Identification of special key genes for alcohol-related hepatocellular carcinoma through bioinformatic analysis.

abstract：:Although C-type cytoplasmic male sterility (CMS-C) is one of the most attractive tools for maize hybrid seed production, the detailed regulation network of the male sterility remains unclear. In order to identify the CMS-C sterility associated genes and/or pathways, the comparison of the transcriptomes between the CMS...

journal_title：PeerJ

authors： Li C,Zhao Z,Liu Y,Liang B,Guan S,Lan H,Wang J,Lu Y,Cao M

更新日期：2017-05-30 00:00:00

abstract：:Alcohol drinking may be associated with an increased risk of various metabolic diseases. Rat lines selectively bred for alcohol preference and alcohol avoidance constitute an interesting model to study inherited factors related to alcohol drinking and metabolic disorders. The aim of the present study was to compare th...

journal_title：PeerJ

authors： Mierzejewski P,Zakrzewska A,Kuczyńska J,Wyszogrodzka E,Dominiak M

更新日期：2020-09-11 00:00:00

abstract：:In this paper, we map the distribution of scale-rayed wrasse Acantholabrus palloni in eastern Skagerrak based on a combination of verified and personally communicated angling records. Long thought to be occasional vagrants outside its known range in the eastern Atlantic Ocean and Mediterranean Sea, we ask if this rare...

journal_title：PeerJ

authors： Näslund J,Lundgren M

更新日期：2018-11-06 00:00:00

abstract：:Non-invasive measurements of glucocorticoid (GC) concentrations, including cortisol and corticosterone, serve as reliable indicators of adrenocortical activities and physiological stress loads in a variety of species. As an alternative to invasive analyses based on plasma, GC concentrations in saliva still represent s...

journal_title：PeerJ

authors： Nemeth M,Pschernig E,Wallner B,Millesi E

更新日期：2016-01-18 00:00:00

abstract：Background:Guanylurea is the main transformation product of the antidiabetic drug metformin, which is one of the most prescribed pharmaceuticals worldwide. Due to the high rate of microbial degradation of metformin in sewage treatment plants, guanylurea occurs in higher concentrations in surface waters than its parent ...

journal_title：PeerJ

authors： Jacob S,Knoll S,Huhn C,Köhler HR,Tisler S,Zwiener C,Triebskorn R

更新日期：2019-07-11 00:00:00

abstract：Background:High throughput DNA sequencing of bulk invertebrate samples or metabarcoding is becoming increasingly used to provide profiles of biological communities for environmental monitoring. As metabarcoding becomes more widely applied, new reference DNA barcodes linked to individual specimens identified by taxonomi...

journal_title：PeerJ

authors： Carew ME,Coleman RA,Hoffmann AA

更新日期：2018-06-13 00:00:00

abstract：:Climatic variables have been the main predictors employed in ecological niche modeling and species distribution modeling, although biotic interactions are known to affect species' spatial distributions via mechanisms such as predation, competition, and mutualism. Biotic interactions can affect species' responses to ab...

journal_title：PeerJ

authors： Simões MVP,Peterson AT

更新日期：2018-12-05 00:00:00

abstract：:Arbuscular mycorrhizal fungi (AMF) colonization, sampled at 32-50 days post-inoculation (dpi), was significantly reduced in suppressor of prosystemin-mediated responses2 (spr2) mutant tomato plants impaired in the ω-3 FATTY ACID DESATURASE7 (FAD7) gene that limits the generation of linolenic acid and, consequently, th...

journal_title：PeerJ

authors： Casarrubias-Castillo K,Montero-Vargas JM,Dabdoub-González N,Winkler R,Martinez-Gallardo NA,Zañudo-Hernández J,Avilés-Arnaut H,Délano-Frier JP

更新日期：2020-04-16 00:00:00

abstract：:We revise the genus Conostigmus Dahlbom 1858 occurring in Madagascar, based on data from more specimens than were examined for the latest world revision of the genus. Our results yield new information about intraspecific variability and the nature of the atypical latitudinal diversity gradient (LDG) observed in Ceraph...

journal_title：PeerJ

authors： Mikó I,Trietsch C,Sandall EL,Yoder MJ,Hines H,Deans AR

更新日期：2016-12-13 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involved in HCC through multidimensional methods and revealed potential mole...

journal_title：PeerJ

authors： Liu ZK,Zhang RY,Yong YL,Zhang ZY,Li C,Chen ZN,Bian H

更新日期：2019-08-08 00:00:00

abstract：:Ichthyosaur fossils are abundant in Lower Jurassic sediments with nine genera found in the UK. In this paper, we describe the partial skeleton of a large ichthyosaur from the Lower Jurassic (lower Sinemurian) of Warwickshire, England, which was conserved and rearticulated to form the centrepiece of a new permanent gal...

journal_title：PeerJ

authors： Lomax DR,Porro LB,Larkin NR

更新日期：2019-01-08 00:00:00

abstract：:Herbivory and nutrient enrichment are drivers of benthic dynamics of coral reef macroalgae; however, their impact may vary seasonally. In this study we evaluated the effects of herbivore pressure, nutrient availability and potential propagule supply on seasonal recruitment and succession of macroalgal communities on a...

journal_title：PeerJ

authors： Duran A,Collado-Vides L,Burkepile DE

更新日期：2016-11-02 00:00:00

abstract：:Although anthophilous Coleoptera are regarded to be unspecialised flower-visiting insects, monkey beetles (Scarabaeidae: Hopliini) represent one of the most important groups of pollinating insects in South Africa's floristic hotspot of the Greater Cape Region. South African monkey beetles are known to feed on floral t...

journal_title：PeerJ

authors： Karolyi F,Hansal T,Krenn HW,Colville JF

更新日期：2016-01-21 00:00:00

abstract：:Biological carbon sequestration by forest ecosystems plays an important role in the net balance of greenhouse gases, acting as a carbon sink for anthropogenic CO2 emissions. Nevertheless, relatively little is known about the abiotic environmental factors (including climate) that control carbon storage in temperate and...

journal_title：PeerJ

authors： Duchesne L,Houle D,Ouimet R,Lambert MC,Logan T

更新日期：2016-03-03 00:00:00

abstract：Background:Geographic variation in body size and condition can reveal differential local adaptation to resource availability or climatic factors. Body size and condition are related to fitness in garter snakes (Thamnophis), thus good body condition may increase survival, fecundity in females, and mating success in male...

journal_title：PeerJ

authors： Valencia-Flores E,Venegas-Barrera CS,Fajardo V,Manjarrez J

更新日期：2019-03-13 00:00:00

abstract：INTRODUCTION:Early detection of social anxiety and loneliness might be useful to prevent substantial impairment in personal relationships. Understanding the way people use smartphones can be beneficial for implementing an early detection of social anxiety and loneliness. This paper examines different types of smartphon...

journal_title：PeerJ

authors： Gao Y,Li A,Zhu T,Liu X,Liu X

更新日期：2016-07-12 00:00:00

abstract：:Gelatin hydrogel crosslinked by microbial transglutaminase (mTG) exhibits excellent performance in cell adhesion, proliferation, and differentiation. We examined the gelation time and gel strength of gelatin/mTG hydrogels in various proportions to investigate their physical properties and tested their degradation perf...

journal_title：PeerJ

authors： Yang G,Xiao Z,Ren X,Long H,Qian H,Ma K,Guo Y

更新日期：2016-09-27 00:00:00

abstract：Background:Electrochemical signals play an important role in cell communication and behavior. Electrically charged ions transported across cell membranes maintain an electrochemical imbalance that gives rise to bioelectric signaling, called membrane potential or Vmem. Vmem plays a key role in numerous inter- and intrac...

journal_title：PeerJ

authors： Bhavsar MB,Cato G,Hauschild A,Leppik L,Costa Oliveira KM,Eischen-Loges MJ,Barker JH

更新日期：2019-02-08 00:00:00

abstract：:Although many ecologists focus on the relationship between species richness (S) and evenness (E), conflicts between observation and theory are difficult to reconcile. Empirical S-E relationships were not consistent, while relationships show strong correlation between S and E. Since E essentially depended on the relati...

journal_title：PeerJ

authors： Su Q

更新日期：2018-06-12 00:00:00

abstract：:We have developed a novel bio-tofu, made from mixed soy and cow milk (MSCM), using Lactobacillus helveticus MB2-1 and Lactobacillus plantarum B1-6 incorporated with microbial transglutaminase (MTGase) as coagulant. MTGase was added to improve the textural properties and suit for cooking. However, the effect of MTGase ...

journal_title：PeerJ

authors： Xing G,Rui X,Jiang M,Xiao Y,Guan Y,Wang D,Dong M

更新日期：2016-12-15 00:00:00

abstract：BACKGROUND:The present study investigated differences in reading and spelling outcomes in Dutch and English as a second language (ESL) in adolescents with a high familial risk of dyslexia, of whom some have developed dyslexia (HRDys) while others have not (HRnonDys), in comparison to a low familial risk control group w...

journal_title：PeerJ

authors： van Setten ERH,Tops W,Hakvoort BE,van der Leij A,Maurits NM,Maassen BAM

更新日期：2017-10-16 00:00:00

abstract：:Diffuse sources of pollution like agricultural or urban runoff are important factors in determining the quality of surface waters, although they are more difficult to monitor than point sources. The objective of our study was to verify assumptions that the inflow from agricultural nutrient sources is higher than from ...

journal_title：PeerJ

authors： Matej-Lukowicz K,Wojciechowska E,Nawrot N,Dzierzbicka-Głowacka LA

更新日期：2020-02-06 00:00:00

abstract：:The emergence of herbicide-resistant weeds is a major threat facing modern agriculture. Over 470 weedy-plant populations have developed resistance to herbicides. Traditional evolutionary mechanisms are not always sufficient to explain the rapidity with which certain weed populations adapt in response to herbicide expo...

journal_title：PeerJ

authors： Kim G,Clarke CR,Larose H,Tran HT,Haak DC,Zhang L,Askew S,Barney J,Westwood JH

更新日期：2017-07-20 00:00:00

abstract：:Background. A large proportion of natural grasslands around the world is exposed to overgrazing resulting in land degradation and biodiversity loss. Although there is an increasing effort in the promotion of sustainable livestock management, rangeland degradation still occurs because animals' foraging behaviour is hig...

journal_title：PeerJ

authors： di Virgilio A,Morales JM

更新日期：2016-06-21 00:00:00

abstract：:Demand for lumpfish (Cyclopterus lumpus) has increased exponentially over the last decade, both for their roe, which is used as a caviar substitute, and increasingly also as cleaner fish to control sea lice in salmon farming. The species is classified as Near Threatened by the IUCN and there are growing concerns that ...

journal_title：PeerJ

authors： Whittaker BA,Consuegra S,Garcia de Leaniz C

更新日期：2018-11-20 00:00:00

abstract：:A new species of freshwater crab, Fredius ibiapaba, is described and illustrated from a mid-altitude forested patch in Ipú (Ibiapaba plateau, Ceará, northeastern Brazil), between 635 to 782 m. The new species can be separated from its congeners by the morphology of its first gonopod: proximal half remarkably swollen, ...

journal_title：PeerJ

authors： Santos LC,Tavares M,Silva JRF,Cervini M,Pinheiro AP,Santana W

更新日期：2020-06-29 00:00:00

abstract：Background:BRCA1 and BRCA2 genes are currently proven to be closely related to high lifetime risks of breast cancer. To date, the closely related genes to BRCA1/2 mutations in breast cancer remains to be fully elucidated. This study aims to identify the gene expression profiles and interaction networks influenced by BR...

journal_title：PeerJ

authors： Li Y,Zhou X,Liu J,Yin Y,Yuan X,Yang R,Wang Q,Ji J,He Q

更新日期：2020-01-21 00:00:00

abstract：:Allium tenuissimum L. is a widely distributed perennial herbaceous species in temperate and desert steppes. Relative to other wild Allium species, it produces unique sweet flavors, more biomass in arid and cold environments, and has generated greater interest for crop production. Successful crop establishment, however...

journal_title：PeerJ

authors： Xiao H,Yang H,Monaco T,Song Q,Rong Y

更新日期：2020-04-07 00:00:00

abstract：Background:The problem of access to medical information, particularly in low-income countries, has been under discussion for many years. Although a number of developments have occurred in the last decade (e.g., the open access (OA) movement and the website Sci-Hub), everyone agrees that these difficulties still persist...

journal_title：PeerJ

authors： Boudry C,Alvarez-Muñoz P,Arencibia-Jorge R,Ayena D,Brouwer NJ,Chaudhuri Z,Chawner B,Epee E,Erraïs K,Fotouhi A,Gharaibeh AM,Hassanein DH,Herwig-Carl MC,Howard K,Kaimbo Wa Kaimbo D,Laughrea PA,Lopez FA,Machin-Mastromatteo

更新日期：2019-10-30 00:00:00

abstract：Background:The diagnosis of congenital heart defects is challenging, especially for what concerns conotruncal anomalies. Indeed, although the screening techniques of fetal cardiac anomalies have greatly improved, the detection rate of conotruncal anomalies still remains low due to the fact that they are associated with...

journal_title：PeerJ

authors： Dell'Oro S,Verderio M,Incerti M,Mastrolia SA,Cozzolino S,Vergani P

更新日期：2018-04-06 00:00:00