Distributional dynamics of a vulnerable species in response to past and future climate change: a window for conservation prospects.

abstract：Background:Endometriosis (EMs) is a non-malignant gynecological disease, whose pathogenesis remains to be clarified. Recent studies have found that hypoxia induces epithelial-mesenchymal transition (EMT) as well as epigenetic modification in EMs. However, the relationship between EMT and demethylation modification unde...

journal_title：PeerJ

authors： Wu J,Li X,Huang H,Xia X,Zhang M,Fang X

更新日期：2020-09-15 00:00:00

abstract：Background:Previous studies have shown that the mammalian thalamus is a key structure for anesthesia-induced unconsciousness and anesthesia-awakening regulation. However, both the dynamic characteristics and probable lateralization of thalamic functioning during anesthesia-awakening regulation are not fully understood,...

journal_title：PeerJ

authors： Fan Y,Yue X,Xue F,Brauth SE,Tang Y,Fang G

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:The present study investigated differences in reading and spelling outcomes in Dutch and English as a second language (ESL) in adolescents with a high familial risk of dyslexia, of whom some have developed dyslexia (HRDys) while others have not (HRnonDys), in comparison to a low familial risk control group w...

journal_title：PeerJ

authors： van Setten ERH,Tops W,Hakvoort BE,van der Leij A,Maurits NM,Maassen BAM

更新日期：2017-10-16 00:00:00

abstract：Background:Inhibition processing is sensitive to aging, and an age-related decline in inhibition processing has been associated with an accelerated rate of progression to Alzheimer disease. Elderly women are two to three times more likely than age-matched men to have Alzheimer disease. Therefore, this study examined wh...

journal_title：PeerJ

authors： Xu C,Lu Y,Wang B,Zhou C

更新日期：2019-03-18 00:00:00

abstract：:Previous studies of population genetic structure in Dissostichus eleginoides have shown that oceanographic and geographic discontinuities drive in this species population differentiation. Studies have focused on the genetics of D. eleginoides in the Southern Ocean; however, there is little knowledge of their genetic v...

journal_title：PeerJ

authors： Canales-Aguirre CB,Ferrada-Fuentes S,Galleguillos R,Oyarzun FX,Hernández CE

更新日期：2018-01-16 00:00:00

abstract：:There is growing concern that some bee populations are in decline, potentially threatening pollination security in agricultural and non-agricultural landscapes. Among the numerous causes associated with this trend, nutritional stress resulting from a mismatch between bee nutritional needs and plant community provision...

journal_title：PeerJ

authors： Pamminger T,Becker R,Himmelreich S,Schneider CW,Bergtold M

更新日期：2019-02-27 00:00:00

abstract：BACKGROUND:Individuals with mental illness often experience stigmatization and encounter stereotypes such as being dangerous or unpredictable. To further improve measures against psychiatric stigma, it is of importance to understand its components. In this study, we attend to the step of separation between "us" and "th...

journal_title：PeerJ

authors： Makowski AC,Mnich EE,Angermeyer MC,von dem Knesebeck O

更新日期：2016-09-27 00:00:00

abstract：:The p53 activation is induced by stressors, such as DNA damage, oxidative stress, and activated oncogenes, and can promote cell cycle arrest, cellular senescence, and apoptosis. The large yellow croaker (Larimichthys crocea) is an important warm temperate marine fish in the Chinese aquiculture industry. However, few s...

journal_title：PeerJ

authors： Qian B,Qi X,Bai Y,Wu Y

更新日期：2020-12-18 00:00:00

abstract：:Maternal thyroid hormones (THs) are known to be crucial in embryonic development in humans, but their influence on other, especially wild, animals remains poorly understood. So far, the studies that experimentally investigated the consequences of maternal THs focused on short-term effects, while early organisational e...

journal_title：PeerJ

authors： Sarraude T,Hsu BY,Groothuis T,Ruuskanen S

更新日期：2020-10-16 00:00:00

abstract：:LIMKi 3 is a specific selective LIMK inhibitor against LIMK1 and LIMK2, while LIMK1 and LIMK2 are the main regulators of actin cytoskeleton to participate in many cell activities. However, the effect of LIMKi 3 in porcine oocyte meiosis is still unclear. The present study was designed to investigate the effects of LIM...

journal_title：PeerJ

authors： Jia RX,Duan X,Song SJ,Sun SC

更新日期：2016-10-12 00:00:00

abstract：Background:Sex ratio distorting agents (maternally inherited symbionts and meiotically-driving sex chromosomes) are common in insects. When these agents rise to high frequencies they create strong population sex ratio bias and selection then favours mutations that act to restore the rare sex. Despite this strong select...

journal_title：PeerJ

authors： Reynolds LA,Hornett EA,Jiggins CD,Hurst GDD

更新日期：2019-10-01 00:00:00

abstract：:Alzheimer's disease is a multifactorial disorder caused by the interaction of genetic, epigenetic and environmental factors. The formation of cytotoxic oligomers consisting of Aβ peptide is widely accepted as being one of the main key events triggering the development of Alzheimer's disease. Aβ peptide production resu...

journal_title：PeerJ

authors： Parenti N,Del Grosso A,Antoni C,Cecchini M,Corradetti R,Pavone FS,Calamai M

更新日期：2017-04-12 00:00:00

abstract：:Barona arcuata, n.gen et n.sp., a left forewing of a relatively large cockroach of the Order Blattaria, is described from mesosaur-bearing lagoonal shales of the Mangrullo Formation (north-eastern Uruguay). While most of the insect remains recovered from the Mangrullo Formation come from sandy limestones, associated t...

journal_title：PeerJ

authors： Calisto V,Piñeiro G

更新日期：2019-01-18 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involved in HCC through multidimensional methods and revealed potential mole...

journal_title：PeerJ

authors： Liu ZK,Zhang RY,Yong YL,Zhang ZY,Li C,Chen ZN,Bian H

更新日期：2019-08-08 00:00:00

abstract：:Analysis of calcium sparks in cardiomyocytes can provide valuable information about functional changes of calcium handling in health and disease. As a part of the calcium sparks analysis, sparks detection and characterization is necessary. Here, we describe a new open-source platform for automatic calcium sparks detec...

journal_title：PeerJ

authors： Laasmaa M,Karro N,Birkedal R,Vendelin M

更新日期：2019-03-29 00:00:00

abstract：:Body condition is an important determinant of health, and its evaluation has practical applications for the conservation and management of mammals. We developed a noninvasive method that uses photographs to assess the body condition of free-ranging brown bears (Ursus arctos) in the Shiretoko Peninsula, Hokkaido, Japan...

journal_title：PeerJ

authors： Shirane Y,Mori F,Yamanaka M,Nakanishi M,Ishinazaka T,Mano T,Jimbo M,Sashika M,Tsubota T,Shimozuru M

更新日期：2020-09-18 00:00:00

abstract：Background:Geographic variation in body size and condition can reveal differential local adaptation to resource availability or climatic factors. Body size and condition are related to fitness in garter snakes (Thamnophis), thus good body condition may increase survival, fecundity in females, and mating success in male...

journal_title：PeerJ

authors： Valencia-Flores E,Venegas-Barrera CS,Fajardo V,Manjarrez J

更新日期：2019-03-13 00:00:00

abstract：:Autophagy serves as a turnover mechanism for the recycling of redundant and/or damaged macromolecules present in eukaryotic cells to re-use them under starvation conditions via a double-membrane structure known as autophagosome. A set of eukaryotic genes called autophagy-related genes (ATGs) orchestrate this highly el...

journal_title：PeerJ

authors： Aslan E,Küçükoğlu N,Arslanyolu M

更新日期：2017-01-17 00:00:00

abstract：Background:Evidences indicated that non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC) might originate from the same cell type, which however ended up to be two different subtypes of lung carcinoma, requiring different therapeutic regimens. We aimed to identify the differences between these two subtyp...

journal_title：PeerJ

authors： Wu J,Hao Z,Ma C,Li P,Dang L,Sun S

更新日期：2020-04-23 00:00:00

abstract：:Cedecea neteri is a very rare human pathogen. We have isolated a strain of C. neteri SSMD04 from pickled mackerel sashimi identified using molecular and phenotypics approaches. Using the biosensor Chromobacterium violaceum CV026, we have demonstrated the presence of short chain N-acyl-homoserine lactone (AHL) type quo...

journal_title：PeerJ

authors： Tan KH,Tan JY,Yin WF,Chan KG

更新日期：2015-09-01 00:00:00

abstract：:The evolution of the modern human (Homo sapiens) cranium is characterized by a reduction in the size of the feeding system, including reductions in the size of the facial skeleton, postcanine teeth, and the muscles involved in biting and chewing. The conventional view hypothesizes that gracilization of the human feedi...

journal_title：PeerJ

authors： Ledogar JA,Dechow PC,Wang Q,Gharpure PH,Gordon AD,Baab KL,Smith AL,Weber GW,Grosse IR,Ross CF,Richmond BG,Wright BW,Byron C,Wroe S,Strait DS

更新日期：2016-07-26 00:00:00

abstract：Background:Understanding individual food preferences is critical for creating tailored strategies that promote healthy individual eating behaviors. Individual sensory liking appears to be an essential determinant of dietary intake. Taste preferences influence satisfaction and satiety, and may consequently influence wei...

journal_title：PeerJ

authors： Petre LM,Vatasescu BN

更新日期：2019-12-06 00:00:00

abstract：:Because microorganisms are sensitive to temperature, ongoing global warming is predicted to influence microbial community structure and function. We used large-scale warming experiments established at two sites near the northern and southern boundaries of US eastern deciduous forests to explore how microbial communiti...

journal_title：PeerJ

authors： Cregger MA,Sanders NJ,Dunn RR,Classen AT

更新日期：2014-04-24 00:00:00

abstract：:Esophageal cancer is a common malignant tumor in the world, and the aim of this study was to screen key genes related to the development of esophageal cancer using a variety of bioinformatics analysis tools and analyze their biological functions. The data of esophageal squamous cell carcinoma from the Gene Expression ...

journal_title：PeerJ

authors： Guan X,Yao Y,Bao G,Wang Y,Zhang A,Zhong X

更新日期：2020-03-31 00:00:00

abstract：:The post-genomic era is characterized by the direct acquisition and analysis of genomic data with many applications, including the enhancement of the understanding of microbial epidemiology and pathology. However, there are a number of molecular approaches to survey pathogen diversity, and the impact of these differen...

journal_title：PeerJ

authors： Castro-Nallar E,Hasan NA,Cebula TA,Colwell RR,Robison RA,Johnson WE,Crandall KA

更新日期：2015-02-17 00:00:00

abstract：:Computerised cognitive assessments are a vital tool in the behavioural sciences, but participants often view them as effortful and unengaging. One potential solution is to add gamelike elements to these tasks in order to make them more intrinsically enjoyable, and some researchers have posited that a more engaging tas...

journal_title：PeerJ

authors： Lumsden J,Skinner A,Woods AT,Lawrence NS,Munafò M

更新日期：2016-07-06 00:00:00

abstract：BACKGROUND:Motion sickness may be caused by a sensory conflict between the visual and the vestibular systems. Scopolamine, known to be the most effective therapy to control the vegetative symptoms of motion sickness, acts on the vestibular nucleus and potentially the vestibulospinal pathway, which may affect balance an...

journal_title：PeerJ

authors： Bestaven E,Kambrun C,Guehl D,Cazalets JR,Guillaud E

更新日期：2016-05-05 00:00:00

abstract：BACKGROUND:The composition of the salivary microbiota has been reported to differentiate between patients with periodontitis, dental caries and orally healthy individuals. To identify characteristics of diseased and healthy saliva we thus wanted to compare saliva metaproteomes from patients with periodontitis and denta...

journal_title：PeerJ

authors： Belstrøm D,Jersie-Christensen RR,Lyon D,Damgaard C,Jensen LJ,Holmstrup P,Olsen JV

更新日期：2016-09-14 00:00:00

abstract：Background:During a preliminary study, effects of 0, 20, 40, and 60 mM NaCl salinity were assessed on germination rate in relation to electrolyte leakage (EL) in sweet pepper. Results explored significant rises in ethylene evolution from seeds having more EL. It was, therefore, hypothesized that excessive ethylene bios...

journal_title：PeerJ

authors： Ahmed W,Imran M,Yaseen M,Haq TU,Jamshaid MU,Rukh S,Ikram RM,Ali M,Ali A,Maqbool M,Arif M,Khan MA

更新日期：2020-03-27 00:00:00

abstract：:In recent years, the use of lectins for screening of potential biomarkers has gained increased importance in cancer research, given the development in glycobiology that highlights altered structural changes of glycans in cancer associated processes. Lectins, having the properties of recognizing specific carbohydrate m...

journal_title：PeerJ

authors： Hashim OH,Jayapalan JJ,Lee CS

更新日期：2017-09-07 00:00:00