potential to include nonadditive effects in prediction and analysis of complex traits. However, most developments assume a Hardy-Weinberg equilibrium (HWE). Statistical approaches for genomic selection that account for dominance and epistasis in a general conte...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.116.199406

    authors: Vitezica ZG,Legarra A,Toro MA,Varona L

    更新日期:2017-07-01 00:00:00

  • Interactions of liguleless1 and liguleless2 function during ligule induction in maize.

    abstract::The maize ligule is an adaxial membranous structure on the leaf that develops at the boundary of the sheath and blade. The ligule and the associated auricle are dispensable structures, amenable to genetic manipulation. We present here a genetic analysis of liguleless1 (lg1) and liguleless2 (lg2), the two genes known t...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Harper L,Freeling M

    更新日期:1996-12-01 00:00:00

  • Estimating the time to the most recent common ancestor for the Y chromosome or mitochondrial DNA for a pair of individuals.

    abstract::Bayesian posterior distributions are obtained for the time to the most recent common ancestor (MRCA) for a nonrecombining segment of DNA (such as the nonpseudoautosomal arm of the Y chromosome or the mitochondrial genome) for two individuals given that they match at k out of n scored markers. We argue that the distrib...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Walsh B

    更新日期:2001-06-01 00:00:00

  • Regulation of mating and meiosis in yeast by the mating-type region.

    abstract::A supposed sporulation-deficient mutation of Saccharomyces cerevisiae is found to affect mating in haploids and in diploids, and to be inseparable from the mating-type locus by recombination. The mutation is regarded as a defective a allele and is designated a*. This is confirmed by its dominance relations in diploids...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Kassir Y,Simchen G

    更新日期:1976-02-01 00:00:00

  • Phylogenies of central element proteins reveal the dynamic evolutionary history of the mammalian synaptonemal complex: ancient and recent components.

    abstract::During meiosis, the stable pairing of the homologous chromosomes is mediated by the assembly of the synaptonemal complex (SC). Its tripartite structure is well conserved in Metazoa and consists of two lateral elements (LEs) and a central region (CR) that in turn is formed by several transverse filaments (TFs) and a ce...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.113.156679

    authors: Fraune J,Brochier-Armanet C,Alsheimer M,Benavente R

    更新日期:2013-11-01 00:00:00

  • Genetics of glucocorticoid receptor levels in recombinant inbred lines of mice.

    abstract::Hepatic glucocorticoid receptor binding activity was measured in A/J, C57BL/6J, their F1 reciprocal crosses and their F1 recombinant inbred (RI) lines. The glucocorticoid binding capacity was measured in Hepes buffer and Hepes buffer plus dithiothreitol (DTT). The A/J parental strain showed higher levels, and a greate...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Liu SL,Erickson RP

    更新日期:1986-07-01 00:00:00

  • Loss of Drosophila melanogaster p21-activated kinase 3 suppresses defects in synapse structure and function caused by spastin mutations.

    abstract::Microtubules are dynamic structures that must elongate, disassemble, and be cleaved into smaller pieces for proper neuronal development and function. The AAA ATPase Spastin severs microtubules along their lengths and is thought to regulate the balance between long, stable filaments and shorter fragments that seed exte...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.111.130831

    authors: Ozdowski EF,Gayle S,Bao H,Zhang B,Sherwood NT

    更新日期:2011-09-01 00:00:00

  • Insight into the RNA Exosome Complex Through Modeling Pontocerebellar Hypoplasia Type 1b Disease Mutations in Yeast.

    abstract::Pontocerebellar hypoplasia type 1b (PCH1b) is an autosomal recessive disorder that causes cerebellar hypoplasia and spinal motor neuron degeneration, leading to mortality in early childhood. PCH1b is caused by mutations in the RNA exosome subunit gene, EXOSC3 The RNA exosome is an evolutionarily conserved complex, con...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.116.195917

    authors: Fasken MB,Losh JS,Leung SW,Brutus S,Avin B,Vaught JC,Potter-Birriel J,Craig T,Conn GL,Mills-Lujan K,Corbett AH,van Hoof A

    更新日期:2017-01-01 00:00:00

  • Alleles of the hotspot cog are codominant in effect on recombination in the his-3 region of Neurospora.

    abstract::There are two naturally occurring functional alleles of the recombination hotspot cog, which is located 3.5 kb from the his-3 locus of Neurospora crassa. The presence of the cog+ allele in a cross significantly increases recombination in the his-3 region compared to a cross homozygous for the cog allele. Data obtained...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.103.025080

    authors: Yeadon PJ,Bowring FJ,Catcheside DE

    更新日期:2004-07-01 00:00:00

  • Recombination between chromosomal IS200 elements supports frequent duplication formation in Salmonella typhimurium.

    abstract::Spontaneous tandem chromosomal duplications are common in populations of Escherichia coli and Salmonella typhimurium. They range in frequency for a given locus from 10(-2) to 10(-4) and probably form by RecA-dependent unequal sister strand exchanges between repetitive sequences in direct order. Certain duplications ha...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Haack KR,Roth JR

    更新日期:1995-12-01 00:00:00

  • Intragenic Suppression at the b2 Locus in ASCOBOLUS IMMERSUS. II. Characteristics of the Mutations in Groups A and E.

    abstract::The present report is a study of 60 intragenic suppressors located in the A or E group of the b2 spore-color locus of Ascobolus immersus. The frameshift nature of the suppressors was shown by 19 combinations of plus and minus suppressor mutations. The location of the mutation sites on the genetic map of group A was de...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Leblon G

    更新日期:1979-08-01 00:00:00

  • Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew.

    abstract::Signaling by receptor tyrosine kinases (RTKs) is critical for a multitude of developmental decisions and processes. Among the molecules known to transduce the RTK-generated signal is the nonreceptor protein tyrosine phosphatase Corkscrew (Csw). Previously, Csw has been demonstrated to function throughout the Drosophil...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Firth L,Manchester J,Lorenzen JA,Baron M,Perkins LA

    更新日期:2000-10-01 00:00:00

  • A Class of Genes Affecting B Factor-Regulated Development in SCHIZOPHYLLUM COMMUNE.

    abstract::Twelve mutations affecting nuclear migration, a major developmental phase in Schizophyllum commune, display a complex pattern of complementation and recombination. They are expressed only when a genetic factor controlling this phase of development, the B incompatibility factor, is operative. All twelve mutations are l...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Dubovoy C

    更新日期:1976-03-01 00:00:00

  • Four distinct regulatory regions of the cut locus and their effect on cell type specification in Drosophila.

    abstract::The cut gene in Drosophila is necessary in at least one cell type, the external sensory organs, for proper cell type specification and morphogenesis. It is also expressed in a variety of other tissues, where its function is less well characterized. Previous work has demonstrated that mutations affecting all the tissue...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Liu S,McLeod E,Jack J

    更新日期:1991-01-01 00:00:00

  • Wolbachia infection and cytoplasmic incompatibility in Drosophila species.

    abstract::Forty-one stocks from 30 Drosophila species were surveyed for Wolbachia infection using PCR technology. D. sechellia and two strains of D. auraria were found to be infected and were tested for the expression of cytoplasmic incompatibility, along with D. ananassae and D. melanogaster strains, which are already known to...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Bourtzis K,Nirgianaki A,Markakis G,Savakis C

    更新日期:1996-11-01 00:00:00

  • Autoregulatory functioning of a Drosophila gene product that establish es and maintains the sexually determined state.

    abstract::Sxl appears to head a regulatory gene hierarchy that controls Drosophila sexual dimorphism in response to the X chromosome/autosome balance. Only XXAA cells normally have Sxl(+) activity. It maintains both the female morphogenetic sequence and a level of X-linked dosage-compensated gene expression compatible with dipl...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Cline TW

    更新日期:1984-06-01 00:00:00

  • Dosage effects on gene expression in a maize ploidy series.

    abstract::Previous studies on gene expression in aneuploids revealed numerous trans-acting dosage effects. Segmental aneuploidy of each varied chromosomal region exhibited predominantly inverse effects on several target genes. Here, dosage regulation was examined in a maize (Zea mays L.) ploidy series where the complete genomic...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Guo M,Davis D,Birchler JA

    更新日期:1996-04-01 00:00:00

  • Secondary trisomics and telotrisomics of rice: origin, characterization, and use in determining the orientation of chromosome map.

    abstract::Secondary trisomics and telotrisomics representing the 12 chromosomes of rice were isolated from the progenies of primary trisomics. A large population of each primary trisomic was grown. Plants showing variation in gross morphology compared to the primary trisomics and disomic sibs were selected and analyzed cytologi...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Singh K,Multani DS,Khush GS

    更新日期:1996-05-01 00:00:00

  • Bromodeoxyuridine-induced mutations in synchronous Chinese hamster cells: temporal induction of 6-thioguanine and ouabain resistance during DNA replication.

    abstract::Mutations were induced in synchronous Chinese hamster cells by bromodeoxyuridine (BUdR) incorporated into cells for one-hour periods in the cell cycle. There was a very pronounced temporal dependence during the first half of the DNA synthesis period for the induction of damage leading to 6-thioguanine (6TG) and ouabai...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Burki HJ,Aebersold PM

    更新日期:1978-10-01 00:00:00

  • The maize regulatory gene B-Peru contains a DNA rearrangement that specifies tissue-specific expression through both positive and negative promoter elements.

    abstract::The B-Peru allele of the maize b regulatory gene is unusual relative to most b alleles in that it is expressed in the aleurone layer of the seed. It is also expressed in a subset of plant vegetative tissues. Transgenic maize plants containing the B-Peru gene with the first 710 bases of upstream sequence conferred the ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Selinger DA,Lisch D,Chandler VL

    更新日期:1998-06-01 00:00:00

  • Elements causing male crossing over in Drosophila melanogaster.

    abstract::A second chromosome line of Drosophila melanogaster (Symbol: T-007) has previously been shown to be responsible for the induction of male recombination. In the present investigation, the genetic elements responsible for this phenomenon have been partially identified and mapped. A major element (Symbol: Mr, for Male re...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Slatko BE,Hiraizumi Y

    更新日期:1975-10-01 00:00:00

  • The Y chromosome effect on intermale aggression in mice depends on the maternal environment.

    abstract::Two parental strains of laboratory mice, NZB and CBA/H, were chosen for their differences in attack behavior. NZB have higher scores than CBA/H. An effect of the Y chromosome on attack behavior was determined for two maternal environments. Each male was tested once in a dyadic encounter with an A/J male as a standard ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Carlier M,Roubertoux PL,Pastoret C

    更新日期:1991-09-01 00:00:00

  • The impact of environmental heterogeneity on genetic architecture in a wild population of Soay sheep.

    abstract::This work demonstrates that environmental conditions experienced by individuals can shape their development and affect the stability of genetic associations. The implication of this observation is that the environmental response may influence the evolution of traits in the wild. Here, we examined how the genetic archi...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.108.086801

    authors: Robinson MR,Wilson AJ,Pilkington JG,Clutton-Brock TH,Pemberton JM,Kruuk LE

    更新日期:2009-04-01 00:00:00

  • Pervasive sex-linked effects on transcription regulation as revealed by expression quantitative trait loci mapping in lake whitefish species pairs (Coregonus sp., Salmonidae).

    abstract::Mapping of expression quantitative trait loci (eQTL) is a powerful means for elucidating the genetic architecture of gene regulation. Yet, eQTL mapping has not been applied toward investigating the regulation architecture of genes involved in the process of population divergence, ultimately leading to speciation event...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.086306

    authors: Derome N,Bougas B,Rogers SM,Whiteley AR,Labbe A,Laroche J,Bernatchez L

    更新日期:2008-08-01 00:00:00

  • The genetic basis of phenotypic adaptation II: the distribution of adaptive substitutions in the moving optimum model.

    abstract::We consider a population that adapts to a gradually changing environment. Our aim is to describe how ecological and genetic factors combine to determine the genetic basis of adaptation. Specifically, we consider the evolution of a polygenic trait that is under stabilizing selection with a moving optimum. The ecologica...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.109.106195

    authors: Kopp M,Hermisson J

    更新日期:2009-12-01 00:00:00

  • Linkage disequilibrium in related breeding lines of chickens.

    abstract::High-density genotyping of single-nucleotide polymorphisms (SNPs) enables detection of quantitative trait loci (QTL) by linkage disequilibrium (LD) mapping using LD between markers and QTL and the subsequent use of this information for marker-assisted selection (MAS). The success of LD mapping and MAS depends on the e...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.082206

    authors: Andreescu C,Avendano S,Brown SR,Hassen A,Lamont SJ,Dekkers JC

    更新日期:2007-12-01 00:00:00

  • A sex chromosomal restriction-fragment-length marker linked to melanoma-determining Tu loci in Xiphophorus.

    abstract::In Xiphophorus, the causative genetic information for melanoma formation has been assigned by classical genetics to chromosomal loci, which are located on the sex chromosomes. In our attempts to molecularly clone these melanoma-determining loci, named Tu, we have looked for restriction-fragment-length markers (RFLMs) ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Schartl M

    更新日期:1988-07-01 00:00:00

  • Clines with asymmetric migration.

    abstract::The consequences of asymmetric dispersion on the maintenance of an allele in a one-dimensional environmental pocket are examined. The diffusion model of migration and selection is restricted to a single diallelic locus in a monoecious population in the absence of mutation and random drift. It is further supposed that ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Nagylaki T

    更新日期:1978-04-01 00:00:00