IOCBIO Sparks detection and analysis software.

abstract：Background:Mimusops coriacea (A.DC.) Miq., (Sapotaceae), originated from Africa, were introduced to coastal areas in Ecuador where it is not extensively used as a traditional medicine to treat various human diseases. Different therapeutically uses of the species include: analgesic, antimicrobial, hypoglycemic, inflamma...

journal_title：PeerJ

authors： Bustamante K,Santos-Ordóñez E,Miranda M,Pacheco R,Gutiérrez Y,Scull R

更新日期：2019-10-11 00:00:00

abstract：Background:Inflammatory bowel diseases are associated with remodeling of neuronal circuitries within the enteric nervous system, occurring also at sites distant from the acute site of inflammation and underlying disturbed intestinal functions. Homeoproteins orthodenticle OTX1 and OTX2 are neuronal transcription factors...

journal_title：PeerJ

authors： Bistoletti M,Micheloni G,Baranzini N,Bosi A,Conti A,Filpa V,Pirrone C,Millefanti G,Moro E,Grimaldi A,Valli R,Baj A,Crema F,Giaroni C,Porta G

更新日期：2020-02-13 00:00:00

abstract：:Ethylene response factors (ERFs) are plant-specific transcription factors (TFs) that play important roles in plant growth and stress defense and have received a great amount of attention in recent years. In this study, seven ERF genes related to abiotic stress tolerance and response were identified in plants of the Po...

journal_title：PeerJ

authors： Huang J,Wang S,Wang X,Fan Y,Han Y

更新日期：2020-10-20 00:00:00

abstract：:Sugarcane Bacilliform Guadeloupe A Virus (SCBGAV, genus Badnavirus, family Caulimoviridae) is an emerging, deleterious pathogen of sugarcane which presents a substantial barrier to producing high sugarcane earnings. Sugarcane bacilliform viruses (SCBVs) are one of the main species that infect sugarcane. During the las...

journal_title：PeerJ

authors： Ashraf F,Ashraf MA,Hu X,Zhang S

更新日期：2020-01-13 00:00:00

abstract：:Background. Most genetic disorders are caused by single nucleotide variations (SNVs) or small insertion/deletions (indels). High throughput sequencing has broadened the catalogue of human variation, including common polymorphisms, rare variations or disease causing mutations. However, identifying one variation among h...

journal_title：PeerJ

authors： Geoffroy V,Pizot C,Redin C,Piton A,Vasli N,Stoetzel C,Blavier A,Laporte J,Muller J

更新日期：2015-03-03 00:00:00

abstract：:Sex reversal is a complex biological phenomenon exhibited by Cynoglossus semilaevis. Some genetic females may irreversibly convert to pseudomales, thus increasing aquaculture costs because males grow much more slowly than females. In this study, an integrative analysis of transcriptome and proteome was performed to co...

journal_title：PeerJ

authors： Ye Z,Wang W,Zhang Y,Wang L,Cui Y,Li H

更新日期：2020-03-19 00:00:00

abstract：:MicoRNAs (miRNAs), usually as gene regulators, participate in various biological processes, including stress responses. The hypothalamus-pituitary-adrenal axis (HPA axis) is an important pathway in regulating stress response. Although the mechanism that HPA axis regulates stress response has been basically revealed, t...

journal_title：PeerJ

authors： Luo W,Fang M,Xu H,Xing H,Fu J,Nie Q

更新日期：2016-02-18 00:00:00

abstract：Background:Circadian genes have been suggested to play an important role in lung pathology. However, it remains unknown whether polymorphisms of these genes are associated with chronic obstructive pulmonary disease (COPD). Here, we aimed to investigate the association of circadian genes polymorphisms with COPD in a cas...

journal_title：PeerJ

authors： Chen G,Zhang J,Zhang L,Xiong X,Yu D,Zhang Y

更新日期：2020-08-27 00:00:00

abstract：:The rapidly changing climate makes humans realize that there is a critical need to incorporate climate change adaptation into conservation planning. Whether the wintering habitats of Great Bustards (Otis tarda dybowskii), a globally endangered migratory subspecies whose population is approximately 1,500-2,200 individu...

journal_title：PeerJ

authors： Mi C,Falk H,Guo Y

更新日期：2016-02-01 00:00:00

abstract：:A greenhouse experiment was carried out to investigate the effects of arbuscular mycorrhizal fungi (AMF) on the growth, P and Cd concentrations and bioenergy quality-related factors of five cultivars of switchgrass, including three lowland cultivars (Alamo (Ala), Kanlow (Kan), Performer (Per)) and two highland cultiva...

journal_title：PeerJ

authors： Sun H,Xie Y,Zheng Y,Lin Y,Yang F

更新日期：2018-03-06 00:00:00

abstract：Background:Skeletal muscle wound healing is dependent on complex interactions between fibroblasts, myofibroblasts, myogenic cells, and cytokines, such as TGF-β1. This study sought to clarify the impact of TGF-β1 signaling on skeletal muscle cells and discern between the individual contributions of fibroblasts and myofi...

journal_title：PeerJ

authors： Krieger J,Park BW,Lambert CR,Malcuit C

更新日期：2018-07-11 00:00:00

abstract：:Atoposaurid crocodyliforms represent an important faunal component of Late Jurassic to Early Cretaceous Laurasian semi-aquatic to terrestrial ecosystems, with numerous spatiotemporally contemporaneous atoposaurids known from western Europe. In particular, the Late Jurassic of France and Germany records evidence for hi...

journal_title：PeerJ

authors： Tennant JP,Mannion PD

更新日期：2014-09-25 00:00:00

abstract：:In summer 2012, we initiated a large-scale field experiment in southern Ontario, Canada, to determine whether exposure to clothianidin seed-treated canola (oil seed rape) has any adverse impacts on honey bees. Colonies were placed in clothianidin seed-treated or control canola fields during bloom, and thereafter were ...

journal_title：PeerJ

authors： Cutler GC,Scott-Dupree CD,Sultan M,McFarlane AD,Brewer L

更新日期：2014-10-30 00:00:00

abstract：:Herein, we identified the tomato SlMYB102 gene as a MYB family transcription factor of the R2R3-MYB subfamily. We additionally determined that the SlMYB102 promoter region contains photoresponsive, abiotic stress-responsive, and hormone-responsive regulatory elements, and we detected higher SlMYB102 expression in the ...

journal_title：PeerJ

authors： Wang M,Hao J,Chen X,Zhang X

更新日期：2020-10-07 00:00:00

abstract：Background:Administration of anandamide (AEA) or 2-arachidonoylglycerol (2AG) induces CB1 coupling and activation of TRKB receptors, regulating the neuronal migration and maturation in the developing cortex. However, at higher concentrations AEA also engages vanilloid receptor TRPV1, usually with opposed consequences o...

journal_title：PeerJ

authors： Diniz CRAF,Biojone C,Joca SRL,Rantamäki T,Castrén E,Guimarães FS,Casarotto PC

更新日期：2019-02-21 00:00:00

abstract：Background:Humpback whales (Megaptera novaeangliae) are a widespread, vocal baleen whale best known for producing song, a complex, repetitive, geographically distinct acoustic signal sung by males, predominantly in a breeding context. Humpback whales worldwide also produce non-song vocalizations ("calls") throughout th...

journal_title：PeerJ

authors： Fournet MEH,Jacobsen L,Gabriele CM,Mellinger DK,Klinck H

更新日期：2018-07-30 00:00:00

abstract：Background:We investigated the effects of gastric Helicobacter pylori infection on the daytime and overnight human oral microbiota. Methods:Twenty four volunteers were recruited. Ten tested positive for H. pylori infection by the Carbon-14 Urea Breath Test, and the rest were negative. Two oral swabs were collected: on...

journal_title：PeerJ

authors： Chua EG,Chong JY,Lamichhane B,Webberley KM,Marshall BJ,Wise MJ,Tay CY

更新日期：2019-01-28 00:00:00

abstract：:The ability to accurately identify and label emotions in the self and others is crucial for successful social interactions and good mental health. In the current study we tested the longitudinal relationship between early language skills and recognition of facial and vocal emotion cues in a representative UK populatio...

journal_title：PeerJ

authors： Griffiths S,Goh SKY,Norbury CF,the SCALES team.

更新日期：2020-05-12 00:00:00

abstract：:A strong argument can be made that the European Union has the most rigorous regulatory system for pesticides in the world, and that modern pesticide use poses fewer environmental threats than older regimes. Nevertheless, the impacts of pesticides on bees and other non-target organisms are much debated in Europe as els...

journal_title：PeerJ

authors： Goulson D,Thompson J,Croombs A

更新日期：2018-07-19 00:00:00

abstract：Background:Leucojum aestivum L. is an important medicinal plant which produces Amaryllidaceae alkaloids, especially galanthamine and lycorine. Research is currently exploring the possibility of producing these alkaloids using biotechnological methods, including in vitro cultures. The biosynthesis of alkaloids may be af...

journal_title：PeerJ

authors： Ptak A,Morańska E,Skrzypek E,Warchoł M,Spina R,Laurain-Mattar D,Simlat M

更新日期：2020-03-16 00:00:00

abstract：Background:The functional significance of ADAMs family members in the immune infiltration of pancreatic adenocarcinoma (PAAD) awaits elucidation. Methods:ADAMs family members with significant expression were identified among differentially expressed genes of PAAD based on The Cancer Genome Atlas (TCGA) database follow...

journal_title：PeerJ

authors： Qi B,Liu H,Dong Y,Shi X,Zhou Q,Zeng F,Bao N,Li Q,Yuan Y,Yao L,Xia S

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:As one of the highest forest ecosystems in the world, Polylepis forests are recognized both as center of endemism and diversity along the Andes and as an ecosystem under serious threat from habitat loss, fragmentation, and climate change due to human activities. Effective conservation efforts are limited, in...

journal_title：PeerJ

authors： Sevillano-Ríos CS,Rodewald AD

更新日期：2017-04-27 00:00:00

abstract：:Porcine epidemic diarrhea virus (PEDV) outbreaks on pig farms have caused significant economic loss in the swine industry since it was first reported in Thailand a decade ago. Anecdotal evidence suggests that PEDV is now endemic in this region, therefore genome information of circulating PEDV is important for molecula...

journal_title：PeerJ

authors： Tuanthap S,Vongpunsawad S,Phupolphan C,Duang-In A,Wattanaphansak S,Assavacheep P,Theamboonlers A,Luengyosluechakul S,Amonsin A,Poovorawan Y

更新日期：2019-04-30 00:00:00

abstract：:The interconversion of hexose-6-phosphate and hexose-1-phosphate can be directly analyzed by high-performance anion-exchange chromatography coupled with an electrochemical detector (HPAEC-PAD). Thus, this method can be used to measure the activities of N-acetylglucosamine-phosphate mutase (AGM), glucosamine-phosphate ...

journal_title：PeerJ

authors： Jia X,Kang J,Yin H

更新日期：2016-01-05 00:00:00

abstract：Aims:Periodontitis and psoriatic disease, including psoriasis (PS) and psoriatic arthritis (PsA), share the common risk factors and co-morbidities. However, the risk of periodontitis in patients with psoriatic disease still needs further investigation. This study was a nationwide population-based retrospective cohort s...

journal_title：PeerJ

authors： Su NY,Huang JY,Hu CJ,Yu HC,Chang YC

更新日期：2017-11-16 00:00:00

abstract：:Alcohol drinking may be associated with an increased risk of various metabolic diseases. Rat lines selectively bred for alcohol preference and alcohol avoidance constitute an interesting model to study inherited factors related to alcohol drinking and metabolic disorders. The aim of the present study was to compare th...

journal_title：PeerJ

authors： Mierzejewski P,Zakrzewska A,Kuczyńska J,Wyszogrodzka E,Dominiak M

更新日期：2020-09-11 00:00:00

abstract：Background:Previous studies have indicated that physical exercise enhances attentional function; however, the relationship between exercise mode and attentional networks has not been clarified for older adults (>60 years old). This study aimed to investigate the relationship between attentional networks and different e...

journal_title：PeerJ

authors： Wang B,Guo W

更新日期：2020-01-07 00:00:00

abstract：:This paper investigates the capabilities of the evolutionary fuzzy genetic (FG) approach and compares it with three neuro-fuzzy methods-neuro-fuzzy with grid partitioning (ANFIS-GP), neuro-fuzzy with subtractive clustering (ANFIS-SC), and neuro-fuzzy with fuzzy c-means clustering (ANFIS-FCM)-in terms of modeling long-...

journal_title：PeerJ

authors： Sadeghi-Niaraki A,Kisi O,Choi SM

更新日期：2020-08-14 00:00:00

abstract：:The enhanced ability to direct sexual reproduction may lead to improved restoration outcomes for Acropora cervicornis. Gravid fragments of A. cervicornis were maintained in a laboratory for two sequential trials in the seven days prior to natural spawning in the Florida Keys. Ten replicates of five chemicals known to ...

journal_title：PeerJ

authors： Flint M,Than JT

更新日期：2016-04-26 00:00:00

abstract：:Fungi play a critical role in a range of ecosystems; however, their interactions and functions in marine hosts, and particular sponges, is poorly understood. Here we assess the fungal community composition of three co-occurring sponges (Cymbastela concentrica, Scopalina sp., Tedania anhelans) and the surrounding seawa...

journal_title：PeerJ

authors： Nguyen MTHD,Thomas T

更新日期：2018-06-04 00:00:00