Testing the short-and long-term effects of elevated prenatal exposure to different forms of thyroid hormones.

abstract：Background:Cyclin A overexpression is found in a variety of human tumors and correlates with unfavorable outcome. We analyzed immunohistochemical expression of cyclin A in Wilms tumor (WT) in relation to clinicopathological characteristics, preoperative chemotherapy (PrOpChTh), and overall survival (OS). Methods:This ...

journal_title：PeerJ

authors： Radojević-Škodrić S,Brašanac D,Đuričić SM,Glumac S,Lončar Z,Pavlović I,Todorović A,Nikolić G,Baralić I,Pejić S

更新日期：2019-01-11 00:00:00

abstract：:Garden Warblers Sylvia borin were studied during autumn stopover in Crete before crossing the barrier of the Mediterranean Sea and the Sahara Desert. Birds followed with transmitters show extensive stopover periods, which were longer in first-year birds, 16 days, compared with adult birds, 14 days. The distribution of...

journal_title：PeerJ

authors： Barboutis C,Henshaw I,Kullberg C,Nikolopoulou S,Fransson T

更新日期：2014-03-25 00:00:00

abstract：:Osteogenic cells form mineralized matrices in vitro, as well as in vivo. The formation and shape of the mineralized matrices are highly regulated by the cells. In vitro formation of mineralized matrices by osteogenic cells can be a model for in vivo osteogenesis. In this study, using a three-dimensional (3D) collagen ...

journal_title：PeerJ

authors： Kihara T,Umezu C,Sawada K,Furutani Y

更新日期：2019-10-23 00:00:00

abstract：:Background. Most genetic disorders are caused by single nucleotide variations (SNVs) or small insertion/deletions (indels). High throughput sequencing has broadened the catalogue of human variation, including common polymorphisms, rare variations or disease causing mutations. However, identifying one variation among h...

journal_title：PeerJ

authors： Geoffroy V,Pizot C,Redin C,Piton A,Vasli N,Stoetzel C,Blavier A,Laporte J,Muller J

更新日期：2015-03-03 00:00:00

abstract：Background:The increasing production of sewage sludge (SS) engenders the problem of its responsible utilization and disposal. Likewise, urban sediments (SED) are deposited at the bottom of urban reservoirs and sedimentation ponds, and these require periodical dredging and utilization. However, while the SS and SED depo...

journal_title：PeerJ

authors： Wyrwicka A,Urbaniak M,Przybylski M

更新日期：2019-05-01 00:00:00

abstract：Background:Herpesviral hematopoietic necrosis disease, caused by cyprinid herpesvirus-2 (CyHV-2), is responsible for massive mortalities in the aquaculture of goldfish, Carassius auratus. Permissive cell lines for the isolation and propagation of CyHV-2 have been established from various goldfish tissues by sacrificing...

journal_title：PeerJ

authors： Dharmaratnam A,Kumar R,Valaparambil BS,Sood N,Pradhan PK,Das S,Swaminathan TR

更新日期：2020-07-14 00:00:00

abstract：:We examined whether chemically mediated risk perception by prey and the effects of changes in prey behavior on basal resources vary as a function of the amount of prey biomass consumed by the predator. We studied these issues using a tritrophic system composed of blue crabs, Callinectes sapidus (top predator), mud cra...

journal_title：PeerJ

authors： Weissburg M,Beauvais J

更新日期：2015-11-19 00:00:00

abstract：Objective:To explore the blood pressure response to different ablation points of renal denervation (RDN) in patients with resistant hypertension. Methods:A total of 42 cases with resistant hypertension treated by RDN in our center from 2013 to 2015 were retrospectively analyzed. The patients were divided into two grou...

journal_title：PeerJ

authors： Zhang H,Li LY,Xiao RX,Zhang TC,Liu ZJ,Gao JQ

更新日期：2020-09-15 00:00:00

abstract：:Pueraria lobata (willd.) Ohwi is a consumable selenium-enriched plant used for medicinal purposes. The molecular response to selenium (Se) stimuli in P. lobata is currently unknown. We used RNA-Seq to identify potential genes involved in selenite metabolism and analyzed their expression profiles. We obtained a total o...

journal_title：PeerJ

authors： Guo K,Yao Y,Yang M,Li Y,Wu B,Lin X

更新日期：2020-03-24 00:00:00

abstract：:The most intense commercial harvest of marine aquarium species in North America occurs in the coastal waters surrounding Florida, yet very often little information exists on the life histories, population dynamics, or reproductive characteristics of these organisms. The peppermint shrimp Lysmata boggessi is one such s...

journal_title：PeerJ

authors： Dickson MD,Behringer DC,Baeza JA

更新日期：2020-01-23 00:00:00

abstract：Purpose:Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods:A retrospective, single-center case series study of 275 NBs was implem...

journal_title：PeerJ

authors： Ma Y,Zheng J,Feng J,Chen L,Dong K,Xiao X

更新日期：2018-09-17 00:00:00

abstract：Background:A virus-like particle (VLP) is an excellent tool for a compound delivery system due to its simple composition, symmetrical structure and self-assembly. Its surface modification both chemically and genetically is established, leading to the target-specific delivery and improved encapsulation efficiency. Howev...

journal_title：PeerJ

authors： Kiatmetha P,Chotwiwatthanakun C,Jariyapong P,Santimanawong W,Ounjai P,Weerachatyanukul W

更新日期：2018-12-18 00:00:00

abstract：:Autophagy serves as a turnover mechanism for the recycling of redundant and/or damaged macromolecules present in eukaryotic cells to re-use them under starvation conditions via a double-membrane structure known as autophagosome. A set of eukaryotic genes called autophagy-related genes (ATGs) orchestrate this highly el...

journal_title：PeerJ

authors： Aslan E,Küçükoğlu N,Arslanyolu M

更新日期：2017-01-17 00:00:00

abstract：:The Asian clam, Corbicula fluminea, is a commonly consumed small freshwater bivalve in East Asia. However, available genetic information of this clam is still limited. In this study, the transcriptome of female C. fluminea was sequenced using the Illumina HiSeq 2500 platform. A total of 89,563 unigenes were assembled ...

journal_title：PeerJ

authors： Zhu C,Zhang L,Ding H,Pan Z

更新日期：2019-10-22 00:00:00

abstract：Background:Vitamin D 1α-hydroxylase CYP27B1 is the key factor in the vitamin D pathway. Previously, we analyzed the expression of CYP27B1 in human gingival fibroblasts in vitro. In the present study, we analyzed the gingival expression of CYP27B1 in vivo. Methods:Forty-two patients with periodontitis Stage IV Grade C ...

journal_title：PeerJ

authors： Liu K,Han B,Hou J,Zhang J,Su J,Meng H

更新日期：2021-01-04 00:00:00

abstract：Background:Acute respiratory distress syndrome (ARDS) is associated with significantly increased risk of death, and early risk stratification may help to choose the appropriate treatment. The study aimed to develop a neural network model by using a genetic algorithm (GA) for the prediction of mortality in patients with...

journal_title：PeerJ

authors： Zhang Z

更新日期：2019-09-16 00:00:00

abstract：:It has been reported that fermented products (FPs) prepared from sweet potato-shochu distillery by-product suppressed weight gain and decreased serum cholesterol levels in mice under normal dietary conditions. Furthermore, from the information gained from the above data regarding health benefits of the FPs, the aim of...

journal_title：PeerJ

authors： Kosakai T,Kato H,Sho C,Kawano K,Iwai KI,Takase Y,Ogawa K,Nishiyama K,Yamasaki M

更新日期：2019-09-12 00:00:00

abstract：:Purple Broccoli (Brassica oleracea L. var italica) attracts growing attention as a functional food. Its purple coloration is due to high anthocyanin amounts. Light represents a critical parameter affecting anthocyanins biosynthesis. In this study, 'Purple Broccoli', a light-responding pigmentation cultivar, was assess...

journal_title：PeerJ

authors： Liu C,Yao X,Li G,Huang L,Xie Z

更新日期：2020-05-05 00:00:00

abstract：:[This corrects the article DOI: 10.7717/peerj.4110.]. ...

journal_title：PeerJ

authors： van Heteren AH,van Dierendonck RCH,van Egmond MANE,Ten Hagen SL,Kreuning J

更新日期：2017-12-20 00:00:00

abstract：:The monoamines serotonin and dopamine are important neuromodulators present in the central nervous system, known to be active regulators of social behaviour in fish as in other vertebrates. Our aim was to investigate the region-specific brain monoaminergic differences arising when individual cleaners face a client (mu...

journal_title：PeerJ

authors： de Abreu MS,Messias JPM,Thörnqvist PO,Winberg S,Soares MC

更新日期：2018-05-24 00:00:00

abstract：:Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small si...

journal_title：PeerJ

authors： Maslo B,Schlacher TA,Weston MA,Huijbers CM,Anderson C,Gilby BL,Olds AD,Connolly RM,Schoeman DS

更新日期：2016-09-13 00:00:00

abstract：:Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensu...

journal_title：PeerJ

authors： Kippner LE,Kim J,Gibson G,Kemp ML

更新日期：2014-06-24 00:00:00

abstract：:As conspicuous modular components of benthic marine habitats, gorgonian (sea fan) octocorals have perplexed taxonomists for centuries through their shear diversity, particularly throughout the Indo-Pacific. Phenotypic incongruence within and between seemingly unitary lineages across contrasting environments can provid...

journal_title：PeerJ

authors： Rowley SJ,Pochon X,Watling L

更新日期：2015-08-20 00:00:00

abstract：Background:Conserving both biodiversity and ecosystem services is a major goal of the Convention on Biological Diversity. Hotspots for biodiversity in the Andes significantly overlap with areas with dense human populations that sustain their economy through agricultural production. Therefore, developing management form...

journal_title：PeerJ

authors： Quintana C,Girardello M,Balslev H

更新日期：2019-02-13 00:00:00

abstract：:Natural and anthropogenic changes (e.g., land use change, pollution) will alter many environmental factors in the coming years, including the amount of solar radiation reaching the earth's surface. Alterations in solar radiation exposure is likely to impact the ecologies of many living organisms, including invertebrat...

journal_title：PeerJ

authors： Villena OC,Momen B,Sullivan J,Leisnham PT

更新日期：2018-12-18 00:00:00

abstract：Background:Alcohol-related hepatocellular carcinoma (HCC) was reported to be diagnosed at a later stage, but the mechanism was unknown. This study aimed to identify special key genes (SKGs) during alcohol-related HCC development and progression. Methods:The mRNA data of 369 HCC patients and the clinical information we...

journal_title：PeerJ

authors： Zhang X,Kang C,Li N,Liu X,Zhang J,Gao F,Dai L

更新日期：2019-02-06 00:00:00

abstract：:Objective. We hypothesized that a significant percentage of patients who are referred to the Emergency Department (ED) after calling their primary care physician's (PCP) office receive such instructions without the input of a physician. Methods. We enrolled a convenience sample of stable adults at an inner-city ED. Pa...

journal_title：PeerJ

authors： Hill R,Gest A,Smith C,Guardiola JH,Apolinario M,Ha J,Gonzalez JR,Richman PB

更新日期：2016-03-28 00:00:00

abstract：Background:The influenza virus can cause seasonal infections with mild to severe symptoms, circulating worldwide, and it can affect people in any age group. Therefore, this infection is a serious public health problem that causes severe illness and death in high-risk populations. Every year, 0.5% of the world's populat...

journal_title：PeerJ

authors： Silva T,S Salomon P,Hamerski L,Walter J,B Menezes R,Siqueira JE,Santos A,Santos JAM,Ferme N,Guimarães T,O Fistarol G,I Hargreaves P,Thompson C,Thompson F,Souza TM,Siqueira M,Miranda M

更新日期：2018-10-26 00:00:00

abstract：Background:Magnetite-mediated direct interspecies electron transfer (DIET) between Geobacter and Methanosarcina species is increasingly being invoked to explain magnetite stimulation of methane production in anaerobic soils and sediments. Although magnetite-mediated DIET has been documented in defined co-cultures reduc...

journal_title：PeerJ

authors： Wang O,Zheng S,Wang B,Wang W,Liu F

更新日期：2018-03-21 00:00:00

abstract：:Staurozoan classification is highly subjective, based on phylogeny-free inferences, and suborders, families, and genera are commonly defined by homoplasies. Additionally, many characters used in the taxonomy of the group have ontogenetic and intraspecific variation, and demand new and consistent assessments to establi...

journal_title：PeerJ

authors： Miranda LS,Hirano YM,Mills CE,Falconer A,Fenwick D,Marques AC,Collins AG

更新日期：2016-05-05 00:00:00