Immunohistochemical analysis of cyclin A expression in Wilms tumor.

abstract：Background:Hair follicles in cashmere goats are divided into primary and secondary hair follicles (HFs). HF development, which determines the morphological structure, is regulated by a large number of vital genes; however, the key functional genes and their interaction networks are still unclear. Although the vitamin D...

journal_title：PeerJ

authors： Gao Y,Jin M,Niu Y,Yan H,Zhou G,Chen Y

更新日期：2019-07-03 00:00:00

abstract：Background:Dengue infection represents a global health issue of growing importance. Dengue non-structural protein 1 (NS1) plays a central role in the early detection of the disease. The most common method for NS1 detection is testing by lateral flow immunoassays (LFIAs) with varying sensitivity. In this study, we prese...

journal_title：PeerJ

authors： Tran TV,Nguyen BV,Nguyen TTP,Tran TT,Pham KG,Le QB,Do BN,Pham HN,Nguyen CV,Dinh DPH,Ha VT,Doan THT,Le HQ

更新日期：2019-09-25 00:00:00

abstract：:Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensu...

journal_title：PeerJ

authors： Kippner LE,Kim J,Gibson G,Kemp ML

更新日期：2014-06-24 00:00:00

abstract：:The common bottlenose dolphin, Tursiops truncatus, is widely distributed along the western coast of South America. In Ecuador, a resident population of bottlenose dolphins inhabits the inner estuarine area of the Gulf of Guayaquil located in the southwestern part of the country and is under threat from different human...

journal_title：PeerJ

authors： Bayas-Rea RLÁ,Félix F,Montufar R

更新日期：2018-04-09 00:00:00

abstract：Background:B-mode ultrasound is one of the most commonly used imaging techniques for evaluating thyroid nodules due to its noninvasive property and excellent performance in terms of discriminating between benign and malignant nodules. However, the accuracy of differential diagnosis strongly depends on the experience of...

journal_title：PeerJ

authors： Wang J,He X,Ma L,Li M,Sun L,Jiang J,Zhou Q

更新日期：2020-05-04 00:00:00

abstract：:Aedes aegypti is the major vector of dengue, yellow fever and chikungunya viruses that put millions of people in endemic countries at risk. Mass rearing of this mosquito is crucial for strategies that use modified insects to reduce vector populations and transmission of pathogens, such as sterile insect technique or p...

journal_title：PeerJ

authors： Gonzales KK,Tsujimoto H,Hansen IA

更新日期：2015-05-05 00:00:00

abstract：:Metoposaurids are representatives of the extinct amphibian clade Temnospondyli, found on almost every continent exclusively in the Late Triassic deposits. Osteohistologically, it is one of the best-known temnospondyl groups, analyzed with a wide spectrum of methods, such as morphology, morphometry, bone histology or c...

journal_title：PeerJ

authors： Teschner EM,Chakravorti S,Sengupta DP,Konietzko-Meier D

更新日期：2020-09-08 00:00:00

abstract：BACKGROUND:Essential oil components (EOCs) are molecules with interesting application in pest control, these have been evaluated against different insect pest from more than 100 years, but their practical use is rather limited. Thus, the enhancement of their bioavailability and manageability due to their dispersion in ...

journal_title：PeerJ

authors： Lucia A,Toloza AC,Guzmán E,Ortega F,Rubio RG

更新日期：2017-04-20 00:00:00

abstract：:A new species of Scutalus Albers, 1850 (Gastropoda: Bulimulidae), Scutalus chango sp. n., is described from a coastal area of northern Chile. Empty shells of this new species were found buried in sand and under boulders and rocks in the foothills of the Chilean Coastal Range at Paposo, Región de Antofagasta. This new ...

journal_title：PeerJ

authors： Araya JF,Breure ASH

更新日期：2017-07-05 00:00:00

abstract：:Harmine is the β-carboline alkaloid with the highest concentration in the psychotropic plant decoction Ayahuasca. In rodents, classical antidepressants reverse the symptoms of depression by stimulating neuronal proliferation. It has been shown that Ayahuasca presents antidepressant effects in patients with depressive ...

journal_title：PeerJ

authors： Dakic V,Maciel RM,Drummond H,Nascimento JM,Trindade P,Rehen SK

更新日期：2016-12-06 00:00:00

abstract：Purpose:Pterygium results from a variety of biological pathways that are involved in the formation of ocular surface diseases. However, the exact pathogenesis of pterygium is still unclear. Our study focused on gene expression profiles to better understand the potential mechanisms of pterygium. Methods:RNA sequencing ...

journal_title：PeerJ

authors： Chen Y,Wang H,Jiang Y,Zhang X,Wang Q

更新日期：2020-05-04 00:00:00

abstract：:Metabarcoding can rapidly determine the species composition of bulk samples and thus aids biodiversity and ecosystem assessment. However, it is essential to use primer sets that minimize amplification bias among taxa to maximize species recovery. Despite this fact, the performance of primer sets employed for metabarco...

journal_title：PeerJ

authors： Elbrecht V,Braukmann TWA,Ivanova NV,Prosser SWJ,Hajibabaei M,Wright M,Zakharov EV,Hebert PDN,Steinke D

更新日期：2019-10-07 00:00:00

abstract：Background:Recent studies have shown that people with high alexithymia scores have decreased interoceptive abilities, which can be associated with psychological and physical disorders. Early assessments of the alexithymia trait included the evaluation of these abilities through the dimension measuring the difficulty in...

journal_title：PeerJ

authors： Fournier A,Luminet O,Dambrun M,Dutheil F,Pellissier S,Mondillon L

更新日期：2019-11-20 00:00:00

abstract：:Dinocephalian therapsids are renowned for their massive, pachyostotic and ornamented skulls adapted for head-to-head fighting during intraspecific combat. Synchrotron scanning of the tapinocephalid Moschops capensis reveals, for the first time, numerous anatomical adaptations of the central nervous system related to t...

journal_title：PeerJ

authors： Benoit J,Manger PR,Norton L,Fernandez V,Rubidge BS

更新日期：2017-08-10 00:00:00

abstract：:Background. Quotations and references are an indispensable element of scientific communication. They should support what authors claim or provide important background information for readers. Studies indicate, however, that quotations not serving their purpose-quotation errors-may be prevalent. Methods. We carried out...

journal_title：PeerJ

authors： Jergas H,Baethge C

更新日期：2015-10-27 00:00:00

abstract：:This study aimed (i) to explore the relationship between vertical (jumping) and horizontal (sprinting) force-velocity-power (FVP) mechanical profiles in a large range of sports and levels of practice, and (ii) to provide a large database to serve as a reference of the FVP profile for all sports and levels tested. A to...

journal_title：PeerJ

authors： Jiménez-Reyes P,Samozino P,García-Ramos A,Cuadrado-Peñafiel V,Brughelli M,Morin JB

更新日期：2018-11-13 00:00:00

abstract：Context:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with unknown etiology. Objective:Human plasma is comprised of over 10 orders of magnitude concentration of proteins and tissue leakages. The changes in the abundance of these proteins have played an important role in various human ...

journal_title：PeerJ

authors： Madda R,Lin SC,Sun WH,Huang SL

更新日期：2018-05-08 00:00:00

abstract：Background:Many fish taxa produce sound in voluntary and in disturbance contexts but information on the full acoustic repertoire is lacking for most species. Yet, this knowledge is critical to enable monitoring fish populations in nature through acoustic monitoring. Methods:In this study we characterized the sounds em...

journal_title：PeerJ

authors： Pereira BP,Vieira M,Pousão-Ferreira P,Candeias-Mendes A,Barata M,Fonseca PJ,Amorim MCP

更新日期：2020-02-24 00:00:00

abstract：Background:The objective of the present study was to compare the effects of equal-volume resistance training (RT) performed with different training frequencies on muscle size and strength in trained young men. Methods:Sixteen men with at least one year of RT experience were divided into two groups, G1 and G2, that tra...

journal_title：PeerJ

authors： Gentil P,Fisher J,Steele J,Campos MH,Silva MH,Paoli A,Giessing J,Bottaro M

更新日期：2018-06-22 00:00:00

abstract：:A cervical vertebra of the large, pelagic pterodactyloid pterosaur Pteranodon sp. from the Late Cretaceous Niobrara Formation of Kansas, USA is significant for its association with a tooth from the large lamniform shark, Cretoxyrhina mantelli. Though the tooth does not pierce the vertebral periosteum, the intimate ass...

journal_title：PeerJ

authors： Hone DWE,Witton MP,Habib MB

更新日期：2018-12-14 00:00:00

abstract：:Background. Climate change concurrent with anthropogenic disturbances can initiate serial changes that reverberate up the food chain with repercussions for fisheries. To date, there is no information available concerning the combined effects of global warming and human impacts on tropical marine food webs. While tempe...

journal_title：PeerJ

authors： Chew LL,Chong VC

更新日期：2016-05-24 00:00:00

abstract：:Flies use specialized photoreceptors R7 and R8 in the dorsal rim area (DRA) to detect skylight polarization. R7 and R8 form a tiered waveguide (central rhabdomere pair, CRP) with R7 on top, filtering light delivered to R8. We examine how the division of a given resource, CRP length, between R7 and R8 affects their abi...

journal_title：PeerJ

authors： Heras FJ,Laughlin SB

更新日期：2017-01-12 00:00:00

abstract：:Hydrozoa medusae undergo blooms and seasonal fluctuations; however the drivers of such fluctuations are unknown. To understand how medusa populations fluctuate in response to seasonal factors such as temperature, salinity, dissolved oxygen, and chlorophyll a, and to enhance our taxonomic knowledge of Hydrozoa in Galve...

journal_title：PeerJ

authors： Pruski S,Miglietta MP

更新日期：2019-10-08 00:00:00

abstract：:Although C-type cytoplasmic male sterility (CMS-C) is one of the most attractive tools for maize hybrid seed production, the detailed regulation network of the male sterility remains unclear. In order to identify the CMS-C sterility associated genes and/or pathways, the comparison of the transcriptomes between the CMS...

journal_title：PeerJ

authors： Li C,Zhao Z,Liu Y,Liang B,Guan S,Lan H,Wang J,Lu Y,Cao M

更新日期：2017-05-30 00:00:00

abstract：Background:Circadian genes have been suggested to play an important role in lung pathology. However, it remains unknown whether polymorphisms of these genes are associated with chronic obstructive pulmonary disease (COPD). Here, we aimed to investigate the association of circadian genes polymorphisms with COPD in a cas...

journal_title：PeerJ

authors： Chen G,Zhang J,Zhang L,Xiong X,Yu D,Zhang Y

更新日期：2020-08-27 00:00:00

abstract：Background:In the absence of highly effective antiviral therapies against SARS-CoV-2, it is crucial to counter the known pathophysiological causes of severe COVID-19. Evaluating the efficacy existing drugs may expedite the development of such therapeutics. Severe COVID-19 is largely the result of a dysregulated immune ...

journal_title：PeerJ

authors： Kaye AG,Siegel R

更新日期：2020-11-02 00:00:00

abstract：:The genus Pseudostegana (Okada, 1978) currently contains thirty-nine described species. A number of Pseudostegana were collected from the fieldwork in southwestern China from 2010 to 2017. Eleven new species were discovered and are described from southwestern China: Pseudostegana alpina Zhang & Chen, sp. nov.; Pseudos...

journal_title：PeerJ

authors： Lu J,Zhang Y,Chen H

更新日期：2018-09-05 00:00:00

abstract：:A striking and unexpected biochemical phenotype was found in an insertion mutant line in the model plant Arabidopsis thaliana. One of two investigated insertion mutant lines in the gene encoding the phosphate transporter PHT4;1 demonstrated a prominent loss of trienoic fatty acids, whereas the other insertion line was...

journal_title：PeerJ

authors： Nilsson AK,Andersson MX

更新日期：2017-12-01 00:00:00

abstract：:Diffuse sources of pollution like agricultural or urban runoff are important factors in determining the quality of surface waters, although they are more difficult to monitor than point sources. The objective of our study was to verify assumptions that the inflow from agricultural nutrient sources is higher than from ...

journal_title：PeerJ

authors： Matej-Lukowicz K,Wojciechowska E,Nawrot N,Dzierzbicka-Głowacka LA

更新日期：2020-02-06 00:00:00

abstract：Background:Alzheimer's disease (AD) is a prevalent progressive neurodegenerative human disease whose cause remains unclear. Numerous initially highly hopeful anti-AD drugs based on the amyloid-β (Aβ) hypothesis of AD have failed recent late-phase tests. Natural aging (AG) is a high-risk factor for AD. Here, we aim to g...

journal_title：PeerJ

authors： Peng YS,Tang CW,Peng YY,Chang H,Chen CL,Guo SL,Wu LC,Huang MC,Lee HC

更新日期：2020-03-20 00:00:00